This document summarizes a workshop presentation about using chance events and intervention to generate hypotheses. It discusses abduction as the "logic" of hypothesis generation, where scientists generate explanations for observed facts rather than passively observing. The document also discusses how intervention through "epistemic mediation" and "tinkering on chance events" can help address Meno's Paradox that you cannot search for something without knowing what you are looking for. Chance-seeking is presented as an adaptive, forward-looking process that makes use of ignorance and chance events to generate knowledge through clumsy but workable solutions.