Pharmacology Review Chapter 29-38

Pharmacology Review II Chapters 28 - 38 All Materials in this presentation come from: Karch, A. (2008). Focus on: nursing pharmacology. New York, NY: Lippincott Williams & Wilkins.

Sympathetic response ,[object Object],[object Object],[object Object],[object Object],Heart pounds Hormones released Breath hard Eyes wide open

Sympathetic response ,[object Object],[object Object],[object Object],[object Object],Beta 1 receptors Alpha 2 receptors Beta 2 receptors Alpha 1 receptors (1 heart) (2 lungs)

Sympathetic response ,[object Object],[object Object],[object Object],[object Object],Alpha 1 receptors Beta 1 Receptors Alpha 2 receptors Beta 2 Receptors

Sympathetic response ,[object Object],[object Object],Alpha 1 receptors Dilate pupils Close bladder spinchter Vasoconstrict blood vessels Alpha 2 receptors Regulate norepinephrine Moderate insulin release Beta 2 receptors Dilate bronchi Breakdown glycogen Relax uterine muscle Beta 1 receptors Increase heart rate Breakdown fat for energy

Sympathetic response ,[object Object],[object Object],Alpha 1 receptors Agonists “ine” Blockers “zosin” Alpha 2 receptors Clonidine Beta 2 receptors Blockers “olols” Beta 1 receptors Blockers “olols”

Parasympathetic Response Acetylcholine responses Heart slows Digestion starts Bladder works Eyes constrict Bronchi constrict

Parasympathetic Response Muscarinic Receptors (Smooth muscle) Pupils, bladder, GI motility Heart vessels Nicotinic Receptors NMJ Muscle constractions

Heart Rate medications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Adrenergic Agonists - “ine” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],David Price “ ine” it to win it! The race against time with shock

Case Study # 1 Adrenergic Agonists ,[object Object],[object Object],[object Object]

Dopamine ,[object Object],[object Object],[object Object],Help me! I need oxygen…

Case Study # 2 Adrenergic Blockers ,[object Object],[object Object],[object Object]

Increased adrenergic efffects ,[object Object],[object Object]

Case Study # 3 Adrenergic Blockers ,[object Object],[object Object]

Adrenergic Blockers ,[object Object],[object Object],[object Object]

Alpha Adrenergic Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],That patient is not “ dozin” on the floor! Orthostatic hypotension Is a side effect of Prazosin (anti-hypertensive)

Case Study # 4 Adrenergic blockers ,[object Object],[object Object]

Adrenergic Blockers - “zosins” ,[object Object],[object Object],[object Object],Have the PSA level checked regularly

Beta Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Inderal… kick in about now!!!

Beta Blockers - “olols” ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],What’s all that “ lol” crap on the cell phone. I got all the “lols” I need For my hypertension

Beta Blockers ,[object Object],[object Object],[object Object],Apply cotton ball here to prevent Systemic effect

Case Study # 5 Beta Blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Beta blockers ,[object Object],[object Object],[object Object],[object Object],Kasey’s mom’s lungs were unable to dilate with the inflammation caused by the pollen

Beta 1 blockers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case Study # 6 Cholinergic agents ,[object Object],[object Object],[object Object],[object Object]

Cholinergics ,[object Object],[object Object],[object Object]

Case Study # 7 Indirect acting cholinergics ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pyridostigmine ,[object Object],[object Object],[object Object]

Prostigmin (neostigmine) ,[object Object],[object Object],[object Object],[object Object],[object Object],Know this!

Case Study # 8 Alzheimer’s Disease ,[object Object],[object Object]

Aricept (donepezil) ,[object Object],[object Object],[object Object],[object Object]

Anticholinergics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case Study # 9 Anticholinergics ,[object Object],[object Object]

Anticholinergics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Dries you out like a desert..

Case Study # 11 Glucocrticoids ,[object Object],[object Object]

Glucocoticoids and vaccines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case Study # 12 Glucocorticoids ,[object Object],[object Object]

Glucocorticoids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case Study # 13 ,[object Object],[object Object],[object Object],[object Object]

Thryoid function ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Hey, don’t forget us! The parafollicular cells Reduce clacium resoprtion

Thyroid function ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Treat with Levothyroxine (Synthroid) Treat with PTU (propylthiouracil)

Case Study # 14 ,[object Object],[object Object],[object Object]

Graves’ disease ,[object Object],[object Object]

Case Study # 15 Antihypercalcemic agents ,[object Object],[object Object]

Fosamax (alendronate) ,[object Object],[object Object],[object Object],[object Object]

Hyperglycemia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Watch for: Fruity breath Fatigue Irritation Itchy skin Dehydration Kussmaul’s respirations

Hypoglycemia ,[object Object],Recognize these signs: Headache Blurred vision Tachycardia Hunger, nausea Diaphoresis, cool clammy skin Patient may appear drunk !

Case Study # 16 Antidiabetic agents ,[object Object],[object Object]

HbA1c ,[object Object],[object Object],[object Object]

Case Study # 15 Antidiabetic agents ,[object Object],[object Object]

Antidiabetics ,[object Object],[object Object],[object Object]

Case Study # 16 Antidiabetic ,[object Object],[object Object],[object Object],[object Object],Breakfast

Type I Diabetes ,[object Object]

Pharmacology Review Chapter 29-38

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Pharmacology Review Chapter 29-38