1. 1. A human body cools in water much C. Mature
faster that in the air. What way of heat emission D. Atretic
in water is much more efficient? E. Primary
A. Convection 7. 2 hours after a skeletal extension was
B. Heat radiation performed to a 27 year old patient with
C. Heat conduction multiple traumas (closed injury of chest
D. Sweat evaporation closed fracture of right thigh) his condition
E. - abruptly became worse and the patient died
2. A driver who got a trauma in a road accident from acute cardiopulmonary decompensation.
and is shocked has reduction of daily Histological examination of pulmonary
urinary output down to 300 m1. What is the and cerebral vessels stained with Sudan III
main pathogenetic factor of such diuresis revealed orange drops occluding the vessel
change? lumen. What complication of polytrauma
A. Drop of arterial pressure. was developed?
B. Secondary hyperaldosteronism A. Air embolism
C. Increased vascular permeability B. Thromboembolism
D. Decreased number of functioning C. Fat embolism
glomerules D. Microbal embolism
E. Drop of oncotic blood pressure E. Gaseous embolism
3. Myocyte cytoplasm contains a big number 8. A patient complains of frequent diarrheas,
of dissolved metabolites of glucose oxidation. especially after consumption of
Name one of them that turns directly rich food, weight loss. Laboratory examination
into a lactate: revealed steatorrhea; his feces were
A. Pyruvate hypocholic. What might have caused such
B. Glycerophosphate condition?
C. Glucose 6-phosphate A. lnflammation of mucous membrane of
D. Oxaloacetate small intestine
E. Fructose 6-phosphate B. Obturation of biliary tracts
4. Continuous taking of some drugs foregoing C. Lack of pancreatic lipase
the pregnancy increase the risk of giving D. Lack of pancreatic phospholipase
birth to a child with genetic defects. What is E. Unbalanced diet
this effect called? 9. A 12 year old child has intolerance to
A. Mutagenic effect some foodstuffs. Their consumption causes
B. Blastomogenic effect an allergic reaction in form of itching skin
C. Fetotoxical effect eruptions. What antihistaminic drug should
D. Embryotoxic effect be admistered so that the child could attend
E. Teratogenic effect school?
5. A patient has yellow skin colour, dark urine A. Loratadine
dark-yellow feces. What substance will B. Dimedrol
have strengthened concentration in the C. Ephedrine
blood scrum? D. Aminophylline
A. Verdoglobin E. Diclofenac
B. Conjugated bilirubin 10. Labelled amino acids alanine and
C. Biliverdin tryptophane were injected to a mouse
D. Unconjugated bilirubin in order to study localization of protein
E. Mesobilirubin synthesis in its cells. The labelled amino acids
6. Examination of an ovary specimen stained will be accumulated near the following
by hematoxylin-eosine revealed a follicle organellas:
in which follicular epithelium consisted A. Smooth endoplasmic reticulum
of 1-2 layers of cubic cells. There was also B. Ribosomes
a bright red membrane around the ovocyte. C. Lysosomes
What follicle is it? D. Cell centre
A. Secondary E. Golgi apparatus
B. Primordilal 11. As a result of prophylactic meedical

2. examination a 7 year old boy was diagnosed B. Intensification of glucose absorption m
with Lesch-Nyhan syndrome (only boys fall the bowels
ill with it). The boy's parents are healthy but C. Gluconeogenesis activation
his grandfather bv his mother's side suffers D. Glycogenogenesis activation
from the same disease. What type or disease E. Inhibition of glycogen synthesis
inheritance is it? 16. A man with a stab wound in the area of
A. Dominant, sex-linked quadrilateral foramen applied to a doctor.
B. Recessive, sex-linked Examination revealed that the patient was
C. Autosomal recessive unable to draw his arm aside from his body.
D. Autosomal dominant What nerve is most probably damaged?
E. Semidominance A. N.axillaris
12. A patient ill with chronic cardiac B. N.radialis
insufficiency was prescribed an C. N.subclavius
average therapeutic dose of digoxin. Two D. Nmedianus
weeks after begin of its taking there E. N ulnaris
appeared symptoms of drug intoxication 17. Ultramicroscopical examination of
(bradycardia, extrasystole, nausea). Name "dark" hepatocyte population in the cell
the phenomenon that caused accumulation cytoplasm detected a developed granular
of the drug in the organism? endoplasmic reticulum. What function has
A. Material cumulation this organella in these cells?
B. Tolerance A. Bile production
C. Functional cumulation B. Deintoxicative function
D. Idiosyncrasy C. Calcium ion depositing
E. Tachyphylaxis D. Carbohydrate synthesis
13. Bacterioscopic examination of a smear E. Synthesis of blood plasma proteins
from the pharynx of a diphtheria suspect 18. A 17 year old boy fell seriously ill, the
revealed bacilli with volutine granules. What body temperature rose up to 38,5°C, there
etiotropic drug should be chosen in this appeared cough, rhinitis, lacrimation, nasal
case? discharges. What inflammation is it?
A. Eubiotic A. Hemorrhagic
B. Antidiphtheritic antitoxic serum B. Purulent
C. Bacteriophage C. Fibrinous
D. Diphtheritic anatoxin D. Catarrhal
E. Interferon E. Serous
14. A culture of monkey cells (Vero) and 19. Researchers isolated 5 isoenzymic forms
a group of mouse sucklings were infected of lactate dehydrogenase from the human
with an inoculum taken from a child with blood serum and studied their properties.
provisional diagnosis "enterovirus infection". What property indicates that the isoenzymic
There was no cytopathic effect on the forms were isolated from the same enzyme?
cell culture but mouse sucklings died. What A. The same electrophoretic mobility
enteric viruses might have caused disease of B. Tissue localization
this child? C. The same molecular weight
A. Coxsackie B D. The same physicochemical properties
B. Coxsackie A E. Catalyzation of the same reaction
C. Unclassified enteric viruses 68-71 20. A 60 year old patient has impaired
D. ECHO virus perception of high-frequency sounds. These
E. Polioviruses changes were caused by damage of the
15. A patient ill with neurodermatitis has following auditory analyzer structures:
been taking prednisolone for a long time. A. Tympanic membrane
Examination revealed high rate of sugar in B. Main cochlea membrane near the oval
his blood. This complication is caused by window
the drug influence upon the following link C. Eustachian tube
of carbohydrate metabolism: D. Middle ear muscles
A. Activation of insulin decomposition E. Main cochlea membrane near the helicotrema

