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CT AND MRI UROGRAPHY
DR. DEV LAKHERA
UROGRAPHY DEFINITION
 Urography is a radiologic technique used for the evaluation of the
genitourinary system: specifically, the kidneys, ureters and bladder.
UROGRAPHIC TECHNIQUES
 INTRAVENOUS UROGRAPHY
 COMPUTERIZED TOMOGRAPHIC UROGRAPHY
 MAGNETIC RESONANCE UROGRAPHY
CT urography
 Hybrid CTU
 CT Urography
Hybrid CT urography
 CT and IVU are done together.
 Adv :- no reformatting needed
 Disadv:- Imaging at different location
CTU Protocol –Three phase protocol
 Unenhanced phase
 Nephrographic phase after 90-100 secs
 Pyelographic phase after 12-15 minutes
 4 Phase protocol (5 min and 7.5 min)
Contrast media
 Omnipaque (100-150 ml non ionic contrast media at a rate of
2-4 ml/second)
Split Bolus MDCT Urography with Synchronous
Nephrographic and Excretory Phase Enhancement
 Unenhanced Phase
 Nephro-pyelographic phase : 30 ml of nonionic contrast
material is infused and after 10 min another 100 ml of
contrast is injected
 ADV: Assess tract with low radiation exposure.
Image post processing techniques
Multiplanar Reformation (MPR)
Maximum Intensity
Projection (MIP)
 Projecting the voxel with the
highest attenuation value on
every view throughout the
volume onto a 2D image
Volume rendering technique (VRT)
Indication of CT Urography
 To evaluate patients with hematuria
 Calculi
 Renal / Urothelial tumors
 Congenital anomalies.
Renal calculi
 Presence, size and location of urinary
tract calculi
 Exclude extraurinary pathologies that
may mimic calculi
Renal Tumors
 Enhancement : Nephrographic phase
 Location : Renal cell carcinoma is frequently located at the periphery or
near the cortico-medullary junction of the kidney as it originates in the
renal cortex
 tumors with nephron sparing surgery
CT urogram (volume
rendering )
Axial CECT
UROTHELIAL CARCINOMA
Excretory phase CTU shows a soft-Tissue attenuation mass in
upper left kidney with associated calyceal distortion
Coronal reformatted image MIPimage
Papillary necrosis
Ureteric injury
Congenital anomalies
 Retrocaval ureter
 Ureteral duplication
 Crossed fused kidneys
 Ectopic kidneys
Fused low lying ectopic kidney
Maximum intensity projection curved planar reformation excretory phase CT urogram
Advantages of IVU over CT urography
 Better spatial resolution
 Lesser radiation dose
 Cheaper
Ct urography: Advantages
 Multidetector CT : Thin slices in single breath hold allow optimal
anatomic information
 Isotropic MPR reconstruction
 Better contrast resolution
Image improvement techniques
 Compression
 Saline Infusion
 Diuretic Administration
 Patient Positioning
34 year old lady with pain Left side of abdomen, and
hydronephrosis on USG
MR Urography
 urinary tract obstruction
 Hematuria
 congenital anomalies
 surgically altered anatomy
beneficial in pediatric or pregnant patients or when ionizing radiation is to be
avoided
Principle
 urine have very long T2-relaxation time
 heavily T2-weighted pulse sequence generate images with high signal intensity
from static fluid
Sequences
 Without contrast administration : Heavily T2-weighted static-fluid
MR urograms
 Half fourier acquisition single-shot turbo spin-echo(HASTE
sequence)
 With contrast administration with excretory T1-weighted sequences
(excretory MRU)
Static fluid MR
Urogram
 demonstrates the collecting
system, ureters and bladder
 Coronal static-fluid MR urogram
shows obstruction of the right distal
ureter in a patient with prostrate
cancer
 Coronal single-shot fast
spin-echo image shows
a metastatic lymph node
Excretory urography
 Gadolinium shortens the T1
relaxation time of the urine,
allowing the urine to initially appear
bright on T1-weighted image
 Dose: 0.1 mmol/kg
Effect of gadolinium
excretion on T2-
weighted MR urographic
techniques
static-fluid MR urography MIP excretory urography after gadolinium
Advantages
 MRU has better contrast resolution than CT urography
 without radiation exposure and IV contrast administration
Disadvantages over CT Urography
 Longer examination times than for CT urography
 Decreased spatial resolution
 Inability to reliably depict calcifications and calculi
THANK YOU

