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NURSING MANAGEMENT OF 
MECHANICALLY VENTILATED 
PATIENTS 
Presented By 
Bibini Baby 
2nd year MSc. Nsg 
Govt. College of Nsg 
Kottayam 
1
Spontaneous respiration vs. 
Mechanical ventilation 
• Natural Breathing 
– Negative inspiratory force 
– Air pulled into lungs 
• Mechanical Ventilation 
– Positive inspiratory pressure 
– Air pushed into lungs 
2
Mechanical ventilation 
• Negative pressure 
• Positive pressure 
 Invasive 
 Noninvasive 
3
Negative-Pressure Ventilators 
• Early negative-pressure ventilators were 
known as “iron lungs.” 
• The patient’s body was encased in an iron 
cylinder and negative pressure was generated 
• The iron lung are still occasionally used 
today. 
4
5
• Intermittent short-term negative-pressure 
ventilation is sometimes used in patients with 
chronic diseases. 
• The use of negative-pressure ventilators is 
restricted in clinical practice, however, because they 
limit positioning and movement and they lack 
adaptability to large or small body torsos (chests) . 
• Our focus will be on the positive-pressure 
ventilators. 
6
POSITIVE PRESSURE VENTILATION 
(INVASIVE) 
7
Initiation of Mechanical Ventilation 
• Indications 
– Indications for Ventilatory Support 
–Acute Respiratory Failure 
–Prophylactic Ventilatory Support 
–Hyperventilation Therapy 
8
Initiation of Mechanical Ventilation 
• Indications 
– Acute Respiratory Failure (ARF) 
• Hypoxic lung failure (Type I) 
– Ventilation/perfusion mismatch 
– Diffusion defect 
– Right-to-left shunt 
– Alveolar hypoventilation 
– Decreased inspired oxygen 
– Acute life-threatening or vital 
organ-threatening tissue hypoxia 9
Initiation of Mechanical Ventilation 
• Indications 
– Acute Respiratory Failure (ARF) 
• Acute Hypercapnic Respiratory Failure (Type II) 
– CNS Disorders 
Âť Reduced Drive To Breathe: depressant 
drugs, brain or brainstem lesions (stroke, 
trauma, tumors), hypothyroidism 
Âť Increased Drive to Breathe: increased 
metabolic rate (CO2 production), 
metabolic acidosis, anxiety associated with 
dyspnea 
10
Initiation of Mechanical Ventilation 
• Indications 
– Acute Respiratory Failure (ARF) 
• Acute Hypercapnic Respiratory Failure (Type II) 
– Neuromuscular Disorders 
Âť Paralytic Disorders: Myasthenia Gravis, Guillain- 
Barre´11, poliomyelitis, etc. 
Âť Paralytic Drugs: Curare, nerve gas, succinylcholine, 
insecticides 
Âť Drugs that affect neuromuscular transmission; 
calcium channel blockers, long-term 
adenocorticosteroids, etc. 
Âť Impaired Muscle Function: electrolyte imbalance, 
malnutrition, chronic pulmonary disease, etc. 11
Initiation of Mechanical Ventilation 
• Indications 
– Acute Respiratory Failure (ARF) 
• Acute Hypercapnic Respiratory Failure 
– Increased Work of Breathing 
Âť Pleural Occupying Lesions: pleural effusions, 
hemothorax, empyema, pneumothorax 
Âť Chest Wall Deformities: flail chest, kyphoscoliosis, 
obesity 
Âť Increased Airway Resistance: secretions, mucosal 
edema, bronchoconstriction, foreign body 
Âť Lung Tissue Involvement: interstitial pulmonary 
fibrotic diseases 
12
Initiation of Mechanical Ventilation 
• Indications 
– Acute Respiratory Failure (ARF) 
• Acute Hypercapnic Respiratory Failure 
– Increased Work of Breathing (cont.) 
Âť Lung Tissue Involvement: interstitial pulmonary 
fibrotic diseases, aspiration, ARDS, cardiogenic PE, 
drug induced PE 
Âť Pulmonary Vascular Problems: pulmonary 
thromboembolism, pulmonary vascular damage 
Âť Dynamic Hyperinflation (air trapping) 
Âť Postoperative Pulmonary Complications 
13
Initiation of Mechanical Ventilation 
• Prophylactic Ventilatory Support 
– Clinical conditions in which there is a high risk of 
future respiratory failure 
• Examples: Brain injury, heart muscle injury, major 
surgery, prolonged shock, smoke injury 
• Ventilatory support is instituted to: 
–Decrease the WOB 
–Minimize O2 consumption and hypoxemia 
–Reduce cardiopulmonary stress 
–Control airway with sedation 14
Initiation of Mechanical Ventilation 
• Hyperventilation Therapy 
– Ventilatory support is instituted to control and 
manipulate PaCO2 to lower than normal levels 
• Acute head injury 
15
Criteria for institution of ventilatory 
support: 
Normal 
range 
Ventilation 
indicated 
Parameters 
10-20 
5-7 
65-75 
75-100 
> 35 
< 5 
< 15 
<-20 
A- Pulmonary function 
studies: 
• Respiratory rate 
(breaths/min). 
• Tidal volume (ml/kg 
body wt) 
• Vital capacity (ml/kg 
body wt) 
• Maximum Inspiratory 
Force (cm HO2) 
16
Criteria for institution of ventilatory 
support: 
Normal 
range 
Ventilation 
indicated 
Parameters 
7.35-7.45 
75-100 
35-45 
< 7.25 
< 60 
> 50 
B- Arterial blood 
Gases 
• PH 
• PaO2 (mmHg) 
• PaCO2 (mmHg) 
17
Initiation of Mechanical Ventilation 
• Contraindications 
– Untreated pneumothorax 
• Relative Contraindications 
– Patient’s informed consent 
– Medical futility 
– Reduction or termination of patient pain 
and suffering 
18
Essential components in mechanical 
ventilation 
• Patient 
• Artificial airway 
• Ventilator circuit 
• Mechanical ventilator 
• A/c or D/c power source 
• O2 cylinder or central oxygen supply 
19
Artificial airways 
• Tracheal intubation 
– Nasal 
– Oral 
• Supraglottic airway 
• Cricothyrotomy 
• Tracheostomy 
20
Laryngeal airway 
21
Intubation Procedure 
Check and Assemble Equipment: 
Oxygen flowmeter and O2 tubing 
Suction apparatus and tubing 
Suction catheter 
Ambu bag and mask 
Laryngoscope with assorted blades 
3 sizes of ET tubes 
Stillet 
Stethoscope 
Tape 
Syringe 
Sterile gloves
Intubation Procedure 
Position your patient into the sniffing 
position
Intubation Procedure 
Preoxygenate with 100% oxygen to 
provide apneic or distressed patient 
with reserve while attempting to 
intubate. 
Do not allow more than 30 seconds to any 
intubation attempt. 
If intubation is unsuccessful, ventilate 
with 100% oxygen for 3-5 minutes before 
a reattempt.
Intubation Procedure 
Insert Laryngoscope
Intubation Procedure 
After displacing the epiglottis insert the ETT. 
The depth of the tube for a male patient on 
average is 21-23 cm at teeth 
The depth of the tube on average for a female 
patient is 19-21 at teeth.
Intubation Procedure 
Confirm tube position: 
By auscultation of the chest 
Bilateral chest rise 
Tube location at teeth 
CO2 detector – (esophageal 
detection device or by 
capnography)
Intubation Procedure 
Stabilize the ETT
Ventilator circuit 
• Breathing System Plain 
• Breathing System with Single Water Trap 
• Breathing System with Double Water Trap. 
• Breathing Filters HME Filter 
• Flexible Catheter Mount 
29
30 
Ventilator circuit 
Breathing system plain
31 
Ventilator Breathing System (1.6m)
32 
Ventilator Breathing System (1.6m)
heat & moisture exchanger HME filter 
33
34
MECHANICAL VENTILATOR 
• A mechanical ventilator is a machine that 
generates a controlled flow of gas into a 
patient’s airways. Oxygen and air are received 
from cylinders or wall outlets, the gas is 
pressure reduced and blended according to 
the prescribed inspired oxygen tension (FiO2), 
accumulated in a receptacle within the 
machine, and delivered to the patient using 
one of many available modes of ventilation. 
35
Types of Mechanical ventilators 
• Transport ventilators 
• Intensive-care ventilators 
• Neonatal ventilators 
• Positive airway pressure ventilators for NIV 
36
Classification of positive-pressure ventilators 
• Ventilators are classified according to how the 
inspiratory phase ends. The factor which terminates 
the inspiratory cycle reflects the machine type. 
• They are classified as: 
1- Pressure cycled ventilator 
2- Volume cycled ventilator 
3- Time cycled ventilator 
37
1- Volume-cycled ventilator 
• Inspiration is terminated after a preset tidal 
volume has been delivered by the ventilator. 
• The ventilator delivers a preset tidal volume 
(VT), and inspiration stops when the preset 
tidal volume is achieved. 
38
2- Pressure-cycled ventilator 
• In which inspiration is terminated when a 
specific airway pressure has been reached. 
• The ventilator delivers a preset pressure; 
once this pressure is achieved, end 
inspiration occurs. 
39
3- Time-cycled ventilator 
• In which inspiration is terminated when a 
preset inspiratory time, has elapsed. 
• Time cycled machines are not used in adult 
critical care settings. They are used in 
pediatric intensive care areas. 
40
Mechanical Ventilators 
Different Types of Ventilators Available: 
Will depend on your place of employment 
Ventilators in use in MCH 
Servo S by Maquet 
Savina by Drager
42
43
MODES OF VENTILATION
Ventilator mode 
• The way the machine ventilates the patient 
• How much the patient will participate in his 
own ventilatory pattern. 
• Each mode is different in determining how 
much work of breathing the patient has to 
do. 
45
A- Volume Modes 
• 1. CMV or CV 
• 2. AMV or AV 
• 3. IMV 
• 4. SIMV 
46
B- Pressure Modes 
1- Pressure-controlled ventilation (PCV) 
2- Pressure-support ventilation (PSV) 
3- Continuous positive airway pressure 
(CPAP) 
4- Positive end expiratory pressure (PEEP) 
5- Noninvasive bilevel positive airway pressure 
ventilation (BiPAP) 
47
Control Mode 
Delivers pre-set volumes at a pre-set rate and 
a pre-set flow rate. 
The patient CANNOT generate spontaneous 
breaths, volumes, or flow rates in this mode.
Control Mode
Assist/Control Mode 
•Delivers pre-set volumes at a pre-set 
rate and a pre-set flow rate. 
•The patient CANNOT generate 
spontaneous volumes, or flow rates in 
this mode. 
•Each patient generated respiratory effort 
over and above the set rate are delivered 
at the set volume and flow rate.
Assist Control 
• Volume or Pressure control mode 
• Parameters to set: 
– Volume or pressure 
– Rate 
– I – time 
– FiO2 
51
Assist Control 
• Machine breaths: 
– Delivers the set volume or pressure 
• Patient’s spontaneous breath: 
– Ventilator delivers full set volume or pressure & 
I-time 
• Mode of ventilation provides the most 
support 
52
Negative deflection, 
triggering assisted 
breath 
Assist Control
SYCHRONIZED INTERMITTENT 
MANDATORY VENTILATION 
(SIMV): 
Delivers a pre-set number of breaths at a 
set volume and flow rate. 