3. 21. ECG of a patient with hyperfunction of D. Biotin
thyroid gland showed heart hurry. It is indicated E. Vitamin A
by depression of the following ECG 26. A patient ill with essential hypertension
element: was recommended a drug that prevents
A. QRS complex thrombosis. It is to be taken parenterally.
B. R - R interval What drug is it?
C. P – Q interval A. Protamine sulfate
D. P – Q segment B. Amben
E. P - T interval C. Heparin
22 A patient taking clonidine for essential D. Neodicumarin
hypertension treatment was using alcohol E. Syncumar
that caused intense inhibition of central 27. A 38 year old patient suffers from
nervous system. What may it be connected rheumatism in its active phase. What
with? laboratory characteristic of blood serum
A. Intoxication is of diagnostic importance in case of this
B. Idiosyncrasy pathology?
C. Cumulation A. Uric acid
D. Effect potentiating B. Creatinine
E. Effect summation C. C-reactive protein
23. A patient is ill with diabetes mellitus D. Transferrin
accompanied by hyperglycemia on E. Urea
an empty stomach (7,2 millimole/l). The 28. A 28 year old man had a gunshot wound
hyperglycemia rate can be retrospectively of shin that resulted in an ulcer from the side
estimated (over the last 4-8 weeks before of the injury. What is the main factor of
the examination) on the ground of the rate neurodystrophy pathogenesis in this case?
of the following blood plasma protein: A. Microcirculation disturbance
A.Albumin B. Infection
B. Ceruloplasmin c. Tissue damage
C. Fibrinogen D. Psychical stress
D. Glycated hemoglobin E. Traumatization of peripheral nerve
E. C-reactive protein 29. A 26 year old man is in the torpid shock
24. 6 months after labour a woman had Phase as a result of a car accident. In blood:
uterine hemorrhage. Gynaecological examination 3,2· 109/1. What is the leading mechanism of
of uterine cavity revealed a dark-red leukopenia development?
tissue with multiple cavities resembling of A. Leikopoiesis inhibition
a "sponge". Microscopic examination of a B. Redistribution of leukocytes m
tumour revealed in blood lacunas atypic light bloodstream
epithelial Langhans cells and giant cells C. Disturbed going out of mature leukocytes
of syncytiotrophoblast. What tumour is it? from the marrow into the blood
A. Adenocarcinoma D. Lysis of leukocytes in the blood-forming
B. Cystic mole organs
C. Fibromyoma E. Intensified elimination of leukocytes from
D. Chorioepithelioma the organism
E. Squamous cell nonkeratinous carcinoma 30. Parents of a 3 year old child have
25. A 3 year old child with symptoms of been giving him antibiotics with purpose of
stomatitis, gingivitis and dermatitis of open preventing enteric infections for a long time.
skin areas was delivered to a hospital. A month later the child's condition changed
Examination revealed inherited disturbance for the worse. Blood examination revealed
of neutral amino acid transporting in the apparent leukopenia and granulocytopenia.
bowels. These symptoms were caused by the What is the most probable mechanism of
deficiency of the following vitamin: blood changes?
A. Niacin A. Autoimmune
B. Pantothenic acid B. Myelotoxic
C. Cobalamin C. Redistributive

4. D. Age-specific traumatology department. Objectively: cut
E. Hemolytic wound of palmar surface of left hand: middle
31. Examination of a 12 year old boy with phalanxes of II-V fingers don't bend.
developmental lag revealed achondroplasia: What muscles are damaged?
shortening of upper and lower limbs as a A. Palmar interosseous muscles
result of growth disorder of epiphyseal cartilages B. Profound finger flexor
of long tubal bones. This disease is: C. Dorsal interosseous muscles
A. Acquired D. Lumbrical muscles
B. Inherited, dominant E. Superficial finger flexor
C. Inherited, sex-linked 36. A 65 year old man suffering from
D. Congenital gout complains of kidney pain. Ultrasound
E. Inherited, recessive examination revealed renal calculi. The
32. Hartnup disease is caused by point most probable cause of calculi formation
mutation of only one gene which results in is the strengthened concentration of the
disturbance of tryptophane absorption in following substance:
the bowels and its resorption in the renal A. Uric acid
tubules. It is the reason for disorder of B. Cholesterol
both digestive and urination systems. What C. Bilirubin
genetic phenomenon is observed in this D. Urea
case? E. Cystine
A. Polymery 37. A patient with frequent attacks of
B. Complementary interaction stenocardia was prescribed sustak-forte to
C. Pleiotropy be taken one tablet twice a day. At first
D. Semidominance the effect was positive but on the second
E. Codominance day stenocardia attacks resumed. What can
33. A 46 year old patient applied to a doctor explain inefficiency of the prescribed drug?
complaining about joint pain that becomes A. Tachyphylaxis
stronger the day before weather changes. B. Sensibilization
Blood examination revealed strengthened C. Dependence
concentration of uric acid. The most D. Cumulation
probable cause of the disease is the intensified E. Idiosyncrasy
disintegration of the following substance: 38. An aged man had raise of arterial
A. Uridine triphosphate pressure under a stress. It was caused by
B. Thymidine monophosphate activation of:
C. Uridine monophosphate A. Functions of thyroid gland
D. Adenosine monophosphate B. Sympathoadrenal system
E. Cytidine monophosphate C. Functions of adrenal cortex
34. A 28 year old patient had high arterial D. Hypophysis function
pressure, hematuria and facial edemata. In E. Parasympathetic nucleus of vagus
spite of treatment renal insufficiency was 39. A cerebral trauma caused increased
progressing. 6 months later the patient died ammonia generation. What amino acid
from uremia. Microscopic examination participates in the excretion of ammonia
of his kidneys and their glomerules revealed from the cerebral tissue?
proliferation of capsule nephrothelium and A. Glutamic
of podocytes with "demilune "formation, B. Lysine
sclerosis and hyalinosis of glomerules. What C. Tyrosine
disease corresponds with the described picture? D. Tryptophan
A. Acute glomerulonephritis E. Valine
B. Subacute glomerulonephritis 40. As a result of posttranslative modifications
C. Nephrotic syndrome some proteins taking part in blood
D. Chronic glomerulonephritis coagulation, particularly prothrombin,
E. Acute pyelonephritis become capable of calcium binding. The
35. A 35 year old man with a trauma following vitamin takes part in this process:
of his left hand was admitted to the A. B2

