This document provides recommendations for aspirin use for primary prevention of cardiovascular disease. It recommends aspirin for adults aged 60-69 years who have a 10-year CVD risk of 10% or higher, no increased bleeding risk, a life expectancy of at least 10 years, and a willingness to take aspirin for at least 10 years. It finds insufficient evidence for aspirin's primary prevention in adults aged 50-59 years or 70 years and older.

1. Use of Aspirin for Primary Prevention of
Cardiovascular Disease
Patient Category
Recommendation
Adults aged ≥70 years
Adults aged 60-69 years
Type to enter a caption.
Adults aged 50-59
years
Insufficient evidence for primary prevention
Aspirin recommended in patients with a 10-year CVD riska ≥10%, no
increased bleeding risk, life expectancy of ≥10 years, and willingness
to take aspirin for ≥10 years
Insufficient evidence for primary prevention