Allows the patient to generate 
spontaneous breaths, volumes, and flow 
rates between the set breaths. 
Detects a patient’s spontaneous breath 
attempt and doesn’t initiate a ventilatory 
breath – prevents breath stacking
SIMV 
Synchronized intermittent mandatory ventilation 
• Machine breaths: 
– Delivers the set volume or pressure 
• Patient’s spontaneous breath: 
– Set pressure support delivered 
• Mode of ventilation provides moderate amount of 
support 
• Works well as weaning mode 
55
SIMV cont. 
56 
Machine Breaths 
Spontaneous Breaths
IMV 
57 
Ingento EP & Drazen J: Mechanical Ventilators, in Hall JB, Scmidt GA, & Wood 
LDH(eds.): Principles of Critical Care
58 
Volume Modes
PRESSURE REGULATED VOLUME 
CONTROL (PRVC): 
• This is a volume targeted, pressure limited 
mode. (available in SIMV or AC) 
• Each breath is delivered at a set volume with 
a variable flow rate and an absolute pressure 
limit. 
• The vent delivers this pre-set volume at the 
LOWEST required peak pressure and adjust 
with each breath. 
59
PRVC (Pressure regulated volume control) 
A control mode, which delivers a set tidal volume 
with each breath at the lowest possible peak 
pressure. 
Delivers the breath with a decelerating flow 
pattern that is thought to be less injurious to the 
lung…… “the guided hand”. 
60
PRCV: Advantages 
Decelerating inspiratory flow pattern 
Pressure automatically adjusted for changes in 
compliance and resistance within a set range 
Tidal volume guaranteed 
Limits volutrauma 
Prevents hypoventilation 
61
PRVC: Disadvantages 
Pressure delivered is dependent on tidal volume achieved on 
last breath 
Intermittent patient effort  variable tidal volumes 
Volume Flow Pressure 
Set tidal volume 
62 
Š Charles Gomersall 2003
PRVC: Disadvantages 
Pressure delivered is dependent on tidal volume achieved on 
Volume Flow Pressure 
last breath 
Intermittent patient effort  variable tidal volumes 
Set tidal volume 
63 
Š Charles Gomersall 2003
PRVC 
64
POSITIVE END EXPIRATORY PRESSURE 
(PEEP): 
• This is NOT a specific mode, but is rather an 
adjunct to any of the vent modes. 
• PEEP is the amount of pressure remaining in 
the lung at the END of the expiratory phase. 
• Utilized to keep otherwise collapsing lung 
units open while hopefully also improving 
oxygenation. 
• Usually, 5-10 cmH2O 
65
66
Pplat 
• Measured by occluding the ventilator 3-5 sec at 
the end of inspiration 
• Should not exceed 30 cmH2O 
67
Peak Pressure (Ppeak) 
• Ppeak = Pplat + Pres 
Where Pres reflects the resistive element of 
the respiratory system (ET tube and airway) 
68
Ppeak 
• Pressure measured at the end of inspiration 
• Should not exceed 50cmH2O? 
69
Auto-PEEP or Intrinsic PEEP 
– Normally, at end expiration, the lung volume is 
equal to the FRC 
– When PEEPi occurs, the lung volume at end 
expiration is greater than the FRC 
70
Auto-PEEP or Intrinsic PEEP 
• Why does hyperinflation occur? 
– Airflow limitation because of dynamic collapse 
– No time to expire all the lung volume (high RR or 
Vt) 
– Decreased Expiratory muscle activity 
– Lesions that increase expiratory resistance 
71
Auto-PEEP or Intrinsic PEEP 
• Adverse effects: 
– Predisposes to barotrauma 
– Predisposes hemodynamic compromises 
– Diminishes the efficiency of the force generated by 
respiratory muscles 
– Augments the work of breathing 
– Augments the effort to trigger the ventilator 
72
• This is a mode and simply means that a pre-set 
pressure is present in the circuit and lungs 
throughout both the inspiratory and 
expiratory phases of the breath. 
• CPAP serves to keep alveoli from collapsing, 
resulting in better oxygenation and less WOB. 
• The CPAP mode is very commonly used as a 
mode to evaluate the patients readiness for 
extubation. 
73 
Continuous Positive Airway Pressure 
(CPAP):
Combination “Dual Control” Modes 
Combination or “dual control” modes combine features 
of pressure and volume targeting to accomplish 
ventilatory objectives which might remain unmet by 
either used independently. 
Combination modes are pressure targeted 
Partial support is generally provided by pressure support 
Full support is provided by Pressure Control 
74
Combination “Dual Control” Modes 
Volume Assured Pressure Support 
(Pressure Augmentation) 
Volume Support 
(Variable Pressure Support) 
Pressure Regulated Volume Control 
(Variable Pressure Control, or Autoflow) 
Airway Pressure Release 
(Bi-Level, Bi-PAP) 
75
• Inverse ratio ventilation (IRV) mode reverses this 
ratio so that inspiratory time is equal to, or longer 
than, expiratory time (1:1 to 4:1). 
• Inverse I:E ratios are used in conjunction with 
pressure control to improve oxygenation by 
expanding stiff alveoli by using longer distending 
times, thereby providing more opportunity for gas 
exchange and preventing alveolar collapse. 
76
• As expiratory time is decreased, one must monitor 
for the development of hyperinflation or auto-PEEP. 
Regional alveolar overdistension and 
barotrauma may occur owing to excessive total 
PEEP. 
• When the PCV mode is used, the mean airway and 
intrathoracic pressures rise, potentially resulting in 
a decrease in cardiac output and oxygen delivery. 
Therefore, the patient’s hemodynamic status must 
be monitored closely. 
• Used to limit plateau pressures that can cause 
barotrauma & Severe ARDS 
77
HIGH FREQUENCY OSCILLATORY 
VENTILATION
HIFI - Theory 
• Resonant frequency phenomena: 
– Lungs have a natural resonant frequency 
– Outside force used to overcome airway resistance 
• Use of high velocity inspiratory gas flow: 
reduction of effective dead space 
• Increased bulk flow: secondary to active 
expiration 
79
HIFI - Advantages 
• Advantages: 
– Decreased barotrauma / volutrauma: reduced swings 
in pressure and volume 
– Improve V/Q matching: secondary to different flow 
delivery characteristics 
• Disadvantages: 
– Greater potential of air trapping 
– Hemodynamic compromise 
– Physical airway damage: necrotizing tracheobronchitis 
– Difficult to suction 
– Often require paralysis 
80
HIFI – Clinical Application 
• Adjustable Parameters 
– Mean Airway Pressure: usually set 2-4 higher 
than MAP on conventional ventilator 
– Amplitude: monitor chest rise 
– Hertz: number of cycles per second 
– FiO2 
– I-time: usually set at 33% 
81
Comparison of HFOV 
& Conventional Ventilation 
Differences CMV HFOV 
Rates 0 - 150 180 - 900 
Tidal Volume 4 - 20 ml/kg 0.1 - 3 ml/kg 
Alveolar Press 0 - > 50 cmH2O 0.1 - 5 cmH2O 
End Exp Volume Low Normalized 
Gas Flow Low High 
82
Video on HFOV 
http://youtube.com/watch?v=jLroOPoPlig 
83
INITIAL SETTINGS 
84 
• Select your mode of ventilation 
• Set sensitivity at Flow trigger mode 
• Set Tidal Volume 
• Set Rate 
• Set Inspiratory Flow (if necessary) 
• Set PEEP 
• Set Pressure Limit 
• Inspiratory time 
• Fraction of inspired oxygen
Trigger 
 There are two ways to initiate a ventilator-delivered 
breath: pressure triggering or flow-by triggering 
 When pressure triggering is used, a ventilator-delivered 
breath is initiated if the demand valve senses a negative 
airway pressure deflection (generated by the patient 
trying to initiate a breath) greater than the trigger 
sensitivity. 
 When flow-by triggering is used, a continuous flow of gas 
through the ventilator circuit is monitored. A ventilator-delivered 
breath is initiated when the return flow is less 
than the delivered flow, a consequence of the patient's 
effort to initiate a breath 85
Post Initial Settings 
86 
• Obtain an ABG (arterial blood gas) about 30 
minutes after you set your patient up on 
the ventilator. 
• An ABG will give you information about any 
changes that may need to be made to keep 
the patient’s oxygenation and ventilation 
status within a physiological range.
ABG 
87 
• Goal: 
• Keep patient’s acid/base balance within 
normal range: 
• pH 7.35 – 7.45 
• PCO2 35-45 mmHg 
• PO2 80-100 mmHg
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Tidal Volume 
• Spontaneous VT for an adult is 5 – 7 ml/kg of IBW 
Determining VT for Ventilated Patients 
• A range of 6 – 12 ml/kg IBW is used for adults 
– 10 – 12 ml/kg IBW (normal lung function) 
– 8 – 10 ml/kg IBW (obstructive lung disease) 
– 6 – 8 ml/kg IBW (ARDS) – can be as low as 4 ml/kg 
• A range of 5 – 10 ml/kg IBW is used for infants and 
children 
88
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Respiratory Rate 
• Normal respiratory rate is 12-18 
breaths/min. 
• A range of 8 – 12 breaths per minute (BPM) 
Rates should be adjusted to try and minimize auto- 
PEEP 
89
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Minute Ventilation 
• Respiratory rate is chosen in conjunction with tidal 
volume to provide an acceptable minute ventilation 
= VT x f 
• Normal minute ventilation is 5-10 L/min 
• Estimated by using 100 mL/kg IBW 
• ABG needed to assess effectiveness of initial settings 
– If PaCO2 >45 ( minute ventilation via f or VT) 
– If PaCO2 <35 ( minute ventilation via f or VT) 
90
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Inspiratory Flow 
• Rate of Gas Flow 
– As a beginning point, flow is normal set to deliver 
inspiration in about 1 second (range 0.8 to 1.2 sec.), 
producing an I:E ratio of approximately 1:2 or less (usually 
about 1:4) 
– This can be achieved with an initial peak flow of about 60 
L/min (range of 40 to 80 L/min) 
Most importantly, flows are set to meet a patient’s inspiratory 
demand 
91
Expiratory Flow Pattern 
92 
Inspiration 
Expiration 
Time (sec) 
Flow (L/min) 
Beginning of expiration 
exhalation valve opens 
Peak Expiratory Flow Rate 
PEFR 
Duration of 
expiratory flow 
Expiratory time 
TE
Initiation of Mechanical Ventilation 
– Flow Patterns 
• Selection of flow pattern and flow rate may depend on 
the patient’s lung condition, e.g., 
– Post – operative patient recovering from anesthesia 
may have very modest flow demands 
– Young adult with pneumonia and a strong 
hypoxemic drive would have very strong flow 
demands 
– Normal lungs: Not of key importance 
93
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Flow Pattern 
• Constant Flow (rectangular or square waveform) 
– Generally provides the shortest TI 
– Some clinician choose to use a constant (square) flow 
pattern initially because it enables them to obtain baseline 
measurements of lung compliance and airway resistance 
94
Initiation of Mechanical Ventilation 
– Flow Pattern 
• Sine Flow 
– May contribute to a more even distribution of gas in the 
lungs 
– Peak pressures and mean airway pressure are about the 
same for sine and square wave patterns 
95
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Flow Pattern 
• Descending (decelerating) Ramp 
– Improves distribution of ventilation, results in a longer TI, 
decreased peak pressure, and increased mean airway 
pressure (which increases oxygenation) 
96
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– Positive End Expiratory Pressure (PEEP) 
• Initially set at 3 – 5 cm H2O 
– Restores FRC and physiological PEEP that existed prior 
to intubation 
– Subsequent changes are based on ABG results 
• Useful to treat refractory hypoxemia 
• Contraindications for therapeutic PEEP (>5 cm H2O) 
– Hypotension 
– Elevated ICP 
– Uncontrolled pneumothorax 
97
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings 
– FiO2 
• Initially 100% 
– Severe hypoxemia 
– Abnormal cardiopulmonary functions 
Âť Post-resuscitation 
Âť Smoke inhalation 
Âť ARDS 
• After stabilization, attempt to keep FiO2 <50% 
– Avoids oxygen-induced lung injuries 
Âť Absorption atelectasis 
Âť Oxygen toxicity 98
Initiation of Mechanical Ventilation 
– FiO2 of 40% or Same FiO2 prior to mechanical 
ventilation 
• Patients with mild hypoxemia or normal 
cardiopulmonary function 
–Drug overdose 
–Uncomplicated postoperative recovery 
99
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings For PCV 
– Rate, TI, and I:E ratio are set in PCV as they are 
in Volume mode 
– The pressure gradient (PIP-PEEP) is adjusted to 
establish volume delivery 
Remember: Volume delivery changes as lung 
characteristics change and can vary breath to 
breath 
100
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings For PCV 
– Flow Pattern 
• PCV provides a descending ramp 
waveform 
Note: The patient can vary the 
inspiratory flow on demand 
101
Initiation of Mechanical Ventilation 
• Initial Ventilator Settings For PCV 
– Rise Time (slope, flow acceleration) 
• Rise time is the amount of TI it takes for the 
ventilator to reach the set pressure at the beginning 
of inspiration 
• Inspiratory flow delivery during PCV can be adjusted 
with an inspiratory rise time control 
• Ventilator graphics can be used to set the rise time 
102
● Sigh 
• A deep breath. 