5. B. B1 46. While palpating mammary gland of a
C. A patient a doctor revealed an induration
D. C in form of a node in the inferior medial
E. K quadrant. Metastases may extend to the
41. A student takes notes of a lecture. Quality following lymph nodes:
of his notes became significantly worse when his A. Superior diaphragmal
neighbours began talking. What B. Profound lateral cervical
type of conditional reflex inhibition was the C. Bronchopulmonary
cause of it? D. Posterior mediastinal
A. Protective E. Parasternal
B. Differentiated 47. A gynaecologist was examining a patient
C. External and revealed symptoms of genital tract
D. Delayed inflammation. A smear from vagina contains
E. Extinctive pyriform protozoa with a spine, flagella
42. A 7 vear old child is ill with bronchilis. It is at their front: there is also an undulating
necessary to administer him an membrane. What disease can be suspected?
antibacterial drug. What drug of fluoroquinolone A. Intestinal trichomoniasis
group is CONTRA-INDICATED at B. Toxoplasmosis
this age? C. Lambliasis
A. Cyprofloxacin D. Urogenital trichomoniasis
B. Sulfadimethoxine E. Balantidiasis
C. Ampiox 48. In course of an experiment a big number
D. Ampicillin of stem cells of red bone marrow was in
E. Amoxicillin some way destructed. Regeneration of which
43. A patient is ill with hepatocirrhosis. cell populations in the loose connective
State of antitoxic liver function can be tissue will be inhibited?
characterized by examination of the following A. Of lipocytes
substance exreted by urine: B. Of fibroblasts
A. Uric acid C. Of pericytes
B. Hippuric acid D. Of pigment cells
C. Ammonium salts E. Of macrophags
D. Amino acids 49. A pregnant woman had her blood group
E. Creatinine identified. Reaction of erythrocyte agglutination
44. A patient suffering from chronic cardiac with standard serums of 0αβ (I), Bα
insufficiency was recommended to undergo (III) groups didn't proceed with standard
a prophylactic course of treatment with a serum of Aβ (II) group. The blood group
cardiological drug from the group of cardiac under examination is:
glycosides that is to be taken enterally. What A. Aβ (II)
drug was recommended') B. AB (IV)
A. Corglycon C. Bα (III)
B. Cordiamin D. -
C. Strophanthine E. 0αβ(I)
D. Cordarone 50. Prophylactic medical examination of a
E. Digoxin 36 year old driver revealed that his AP was
45. 48 hours after tuberculine test (Mantoux 150/90 mm Hg. At the end of working day he
test) a child had a papule 10 mm in diameter usually hears ear noise, feels slight indisposition
on the spot of tuberculine injection. What that passes after some rest. He was diagnosed
hypersensitivity mechanism underlies these with essential hypertension. What
changes? is the leading pathogenetic mechanism in
A. Anaphylaxy this case?
B. Granulomatosis A. Neurogenetic
C. Antibody-dependent cytotoxicity B. Endocrinal
D. Cellular cytotoxicity C. Reflexogenic
E. Immunocomplex cytotoxicity D. Nephric

6. E. Humoral "progressing muscular dystrophy" got his
51. A histological specimen of spleen urine tested. What compound will confirm
shows a vessel with a wall consisting this diagnosis if found in urine?
of endothelium and subendothelial layer, A. Kreatine
median membrane is absent, exterior B. Calmodulin
membrane inosculates with the layers of C. Collagen
spleen connective tissue. What vessel is it? D. Myoglobin
A. Artery of muscular type E. Porphyrin
B. Capillary 57. While playing volleyball a sportsman
C. Vein of muscular type made a jump and landed on the outside
D. Arteriole edge of his foot. He felt acute pain in the
E. Vein of non-muscular type talocrural joint, active movements are limited,
52. It was revealed that T-lymphocytes passive movements are unlimited but
were affected by HIY. Virus enzyme reverse painful. A bit later there appeared a swelling
transcriptase (RN A -dependent in the area of external ankle, the skin
DNA polymerase) - catalyzes the synthesis became red and warm. What type of peripheral
of: circulation disturbance is the case?
A. Viral DNA on DNA matrix A. Arterial hyperemia
B. Virus informational RNA on the matrix of B. Venous hyperemia
DNA C. Stasis
C. DNA on virus ribosomal RNA D. Embolism
D. DNA on the matrix of virus mRNA E. Thrombosis
E. mRNA on the matrix of virus protein 58. Autopsy of a man who had been working
53. Planned mass vaccination of all newborn as a miner for many years and died from
5-7 day old children against tuberculosis plays cardiopulmonary decompensation revealed
an important role in tuberculosis prevention. that his lungs were airless, sclerosed, their
In this case the following vaccine is apexex had emphysematous changes, the
applied: lung surface was greyish-black, the incised
A.BCG lung tissue was coal-black. What disease
B. Adsorbed diphtheria vaccine caused death?
C. Diphteria and tetanus toxoids and A. Silicosis
pertussis vaccine B. Talcosis
D. Diphtheria and tetanus anatoxin vaccine C. Anthracosis
E. - D. Aluminosis
54. Life cycle of a cell includes the process E. Asbestosis
of DNA autoreduplieation. As a result of it 59. Examination of a 55 year old woman
monochromatid chromosomes turn into revealed under the skin of submandibular
bichromatid area a movable slowly growing pasty
ones. What period of cell cycle formation with distinct borders l,0x0,7 cm
does this phenomenon fall into? large. Histological examination revealed
A. G2 Iipocytes
B. Go that form segments of diffrent forms
C. G1 and sizes separated from each other by
D. S thin layers of connective tissue with vessels.
E. M What is the most probable diagnosis?
55. Rest potential of a cell equals -80 mV. A. Lipoma
At what stage of action potential did the B. Fibroma
membrane potential equal +30 mV? C. Liposarcoma
A. After depolarization D. Fibrosarcoma
B. After hyperpolarization E. Angioma
C. Reverse polarization 60. A patient is 44 years old. Laboratory
D. - examination of hrs blood revealed that
E. Depolarization content of proteins in plasma was 40 g/l.
56. A patient with suspected diagnosis What influence will be exerted on the

7. transcapillary water exchange? C. M.rhomboideus minor
A. Exchange will stay unchanged . D. M.latissimus dorsi
B. Filtration will be increased, reabsorption- E. M.sternocleidomastoideus
decreased 65. A patient with a knife wound in the
C. Filtration will be decreased, reabsorption left lumbal part was delivered to the
- increased emergency hospital. In course of operation
D. Both filtration and reabsorption will be a surgeon found that internal organs were
increased not damaged but the knife injured one of
E. Both filtration and reabsorption will be muscles of renal pelvis. What muscle is it?
decreased A. Iliac muscle
61. A 30 year old woman has face edemata. B. Abdominal internal oblique muscle
Examination revealed proteinuria (5,87 g/l), C. Erector muscle of spine
hypoproteinemia, dysproteinemia, D. Greater psoas muscle
hyperlipidemia. E. Abdominal external oblique muscle
What condition is the set of these 66. A 56 year old patient came to a hospital
symptoms typical for? with complaints about general weakness,
A. Chronic renal failure tongue pain and burning, sensation of limb
B. Nephritic syndrome numbness. In the past he underwent resection of
C. Nephrotic syndrome forestomach. In blood: Hb- 80 g/l;
D. Chronic pyelonephritis erythrocytes – 2,0*1012/l; colour index - 1.2,
E. Acute renal failure leukocytes – 3,5*109/l. What anemia type is
62. Vitamin B1 deficiency results in disturbance it?
of oxidative decarboxylation of α-ketoglutaric A. Hemolytic
acid. This will disturb synthesis B. B12-folate deficient
of the following cocnzyme: C. Aplastic
A. Nicotinamide adenine dinucleotide D. Posthemorrhagic
(NAD) E. Iron-deficient
B. Lipoic acid 67. A patient ill with thrombophlehitis of his
C. Flavine adenine dinucleotide (FAD) lower limbs had chest pain, blood spitting,
D. Thiamine pyrophosphate progressing respiratory insufficiency that led
E. Coenzyme A to his death. Autopsy diagnosed multiple
63. Skin of a man who died from cardiac lung a infarctions. What is the most probable
insufficiency has an eruption in form cause of their development?
of spots and specks. There are also A. Thromboembolism of pulmonary artery
bedsores in the area of sacrum and spinous branches
vertebral processes. Microscopical B. Thrombosis of bronchial arteries
examination of CNS, skin, adrenal glands C. Thrombosis of pulmonary artery branches
revealed in the vessels of microcirculatory D. Thrombosis of pulmonary veins
bed and in small arteries destructiveproliferative E. Thromboembolism of bronchial arteries
endothrombovasculitis with 68. A concentrated solution of sodium
Popov's granulomas; interstitial myocarditis. chloride was intravenously injected to an
What diagnosis corresponds with the described animal. This caused decreased reabsorption
picture? of sodium ions in the renal tubules. It is the
A. Spotted fever result of the following changes of hormonal
B. Q fever secretion:
C. Nodular periarteritis A. Aldosterone increase
D. Enteric fever B. Reduction of atrial natriuretic factor
E. HIV C. Vasopressin increase
64. A man with an injury of the dorsal area D. Aldosterone reduction
of his neck was admitted to the resuscitation E. Vasopressin reduction
department. What muscle occupies this 69. A patient had hemorrhagic stroke. Blood
area? examination revealed strengthened kinin
A. M.trapezius concentration.The patient was prescribed
B. M.scalenus anterior contrical. It was administered in order to

