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- 14. RISK ==== 5% (advance CKD) Danish Med Agency. 2006
- 21. Sufficiently deep biopsies show increased numbers of fibroblast-like cells in the dermis, extending into the fascia along subcutaneous septa.
- 22. The dermis demonstrates haphazardly arranged collagen bundles and a strikingly increased number of spindled and plump fibroblast-like cells
- 23. The spindled and plump fibroblast-like cells extend into the fascia along subcutaneous septa.
- 24. Mucin is frequently present and demonstrable by the colloidal iron or alcian blue (pH 2.5) staining methods
- 31. Areas of thick, hardened skin, commonly associated with brawny hyperpigmentation, and preferentially localized to the extremities
- 32. Extensive thickening of the skin, often associated with brawny hyperpigmentation, and in some cases, distinct papules and subcutaneous nodules.