• A breath that has a greater volume than the tidal volume. 
• It provides hyperinflation and prevents atelectasis. 
• Sigh volume :------------------Usual volume is 1.5 –2 times tidal 
volume. 
• Sigh rate/ frequency :---------Usual rate is 4 to 8 times per 
hour. 
103
Ensuring humidification and 
thermoregulation 
• All air delivered by the ventilator passes through the water 
in the humidifier, where it is warmed and saturated or 
through an HME filter 
• Humidifier temperatures should be kept close to body 
temperature 35 ÂşC- 37ÂşC. 
• In some rare instances (severe hypothermia), the air 
temperatures can be increased. 
• The humidifier should be checked for adequate water levels 
104
Initiation of Mechanical Ventilation 
• Ventilator Alarm Settings 
– High Minute Ventilation 
• Set at 2 L/min or 10%-15% above baseline minute 
ventilation 
– Patient is becoming tachypneic (respiratory distress) 
– High Respiratory Rate Alarm 
• Set 10 – 15 BPM over observed respiratory rate 
– Patient is becoming tachypneic (respiratory distress) 
105
Initiation of Mechanical Ventilation 
• Ventilator Alarm Settings 
– Low Exhaled Tidal Volume Alarm 
• Set 100 ml or 10%-15% lower than expired mechanical tidal 
volume 
• Causes 
– System leak 
– Circuit disconnection 
– ET Tube cuff leak 
106
Initiation of Mechanical Ventilation 
• Ventilator Alarm Settings 
– High Inspiratory Pressure Alarm 
• Set 10 – 15 cm H2O above PIP 
• Common causes: 
–Water in circuit 
– Kinking or biting of ET Tube 
– Secretions in the airway 
– Bronchospasm 
– Tension pneumothorax 
– Decrease in lung compliance 
– Increase in airway resistance 
– Coughing 
107
Initiation of Mechanical Ventilation 
• Ventilator Alarm Settings 
– Low Inspiratory Pressure Alarm 
• Set 10 – 15 cm H2O below observed PIP 
• Causes 
– System leak 
– Circuit disconnection 
– ET Tube cuff leak 
– High/Low PEEP/CPAP Alarm (baseline alarm) 
• High: Set 3-5 cm H2O above PEEP 
– Circuit or exhalation manifold obstruction 
– Auto – PEEP 
• Low: Set 2-5 cm H2O below PEEP 
– Circuit disconnect 108
Initiation of Mechanical Ventilation 
• Ventilator Alarm Settings 
– High/Low FiO2 Alarm 
• High: 5% over the analyzed FiO2 
• Low: 5% below the analyzed FiO2 
– High/Low Temperature Alarm 
• Heated humidification 
– High: No higher than 37 C 
– Low: No lower than 30 C 
109
Initiation of Mechanical Ventilation 
• Ventilator Alarm Settings 
– Apnea Alarm 
• Set with a 15 – 20 second time delay 
• In some ventilators, this triggers an apnea 
ventilation mode 
– Apnea Ventilation Settings 
• Provide full ventilatory support if the patient 
become apneic 
• VT 8 – 12 mL/kg ideal body weight 
• Rate 10 – 12 breaths/min 
• FiO2 100% 
110
TROUBLESHOOTING 
111
Trouble Shooting the Vent 
• Common problems 
– High peak pressures 
– Patient with COPD 
– Ventilator asynchrony 
– ARDS 
112
Trouble Shooting the Vent 
• If peak pressures are increasing: 
– Check plateau pressures by allowing for an 
inspiratory pause (this gives you the pressure in 
the lung itself without the addition of resistance) 
– If peak pressures are high and plateau pressures 
are low then you have an obstruction 
– If both peak pressures and plateau pressures are 
high then you have a lung compliance issue 
113
Trouble Shooting the Vent 
• High peak pressure differential: 
114 
High Peak Pressures 
Low Plateau Pressures 
High Peak Pressures 
High Plateau Pressures 
Mucus Plug ARDS 
Bronchospasm Pulmonary Edema 
ET tube blockage Pneumothorax 
Biting ET tube migration to a single bronchus 
Effusion
COPD 
• If you have a patient with history of COPD/asthma with worsening 
oxygen saturation and increasing hypercapnia differential includes: 
– Must be concern with breath stacking or auto- PEEP 
– Low VT with increased exhalation time is advisable 
• Baseline ABGs reflect an elevated PaCO2 should not hyperventilated. 
Instead, the goal should be restoration of the baseline PaCO2. 
• These patients usually have a large carbonic acid load, and lowering 
their carbon dioxide levels rapidly may result in seizures. 
115
COPD and Asthma 
• Goals: 
– Diminish dynamic hyperinflation 
– Diminish work of breathing 
– Controlled hypoventilation (permissive 
hypercapnia) 
116
Trouble Shooting the Vent 
• Increase in patient agitation and dis-synchrony 
on the ventilator: 
– Could be secondary to overall discomfort 
• Increase sedation 
– Could be secondary to feelings of air hunger 
• Options include increasing tidal volume, increasing flow 
rate, adjusting I:E ratio, increasing sedation 
117
Trouble shooting the vent 
• If you are concern for acute respiratory 
distress syndrome (ARDS) 
– Correlate clinically with radiologic findings of 
diffuse patchy infiltrate on CXR 
– Obtain a PaO2/FiO2 ratio (if < 200 likely ARDS) 
– Begin ARDSnet protocol: 
• Low tidal volumes 
• Increase PEEP rather than FiO2 
• Consider increasing sedation to promote synchrony 
with ventilator 
118
Accidental Extubation 
• Role of the Nurse: 
– Ensure the Ambu bag is attached to the 
oxygen flowmeter and it is on! 
– Attach the face mask to the Ambu bag and 
after ensuring a good seal on the patient’s 
face; supply the patient with ventilation. 
119
Pulmonary Disease: Obstructive 
Airway obstruction causing increase resistance to airflow: e.g. 
asthma 
• Optimize expiratory time by minimizing minute ventilation 
• Bag slowly after intubation 
• Don’t increase ventilator rate for increased CO2 
120
Pulmonary Disease: Restrictive 
Compromised lung volume: 
– Intrinsic lung disease 
– External compression of lung 
• Recruit alveolia, optimize V/Q matching 
• Lung protective strategies 
– High PEEP 
– Pressure limiting PIP: 30-35 cmH2O 
– Low tidal volume: 4-8 ml/kg 
– FiO2 <60% 
– Permissive hypercarbia 
– Permissive hypoxia 121
In a patient with head injury, 
• Respiratory alkalosis may be required to promote 
cerebral vasoconstriction, with a resultant decrease 
in ICP. 
• In this case, the tidal volume and respiratory rate 
are increased 
( hyperventilation) to achieve the desired alkalotic 
pH by manipulating the PaCO2. 
122
Complications 
of Mechanical Ventilation:- 
I- Airway Complications, 
II- Mechanical complications, 
III- Physiological Complications, 
IV- Artificial Airway Complications. 
123
I- Airway Complications 
1- Aspiration 
2- Decreased clearance of secretions 
3- Nosocomial or ventilator-acquired 
pneumonia 
124
125
WHAT IS SUCTIONING?..... 
The patient with an artificial 
airway is not capable of effectively 
coughing, the mobilization of 
secretions from the trachea must be 
facilitated by aspiration. This is 
called as suctioning.
Indications 
 Coarse breath sounds 
 Noisy breathing 
 Visible secretions in the airway 
 Decreased SpO2 in the pulse oximeter & Deterioration of 
arterial blood gas values 
 Clinically increased work of breathing 
 Changes in monitored flow/pressure graphics 
 Increased PIP; decreased Vt during ventilation
NECESSARY EQUIPMENT 
 Vaccum source with adjustable regulator 
suction jar 
 stethoscope 
 Sterile gloves for open suctioning method 
 Clean gloves for closed suctioning method 
 Sterile catheter 
 Clear protective goggles, apron & mask 
 Sterile normal saline 
 Bain’s circuit or ambu bag for 
preoxygenate the patient 
 Suction tray with hot water for flushing
TYPES OF SUCTIONING 
OPEN SUCTION CLOSED SUCTION
OPEN SUCTION SYSTEM: 
Regularly using system in the intubated 
patients. 
CLOSED SUCTION SYSTEM: 
 This is used to facilitate continuous 
mechanical ventilation and oxygenation during 
the suctioning. 
 Closed suctioning is also indicated when PEEP 
level above 10cmH2O.
Patient Preparation 
 Explain the procedure to the patient (If 
patient is concious). 
 The patient should receive hyper 
oxygenation by the delivery of 100% 
oxygen for >30 seconds prior to the 
suctioning (by increasing the FiO2 by 
mechanical ventilator). 
 Position the patient in supine position. 
 Auscultate the breath sounds.
PROCEDURE 
Perform hand hygiene, wash 
hands. It reduces transmission 
of microorganisms. 
Turn on suction apparatus and 
set vacuum regulator to 
appropriate negative pressure. 
For adult a pressure of 100-120 
mmHg, 80-100mmhg for 
children & 60-80mmhg for 
infants.
Continue….. 
Goggles, mask & apron should be worn 
to prevent splash from secretions 
Preoxygenate with 100% O2 
Open the end of the suction catheter 
package & connect it to suction tubing 
(If you are alone) 
Wear sterile gloves with sterile 
technique 
With a help of an assistant open suction 
catheter package & connect it to suction 
tubing
Continue….. 