8. inhibit the following proteinase: heart structure:
A. Trypsin A. Ventricle
B. Chemotrypsin B. Sinoatrial node
C. Pepsin C. Atrioventricular node
D. Collagenase D. His' bundle
E. Kallikrein E. Atrium
70. Packed cell volume of a man was 40% 76. Examination of coronary arteries
before the trauma. What packed cell volume revealed atherosclerotic calcified plaques
will be observed 24 hours after blood loss of closing vessel lumen by 1/3. The muscle has
750 ml? multiple whitish layers of connective tissue.
A.40% What process was revealed in the myocardium?
B.30% A. Postinfarction cardiosclerosis
C.55% B. Myocardium infarction
D.50% C. Diffusive cardiosclerosis
E.45% D. Myocarditis
71. On the 2-3rd day after stomach resection E. Tiger heart
intestinal peristalsis wasn't restored. What 77. A patient with cholelithiasis fell ill with
is to be administered for stimulation of mechanic jaundice. Examination revealed
gastrointestinal tract? that the stone was in the common bile
A. Atropine sulfate duct. What bile-excreting ducts make up the
B. Prasosin obturated duct?
C. Acetylcholine A. Ductus hepaticus sinister et ductus cysticus
D. Proserin B. Ductus hepaticus dexter et sinister
E. Cyclodole C. Ductus hepaticus communis et ductus
72. An ophthalmologist used a 1% mesaton choledochus
solution for the diagnostic purpose (pupil dilation D. Ductus hepnriclls C0l11111W1lS et ductus
for eve-ground examination). What is cllOledochlls
the cause of mydriasis induced by the drug? E. Ductus hepaticus dexter ct ductus cysticus
A. Activation of α1 adrenoreceptors 78. 2 years ago a patient underwent resection
B. Activation of β1 adrenoreceptors of pyloric part of stomach. He complains
C. Activation of M-cholinoreceptors of weakness, periodical dark shadows
D. Block of α1 adrenoreceptors beneath his eyes, dyspnea. In blood: Hb - 70
E. Activation of α2 adrenoreceptors g/l erythrocytes - 3,0 * 1012 /1, colour index
73. A patient with disturbed cerebral circulation - 0,7. What changes of erythrocytes in blood
has problems with deglutition. smears are the most typicat for this condition?
What part of brain was damaged? A. Macrocytes
A. Interbrain B. Ovalocytes
B. Cervical part of spinal cord C. Megalocytes
C. Midbrain D. Schizocytes
D. Brainstem E. Microcytes
E. Forebrain 79. A 6 year old child was delivered to a
74. A 16 year old boy after an illness has hospital. Examination revealed that the child
diminished function of protein synthesis in couldn't fix his eves, didn't keep his eyes
liver as a result of vitamin K deficiency. It on toys, eye ground had the cherry-red spot
will cause disturbance of: sign. Laboratory analyses showed that brain,
A. Blood coagulation Iiver and spleen had high rate of ganglioside
B. Anticoagulant generation glycometide. What congenital disease is the
C. Erythropoietin secretion child ill with?
D. Erythrocyte sedimentation rate A. Wilson's syndrome
E. Osmotic blood pressure B. MacArdle disease
75. An isolated cell of human heart C. Niemann-Pick disease
automatically generates excitement D. Tay-Sachs disease
impulses with frequency of 60 times per minute. E. Turner's syndrome
This cell was taken from the following 80. In course of an experiment a peripheral

9. section of vagus of an expiremental animal B. Retinol acetate
is being stimulated. What changes will be C. Levamisole
observed? D. Prednisolone
A. Heart rate fall E. Retabolil
B. Heart hurry 86. A stomatologist injected a patient with
C. Increase of respiration rate a certain drug in order to reduce salivation
D. Bronchi dilation during tooth filling. What drug is it?
E. Pupil dilation A. Mesaton
81. A patient with bacterial pneumonia B. Proserin
was prescribed benzylpenicillin. What is the C. Atropine sulfate
mechanism of its antibacterial effect? D. Adrenaline hydrochloride
A. Abnormal permeability of cytoplasmic E. Pilocarpine hydrochloride
membrane 87. Vagus branches that innervate heart are
B. Inhibition of SH-groups of microorganism being stimulated in course of an experiment.
enzymes As a result of it the excitement conduction
C. Inhibition of synthesis of microorganism from atria to the ventricles was brought to a
wall stop. It is caused by electrophysical changes
D. Inhibition of intracellular protein in the following structures:
synthesis A. His' bundle
E. Antagonism with p-amino-benzoic acid B. Atria
82.Blood minute volume of a 30 year old woman C. Atrioventricular node
at rest is 5 l/m. What blood volume D. Sinoatrial node
is pumped through the pulmonary vessels E. Ventricles
per minute? 88. A doctor examined a child and revealed
A. 3,75 l symptoms of rachitis. Development of this
B. 1,5 l desease was caused by deficiency of the
C. 2,5 l following compound:
D. 2,0 l A. Naphtaquinone
E. 5,1 B. Retinol
83. In course of an experiment a toad's right C. Biotin
labyrinth was destroyed. It will cause D. 1,25 [OH]-dichydroxycholecalciferol
amyotonia of the following muscles: E. Tocopherol
A. Right and left extensors 89. Histological examination of a skin tissue
B. Right extensors sampling revealed granulomas consisting
C. Left flexors of macrophagal nodules with lymphocytes
D. Right flexors and plasmatic cells. There are also some big
E. Left extensors macrophages with fatty vacuoles containing
84. A patient died from cardiopulmonary causative agents of a disease packed up in
decompensation. Histological examination form of spheres (Virchow's cells). Granulation
revealed diffused pulmonary lesion together tissue is well vascularized. What disease
with interstitial edema. infiltration of tissue is this granuloma typical for?
by limphocytes, macrophages, plasmocytes, A. Rhinoscleroma
pulmonary fibrosis, panacinar emphysema. B. Syphilis
What disease corresponds with the described C. Lepra
picture? D. Tuberculosis
A. Pulmonary atelectasis E. Glanders
B. Bronchial asthma 90. A patient consulted a stomatologist
C. Fibrosing alveolitis about purulent inflammation of his gums.
D. Chronic bronchitis What drug will be the most effective if it
E. Bronchopneumonia is suspected that a causative agent is an
85. In order to accelerate healing of a radiation anaerobe?
ulcer a vitamin drug was administered. A. Oxacillin sodium
What drug is it? B. Gentamicin
A. Methyluracil C. Nitroxoline

