Disseminated Intravascular Coagulation

Disseminated Intravascular Coagulation ,[object Object],[object Object],[object Object]

General Considerations ,[object Object],[object Object]

Classification ,[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object]

Pathophysiology ,[object Object]

Stimulation of Coagulation Intravascular thrombosis Consumption of coagulation factors Secondary activation of thrombolysis Hypoperfusion to tissues and organs Inability to form a stable clot Release of anticoagulants Ischemic damage Bleeding Bleeding

Diagnosis ,[object Object],[object Object],[object Object]

Symptoms and Signs ,[object Object],[object Object],[object Object],[object Object]

Meningococcemia Associated Purpura

Acute DIC ,[object Object],[object Object],[object Object],[object Object],[object Object]

Chronic DIC ,[object Object],[object Object],[object Object],[object Object],[object Object]

Purpura fulminans of a child's leg

Markedly decreased Protein C Markedly decreased Antithrombin III (AT III) Normal or decreased Fibrinogen Markedly increased Fibrin degradation products (FDP) Increased Activated partial thromboplastin time (APTT) Increased Prothrombin time (PT) Markedly decreased Platelet count Result Test

Different Diagnosis ,[object Object],[object Object],[object Object],[object Object]

Liver disease ,[object Object],[object Object]

Vitamin K deficiency ,[object Object]

TTP (Thrombotic thrombocytopenic purpura ) ,[object Object]

Treatment ,[object Object],[object Object],[object Object],[object Object]

Treatment of the underlying disorder ,[object Object]

Replacement therapy ,[object Object],[object Object]

Heparin therapy ,[object Object],[object Object]

Other Treatment ,[object Object],[object Object]

Acute DIC ,[object Object],[object Object],[object Object]

Chronic DIC ,[object Object],[object Object]

Complications ,[object Object],[object Object],[object Object]

Prognosis ,[object Object],[object Object]

Summary ,[object Object],[object Object]

Disseminated Intravascular Coagulation

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Disseminated Intravascular Coagulation