With a help of an assistant disconnect 
the ventilator 
Kink the suction tube & insert the 
catheter in to the ETtube until resistance 
is felt 
Resistance is felt when the catheter 
impacts the carina or bronchial mucosa, 
the suction catheter should be 
withdrawn 1cm out before applying 
suction
Continue..... 
Apply continuous suction while rotating 
the suction catheter during removal 
The duration of each suctioning should 
be less the 15sec. 
Instill 3 to 5ml of sterile normal saline in 
to the artificial airway, if required 
Assistant resumes the ventilator 
Give four to five manual breaths with 
bag or ventilator
Continue….. 
 Continue making suction passes, bagging patient between 
passes, until clear of secretions, but no more than four 
passes 
 Return patient to ventilator 
 Flush the catheter with hot water in the suction tray 
 Suction nares & oropharynx above the artificial airway 
 Discard used equipments 
 Flush the suction tube with hot water 
 Auscultate chest 
Wash hands 
 Document including indications for suctioning & any 
changes in vitals & patient’s tolerance
Closed suctioning procedure 
Wash hands 
Wear clean gloves 
Connect tubing to closed suction 
port 
Pre-oxygenate the patient with 
100% O2 
Gently insert catheter tip into 
artificial airway without applying 
suction, stop if you met resistance 
or when patient starts coughing and 
pull back 1cm out
Closed suction 
138
Continue….. 
 Place the dominant thumb over 
the control vent of the suction 
port, applying continuous or 
intermittent suction for no more 
than 10 sec as you withdraw the 
catheter into the sterile sleeve of 
the closed suction device 
 Repeat steps above if needed 
 Clean suction catheter with sterile 
saline until clear; being careful not 
to instill solution into the ETtube 
 Suction oropharynx above the 
artificial airway 
Wash hands
ASSESSMENT OF OUTCOME 
Improvement in breath sounds. 
Decreased peak inspiratory pressure; 
Increased tidal volume delivery during 
ventilation. 
Improvement in arterial blood gas values or 
saturation as reflected by pulse oximetry. 
(SpO2) 
Removal of pulmonary secretions.
CONTRAINDICATIONS 
 Most contraindications are relative to the patient's 
risk of developing adverse reactions or worsening 
clinical condition as result of the procedure. 
 Suctioning is contraindicated when there is fresh 
bleeding. 
 When indicated, there is no absolute 
contraindication to endotracheal suctioning 
because the decision to abstain from suctioning in 
order to avoid a possible adverse reaction may, in 
fact, be lethal.
LIMITATIONS OF METHOD 
Suctioning is potentially an harmful procedure 
if carriedout improperly. 
Suctioning should be done when clinically 
necessary (not routinely). 
The need for suctioning should be assessed at 
least every 2hrs or more frequently as need 
arises.
• http://www.youtube.com/watch?v=bXXWNCY 
Z_N0 
143
LIMITATIONS OF METHOD 
Suctioning is potentially an harmful procedure 
if carriedout improperly. 
Suctioning should be done when clinically 
necessary (not routinely). 
The need for suctioning should be assessed at 
least every 2hrs or more frequently as need 
arises.
II- Mechanical complications 
1- Hypoventilation with atelectasis with respiratory 
acidosis or hypoxemia. 
2- Hyperventilation with hypocapnia and respiratory alkalosis 
3- Barotrauma 
a- Closed pneumothorax, 
b- Tension pneumothorax, 
c- Pneumomediastinum, 
d- Subcutaneous emphysema. 
4- Alarm “turned off” 
5- Failure of alarms or ventilator 
6- Inadequate nebulization or humidification 
7- Overheated inspired air, resulting in hyperthermia 
145
III- Physiological Complications 
1- Fluid overload with humidified air and 
sodium chloride (NaCl) retention 
2- Depressed cardiac function and 
hypotension 
3- Stress ulcers 
4- Paralytic ileus 
5- Gastric distension 
6- Starvation 
7- Dyssynchronous breathing pattern 
146
IV- Artificial Airway Complications 
A- Complications related to 
Endotracheal Tube:- 
1- Tube kinked or plugged 
2- Tracheal stenosis or tracheomalacia 
3- Mainstem intubation with contralateral (located on 
or affecting the opposite side of the 
• Lung) lung atelectasis 
5- Cuff failure 
6- Sinusitis 
7- Otitis media 
8- Laryngeal edema 
147
B- Complications related to 
Tracheostomy tube:- 
1- Acute hemorrhage at the site 
2- Air embolism 
3- Aspiration 
4- Tracheal stenosis 
5- Failure of the tracheostomy cuff 
6- Laryngeal nerve damage 
7- Obstruction of tracheostomy tube 
8- Pneumothorax 
9- Subcutaneous and mediastinal emphysema 
10- Swallowing dysfunction 
11- Tracheoesophageal fistula 
12- Infection 
14- Accidental decannulation with loss of airway 
148
Nursing care of patients on mechanical 
ventilation 
Assessment: 
1- Assess the patient 
2- Assess the artificial airway (tracheostomy 
or endotracheal tube) 
3- Assess the ventilator 
149
Nursing Interventions 
1-Maintain airway patency & oxygenation 
2- Promote comfort 
3- Maintain fluid & electrolytes balance 
4- Maintain nutritional state 
5- Maintain urinary & bowel elimination 
6- Maintain eye , mouth and cleanliness and 
integrity:- 
7- Maintain mobility/ musculoskeletal 
function:- 
150
Nursing Interventions 
8- Maintain safety:- 
9- Provide psychological support 
10- Facilitate communication 
11- Provide psychological support & 
information to family 
12- Responding to ventilator alarms 
/Troublshooting ventilator alarms 
13- Prevent nosocomial infection 
14- Documentation 
151
Responding To Alarms 
• If an alarm sounds, respond immediately because 
the problem could be serious. 
• Assess the patient first, while you silence the alarm. 
• If you can not quickly identify the problem, take the 
patient off the ventilator and ventilate him with a 
resuscitation bag connected to oxygen source until 
the physician arrives. 
• A nurse or respiratory therapist must respond to 
every ventilator alarm. 
152
• Alarms must never be ignored or 
disarmed. 
• Ventilator malfunction is a potentially 
serious problem. Nursing or respiratory 
therapists perform ventilator checks 
every 2 to 4 hours, and recurrent alarms 
may alert the clinician to the possibility 
of an equipment-related issue. 
153
• When device malfunction is suspected, 
a second person manually ventilates the 
patient while the nurse or therapist 
looks for the cause. 
• If a problem cannot be promptly 
corrected by ventilator adjustment, a 
different machine is procured so the 
ventilator in question can be taken out 
of service for analysis and repair by 
technical staff. 
154
WEANING 
155
Weaning readiness Criteria 
• Awake and alert 
• Hemodynamically stable, adequately resuscitated, 
and not requiring vasoactive support 
• Arterial blood gases (ABGs) normalized or at 
patient’s baseline 
- PaCO2 acceptable 
- PH of 7.35 – 7.45 
- PaO2 > 60 mm Hg , 
- SaO2 >92% 
- FIO2 ≤40% 
156
• Positive end-expiratory pressure (PEEP) ≤5 
cm H2O 
• F < 25 / minute 
• Vt 5 ml / kg 
• VE 5- 10 L/m (f x Vt) 
• VC > 10- 15 ml / kg 
157
• Chest x-ray reviewed for correctable factors; 
treated as indicated, 
• Major electrolytes within normal range, 
• Hematocrit >25%, 
• Core temperature >36°C and <39°C, 
• Adequate management of 
pain/anxiety/agitation, 
• Adequate analgesia/ sedation (record scores 
on flow sheet), 
• No residual neuromuscular blockade. 
158
Methods of Weaning 
1- T-piece trial, 
2- Continuous Positive Airway Pressure (CPAP) 
weaning, 
3- Synchronized Intermittent Mandatory Ventilation 
(SIMV) weaning, 
4- Pressure Support Ventilation (PSV) weaning. 
159
1- T-Piece trial 
• It consists of removing the patient from the 
ventilator and having him / her breathe 
spontaneously on a T-tube connected to oxygen 
source. 
• During T-piece weaning, periods of ventilator 
support are alternated with spontaneous breathing. 
• The goal is to progressively increase the time spent 
off the ventilator. 
160
2-Synchronized Intermittent Mandatory 
Ventilation ( SIMV) Weaning 
• SIMV is the most common method of weaning. 
• It consists of gradually decreasing the number of 
breaths delivered by the ventilator to allow the 
patient to increase number of spontaneous breaths 
161
3-Continuous Positive Airway Pressure ( CPAP) 
Weaning 
• When placed on CPAP, the patient does all the work 
of breathing without the aid of a back up rate or 
tidal volume. 
• No mandatory (ventilator-initiated) breaths are 
delivered in this mode i.e. all ventilation is 
spontaneously initiated by the patient. 
• Weaning by gradual decrease in pressure value 
162
4- Pressure Support Ventilation (PSV) Weaning 
• The patient must initiate all pressure support breaths. 
• During weaning using the PSV mode the level of pressure 
support is gradually decreased based on the patient 
maintaining an adequate tidal volume (8 to 12 mL/kg) and a 
respiratory rate of less than 25 breaths/minute. 
• PSV weaning is indicated for :- 
- Difficult to wean patients 
- Small spontaneous tidal volume. 
163
Role of nurse before weaning:- 
1- Ensure that indications for the implementation of 
Mechanical ventilation have improved 
2- Ensure that all factors that may interfere with successful 
weaning are corrected:- 
- Acid-base abnormalities 
- Fluid imbalance 
- Electrolyte abnormalities 
- Infection 
- Fever 
- Anemia 
- Hyperglycemia 
- Sleep deprivation 
164
Role of nurse before weaning:- 
3- Assess readiness for weaning 
4- Ensure that the weaning criteria / parameters are 
met. 
5- Explain the process of weaning to the patient and 
offer reassurance to the patient. 
6- Initiate weaning in the morning when the patient is 
rested. 
7- Elevate the head of the bed & Place the patient 
upright 
8- Ensure a patent airway and suction if necessary 
before a weaning trial, 
165
Role of nurse before weaning:- 
9 - Provide for rest period on ventilator for 15 – 20 
minutes after suctioning. 
10- Ensure patient’s comfort & administer 
pharmacological agents for comfort, such as 
bronchodilators or sedatives as indicated. 
11- Help the patient through some of the 
discomfort and apprehension. 
13- Evaluate and document the patient’s 
response to weaning. 
166
Role of nurse during weaning:- 
1-Wean only during the day. 
2- Remain with the patient during 
initiation of weaning. 
3- Instruct the patient to relax and breathe 
normally. 
4- Monitor the respiratory rate, vital signs, 
ABGs, diaphoresis and use of accessory 
muscles frequently. 
If signs of fatigue or respiratory distress develop. 
• Discontinue weaning trials. 
167
Signs of Weaning Intolerance Criteria 
• Diaphoresis 
• Dyspnea & Labored respiratory pattern 
• Increased anxiety ,Restlessness, Decrease in level of 
consciousness 
• Dysrhythmia,Increase or decrease in heart rate of > 
20 beats /min. or heart rate > 110b/m,Sustained 
heart rate >20% higher or lower than baseline 
168
Signs of Weaning Intolerance Criteria 
Increase or decrease in blood pressure of > 20 mm Hg 
Systolic blood pressure >180 mm Hg or <90 mm Hg 
• Increase in respiratory rate of > 10 above baseline 
or > 30 
Sustained respiratory rate greater than 35 
breaths/minute 
• Tidal volume ≤5 mL/kg, Sustained minute 
ventilation <200 mL/kg/minute 
• SaO2 < 90%, PaO2 < 60 mmHg, decrease in PH of < 
7.35. 