10. D. Co-trimoxazole diagnosis?
E. Metronidazole A. Pediculosis
91. Microscopy of stained (Ziehl-Neelsen B. Myiasis
staining) smears taken from the sputum C. Scabies
of a patient with chronic pulmonary disease D. Demodicosis
revealed red bacilli. What property E. Phthiriasis
of tuberculous bacillus was shown up? 96. Examination of a patient with pustular
A. Acid resistance skin lesions allowed to isolate a causative
B. Alcohol resistance agent that forms in the blood agar roundish
C. Capsule formation yellow middle-sized colonies surrounded by
D. Sporification haemolysis zone. Smears from the colonies
E. Alkali resistance contain irregular-shaped clusters of grampositive
92. The upper lobe of the right lung cocci. The culture is oxidase- and
is enlarged, grey and airless, the inscision catalase-positive, ferments mannitol and
surface is dripping with turbid liquid, synthesizes plasmocoagulase. What causative
the pleura has many fibrinogenous films; agent was isolated?
microscopical examination of alveoles A. Staphylococcus saprophyticus
revealed exudate containing neutrophils, B. Staphylococcus aureus
desquamated alveolocytes and fibrin fibers. C. Staphylococcus epidermidis
The bronchus wall is intact. What is the most D. Streptococcus agalactiae
probable diagnosis? E. Streptococcus pyogenes
A. Focal pneumonia 97. Inoculum from pharynx of a patient
B. Pulmonary abscess ill with angina was inoculated into bloodtellurite
C. Inf1uenzalpneumonia agar. It resulted in growth of grey, radially
D. Croupous pneumonia striated (in form of rosettes) colonies 4-5 -mm in
E. Interstitial pneumonia dian1eter. Gram-positive bacilli with clublike
93. A patient has a decreased vasopressin thickenings on their ends
synthesis that causes polyuria and as a result placed in form of spread wide apart fingers
of it evident organism dehvdratation. What are visible by microscope. What microorganisms
is the mechanism of polyuria development? are these?
A. Reduced tubular reabsorption of protein A. Streptococci
B. Reduced tubular reabsorption of Na ions B. Botulism clostridia
C. Reduced glucose reabsorption C. Diphtheria corynebacteria
D. Reduced tubular reabsorption of water D. Streptobacilli
E. Acceleration of glomerular filtration E. Diphtheroids
94. A patient of surgical department 98. A man with a wound of his limb that had
complains about pain in the small of her been suppurating for a long time died from
back and in the lower part of her belly; painful intioxication. Autopsy revealed extreme
and frequent urination. Bacteriological emaciation, dehydration, brown atrophy of
examination of urine revealed gramnegative liver. myocardium, spleen and cross-striated
oxidase-positive rod-like bacteria muscles as well as renal amyloidosis. What
forming greenish mucoid colonies with. specific diagnosis corresponds with the described picture?
smell. What causative agent can it be? A. Chroniosepsis
A. Mycoplasma pneumonie B. Brucellosis
B. E.coli C. Chernogubov's syndrome
C. Pseudomonas aeruginosa D. Septicopyemia
D. Proteus mirabilis E. Septicemia
E. Str.pyogenes 99. In course of severe respiratory viral
95. A patient has acne on his face. Microspcopic infection there appeared clinical signs of
examination of scrapings from progressing cardiac insufficiency that caused
the affected areas revealed living porrect death of a patient in the 2nd week of disease.
vermiform arthropoda 0,2-0,5 mm large with Autopsy revealed that the heart was
four pairs of short extremities in the front sluggish, with significant cavity dilatation.
part of their bodies. What is the laboratory Histological examination of myocardium

11. revealed plephora of microvessels and diffuse D. Sodium
infiltration of stroma by lymphocytes E. Calcium
and histiocytes. What disease corresponds 104. An unconscious young man with signs
with the described picture? of morphine poisoning entered admission
A. Stenocardia office. His respiration is shallow and
B. Cardiomyopathy infrequent which is caused by inhibition of
C. Acute coronary insufficiency respiratory centre. What type of respiratory
D. Myocardium infarction failure is it?
E. Myocarditis A. Ventilative restrictive
100. A patient consulted a doctor about B. Perfusive
symmetric dermatitis of open skin areas. It C. Ventilative obstructive
was found out that the patient lived mostly D. Ventilative dysregulatory
on cereals and ate too little meat, milk and E. Diffusive
eggs. What vitamin deficiency is the most 105. A patient being treated for viral
evident? hepatitis type B got symptoms of hepatic
A. Nicotinamide insufficiency. What blood changes indicative
B. Biotin of protein metabolism disorder will be
C. Tocopherol observed in this case?
D. Folic acid A. Absolute hyperfibrinogenemia
E. Calciferol B. Absolute hyperalbuminemia
101. A patient with clinical signs of C. Absolute hypoalbuminemia
encephalitis was delivered to the infectious D. Proteinic blood composition is unchanged
diseases hospital. Anamnesis registers a tick E. Absolute hyperglobulinemia
bite. Hemagglutination-inhibition reaction 106. A patient ill with essential arterial
helped to reveal antibodies to the causative hypertension had a hypertensic crisis that
agent of tick-borne encephalitis in the dilution resulted in an attack of cardiac asthma.
1:20 which is not diagnostic. What actions What is the leading mechanism of cardiac
should the doctor take after he had got such ins insufficiency in this case?
result? A. Absolute coronary insufficiency
A. To repeat examination with another B. Heart overload caused by increased blood
diagnosticum volume
B. To repeat the examination with scrum C. Heart overload caused by high pressure
taken 10 days later D. Myocardium damage
C. To deny diagnosis of tick-borne encephalitis E. Blood supply disturbance
D. To examine the same serum 107. Surgical removal of a part of stomach
E. To apply more sensitive reaction resulted in disturbed absorption of vitamin
102. Parents of a 10 year old boy consulted B12 , it is excreted with feces. The patient
a doctor about extension of hair-covering, was diagnosed with anemia. What factor is
growth of beard and moustache, low voice. necessary for absorption of this vitamin?
Intensified secretion of which hormone must A. Gastromucoprotein
be assumed? B. Hydrochloric acid
A. Of testosterone C. Gastrin
B. Of somatotropin D. Folic acid
C. Of progesterone E. Pepsin
D. Of oestrogen 108. A 45 year old man consulted a doctor
E. Of cortisol about a plaque-like formation on his neck.
103. An animal with aortic valve insufficiency Histological examination of a skin bioptate
got hypertrophy of its left heart ventricle. revealed clusters of round and oval tumour
Some of its parts have local contractures. cells with a narrow border of basophilic
What substance accumulated in the cytoplasm resembling of cells of basal epidermal
myocardiocytes caused these contractures? layer. What tumour is it?
A. Lactic acid A. Epidermal cancer
B. Potassium B. Hydroadenoma
C. Carbon dioxide C. Trichoepithelioma

