This document discusses the evolution of predictive operations and maintenance in the aerospace and defense industries. It argues that while disruptive digital technologies are becoming capable of enabling the industry's vision, there are still fundamental hurdles to overcome across the ecosystem, including legacy systems, siloed data and processes, and outdated skills. The document outlines a path to revolutionizing operations and maintenance through establishing a fully functioning digital thread and twin, reliable predictive analytics, optimized physical and cyber supply chains, and new decision-making organizations and skills.