Increase in PaCO2 
169
Role of nurse after weaning 
1- Ensure that extubation criteria are 
met . 
2- Decanulate or extubate 
2- Documentation 
170
Noninvasive Bilateral Positive 
Airway Pressure Ventilation (BiPAP) 
• BiPAP is a noninvasive form of mechanical 
ventilation provided by means of a nasal mask or 
nasal prongs, or a full-face mask. 
• The system allows the clinician to select two levels 
of positive-pressure support: 
• An inspiratory pressure support level (referred to as 
IPAP) 
• An expiratory pressure called EPAP (PEEP/CPAP 
level). 
171
NON INVASIVE 
VENTILATION 
172
Absolute contraindications 
• Coma 
• Cardiac arrest 
• Respiratory arrest 
• Any condition requiring immediate intubation 
173
Suitable clinical conditions 
• Chronic obstructive pulmonary disease 
• Cardiogenic pulmonary edema 
• After discontinuation of mechanical 
ventilation (COPD) 
• OSP 
174
Patient interfaces 
• full face masks, 
• nasal pillows, 
• Nasal masks 
• and orofacial masks 
175
Ventilators 
• Usual ventilators for invasive ventilation 
• Special noninvasive ventilators 
• Modes of ventilation 
• CPAP 
• BiPAP 
176
Top 10 care essentials for ventilator 
patients 
• Review communications. 
• Check ventilator settings and modes. 
• Suction appropriately. 
• Assess pain and sedation needs. 
• Prevent infection. 
177
Top 10 care essentials for ventilator 
patients 
• Prevent hemodynamic instability. 
• Manage the airway. 
• Meet the patient’s nutritional needs. 
• Wean the patient from the ventilator 
appropriately. 
• Educate the patient and family. 
178
179

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Mechanical ventilation ppt

  • 1. NURSING MANAGEMENT OF MECHANICALLY VENTILATED PATIENTS Presented By Bibini Baby 2nd year MSc. Nsg Govt. College of Nsg Kottayam 1
  • 2. Spontaneous respiration vs. Mechanical ventilation • Natural Breathing – Negative inspiratory force – Air pulled into lungs • Mechanical Ventilation – Positive inspiratory pressure – Air pushed into lungs 2
  • 3. Mechanical ventilation • Negative pressure • Positive pressure  Invasive  Noninvasive 3
  • 4. Negative-Pressure Ventilators • Early negative-pressure ventilators were known as “iron lungs.” • The patient’s body was encased in an iron cylinder and negative pressure was generated • The iron lung are still occasionally used today. 4
  • 5. 5
  • 6. • Intermittent short-term negative-pressure ventilation is sometimes used in patients with chronic diseases. • The use of negative-pressure ventilators is restricted in clinical practice, however, because they limit positioning and movement and they lack adaptability to large or small body torsos (chests) . • Our focus will be on the positive-pressure ventilators. 6
  • 8. Initiation of Mechanical Ventilation • Indications – Indications for Ventilatory Support –Acute Respiratory Failure –Prophylactic Ventilatory Support –Hyperventilation Therapy 8
  • 9. Initiation of Mechanical Ventilation • Indications – Acute Respiratory Failure (ARF) • Hypoxic lung failure (Type I) – Ventilation/perfusion mismatch – Diffusion defect – Right-to-left shunt – Alveolar hypoventilation – Decreased inspired oxygen – Acute life-threatening or vital organ-threatening tissue hypoxia 9
  • 10. Initiation of Mechanical Ventilation • Indications – Acute Respiratory Failure (ARF) • Acute Hypercapnic Respiratory Failure (Type II) – CNS Disorders Âť Reduced Drive To Breathe: depressant drugs, brain or brainstem lesions (stroke, trauma, tumors), hypothyroidism Âť Increased Drive to Breathe: increased metabolic rate (CO2 production), metabolic acidosis, anxiety associated with dyspnea 10
  • 11. Initiation of Mechanical Ventilation • Indications – Acute Respiratory Failure (ARF) • Acute Hypercapnic Respiratory Failure (Type II) – Neuromuscular Disorders Âť Paralytic Disorders: Myasthenia Gravis, Guillain- Barre´11, poliomyelitis, etc. Âť Paralytic Drugs: Curare, nerve gas, succinylcholine, insecticides Âť Drugs that affect neuromuscular transmission; calcium channel blockers, long-term adenocorticosteroids, etc. Âť Impaired Muscle Function: electrolyte imbalance, malnutrition, chronic pulmonary disease, etc. 11
  • 12. Initiation of Mechanical Ventilation • Indications – Acute Respiratory Failure (ARF) • Acute Hypercapnic Respiratory Failure – Increased Work of Breathing Âť Pleural Occupying Lesions: pleural effusions, hemothorax, empyema, pneumothorax Âť Chest Wall Deformities: flail chest, kyphoscoliosis, obesity Âť Increased Airway Resistance: secretions, mucosal edema, bronchoconstriction, foreign body Âť Lung Tissue Involvement: interstitial pulmonary fibrotic diseases 12
  • 13. Initiation of Mechanical Ventilation • Indications – Acute Respiratory Failure (ARF) • Acute Hypercapnic Respiratory Failure – Increased Work of Breathing (cont.) Âť Lung Tissue Involvement: interstitial pulmonary fibrotic diseases, aspiration, ARDS, cardiogenic PE, drug induced PE Âť Pulmonary Vascular Problems: pulmonary thromboembolism, pulmonary vascular damage Âť Dynamic Hyperinflation (air trapping) Âť Postoperative Pulmonary Complications 13
  • 14. Initiation of Mechanical Ventilation • Prophylactic Ventilatory Support – Clinical conditions in which there is a high risk of future respiratory failure • Examples: Brain injury, heart muscle injury, major surgery, prolonged shock, smoke injury • Ventilatory support is instituted to: –Decrease the WOB –Minimize O2 consumption and hypoxemia –Reduce cardiopulmonary stress –Control airway with sedation 14
  • 15. Initiation of Mechanical Ventilation • Hyperventilation Therapy – Ventilatory support is instituted to control and manipulate PaCO2 to lower than normal levels • Acute head injury 15
  • 16. Criteria for institution of ventilatory support: Normal range Ventilation indicated Parameters 10-20 5-7 65-75 75-100 > 35 < 5 < 15 <-20 A- Pulmonary function studies: • Respiratory rate (breaths/min). • Tidal volume (ml/kg body wt) • Vital capacity (ml/kg body wt) • Maximum Inspiratory Force (cm HO2) 16
  • 17. Criteria for institution of ventilatory support: Normal range Ventilation indicated Parameters 7.35-7.45 75-100 35-45 < 7.25 < 60 > 50 B- Arterial blood Gases • PH • PaO2 (mmHg) • PaCO2 (mmHg) 17
  • 18. Initiation of Mechanical Ventilation • Contraindications – Untreated pneumothorax • Relative Contraindications – Patient’s informed consent – Medical futility – Reduction or termination of patient pain and suffering 18
  • 19. Essential components in mechanical ventilation • Patient • Artificial airway • Ventilator circuit • Mechanical ventilator • A/c or D/c power source • O2 cylinder or central oxygen supply 19
  • 20. Artificial airways • Tracheal intubation – Nasal – Oral • Supraglottic airway • Cricothyrotomy • Tracheostomy 20
  • 22. Intubation Procedure Check and Assemble Equipment: Oxygen flowmeter and O2 tubing Suction apparatus and tubing Suction catheter Ambu bag and mask Laryngoscope with assorted blades 3 sizes of ET tubes Stillet Stethoscope Tape Syringe Sterile gloves
  • 23. Intubation Procedure Position your patient into the sniffing position
  • 24. Intubation Procedure Preoxygenate with 100% oxygen to provide apneic or distressed patient with reserve while attempting to intubate. Do not allow more than 30 seconds to any intubation attempt. If intubation is unsuccessful, ventilate with 100% oxygen for 3-5 minutes before a reattempt.
  • 26. Intubation Procedure After displacing the epiglottis insert the ETT. The depth of the tube for a male patient on average is 21-23 cm at teeth The depth of the tube on average for a female patient is 19-21 at teeth.
  • 27. Intubation Procedure Confirm tube position: By auscultation of the chest Bilateral chest rise Tube location at teeth CO2 detector – (esophageal detection device or by capnography)
  • 29. Ventilator circuit • Breathing System Plain • Breathing System with Single Water Trap • Breathing System with Double Water Trap. • Breathing Filters HME Filter • Flexible Catheter Mount 29
  • 30. 30 Ventilator circuit Breathing system plain
  • 31. 31 Ventilator Breathing System (1.6m)
  • 32. 32 Ventilator Breathing System (1.6m)
  • 33. heat & moisture exchanger HME filter 33
  • 34. 34
  • 35. MECHANICAL VENTILATOR • A mechanical ventilator is a machine that generates a controlled flow of gas into a patient’s airways. Oxygen and air are received from cylinders or wall outlets, the gas is pressure reduced and blended according to the prescribed inspired oxygen tension (FiO2), accumulated in a receptacle within the machine, and delivered to the patient using one of many available modes of ventilation. 35
  • 36. Types of Mechanical ventilators • Transport ventilators • Intensive-care ventilators • Neonatal ventilators • Positive airway pressure ventilators for NIV 36
  • 37. Classification of positive-pressure ventilators • Ventilators are classified according to how the inspiratory phase ends. The factor which terminates the inspiratory cycle reflects the machine type. • They are classified as: 1- Pressure cycled ventilator 2- Volume cycled ventilator 3- Time cycled ventilator 37
  • 38. 1- Volume-cycled ventilator • Inspiration is terminated after a preset tidal volume has been delivered by the ventilator. • The ventilator delivers a preset tidal volume (VT), and inspiration stops when the preset tidal volume is achieved. 38
  • 39. 2- Pressure-cycled ventilator • In which inspiration is terminated when a specific airway pressure has been reached. • The ventilator delivers a preset pressure; once this pressure is achieved, end inspiration occurs. 39
  • 40. 3- Time-cycled ventilator • In which inspiration is terminated when a preset inspiratory time, has elapsed. • Time cycled machines are not used in adult critical care settings. They are used in pediatric intensive care areas. 40
  • 41. Mechanical Ventilators Different Types of Ventilators Available: Will depend on your place of employment Ventilators in use in MCH Servo S by Maquet Savina by Drager
  • 42. 42
  • 43. 43
  • 45. Ventilator mode • The way the machine ventilates the patient • How much the patient will participate in his own ventilatory pattern. • Each mode is different in determining how much work of breathing the patient has to do. 45
  • 46. A- Volume Modes • 1. CMV or CV • 2. AMV or AV • 3. IMV • 4. SIMV 46
  • 47. B- Pressure Modes 1- Pressure-controlled ventilation (PCV) 2- Pressure-support ventilation (PSV) 3- Continuous positive airway pressure (CPAP) 4- Positive end expiratory pressure (PEEP) 5- Noninvasive bilevel positive airway pressure ventilation (BiPAP) 47
  • 48. Control Mode Delivers pre-set volumes at a pre-set rate and a pre-set flow rate. The patient CANNOT generate spontaneous breaths, volumes, or flow rates in this mode.
