Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Upcoming SlideShare
Hemophilia
Hemophilia
Loading in …3
×
1 of 14

Hemophilia

62

Share

Download to read offline

Related Books

Free with a 30 day trial from Scribd

See all

Related Audiobooks

Free with a 30 day trial from Scribd

See all

Hemophilia

  1. 1. Hemophilia A Inherited blood disease where your blood doesn’t clot normally.
  2. 2. Cause <ul><li>Lack of clotting factors </li></ul><ul><li>Hemophilia A (most common type) </li></ul><ul><ul><li>Lack of clotting factor VIII </li></ul></ul><ul><li>Passed on with X chromosome </li></ul>1
  3. 3. Symptoms <ul><li>Spontaneous bleeding </li></ul><ul><ul><li>Large or deep bruises </li></ul></ul><ul><ul><li>Joint pain and swelling - internal bleeding </li></ul></ul><ul><ul><li>Random bleeding or bruising </li></ul></ul><ul><ul><li>Blood in urine </li></ul></ul><ul><ul><li>Nosebleeds </li></ul></ul><ul><ul><li>Tightness in joints </li></ul></ul>2
  4. 4. Symptoms <ul><li>Emergency Signs </li></ul><ul><ul><li>Sudden pain, swelling, and warmth of joints and muscles </li></ul></ul><ul><ul><li>Long and painful headaches </li></ul></ul><ul><ul><li>Constant vomiting </li></ul></ul><ul><ul><li>Fatigue </li></ul></ul><ul><ul><li>Neck Pain </li></ul></ul><ul><ul><li>Double Vision </li></ul></ul>3
  5. 5. Characteristics <ul><li>Continuous bleeding after: </li></ul><ul><ul><li>Injury </li></ul></ul><ul><ul><li>Surgery </li></ul></ul><ul><ul><li>Tooth extraction </li></ul></ul>4
  6. 6. Characteristics <ul><li>More serious complications- </li></ul><ul><ul><li>Bleeding into: </li></ul></ul><ul><ul><ul><li>Joints </li></ul></ul></ul><ul><ul><ul><li>Muscles </li></ul></ul></ul><ul><ul><ul><li>Brain </li></ul></ul></ul><ul><ul><ul><li>Other internal organs </li></ul></ul></ul>5
  7. 7. Characteristics <ul><li>Lifelong Disease </li></ul>
  8. 8. Who Is Affected? <ul><li>Women may be carriers </li></ul><ul><ul><li>Passed down to children </li></ul></ul><ul><ul><ul><li>Males have 50% chance of getting disease </li></ul></ul></ul><ul><ul><ul><li>Females have 50% chance of carrying disease </li></ul></ul></ul><ul><li>Hemophilia is mostly in men </li></ul><ul><ul><li>Men only have one X-chromosome </li></ul></ul><ul><li>All age groups </li></ul><ul><ul><li>Mostly children </li></ul></ul>6
  9. 9. How It Normally Works Blood vessels are cut or damaged Clotting factor recruits collagen http://www.3dchem.com/molecules.asp?ID=195 8 7 Blood reacts to clotting factors Platelets form plug at the injury site Bleeding stops!! 11 10 9 How Disease Affects Homeostasis No clotting factor to recruit collagen No clotting factor for blood to react to Platelets don’t form a plug Bleeding Does Not Stop! 12
  10. 10. Diagnosis <ul><li>Family history of hemophilia </li></ul><ul><ul><li>Fetus testing </li></ul></ul><ul><li>Blood testing from a child or adult </li></ul><ul><li>Diagnostic Testing </li></ul><ul><li>Carrier Testing </li></ul>13
  11. 11. Treatment <ul><li>Replacement of the missing clotting factor </li></ul><ul><li>Desmopressin </li></ul><ul><ul><li>Injected into vein </li></ul></ul><ul><ul><li>Can be given as nasal medication </li></ul></ul><ul><ul><ul><li>Helps body release factor VIII </li></ul></ul></ul>14
  12. 12. Prevention <ul><li>Can’t be prevented </li></ul><ul><ul><li>Genetic disorder </li></ul></ul><ul><li>Genetic Counseling </li></ul><ul><ul><li>Figures out the chance of your child getting hemophilia </li></ul></ul><ul><li>Regular exercise </li></ul><ul><ul><li>Prevents bleeding </li></ul></ul>15
  13. 13. Bibliography - Contents <ul><li>http://www.nhlbi.nih.gov/health/dci/Diseases/hemophilia/hemophilia_what.html </li></ul><ul><li>http://www.mayoclinic.com/health/hemophilia/DS00218/DSECTION=causes </li></ul><ul><li>http://ghr.nlm.nih.gov/condition/hemophilia </li></ul><ul><li>http://www.mayoclinic.com/health/hemophilia/DS00218/DSECTION=symptoms </li></ul><ul><li>http://www.inheritedhealth.com/condition/Hemophilia/179#symptomsandcharacteristics </li></ul><ul><li>http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001565/ </li></ul><ul><li>http://www.mayoclinic.com/health/hemophilia/DS00218/DSECTION=treatments-and-drugs </li></ul><ul><li>http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/C/Clotting.html </li></ul>
  14. 14. Bibliography - Pictures <ul><li>1- http://biomed.brown.edu/Courses/BI108/2006-108websites/group01Heparin-coatedOxygenators/pages/Heparin_pharmacokinetics.htm </li></ul><ul><li>2 - http://en.nkfu.com/what-is-hemophilia-signs-and-treatment/ </li></ul><ul><li>3 - http://www.tmj.ro/article.php?art=58506380129851 </li></ul><ul><li>4 - http://www.unm.edu/~mpachman/Blood/displaz.htm </li></ul><ul><li>5 - http://www.psd202.org/PEHS/departments/science/tmurphy/sixth_hour_web/Hemophilia/symptons_and_characteristics.html </li></ul><ul><li>6 - http://presscoverage.us/soapbox/the-redefinition-of-perfect/ </li></ul><ul><li>7 - http://www.health911.com/cuts-&-wounds </li></ul><ul><li>8 - http://www.3dchem.com/molecules.asp?ID=195 </li></ul><ul><li>9 - http://www.healthjockey.com/2008/02/11/vacuming-blood-clots-proves-to-be-effective-heart-attack-treatment/ </li></ul><ul><li>10 - http://sciencephoto.com/images/download_lo_res.html?id=802600116 </li></ul><ul><li>11 - http://www.fotosearch.com/illustration/blood-drop.html </li></ul><ul><li>12 - http://www.flickr.com/photos/csessums/4966652884/ </li></ul><ul><li>13 - http://www.thereforyou.com/about-hemophilia/overview/who-gets-hemophilia.html </li></ul><ul><li>14 - http://products.hospira.com/search/productDetails?listNumber=DESMOPRESSIN_ACETATE&page=Drugs&sort=ndc&order=asc </li></ul><ul><li>15 - http://www.thereforyou.com/about-hemophilia/gist-of-genetics/genetics-counseling.html </li></ul>

×