anaesthesiology medicine icu drnb edic critical care midazolam seizures epilepsy status epilepsy vomiting ondansetron ponv first order kinetics pharmacology pharmacokinetics half life volume of distribution pringle manuever liver resection livertransplant hepatectomy hepatobiliary surgey tof pda vsd chd paediatric anaesthesia asd pneumoperitoneum laparoscopy gasless laparoscopy dnb inotropes anaesthesia
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