  • 50. Assist/Control Mode •Delivers pre-set volumes at a pre-set rate and a pre-set flow rate. •The patient CANNOT generate spontaneous volumes, or flow rates in this mode. •Each patient generated respiratory effort over and above the set rate are delivered at the set volume and flow rate.
  • 51. Assist Control • Volume or Pressure control mode • Parameters to set: – Volume or pressure – Rate – I – time – FiO2 51
  • 52. Assist Control • Machine breaths: – Delivers the set volume or pressure • Patient’s spontaneous breath: – Ventilator delivers full set volume or pressure & I-time • Mode of ventilation provides the most support 52
  • 53. Negative deflection, triggering assisted breath Assist Control
  • 54. SYCHRONIZED INTERMITTENT MANDATORY VENTILATION (SIMV): Delivers a pre-set number of breaths at a set volume and flow rate. Allows the patient to generate spontaneous breaths, volumes, and flow rates between the set breaths. Detects a patient’s spontaneous breath attempt and doesn’t initiate a ventilatory breath – prevents breath stacking
  • 55. SIMV Synchronized intermittent mandatory ventilation • Machine breaths: – Delivers the set volume or pressure • Patient’s spontaneous breath: – Set pressure support delivered • Mode of ventilation provides moderate amount of support • Works well as weaning mode 55
  • 56. SIMV cont. 56 Machine Breaths Spontaneous Breaths
  • 57. IMV 57 Ingento EP & Drazen J: Mechanical Ventilators, in Hall JB, Scmidt GA, & Wood LDH(eds.): Principles of Critical Care
  • 59. PRESSURE REGULATED VOLUME CONTROL (PRVC): • This is a volume targeted, pressure limited mode. (available in SIMV or AC) • Each breath is delivered at a set volume with a variable flow rate and an absolute pressure limit. • The vent delivers this pre-set volume at the LOWEST required peak pressure and adjust with each breath. 59
  • 60. PRVC (Pressure regulated volume control) A control mode, which delivers a set tidal volume with each breath at the lowest possible peak pressure. Delivers the breath with a decelerating flow pattern that is thought to be less injurious to the lung…… “the guided hand”. 60
  • 61. PRCV: Advantages Decelerating inspiratory flow pattern Pressure automatically adjusted for changes in compliance and resistance within a set range Tidal volume guaranteed Limits volutrauma Prevents hypoventilation 61
  • 62. PRVC: Disadvantages Pressure delivered is dependent on tidal volume achieved on last breath Intermittent patient effort  variable tidal volumes Volume Flow Pressure Set tidal volume 62 Š Charles Gomersall 2003
  • 63. PRVC: Disadvantages Pressure delivered is dependent on tidal volume achieved on Volume Flow Pressure last breath Intermittent patient effort  variable tidal volumes Set tidal volume 63 Š Charles Gomersall 2003
  • 65. POSITIVE END EXPIRATORY PRESSURE (PEEP): • This is NOT a specific mode, but is rather an adjunct to any of the vent modes. • PEEP is the amount of pressure remaining in the lung at the END of the expiratory phase. • Utilized to keep otherwise collapsing lung units open while hopefully also improving oxygenation. • Usually, 5-10 cmH2O 65
  • 66. 66
  • 67. Pplat • Measured by occluding the ventilator 3-5 sec at the end of inspiration • Should not exceed 30 cmH2O 67
  • 68. Peak Pressure (Ppeak) • Ppeak = Pplat + Pres Where Pres reflects the resistive element of the respiratory system (ET tube and airway) 68
  • 69. Ppeak • Pressure measured at the end of inspiration • Should not exceed 50cmH2O? 69
  • 70. Auto-PEEP or Intrinsic PEEP – Normally, at end expiration, the lung volume is equal to the FRC – When PEEPi occurs, the lung volume at end expiration is greater than the FRC 70
  • 71. Auto-PEEP or Intrinsic PEEP • Why does hyperinflation occur? – Airflow limitation because of dynamic collapse – No time to expire all the lung volume (high RR or Vt) – Decreased Expiratory muscle activity – Lesions that increase expiratory resistance 71
  • 72. Auto-PEEP or Intrinsic PEEP • Adverse effects: – Predisposes to barotrauma – Predisposes hemodynamic compromises – Diminishes the efficiency of the force generated by respiratory muscles – Augments the work of breathing – Augments the effort to trigger the ventilator 72
  • 73. • This is a mode and simply means that a pre-set pressure is present in the circuit and lungs throughout both the inspiratory and expiratory phases of the breath. • CPAP serves to keep alveoli from collapsing, resulting in better oxygenation and less WOB. • The CPAP mode is very commonly used as a mode to evaluate the patients readiness for extubation. 73 Continuous Positive Airway Pressure (CPAP):
  • 74. Combination “Dual Control” Modes Combination or “dual control” modes combine features of pressure and volume targeting to accomplish ventilatory objectives which might remain unmet by either used independently. Combination modes are pressure targeted Partial support is generally provided by pressure support Full support is provided by Pressure Control 74
  • 75. Combination “Dual Control” Modes Volume Assured Pressure Support (Pressure Augmentation) Volume Support (Variable Pressure Support) Pressure Regulated Volume Control (Variable Pressure Control, or Autoflow) Airway Pressure Release (Bi-Level, Bi-PAP) 75
  • 76. • Inverse ratio ventilation (IRV) mode reverses this ratio so that inspiratory time is equal to, or longer than, expiratory time (1:1 to 4:1). • Inverse I:E ratios are used in conjunction with pressure control to improve oxygenation by expanding stiff alveoli by using longer distending times, thereby providing more opportunity for gas exchange and preventing alveolar collapse. 76
  • 77. • As expiratory time is decreased, one must monitor for the development of hyperinflation or auto-PEEP. Regional alveolar overdistension and barotrauma may occur owing to excessive total PEEP. • When the PCV mode is used, the mean airway and intrathoracic pressures rise, potentially resulting in a decrease in cardiac output and oxygen delivery. Therefore, the patient’s hemodynamic status must be monitored closely. • Used to limit plateau pressures that can cause barotrauma & Severe ARDS 77
  • 79. HIFI - Theory • Resonant frequency phenomena: – Lungs have a natural resonant frequency – Outside force used to overcome airway resistance • Use of high velocity inspiratory gas flow: reduction of effective dead space • Increased bulk flow: secondary to active expiration 79
  • 80. HIFI - Advantages • Advantages: – Decreased barotrauma / volutrauma: reduced swings in pressure and volume – Improve V/Q matching: secondary to different flow delivery characteristics • Disadvantages: – Greater potential of air trapping – Hemodynamic compromise – Physical airway damage: necrotizing tracheobronchitis – Difficult to suction – Often require paralysis 80
  • 81. HIFI – Clinical Application • Adjustable Parameters – Mean Airway Pressure: usually set 2-4 higher than MAP on conventional ventilator – Amplitude: monitor chest rise – Hertz: number of cycles per second – FiO2 – I-time: usually set at 33% 81
  • 82. Comparison of HFOV & Conventional Ventilation Differences CMV HFOV Rates 0 - 150 180 - 900 Tidal Volume 4 - 20 ml/kg 0.1 - 3 ml/kg Alveolar Press 0 - > 50 cmH2O 0.1 - 5 cmH2O End Exp Volume Low Normalized Gas Flow Low High 82
  • 83. Video on HFOV http://youtube.com/watch?v=jLroOPoPlig 83
  • 84. INITIAL SETTINGS 84 • Select your mode of ventilation • Set sensitivity at Flow trigger mode • Set Tidal Volume • Set Rate • Set Inspiratory Flow (if necessary) • Set PEEP • Set Pressure Limit • Inspiratory time • Fraction of inspired oxygen
  • 85. Trigger  There are two ways to initiate a ventilator-delivered breath: pressure triggering or flow-by triggering  When pressure triggering is used, a ventilator-delivered breath is initiated if the demand valve senses a negative airway pressure deflection (generated by the patient trying to initiate a breath) greater than the trigger sensitivity.  When flow-by triggering is used, a continuous flow of gas through the ventilator circuit is monitored. A ventilator-delivered breath is initiated when the return flow is less than the delivered flow, a consequence of the patient's effort to initiate a breath 85
  • 86. Post Initial Settings 86 • Obtain an ABG (arterial blood gas) about 30 minutes after you set your patient up on the ventilator. • An ABG will give you information about any changes that may need to be made to keep the patient’s oxygenation and ventilation status within a physiological range.
