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AORTIC
REGURGITATION

      DR.V.K.RAJAMANI
• WHAT ARE THE SYMPTOMS
  OF AORTIC REGURGITATION ?
CHRONIC SEVERE AORTIC REGURGITATION:

Asymptomatic: 10-15 Years

 *PALPITATION - early symptom
*HEAD POUNDING - on exertion

*EXERTIONAL DYSPNOEA

*ORTHOPNOEA

*PAROXYSMAL NOCTURNAL DYSPNOEA

*EXCESSIVE      DIAPHORESIS

*ANGINA         - on exertion/ at rest
                - nocturnal

*CCF   - late
• DESCRIBE THE PULSE IN
    AORTIC REGURGITATION
•Corrigan’s pulse
            or
•Water hammer pulse
            or
•Collapsing pulse

                - Rapid rise and rapid fall



•Bisferiens’s pulse -two peaks in systole
•DESCRIBE THE HEART SOUNDS IN
    AORTIC REGURGITATION
S1- may be soft due to premature closure of the
    mitral valve.

A2 –normal or accentuated when AR is due to aortic root
disease.

S2-   absent
       or single
       or exhibit narrow
       or paradoxical splitting

S3 GALLOP - due
              to increased LV end diastolic volume or
            impaired LV function

Systolic ejection sound - related to abrupt distention of the
                     aorta by the augmented stroke volume.
•DESCRIBE THE MURMURS
OF AORTIC REGURGITATION
CHRONIC AORTIC REGURGITATION
Early diastolic murmur

*High pitched, blowing decrescendo

*Best heard in the 3rd left intercostal space
               -with the patient sitting up and leaning forward
               -breath held in forced expiration
*Aortic root disorders- murmur is best heard along right sternal border
*Cooving or musical murmur- evertion or perforation of the aortic cusps
*Longer the duration of murmur severer the aortic regurgitation
*Becomes short - cardiac failure
Ejection systolic murmur- flow murmur

             - best heard at the base of the heart.
             - transmitted along the carotids.

 Austin flint murmur

  * Soft, low pitched rumbling mid diastolic
   murmur.
 * Diastolic displacement of the anterior leaflet of
   the mitral valve by the aortic regurgitation stream.
 * Auscultatory events- intensified by handgrip.
•WHAT ARE THE PERIPHERAL SIGNS
OF AORTIC REGURGITATION ?
1.Traube’s sign:

  Pistol shot sounds
               -booming systolic and diastolic sounds
                heard over the femoral arteries.

2.Muller sign:

  Systolic pulsations of the uvula.

3.Duroziez sign:

  Systolic murmur over the femoral artery, when
  compressed proximally. Diastolic murmur when
  compressed distally.
4.Quincke sign:

  capillary pulsations detected
   by pressing a glass slide on the lips or
   by transmitting a light through the patient’s fingertips or
   by exerting gentle pressure on the tip of a finger nail.

5.De Musset sign:

         Bobbing of head with each heart beat.

6.Hill sign:

     Popliteal cuff systolic pressure exceeding brachial cuff
     systolic pressure by more than 20 mmHg.
• How will you differentiate
  aortic regurgitation murmur from
    pulmonary regurgitation murmur ?
*Pulmonary regurgitation murmur is often heard in patients with
severe pulmonary hypertension. Hence it is associated with loud
P2.

*Pulmonary regurgitation murmur is better heard during
inspiration while aortic regurgitation murmur is better heard
during expiration.

*Aortic regurgitation murmur is often associated with peripheral
signs of aortic regurgitation.
•How will you distinguish
  Austin flint murmur from
Organic mitral stenosis murmur?
*Opening snap
                             In favour
*Loud first heart sound         of
                            mitral stenosis
*Loud P2 due to pulmonary
 hypertension
• What are the clinical signs of
   acute aortic regurgitation ?
•Patients with acute severe aortic regurgitation appear gravely ill
•Tachycardia
•Peripheral cyanosis
•Peripheral signs of aortic regurgitation are absent/not impressive
•Left ventricle impulse is normal
•Rocking motion of chest is absent
•Signs of pulmonary congestion/ oedema
• WHAT ARE THE CAUSES OF
   ACUTE AORTIC REGURGITATION?
•Infective endocarditis
•Prosthetic valve dysfunction
•Aortic dissection
•Trauma
•Systemic hypertension
• What are the causes of
   chronic aortic regurgitation?
*Rheumatic heart disease
*Congenital bicuspid aortic valve
*Infective endocarditis

*Aortic root dilatation

*In association with other diseases
•CONGENITAL

-VSD

-Supravalvular aortic stenosis

-Discrete subvalvular aortic stenosis

-Aneurysm of the sinus of valsalva

•CONNECTIVE TISSUE DISEASE

           * Marfan’s syndrome
          * Osteogenesis Imperfecta
          * Ehlers-danlos syndrome
•AUTO IMMUNE DISEASES

     * Ankylosing spondylitis
     * Rheumatoid arthritis
     * Systemic lupus erythematosus