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Ct mri urography

Editor's Notes

  1. IVU IS THE MOST COMMONLY USED TECHIQUE , CT urography is a developing diagnostic imaging technique is progressively replacing the ivu in western contries , ROLE OF MR IN UROGRPAHY IS STILL BEING ESTABLISHED
  2. Two sets of
  3. Solution: table top with insertable grid and cassette and ceiling mounted xray tube , Scanned projection radiographic
  4. (100-150 ml non ionic contrast media at a rate of 2-4 ml/second) //Nephrogenic phase is after the cortico-medullary phase (50 seconds) –dye has reached the distal part of collecting duct( renal vasculature) // To evaluate urothelium from the pelvicalyceal system to the bladder // avoided due to radiation risks
  5. Unenhanced CT scans used for the evaluation of calculi, renal parenchymal calcifications, precontrast attenuation measurements// nephrographic phase is Neoplasm inflammatory diseases
  6. (Iohexol) 300mg/min
  7. (A) Coronal MPR image demonstrating only a small segment of the left ureter in its mid portion (B) Curved multiplanar reformation displaying a left ureteric calculus, the consequent hydronephrosis and the entire dilated ureter proximal to it in a single image regardless of opacificaion
  8. area of interest can be obscured the by high density material, such as bone, calcium, and oral contrast medium.---Better detect pulmonary nodules, vessels MINip areas of emphysema
  9. all attenuation values within a voxel are used to obtain the final image Entire volume of data and displays anatomic structures with different levels of attenuation //with bone editing///angiography , large airway abnormality
  10. Symptomatic indications include hematuria,
  11. Secondary signs obstructive urinary calculi of Hydronephrosis, hydroureter, ipsilateral renal enlargement. Calculi in unusual positions such as in calyceal divertculae
  12. VRT image (B) displaying the same
  13. Enhance ment of more than 20 HU// Require information about its location near the collecting system. ….
  14. Contrast-enhanced axial CT scan: (A) showing an enhancing mass in the upper and mid pole of the right kidney. CT urogram using volume rendering (B) showing distortion of the calyces by the mass lesion
  15. CT urogram using MIP technique (C) showing splaying, distortion of the calyces on the right side –right renal cell carcinoma
  16. excretory IVU shows compression of the upper left renal infundibulum
  17. Papillary necrosis. Coronal (A) and sagittal (B) MIP images of the left kidney demonstrate a filling defect in the superiormost calyx (arrow) secondary to sloughing of the papilla into the calyx.
  18. Axial CT scan of the pelvis in the excretory phase demonstrates extravasation of contrast 3D volume-rendered image of the study shows the exact location of the ureteric injury
  19. ureteric compression but also the IVC
  20. low lying ectopic kidney with fusion of both kidneys
  21. Volume rendered image in the excretory phase
  22. Duplicated collecting system with an ureterocele///dilated left upper pole and ureter (arrows) and ureterocele
  23. Projectional imaging technique The patient's body habitus, state of bowel preparation, and renal excretion rate are factors contributing directly to the visible radiographic contrast, and can lead to sub-optimal image quality,
  24. Cross section radiography, projection radiography. compromised by variables like bowel preparation, renal function and radiographic factors. three-dimensional view of the renal morphology
  25. Furosemide: prone position achieved higher opacification of the mid and distal ureters.
  26. a) Scout film KUB area shows no radio-opaque calculus. b) 30 minutes prone IVU film showing hydronephrosis with proximal hydroureter Left side. c) CTU Coronal MIP image clearly showing calculus within Left ureter.
  27. ionizing radiation or iodinated contrast material is to be avoided.
  28. treats the urinary tract as a static column of fluid--high signal intensity from static fluid in the collecting whereas lower signal intensity from parenchymal tissue is suppressed. ..Diuretic administration…. extremely fast and are performed in one breathhold
  29. Static-fluid MR urography does not require the excretion of contrast material and is therefore useful for
  30. Prostate cancer metastatis to lymph nodes
  31. A, Coronal T2-weighted MR image shows low-signal intensity filling defect ( Arrow ) in right renal pelvis. B, T2-weighted static-fluid MR urograph confirms presence of filling defect (Arrowhead ) in renal pelvis
  32. A, Unenhanced CT urographic scan through pelvis shows thickened postpar tum uterus ( arrow).B,Pyelographic phase CT urographic scan shows multiple filling defects ( Arrowhead ) due to blood clots in bladder.
  33. C, Coronal reformation of pyelographic phase CT urographic scan shows absence of contrast excretion from right renal collecting system ( arrow).D,Coronal T2weighted static-fluid MR urograph shows filling defects (arrowhead) suggestive of blood clots in pelvicaliceal system of kidney.
  34. Coronal MIP image from excretory MR urographic data
  35. The T2 shortening effect of gadolinium prevents successful application of static-fluid MR urography during the excretory phase after the intravenous administration of gadolinium-based
  36. Static fluid mru shows the presence of urine rather than excretory function