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ALZHEIMER'S
DISEASE
WHAT IS ALZHEIMER’S?
   Alzheimer's is the most common form of dementia.
   It is a neurodegenerative disease that occurs in the
    brain.
    Alzheimer’s disease causes a deterioration in the brain
    by destroying the nerve cells. Once the nerve cells
    begin to deteriorate it causes a reduction of responses
    to other nerve cells.
    The condition spreads out causing chemical
    interruptions, the transmission of impulses is slow, and
    finally tissues in the brain begin to get worse.
   In Alzheimer’s disease, nerve cells in the brain die
    gradually. This makes it increasingly difficult for your
    brain’s signals to be sent properly.
   There are 7 stages of Alzheimer's
HOW YOU GET THE DISEASE?
 They still don’t know how the Alzheimer’s disease
  process begins, it seems likely that damage to the
  brain starts a decade or more before problems
  become evident.
 People who have relatives with Alzheimer’s have a
  higher risk than the general population for
  developing the disease.
 People who have a parent or sibling with
  Alzheimer's disease are 3.5 times as likely to
  develop it.
 This strong tendency of Alzheimer's disease to run
  in families is due, in part, to mutations in
  certain genes.
WHERE DOES ALZHEIMER’S AFFECT YOU IN
THE BODY?
   Alzheimer’s affects the brain.
   Alzheimer's causes neurons to die which causes the
    brain to shrink. This leads to a loss of functioning
    capabilities in almost all parts of brain, not just the ones
    that affect memory.
   This leads to the formation of clumps and tangles within
    the brain and eventually leads to death.
   When you have Alzheimer’s the cerebral cortex shrinks
    massively. The cerebral cortex is the outer surface of the
    brain and it is responsible for all intellectual functioning.
   The spaces in the folds of the brain (the sulci) are
    grossly enlarged.
   You cannot catch or spread Alzheimer’s
Normal Brain   Alzheimer’s Brain
WHEN DO YOU GET ALZHEIMER'S?
   Alzheimer’s disease can occur at any age, even as
    young as 40 years, but its occurrence is much more
    common as the years go by
   Early Alzheimer's starts at 65 years of age or younger.
    Late Alzheimer's starts after age 65
   One in ten people over 65 years of age suffer from the
    disease, and over half the people over 85 have
    Alzheimer’s disease.
   At first the symptoms are difficult to recognise.
   In the first 2 stages of Alzheimer's you cannot recognise
    that you have it.
   Often it is difficult to pinpoint when the Alzheimer’s
    disease actually began in a person.
SYMPTOMS OF ALZHEIMER'S
   Short term memory loss – forgetting recent
    events, names and places
   Difficulty performing familiar tasks
   Disorientation especially away from your normal
    surroundings
   Increasing problems with planning and managing
   Trouble with language
   Rapid, unpredictable mood swings
   Lack of motivation
   Changes in sleep and confusion about the time of day
   Reduced judgement e.g. being unaware of danger
7 STAGES OF ALZHEIMER’S
 Stage 1: Normal
 Stage 2: Normal aged forgetfulness

 Stage 3: Mild cognitive impairment

 Stage 4: Mild Alzheimer’s

 Stage 5: Moderate Alzheimer’s disease

 Stage 6: Moderately severe Alzheimer's
  disease
 Stage 7: Severe Alzheimer's disease
CURE AND TREATMENT FOR ALZHEIMER’S
 Currently there is no cure for Alzheimer’s. However
  there are several drugs that may be prescribed to
  help people with Alzheimer’s. They are not a
  cure, but can help with some of the symptoms of
  the disease.
 Drugs such as donepezil (Aricept), rivastigmine
  (Exelon), and galantamine (Reminyl) are used to
  treat symptoms in Alzheimer's disease.
 Antidepressants, anti-anxiety medications, and
  antipsychotics are used to treat the symptoms of
  depression, anxiety, agitation, and the
  hallucinations and delusions that may occur in
  Alzheimer's disease patients

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Alzheimer's disease

  • 2. WHAT IS ALZHEIMER’S?  Alzheimer's is the most common form of dementia.  It is a neurodegenerative disease that occurs in the brain.  Alzheimer’s disease causes a deterioration in the brain by destroying the nerve cells. Once the nerve cells begin to deteriorate it causes a reduction of responses to other nerve cells.  The condition spreads out causing chemical interruptions, the transmission of impulses is slow, and finally tissues in the brain begin to get worse.  In Alzheimer’s disease, nerve cells in the brain die gradually. This makes it increasingly difficult for your brain’s signals to be sent properly.  There are 7 stages of Alzheimer's
  • 3. HOW YOU GET THE DISEASE?  They still don’t know how the Alzheimer’s disease process begins, it seems likely that damage to the brain starts a decade or more before problems become evident.  People who have relatives with Alzheimer’s have a higher risk than the general population for developing the disease.  People who have a parent or sibling with Alzheimer's disease are 3.5 times as likely to develop it.  This strong tendency of Alzheimer's disease to run in families is due, in part, to mutations in certain genes.
  • 4. WHERE DOES ALZHEIMER’S AFFECT YOU IN THE BODY?  Alzheimer’s affects the brain.  Alzheimer's causes neurons to die which causes the brain to shrink. This leads to a loss of functioning capabilities in almost all parts of brain, not just the ones that affect memory.  This leads to the formation of clumps and tangles within the brain and eventually leads to death.  When you have Alzheimer’s the cerebral cortex shrinks massively. The cerebral cortex is the outer surface of the brain and it is responsible for all intellectual functioning.  The spaces in the folds of the brain (the sulci) are grossly enlarged.  You cannot catch or spread Alzheimer’s
  • 5. Normal Brain Alzheimer’s Brain
  • 6. WHEN DO YOU GET ALZHEIMER'S?  Alzheimer’s disease can occur at any age, even as young as 40 years, but its occurrence is much more common as the years go by  Early Alzheimer's starts at 65 years of age or younger. Late Alzheimer's starts after age 65  One in ten people over 65 years of age suffer from the disease, and over half the people over 85 have Alzheimer’s disease.  At first the symptoms are difficult to recognise.  In the first 2 stages of Alzheimer's you cannot recognise that you have it.  Often it is difficult to pinpoint when the Alzheimer’s disease actually began in a person.
  • 7. SYMPTOMS OF ALZHEIMER'S  Short term memory loss – forgetting recent events, names and places  Difficulty performing familiar tasks  Disorientation especially away from your normal surroundings  Increasing problems with planning and managing  Trouble with language  Rapid, unpredictable mood swings  Lack of motivation  Changes in sleep and confusion about the time of day  Reduced judgement e.g. being unaware of danger
  • 8. 7 STAGES OF ALZHEIMER’S  Stage 1: Normal  Stage 2: Normal aged forgetfulness  Stage 3: Mild cognitive impairment  Stage 4: Mild Alzheimer’s  Stage 5: Moderate Alzheimer’s disease  Stage 6: Moderately severe Alzheimer's disease  Stage 7: Severe Alzheimer's disease
  • 9. CURE AND TREATMENT FOR ALZHEIMER’S  Currently there is no cure for Alzheimer’s. However there are several drugs that may be prescribed to help people with Alzheimer’s. They are not a cure, but can help with some of the symptoms of the disease.  Drugs such as donepezil (Aricept), rivastigmine (Exelon), and galantamine (Reminyl) are used to treat symptoms in Alzheimer's disease.  Antidepressants, anti-anxiety medications, and antipsychotics are used to treat the symptoms of depression, anxiety, agitation, and the hallucinations and delusions that may occur in Alzheimer's disease patients