•SYPHILIS

•VARIOUS FORMS OF AORTITIS OR ARTERITIS

        eg:     Giant cell arteritis
                Takayasu’s disease

•DRUGS- ANORECTIC DRUGS

              *Fenfluramine
              *Dexfenfluramine

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Aortic regurgitation

  • 1. AORTIC REGURGITATION DR.V.K.RAJAMANI
  • 2. • WHAT ARE THE SYMPTOMS OF AORTIC REGURGITATION ?
  • 3. CHRONIC SEVERE AORTIC REGURGITATION: Asymptomatic: 10-15 Years *PALPITATION - early symptom *HEAD POUNDING - on exertion *EXERTIONAL DYSPNOEA *ORTHOPNOEA *PAROXYSMAL NOCTURNAL DYSPNOEA *EXCESSIVE DIAPHORESIS *ANGINA - on exertion/ at rest - nocturnal *CCF - late
  • 4. • DESCRIBE THE PULSE IN AORTIC REGURGITATION
  • 5. •Corrigan’s pulse or •Water hammer pulse or •Collapsing pulse - Rapid rise and rapid fall •Bisferiens’s pulse -two peaks in systole
  • 6. •DESCRIBE THE HEART SOUNDS IN AORTIC REGURGITATION
  • 7. S1- may be soft due to premature closure of the mitral valve. A2 –normal or accentuated when AR is due to aortic root disease. S2- absent or single or exhibit narrow or paradoxical splitting S3 GALLOP - due to increased LV end diastolic volume or impaired LV function Systolic ejection sound - related to abrupt distention of the aorta by the augmented stroke volume.
  • 8. •DESCRIBE THE MURMURS OF AORTIC REGURGITATION
  • 9. CHRONIC AORTIC REGURGITATION Early diastolic murmur *High pitched, blowing decrescendo *Best heard in the 3rd left intercostal space -with the patient sitting up and leaning forward -breath held in forced expiration *Aortic root disorders- murmur is best heard along right sternal border *Cooving or musical murmur- evertion or perforation of the aortic cusps *Longer the duration of murmur severer the aortic regurgitation *Becomes short - cardiac failure
  • 10. Ejection systolic murmur- flow murmur - best heard at the base of the heart. - transmitted along the carotids. Austin flint murmur * Soft, low pitched rumbling mid diastolic murmur. * Diastolic displacement of the anterior leaflet of the mitral valve by the aortic regurgitation stream. * Auscultatory events- intensified by handgrip.
  • 11. •WHAT ARE THE PERIPHERAL SIGNS OF AORTIC REGURGITATION ?
  • 12. 1.Traube’s sign: Pistol shot sounds -booming systolic and diastolic sounds heard over the femoral arteries. 2.Muller sign: Systolic pulsations of the uvula. 3.Duroziez sign: Systolic murmur over the femoral artery, when compressed proximally. Diastolic murmur when compressed distally.
  • 13. 4.Quincke sign: capillary pulsations detected by pressing a glass slide on the lips or by transmitting a light through the patient’s fingertips or by exerting gentle pressure on the tip of a finger nail. 5.De Musset sign: Bobbing of head with each heart beat. 6.Hill sign: Popliteal cuff systolic pressure exceeding brachial cuff systolic pressure by more than 20 mmHg.
  • 14. • How will you differentiate aortic regurgitation murmur from pulmonary regurgitation murmur ?
  • 15. *Pulmonary regurgitation murmur is often heard in patients with severe pulmonary hypertension. Hence it is associated with loud P2. *Pulmonary regurgitation murmur is better heard during inspiration while aortic regurgitation murmur is better heard during expiration. *Aortic regurgitation murmur is often associated with peripheral signs of aortic regurgitation.
  • 16. •How will you distinguish Austin flint murmur from Organic mitral stenosis murmur?
  • 17. *Opening snap In favour *Loud first heart sound of mitral stenosis *Loud P2 due to pulmonary hypertension
  • 18. • What are the clinical signs of acute aortic regurgitation ?
  • 19. •Patients with acute severe aortic regurgitation appear gravely ill •Tachycardia •Peripheral cyanosis •Peripheral signs of aortic regurgitation are absent/not impressive •Left ventricle impulse is normal •Rocking motion of chest is absent •Signs of pulmonary congestion/ oedema
  • 20. • WHAT ARE THE CAUSES OF ACUTE AORTIC REGURGITATION?
  • 21. •Infective endocarditis •Prosthetic valve dysfunction •Aortic dissection •Trauma •Systemic hypertension
  • 22. • What are the causes of chronic aortic regurgitation?
  • 23. *Rheumatic heart disease *Congenital bicuspid aortic valve *Infective endocarditis *Aortic root dilatation *In association with other diseases
  • 24. •CONGENITAL -VSD -Supravalvular aortic stenosis -Discrete subvalvular aortic stenosis -Aneurysm of the sinus of valsalva •CONNECTIVE TISSUE DISEASE * Marfan’s syndrome * Osteogenesis Imperfecta * Ehlers-danlos syndrome
  • 25. •AUTO IMMUNE DISEASES * Ankylosing spondylitis * Rheumatoid arthritis * Systemic lupus erythematosus •SYPHILIS •VARIOUS FORMS OF AORTITIS OR ARTERITIS eg: Giant cell arteritis Takayasu’s disease •DRUGS- ANORECTIC DRUGS *Fenfluramine *Dexfenfluramine