12. D. Basal cell carcinoma 114. The territory of an old burial ground for
E. Syringoadenoma animal refuse that hasn't been used for over
109. A 45 year old woman is ill with breast 50 years is meant for house building. But soil
cancer. Her left arm has symptoms of investigation showed the presense of viable
lymphatic system insufficiency - limb edema, spores of a causative agent causing a very
lymph node enlargement. What form of dangerous disease. What microorganism might
lymphatic circulation insufficiency is it? have been preserved in soil for such a
A. Mechanic insufficiency long period of time?
B. - A. Bacillus anthracis
C. Dynamic insufficiency B. Francisella tularensis
D. Combined insufficiency C. Mycobacterium bovis
E. Resorption insufficiency D. Brucella abortus
110. Mother of a 2 year old child consulted E. Yersinia pestis
a stomatologist. In the period of pregnancy 115. During starvation muscle proteins
she was irregularly taking antibiotics for an break up into free amino acids. These
infectious disease. Examination of the child compounds will be the most probably
revealed incisor destruction, yellow enamel, involved into the following process:
brown rim around the dental cervix. What A. Glycogenolysis
drug has apparent teratogenic effect? B. Decarboxylation
A. Ampiox C. Gluconeogenesis in muscles
B. Octadine D. Gluconeogenesis in liver
C. Furosemide E. Synthesis of higher fatty acids
D. Doxacycline 116. A 62 year woman complains of frequent
E. Xantinol nicotinate pain attacks in the area of her chest
111. A man who has been taking a drug for and backbone, rib fractures. Her doctor
a long time cannot withhold it because this suspected myeloma (plasmocytoma). What
causes impairment of psychic, somatic and of the following laboratory characteristics
vegetative functions. Name the syndrome will be of the greatest diagnostic
of different disturbances caused by drug importance?
discontinuation: A. Idiosyncrasy A. Hypoproteinemia
B. Sensibilization B. Hyperalbuminemia
C. Tachyphylaxis C. Hypoglobulinemia
D. Abstinence D. Paraproteinemia
E. Cumulation E. Proteinuria
112. A chemical burn caused esophagus 117. The cerebrospinal fluid is being examined
stenosis. Difficulty of ingestion led to the for the purpose of diffrential meningitis
abrupt loss of weight. In blood: 3,0 * 1012/l, diagnostics. At what site is the lumbal
Hb - 106 g/,. crude protein - 57 g/l. What puncture safe?
type of starvation is it? A. L II - L III
A. Water B. L V – S I
B. Incomplete C. Th XIl - L I
C. Complete D. L III – L IV
D. Proteinic E. L I - L II
E. Absolute 118. Power inputs of a man were measured.
113. As a result of long-term starvation In what state was this man if his power
the glomerular filtration of a man was inputs were lower than basal metabolism?
accelerated by 20%. The most probable A. Nervous tension
cause of filtration changes under such conditions B. Sleep
is: C. Rest
A. Fall of oncotic pressure of blood plasma D. Relaxation
B. Increase of renal plasma flow E. Simple work
C. Growth of filtration coefficient 119. Vagi of an experimental animal were
D. Rise of systemic arterial pressure cut on both sides. What respiration changes
E. Increased permeability of renal filter will be observed?

13. A. It will become shallow and frequent C. Heterotransplantation
B. It will become shallow and infrequent D. Isotransplantation
C. No changes will be observed E. Allotransplantation
D. It will become deep and infrequent 125. A 40 year old man noticed a reddening
E. It will become deep and frequent and an edema of skin in the area of his neck
120. Pharmacological effects of antidepressants that later developed into a small abscess.
arc connected with inhibition The incised focus is dense, yellowish-green.
of an enzyme catalyzing biogenic amines The pus contains white granules. Histological
noradrenaline and serotonine in the examination revealed drusen of a fungus,
mitochondrions plasmatic and xanthome cells, macrophages.
of cerebral neurons. What What type of mycosis is the most probable?
enzyme participates in this process? A. Sporotrichosis
A. Lyase B. Actinomycosis
B. Monoamine oxidase C. Aspergillosis
C. Transaminase D. Candidosis
D. Peptidase E. Coccidioidomycosis
E. Decarboxylase 126. An embryo displays disturbed process
121. A pathological process in bronchi of dorsal mesoderm segmentation and somite
resulted in epithelium desquamation. What formation. What part of skin will have
cells will regenerate bronchial epithelium? developmental abnormalities?
A. Intercalary A. Epidermis
B. Ciliate B. Derma
C. Goblet C. Sudoriferous glands
D. Basal D. Sebaceous glands
E. Endocrinal E. Hair
122. Examination of a man who had been 127. In course of a conditional experiment
working hard under higher temperature the development of mesenchyma cells was
of the environment revealed abnormal completely inhibited. Development of the
quantity of blood plasma proteins. What following muscular tissue will be disturbed:
phenomenon is the case? A. Cardiac muscular tissue
A. Absolute hyperproteinemia B. Smooth muscular tissue
B. Paraproteinemia C. Skeletal muscular tissue
C. Relative hyperproteinemia D. Neural muscular tissue
D. Absolute hypoproteinemia E. Epidermal muscular tissue
E. Dysproteinemia 128. A girl is diagnosed with adrenogenital
123. A 70 year old man IS ill with syndrome (pseudohermaphroditism). This
vascular atherosclerosis of lower extremities pathology was caused by hypersecretion of
and coronary heart disease. Exan1ination the following adrenal hormone:
revealed disturbance of lipidic A. Adrenalin
blood composition. The main factor of B. Estrogen
atherosclerosis pathogenesis is the excess C. Aldosterone
of the following lipoproteins: D. Androgen
A. Low-density lipoproteins E. Cortisol
B. Cholesterol 129. Golgi complex exports substances from
C. Chylomicrons a cell due to the fusion of the membrane
D. High-density lipoproteins saccule with the cell membrane. The saccule
E. Intermediate density lipoproteins contents flows out. What process is it?
124. For the purpose of myocardium A. Exocytosis
infarction treatment a patient was injected B. Facilitated diffusion
with embryonal stem cells derived from this C. Endocytosis
very patient by means of therapeutic cloning. D. Active- transport
What transplantation type is it? E. All answers arc false
A. Autotransplantation 130. An oncological patient was prescribed
B. Xenotransplantation methotrexate. With the lapse of time target