  • 87. ABG 87 • Goal: • Keep patient’s acid/base balance within normal range: • pH 7.35 – 7.45 • PCO2 35-45 mmHg • PO2 80-100 mmHg
  • 88. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Tidal Volume • Spontaneous VT for an adult is 5 – 7 ml/kg of IBW Determining VT for Ventilated Patients • A range of 6 – 12 ml/kg IBW is used for adults – 10 – 12 ml/kg IBW (normal lung function) – 8 – 10 ml/kg IBW (obstructive lung disease) – 6 – 8 ml/kg IBW (ARDS) – can be as low as 4 ml/kg • A range of 5 – 10 ml/kg IBW is used for infants and children 88
  • 89. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Respiratory Rate • Normal respiratory rate is 12-18 breaths/min. • A range of 8 – 12 breaths per minute (BPM) Rates should be adjusted to try and minimize auto- PEEP 89
  • 90. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Minute Ventilation • Respiratory rate is chosen in conjunction with tidal volume to provide an acceptable minute ventilation = VT x f • Normal minute ventilation is 5-10 L/min • Estimated by using 100 mL/kg IBW • ABG needed to assess effectiveness of initial settings – If PaCO2 >45 ( minute ventilation via f or VT) – If PaCO2 <35 ( minute ventilation via f or VT) 90
  • 91. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Inspiratory Flow • Rate of Gas Flow – As a beginning point, flow is normal set to deliver inspiration in about 1 second (range 0.8 to 1.2 sec.), producing an I:E ratio of approximately 1:2 or less (usually about 1:4) – This can be achieved with an initial peak flow of about 60 L/min (range of 40 to 80 L/min) Most importantly, flows are set to meet a patient’s inspiratory demand 91
  • 92. Expiratory Flow Pattern 92 Inspiration Expiration Time (sec) Flow (L/min) Beginning of expiration exhalation valve opens Peak Expiratory Flow Rate PEFR Duration of expiratory flow Expiratory time TE
  • 93. Initiation of Mechanical Ventilation – Flow Patterns • Selection of flow pattern and flow rate may depend on the patient’s lung condition, e.g., – Post – operative patient recovering from anesthesia may have very modest flow demands – Young adult with pneumonia and a strong hypoxemic drive would have very strong flow demands – Normal lungs: Not of key importance 93
  • 94. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Flow Pattern • Constant Flow (rectangular or square waveform) – Generally provides the shortest TI – Some clinician choose to use a constant (square) flow pattern initially because it enables them to obtain baseline measurements of lung compliance and airway resistance 94
  • 95. Initiation of Mechanical Ventilation – Flow Pattern • Sine Flow – May contribute to a more even distribution of gas in the lungs – Peak pressures and mean airway pressure are about the same for sine and square wave patterns 95
  • 96. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Flow Pattern • Descending (decelerating) Ramp – Improves distribution of ventilation, results in a longer TI, decreased peak pressure, and increased mean airway pressure (which increases oxygenation) 96
  • 97. Initiation of Mechanical Ventilation • Initial Ventilator Settings – Positive End Expiratory Pressure (PEEP) • Initially set at 3 – 5 cm H2O – Restores FRC and physiological PEEP that existed prior to intubation – Subsequent changes are based on ABG results • Useful to treat refractory hypoxemia • Contraindications for therapeutic PEEP (>5 cm H2O) – Hypotension – Elevated ICP – Uncontrolled pneumothorax 97
  • 98. Initiation of Mechanical Ventilation • Initial Ventilator Settings – FiO2 • Initially 100% – Severe hypoxemia – Abnormal cardiopulmonary functions Âť Post-resuscitation Âť Smoke inhalation Âť ARDS • After stabilization, attempt to keep FiO2 <50% – Avoids oxygen-induced lung injuries Âť Absorption atelectasis Âť Oxygen toxicity 98
  • 99. Initiation of Mechanical Ventilation – FiO2 of 40% or Same FiO2 prior to mechanical ventilation • Patients with mild hypoxemia or normal cardiopulmonary function –Drug overdose –Uncomplicated postoperative recovery 99
  • 100. Initiation of Mechanical Ventilation • Initial Ventilator Settings For PCV – Rate, TI, and I:E ratio are set in PCV as they are in Volume mode – The pressure gradient (PIP-PEEP) is adjusted to establish volume delivery Remember: Volume delivery changes as lung characteristics change and can vary breath to breath 100
  • 101. Initiation of Mechanical Ventilation • Initial Ventilator Settings For PCV – Flow Pattern • PCV provides a descending ramp waveform Note: The patient can vary the inspiratory flow on demand 101
  • 102. Initiation of Mechanical Ventilation • Initial Ventilator Settings For PCV – Rise Time (slope, flow acceleration) • Rise time is the amount of TI it takes for the ventilator to reach the set pressure at the beginning of inspiration • Inspiratory flow delivery during PCV can be adjusted with an inspiratory rise time control • Ventilator graphics can be used to set the rise time 102
  • 103. ● Sigh • A deep breath. • A breath that has a greater volume than the tidal volume. • It provides hyperinflation and prevents atelectasis. • Sigh volume :------------------Usual volume is 1.5 –2 times tidal volume. • Sigh rate/ frequency :---------Usual rate is 4 to 8 times per hour. 103
  • 104. Ensuring humidification and thermoregulation • All air delivered by the ventilator passes through the water in the humidifier, where it is warmed and saturated or through an HME filter • Humidifier temperatures should be kept close to body temperature 35 ÂşC- 37ÂşC. • In some rare instances (severe hypothermia), the air temperatures can be increased. • The humidifier should be checked for adequate water levels 104
  • 105. Initiation of Mechanical Ventilation • Ventilator Alarm Settings – High Minute Ventilation • Set at 2 L/min or 10%-15% above baseline minute ventilation – Patient is becoming tachypneic (respiratory distress) – High Respiratory Rate Alarm • Set 10 – 15 BPM over observed respiratory rate – Patient is becoming tachypneic (respiratory distress) 105
  • 106. Initiation of Mechanical Ventilation • Ventilator Alarm Settings – Low Exhaled Tidal Volume Alarm • Set 100 ml or 10%-15% lower than expired mechanical tidal volume • Causes – System leak – Circuit disconnection – ET Tube cuff leak 106
  • 107. Initiation of Mechanical Ventilation • Ventilator Alarm Settings – High Inspiratory Pressure Alarm • Set 10 – 15 cm H2O above PIP • Common causes: –Water in circuit – Kinking or biting of ET Tube – Secretions in the airway – Bronchospasm – Tension pneumothorax – Decrease in lung compliance – Increase in airway resistance – Coughing 107
  • 108. Initiation of Mechanical Ventilation • Ventilator Alarm Settings – Low Inspiratory Pressure Alarm • Set 10 – 15 cm H2O below observed PIP • Causes – System leak – Circuit disconnection – ET Tube cuff leak – High/Low PEEP/CPAP Alarm (baseline alarm) • High: Set 3-5 cm H2O above PEEP – Circuit or exhalation manifold obstruction – Auto – PEEP • Low: Set 2-5 cm H2O below PEEP – Circuit disconnect 108
  • 109. Initiation of Mechanical Ventilation • Ventilator Alarm Settings – High/Low FiO2 Alarm • High: 5% over the analyzed FiO2 • Low: 5% below the analyzed FiO2 – High/Low Temperature Alarm • Heated humidification – High: No higher than 37 C – Low: No lower than 30 C 109
  • 110. Initiation of Mechanical Ventilation • Ventilator Alarm Settings – Apnea Alarm • Set with a 15 – 20 second time delay • In some ventilators, this triggers an apnea ventilation mode – Apnea Ventilation Settings • Provide full ventilatory support if the patient become apneic • VT 8 – 12 mL/kg ideal body weight • Rate 10 – 12 breaths/min • FiO2 100% 110
  • 112. Trouble Shooting the Vent • Common problems – High peak pressures – Patient with COPD – Ventilator asynchrony – ARDS 112
  • 113. Trouble Shooting the Vent • If peak pressures are increasing: – Check plateau pressures by allowing for an inspiratory pause (this gives you the pressure in the lung itself without the addition of resistance) – If peak pressures are high and plateau pressures are low then you have an obstruction – If both peak pressures and plateau pressures are high then you have a lung compliance issue 113
  • 114. Trouble Shooting the Vent • High peak pressure differential: 114 High Peak Pressures Low Plateau Pressures High Peak Pressures High Plateau Pressures Mucus Plug ARDS Bronchospasm Pulmonary Edema ET tube blockage Pneumothorax Biting ET tube migration to a single bronchus Effusion
  • 115. COPD • If you have a patient with history of COPD/asthma with worsening oxygen saturation and increasing hypercapnia differential includes: – Must be concern with breath stacking or auto- PEEP – Low VT with increased exhalation time is advisable • Baseline ABGs reflect an elevated PaCO2 should not hyperventilated. Instead, the goal should be restoration of the baseline PaCO2. • These patients usually have a large carbonic acid load, and lowering their carbon dioxide levels rapidly may result in seizures. 115
  • 116. COPD and Asthma • Goals: – Diminish dynamic hyperinflation – Diminish work of breathing – Controlled hypoventilation (permissive hypercapnia) 116
  • 117. Trouble Shooting the Vent • Increase in patient agitation and dis-synchrony on the ventilator: – Could be secondary to overall discomfort • Increase sedation – Could be secondary to feelings of air hunger • Options include increasing tidal volume, increasing flow rate, adjusting I:E ratio, increasing sedation 117
  • 118. Trouble shooting the vent • If you are concern for acute respiratory distress syndrome (ARDS) – Correlate clinically with radiologic findings of diffuse patchy infiltrate on CXR – Obtain a PaO2/FiO2 ratio (if < 200 likely ARDS) – Begin ARDSnet protocol: • Low tidal volumes • Increase PEEP rather than FiO2 • Consider increasing sedation to promote synchrony with ventilator 118
  • 119. Accidental Extubation • Role of the Nurse: – Ensure the Ambu bag is attached to the oxygen flowmeter and it is on! – Attach the face mask to the Ambu bag and after ensuring a good seal on the patient’s face; supply the patient with ventilation. 119
  • 120. Pulmonary Disease: Obstructive Airway obstruction causing increase resistance to airflow: e.g. asthma • Optimize expiratory time by minimizing minute ventilation • Bag slowly after intubation • Don’t increase ventilator rate for increased CO2 120
  • 121. Pulmonary Disease: Restrictive Compromised lung volume: – Intrinsic lung disease – External compression of lung • Recruit alveolia, optimize V/Q matching • Lung protective strategies – High PEEP – Pressure limiting PIP: 30-35 cmH2O – Low tidal volume: 4-8 ml/kg – FiO2 <60% – Permissive hypercarbia – Permissive hypoxia 121
  • 122. In a patient with head injury, • Respiratory alkalosis may be required to promote cerebral vasoconstriction, with a resultant decrease in ICP. • In this case, the tidal volume and respiratory rate are increased ( hyperventilation) to achieve the desired alkalotic pH by manipulating the PaCO2. 122
  • 123. Complications of Mechanical Ventilation:- I- Airway Complications, II- Mechanical complications, III- Physiological Complications, IV- Artificial Airway Complications. 123
  • 124. I- Airway Complications 1- Aspiration 2- Decreased clearance of secretions 3- Nosocomial or ventilator-acquired pneumonia 124
  • 125. 125
  • 126. WHAT IS SUCTIONING?..... The patient with an artificial airway is not capable of effectively coughing, the mobilization of secretions from the trachea must be facilitated by aspiration. This is called as suctioning.
  • 127. Indications  Coarse breath sounds  Noisy breathing  Visible secretions in the airway  Decreased SpO2 in the pulse oximeter & Deterioration of arterial blood gas values  Clinically increased work of breathing  Changes in monitored flow/pressure graphics  Increased PIP; decreased Vt during ventilation
  • 128. NECESSARY EQUIPMENT  Vaccum source with adjustable regulator suction jar  stethoscope  Sterile gloves for open suctioning method  Clean gloves for closed suctioning method  Sterile catheter  Clear protective goggles, apron & mask  Sterile normal saline  Bain’s circuit or ambu bag for preoxygenate the patient  Suction tray with hot water for flushing
  • 129. TYPES OF SUCTIONING OPEN SUCTION CLOSED SUCTION
  • 130. OPEN SUCTION SYSTEM: Regularly using system in the intubated patients. CLOSED SUCTION SYSTEM:  This is used to facilitate continuous mechanical ventilation and oxygenation during the suctioning.  Closed suctioning is also indicated when PEEP level above 10cmH2O.
  • 131. Patient Preparation  Explain the procedure to the patient (If patient is concious).  The patient should receive hyper oxygenation by the delivery of 100% oxygen for >30 seconds prior to the suctioning (by increasing the FiO2 by mechanical ventilator).  Position the patient in supine position.  Auscultate the breath sounds.
  • 132. PROCEDURE Perform hand hygiene, wash hands. It reduces transmission of microorganisms. Turn on suction apparatus and set vacuum regulator to appropriate negative pressure. For adult a pressure of 100-120 mmHg, 80-100mmhg for children & 60-80mmhg for infants.
  • 133. Continue….. Goggles, mask & apron should be worn to prevent splash from secretions Preoxygenate with 100% O2 Open the end of the suction catheter package & connect it to suction tubing (If you are alone) Wear sterile gloves with sterile technique With a help of an assistant open suction catheter package & connect it to suction tubing
  • 134. Continue….. With a help of an assistant disconnect the ventilator Kink the suction tube & insert the catheter in to the ETtube until resistance is felt Resistance is felt when the catheter impacts the carina or bronchial mucosa, the suction catheter should be withdrawn 1cm out before applying suction
  • 135. Continue..... Apply continuous suction while rotating the suction catheter during removal The duration of each suctioning should be less the 15sec. Instill 3 to 5ml of sterile normal saline in to the artificial airway, if required Assistant resumes the ventilator Give four to five manual breaths with bag or ventilator
  • 136. Continue…..  Continue making suction passes, bagging patient between passes, until clear of secretions, but no more than four passes  Return patient to ventilator  Flush the catheter with hot water in the suction tray  Suction nares & oropharynx above the artificial airway  Discard used equipments  Flush the suction tube with hot water  Auscultate chest Wash hands  Document including indications for suctioning & any changes in vitals & patient’s tolerance
  • 137. Closed suctioning procedure Wash hands Wear clean gloves Connect tubing to closed suction port Pre-oxygenate the patient with 100% O2 Gently insert catheter tip into artificial airway without applying suction, stop if you met resistance or when patient starts coughing and pull back 1cm out
  • 139. Continue…..  Place the dominant thumb over the control vent of the suction port, applying continuous or intermittent suction for no more than 10 sec as you withdraw the catheter into the sterile sleeve of the closed suction device  Repeat steps above if needed  Clean suction catheter with sterile saline until clear; being careful not to instill solution into the ETtube  Suction oropharynx above the artificial airway Wash hands
  • 140. ASSESSMENT OF OUTCOME Improvement in breath sounds. Decreased peak inspiratory pressure; Increased tidal volume delivery during ventilation. Improvement in arterial blood gas values or saturation as reflected by pulse oximetry. (SpO2) Removal of pulmonary secretions.