14. cells of the tumour lost susceptibility to this face, hirsutism, AP is 165/100 mm Hg, height
drug. There is change of gene expression of - 164 cm, weight - 103 kg; the fat is
the folowing enzyme: mostly accumulated on her neck, thoracic
A. Thiaminase girdle, belly. What is the main pathogenetic
B. Deaminase mechanism of obesity?
C. Dehydrofolate reductase A. Increased production of glucocorticoids
D. Folate decarboxylase B. Reduced glucagon production
E. Folate oxidase C. Increased insulin production
131. An infant has apparent diarrhea resulting D. Reduced production of thyroid hormones
from improper feeding. One of the main E. Increased mineralocorticoid production
diarrhea effects is plentiful excretion of sodium 136. A 20 year old patient died from
bicarbonate. What form of acid-base intoxication 8 days after artificial illegal
balance disorder is the case? abortion performed in her 14-15th week of
A. Metabolic alkalosis pregnancy. Autopsy of the corpse revealed
B. Respiratory alkalosis yellowish colour of eye sclera and of skin,
C. No disorders of acid-base balance will be necrotic suppurative endometritis, multiple
observed pulmonary abscesses, spleen hyperplasia
D. Respiratory acidosis with a big number of neutrophils in its sinuses.
E. Metabolic acidosis What complication after abortion was
112. Workers of a hothouse farm work under developed?
conditions of unfavourable microclimate: air A. Chroniosepsis
temperature is +37°C relative humidity is B. Hemorrhagic shock
90%, air speed is 0,2 m/s. The way of heat C. Septicopyemia
emission under these conditions will be: D. Septicemia
A. Radiation E. Viral hepatitis type A
B. Convection 137. There are several groups of molecular
C. Heat conduction mechanisms playing important part in
D. All the ways pathogenesis of insult to cells which contributes
E. Evaporation to the pathology development. What
133. Examination of a 70 year old patient processes are stimulated by proteinic
rrevealed insulin-dependent diabetes. What drug damage mechanisms?
should be administered? A. Phospholipase activation
A. Glibenclamid B. Osmotic membrane distension
B. Parathyroidin C. Enzyme inhibition
C. Insulin D. Lipid peroxidation
D. Mercazolilum E. Acidosis
E. Cortisone 138. A patient takes digoxin for treatment
134. A 59 year old patient is a plant manager. of cardiac insufficiency. What diuretic may
After the tax inspection of his plant he felt increase digoxin toxicity due to the intensified
intense pain behind his breastbone irradiating excretion of K+ ions?
to his left arm. 15 minutes later his condition A. Lisinopril
came to normal. Which of the possible B. Panangine
mechanisms of stenocardia development is C. Siliborum
the leading in this case? D. Spironolactone
A. High catecholamine concentration m E. Hydrochlorothiazide
blood 139. A patient ill with amebiasis was prescribed
B. Coronary atherosclerosis a certain drug. The use of alcohol
C. Functional heart overload together with this drug is contra-indicated
D. Coronary thrombosis because the drug inhibits metabolism of
E. Intravascular aggregation of blood ethyl alcohol. What drug is it?
corpuscles A. Clonidine
135. A 44 year old woman complains of B. Metronidazole
general weakness, heart pain, significant C. Reserpine
increase of body weight. Objectively: moon D. Diazepam

15. E. Aminazine dysentery and was once more infected with
140. While performing an operation in the the same causative agent. What is such
area of axillary crease a surgeon has to define infection form called?
an arterial vessel surrounded by fascicles A. Persisting infection
of brachial plexus. What artery is it? B. Chronic infection
A. A.axillaris C. Recidivation
B. A.profunda brachii D. Superinfection
C. A. vertebralis E. Reinfection
D. A.subscapularis 146. A 30 year old woman has applied a lipstick
E. A. transversa colli with a fluorescent substance for a
141. A patient with nephrotic syndrome has long time. Then she got a limited erythema
massive edemata of his face and limbs. What and slight peeling on her lip border, later
is the leading pathogenelic mechanism of there appeared transversal striae and cracks.
edemata development? Special methods of microscopic examination
A. Rise of hydrodynamic blood pressure of the affected area helped to reveal
B. Lymphostasis sensibilized lymphocytes and macrophages
C. Increase of vascular permeability in the connective tissue: cytolysis. What
D. Increase of lymph outflow type of immunological hypersensitivity was
E. Drop of oncotic blood pressure developed?
142. A patient underwent an operation on A. III type (immune complex cytotoxicity)
account of gall bladder excision that resulted B. I type (reaginic)
in obstruction of Ca absorption through the C. IVtype (cellular cytotoxicity)
bowels wall. What vitamin will stimulate this D. II type (antihody cytotoxicity)
process? E. Granulomatosis
A.C 147. Autopsy of a man who died from
B. B12 the sepsis in his femoral hone revealed
C. D3 phlegmonous inflammation that affected the
D. K marrow, haversian canals and periosteum.
E. PP Under the periosteum there are multiple
143. While studying maximally spiralized abscesses, adjoining soft tissues of thigh also
chromosomes of human karyotype the have signs of phlegmonous inflammation.
process of cell division was stopped in the What pathological process was described?
following phase: A. Chronic henlatogenous osteomielitis
A. Telophase B. Osteoporosis
B. Interphase c. -
C. Anaphase D. Acute hemalogenous osteomyelitis
D. Metaphase E. Osteopetrosis
E. Prophase 148. A patient was diagnosed with autoimmune
144. A patient ill with tuberculosis died hemolitic cytotoxic anemia. What
from progressing cardiopulmonary substances are antigens in II type allergic
decompensation. Autopsy in the area of reactions?
the right lung apex revealed a cavity 5 A. Antibiotics
cm in diameter communicating with lumen B. Hormones
of a segmental bronchus. On the inside C. Serum proteins
cavity walls are covered with caseous D. Modified receptors of cell membranes
masses with epithelioid and Langhans cells E. Inflammation modulators
beneath them. What morphological form of 149. Rats being under stress have muscular
tuberculosis is it? hypertonia and high arterial pressure, high
A. Acute focal tuberculosis glucose concentration in blood and intensified
B. Infiltrative tuberculosis secretion of corticotropin and corticosteroids.
C. Caseous pneumonia In what stress phase are these animals?
D. Acute cavernous tuberculosis A. Exhaustion
E. Tuberculoma B. Terminal
145. A patient recovered from Sonne C. Antishock phase