  • 141. CONTRAINDICATIONS  Most contraindications are relative to the patient's risk of developing adverse reactions or worsening clinical condition as result of the procedure.  Suctioning is contraindicated when there is fresh bleeding.  When indicated, there is no absolute contraindication to endotracheal suctioning because the decision to abstain from suctioning in order to avoid a possible adverse reaction may, in fact, be lethal.
  • 142. LIMITATIONS OF METHOD Suctioning is potentially an harmful procedure if carriedout improperly. Suctioning should be done when clinically necessary (not routinely). The need for suctioning should be assessed at least every 2hrs or more frequently as need arises.
  • 144. LIMITATIONS OF METHOD Suctioning is potentially an harmful procedure if carriedout improperly. Suctioning should be done when clinically necessary (not routinely). The need for suctioning should be assessed at least every 2hrs or more frequently as need arises.
  • 145. II- Mechanical complications 1- Hypoventilation with atelectasis with respiratory acidosis or hypoxemia. 2- Hyperventilation with hypocapnia and respiratory alkalosis 3- Barotrauma a- Closed pneumothorax, b- Tension pneumothorax, c- Pneumomediastinum, d- Subcutaneous emphysema. 4- Alarm “turned off” 5- Failure of alarms or ventilator 6- Inadequate nebulization or humidification 7- Overheated inspired air, resulting in hyperthermia 145
  • 146. III- Physiological Complications 1- Fluid overload with humidified air and sodium chloride (NaCl) retention 2- Depressed cardiac function and hypotension 3- Stress ulcers 4- Paralytic ileus 5- Gastric distension 6- Starvation 7- Dyssynchronous breathing pattern 146
  • 147. IV- Artificial Airway Complications A- Complications related to Endotracheal Tube:- 1- Tube kinked or plugged 2- Tracheal stenosis or tracheomalacia 3- Mainstem intubation with contralateral (located on or affecting the opposite side of the • Lung) lung atelectasis 5- Cuff failure 6- Sinusitis 7- Otitis media 8- Laryngeal edema 147
  • 148. B- Complications related to Tracheostomy tube:- 1- Acute hemorrhage at the site 2- Air embolism 3- Aspiration 4- Tracheal stenosis 5- Failure of the tracheostomy cuff 6- Laryngeal nerve damage 7- Obstruction of tracheostomy tube 8- Pneumothorax 9- Subcutaneous and mediastinal emphysema 10- Swallowing dysfunction 11- Tracheoesophageal fistula 12- Infection 14- Accidental decannulation with loss of airway 148
  • 149. Nursing care of patients on mechanical ventilation Assessment: 1- Assess the patient 2- Assess the artificial airway (tracheostomy or endotracheal tube) 3- Assess the ventilator 149
  • 150. Nursing Interventions 1-Maintain airway patency & oxygenation 2- Promote comfort 3- Maintain fluid & electrolytes balance 4- Maintain nutritional state 5- Maintain urinary & bowel elimination 6- Maintain eye , mouth and cleanliness and integrity:- 7- Maintain mobility/ musculoskeletal function:- 150
  • 151. Nursing Interventions 8- Maintain safety:- 9- Provide psychological support 10- Facilitate communication 11- Provide psychological support & information to family 12- Responding to ventilator alarms /Troublshooting ventilator alarms 13- Prevent nosocomial infection 14- Documentation 151
  • 152. Responding To Alarms • If an alarm sounds, respond immediately because the problem could be serious. • Assess the patient first, while you silence the alarm. • If you can not quickly identify the problem, take the patient off the ventilator and ventilate him with a resuscitation bag connected to oxygen source until the physician arrives. • A nurse or respiratory therapist must respond to every ventilator alarm. 152
  • 153. • Alarms must never be ignored or disarmed. • Ventilator malfunction is a potentially serious problem. Nursing or respiratory therapists perform ventilator checks every 2 to 4 hours, and recurrent alarms may alert the clinician to the possibility of an equipment-related issue. 153
  • 154. • When device malfunction is suspected, a second person manually ventilates the patient while the nurse or therapist looks for the cause. • If a problem cannot be promptly corrected by ventilator adjustment, a different machine is procured so the ventilator in question can be taken out of service for analysis and repair by technical staff. 154
  • 156. Weaning readiness Criteria • Awake and alert • Hemodynamically stable, adequately resuscitated, and not requiring vasoactive support • Arterial blood gases (ABGs) normalized or at patient’s baseline - PaCO2 acceptable - PH of 7.35 – 7.45 - PaO2 > 60 mm Hg , - SaO2 >92% - FIO2 ≤40% 156
  • 157. • Positive end-expiratory pressure (PEEP) ≤5 cm H2O • F < 25 / minute • Vt 5 ml / kg • VE 5- 10 L/m (f x Vt) • VC > 10- 15 ml / kg 157
  • 158. • Chest x-ray reviewed for correctable factors; treated as indicated, • Major electrolytes within normal range, • Hematocrit >25%, • Core temperature >36°C and <39°C, • Adequate management of pain/anxiety/agitation, • Adequate analgesia/ sedation (record scores on flow sheet), • No residual neuromuscular blockade. 158
  • 159. Methods of Weaning 1- T-piece trial, 2- Continuous Positive Airway Pressure (CPAP) weaning, 3- Synchronized Intermittent Mandatory Ventilation (SIMV) weaning, 4- Pressure Support Ventilation (PSV) weaning. 159
  • 160. 1- T-Piece trial • It consists of removing the patient from the ventilator and having him / her breathe spontaneously on a T-tube connected to oxygen source. • During T-piece weaning, periods of ventilator support are alternated with spontaneous breathing. • The goal is to progressively increase the time spent off the ventilator. 160
  • 161. 2-Synchronized Intermittent Mandatory Ventilation ( SIMV) Weaning • SIMV is the most common method of weaning. • It consists of gradually decreasing the number of breaths delivered by the ventilator to allow the patient to increase number of spontaneous breaths 161
  • 162. 3-Continuous Positive Airway Pressure ( CPAP) Weaning • When placed on CPAP, the patient does all the work of breathing without the aid of a back up rate or tidal volume. • No mandatory (ventilator-initiated) breaths are delivered in this mode i.e. all ventilation is spontaneously initiated by the patient. • Weaning by gradual decrease in pressure value 162
  • 163. 4- Pressure Support Ventilation (PSV) Weaning • The patient must initiate all pressure support breaths. • During weaning using the PSV mode the level of pressure support is gradually decreased based on the patient maintaining an adequate tidal volume (8 to 12 mL/kg) and a respiratory rate of less than 25 breaths/minute. • PSV weaning is indicated for :- - Difficult to wean patients - Small spontaneous tidal volume. 163
  • 164. Role of nurse before weaning:- 1- Ensure that indications for the implementation of Mechanical ventilation have improved 2- Ensure that all factors that may interfere with successful weaning are corrected:- - Acid-base abnormalities - Fluid imbalance - Electrolyte abnormalities - Infection - Fever - Anemia - Hyperglycemia - Sleep deprivation 164
  • 165. Role of nurse before weaning:- 3- Assess readiness for weaning 4- Ensure that the weaning criteria / parameters are met. 5- Explain the process of weaning to the patient and offer reassurance to the patient. 6- Initiate weaning in the morning when the patient is rested. 7- Elevate the head of the bed & Place the patient upright 8- Ensure a patent airway and suction if necessary before a weaning trial, 165
  • 166. Role of nurse before weaning:- 9 - Provide for rest period on ventilator for 15 – 20 minutes after suctioning. 10- Ensure patient’s comfort & administer pharmacological agents for comfort, such as bronchodilators or sedatives as indicated. 11- Help the patient through some of the discomfort and apprehension. 13- Evaluate and document the patient’s response to weaning. 166
  • 167. Role of nurse during weaning:- 1-Wean only during the day. 2- Remain with the patient during initiation of weaning. 3- Instruct the patient to relax and breathe normally. 4- Monitor the respiratory rate, vital signs, ABGs, diaphoresis and use of accessory muscles frequently. If signs of fatigue or respiratory distress develop. • Discontinue weaning trials. 167
  • 168. Signs of Weaning Intolerance Criteria • Diaphoresis • Dyspnea & Labored respiratory pattern • Increased anxiety ,Restlessness, Decrease in level of consciousness • Dysrhythmia,Increase or decrease in heart rate of > 20 beats /min. or heart rate > 110b/m,Sustained heart rate >20% higher or lower than baseline 168
  • 169. Signs of Weaning Intolerance Criteria Increase or decrease in blood pressure of > 20 mm Hg Systolic blood pressure >180 mm Hg or <90 mm Hg • Increase in respiratory rate of > 10 above baseline or > 30 Sustained respiratory rate greater than 35 breaths/minute • Tidal volume ≤5 mL/kg, Sustained minute ventilation <200 mL/kg/minute • SaO2 < 90%, PaO2 < 60 mmHg, decrease in PH of < 7.35. Increase in PaCO2 169
  • 170. Role of nurse after weaning 1- Ensure that extubation criteria are met . 2- Decanulate or extubate 2- Documentation 170
  • 171. Noninvasive Bilateral Positive Airway Pressure Ventilation (BiPAP) • BiPAP is a noninvasive form of mechanical ventilation provided by means of a nasal mask or nasal prongs, or a full-face mask. • The system allows the clinician to select two levels of positive-pressure support: • An inspiratory pressure support level (referred to as IPAP) • An expiratory pressure called EPAP (PEEP/CPAP level). 171
  • 173. Absolute contraindications • Coma • Cardiac arrest • Respiratory arrest • Any condition requiring immediate intubation 173
  • 174. Suitable clinical conditions • Chronic obstructive pulmonary disease • Cardiogenic pulmonary edema • After discontinuation of mechanical ventilation (COPD) • OSP 174
  • 175. Patient interfaces • full face masks, • nasal pillows, • Nasal masks • and orofacial masks 175
  • 176. Ventilators • Usual ventilators for invasive ventilation • Special noninvasive ventilators • Modes of ventilation • CPAP • BiPAP 176
  • 177. Top 10 care essentials for ventilator patients • Review communications. • Check ventilator settings and modes. • Suction appropriately. • Assess pain and sedation needs. • Prevent infection. 177
  • 178. Top 10 care essentials for ventilator patients • Prevent hemodynamic instability. • Manage the airway. • Meet the patient’s nutritional needs. • Wean the patient from the ventilator appropriately. • Educate the patient and family. 178
  • 179. 179