16. D. Erectile 155. A 38 year old patient with full-blown
E. Shock phase jaundice, small cutaneous hemorrhages,
150. It was proved that a molecule of general weakness and loss of appetite
immature mRNA (precursor mRNA) underwent puncture biopsy of liver. Histological
contained more triplets than amino acids examination revealed disseminated
found in the synthesized protein. The dystrophy, hepatocyte necrosis,
reason for that is that translation is normally Councilman's bodies. Lobule periphery
preceded by: has signs of significant infiltration by
A. Processing lymphocytes, there are also individual
B. Initiation multinuclear
C. Reparation hepatocytes. What is the most
D. Replication probable diagnosis?
E. Mutation A. Acute alcoholic hepatitis
151. A patient who has been treated in a B. Toxic degeneration of liver
neural clinic and has been taking a sedative C. Acute viral hepatitis
for a long time got the following complication: D. Chronic hepatitis
cough, rhinitis, epiphora. What drug E. Miliary hepatic cirrhosis
caused these disturbances? 156. A patient with acute morphine poisoning
A. Sodium bromide was delivered to a hospital. What specific
B. Valerian narcotic antagonist should be chosen in this
C. Phenazepam case?
D. Reserpine A. Unithiol
E. Diazepam B. Paracetamol
152. Examination of a newborn boy's C. Digoxin
genitalia revealed an urethral hiatus that D. Methacin
opens on the undersite of his penis. What E. Naloxone
malformation is it? 157. Autopsy of a man ill with severe
A. Cryptorhidism hypothyroidism revealed that connective tissue,
B. Epispadia organ stroma, adipose and cartilaginous
C. Hermaphroditism tissues were swollen, semitransparent,
D. Monorchism mucus-like. Microscopic examination of tissues
E. Hypospadias revealed stellate cells having processes
153. A patient that entered the admission office with mucus between them. What type of
had the following signs of acute cardiac dystrophy is it?
insuffiency: paleness, acrocyanosis, frequent A. Stromal-vascular carbohydrate
shallow respiration. What drug is B. Strornal-vascular proteinaceous
indicated in this case? C. Parenchymatous adipose
A. Corglycon D. Parenchymatous proteinaceous
B. Adrenaline hydrochloride E. Stromal-vascular adipose
C. Nitroglycerine 158. In order to estimate toxigenity of diphtheria
D. Cordiamin agents obtained from patients the
E. Digitoxin cultures were inoculated on Petri dish with
154. In order to speed up healing of a wound nutrient agar on either side of a filter paper
of oral mucosa a patient was prescribed a strip that was put into the centre and moistened
drug that is a thermostable protein occuring with antidiphtheric antitoxic serum.
in tears, saliva, mother's milk as well as in After incubation of inoculations in agar the
a new-laid hen's egg. It is known that this strip-like areas of medium turbidity were
protein is a factor of natural resistance of an found between separate cultures and the
organism. What is it called? strip of filter paper. What immunological
A. Complement reaction was conducted?
B. Imanine A. Rings precipitation reaction
C. lnterleukin B. Agglutination reaction
D. Interferon C. Precipitation gel reaction
E. Lysozyme D. Coomb's test

17. E. Opsonization reaction caused complete disruption of spinal cord at
159. A patient ill with enteritis accompanied the level of the first cervical segment. What
by massive diarrhea has low water rate in respiration changes will be observed?
the extracellular space, high water rate inside A. No changes will be observed
the cells and low blood osmolarity. What B. It will become infrequent and deep
is such disturbance of water-electrolytic C. Thoracic respiration will be maintained,
metabolism called? diaphragmal respiration will disappear
A. Hyperosmolar hypohydration D. It will come to a standstill
B. Hyperosmolar hyperhydration E. Diaphragmal respiration will be maintained,
C. Osmolar hypohydration thoracic respiration will disappear
D. Hypo-osmolar hyperhydration 165. Systemic arterial pressure of an adult
E. Hypo-osmolar hypohydration dropped from 120/70 to 90/50 mm Hg
160. In course of a preventive examination that led to reflectory vasoconstriction. The
of a miner a doctor revealed changes of vasoconstriction will be maximal in the
cardiovascular fitness which was indicative following organ:
of cardiac insufficiency at the compensation A. Bowels
stage. What is the main proof of cardiac B. Heart
compensation? C. Kidneys
A. Myocardium hypertrophy D. Adrenals
B. Tachycardia E. Brain
C. Cyanosis 166. A pregnant woman was registered in
D. Dyspnea an antenatal clinic and underwent complex
E. Rise of arterial pressure examination for a number of infections.
161. It was found out that some compounds, Blood serum contained IgM to the rubella
for instance fungi toxins and some antibiotics virus. What is this result indicative of?
can inhibit activity of RNA-polymerase. A. Of exacerbation of a chronic disease
What process will be disturbed in a cell in B. Of recurring infection with rubella virus
case of inhibition of this enzyme? C. Of a chronic process
A. Reparation D. The woman is healthy
B. Translation E. Of primary infection
C. Transcription 167. A boy found a spider with the following
D. Replication morphological characteristics: it is 2 cm
E. Processing long, has roundish black abdomen with two
162. As a result of destruction of certain rows of red spots on its dorsal side; four pairs
brainstem structures an animal has lost of jointed limbs are covered with small
its orientative reflexes in response to black hairs. What arthropod is it?
strong photic stimuli. What structures were A. Mite
destroyed? B. Solpuga
A. Posterior tubercles of quadrigeminal plate C. Karakurt spider
B. Anterior tubercles of quadrigeminal plate D. Scorpion
C. Red nuclei E. Tarantula
D. Black substance 168. Examination of a young woman
E. Vestibular nuclei revealed a node-like, soft and elastic
163. Inflammation of the tympanic cavity homogenous tumour of pinkish-white
(purulent otitis media) was complicated colour along the acoustic nerve. The tumour
by inflammation of mammillary process contains cell bundles with oval nuclei.
sockets. What wall of tympanic cavity did Cellular fibrous bundles form rhythmic
the pus penetrate into the sockets through? structures made up by parallel rows of
A. Lateral regularly oriented cells arranged in form
B. Medial of a palisade with cell-free homogenous
C. Anterior zone (Verocay bodies) between them. What
D. Posterior tumour is it?
E. Superior A. Neurinoma
164. A 35 year old man got an injury that B. Ganglioneuroblastoma

18. C. Malignant neurinoma chromophilic and chromophobic. Identify
D. Neuroblastoma this organ:
E. Ganglioneurinoma A. Hypothalamus
169. Two hours after an exam a student had B. Adrenal glands
a blood count done and it was revealed C. Hypophysis
that he had leukocytosis without significant D. Thyroid gland
leukogram modifications. What is the E. Parathyroid gland
most probable mechanism of leukocytosis 174. A patient came to the hospital complaining
development? about quick fatigability and apparent
A. Redistribution of leukocytes in the organism muscle weakness. Examination revealed
B. Deceleration of leukocyte migration to an autoimmune disease that causes disorder
the tissues of functional receptor condition in
C. Leukopoiesis intensification and neuromuscular synapses. What transmitter
deceleration of leukocyte lysis will be blocked?
D. Deceleration of leukocyte lysis A. Noradrenalin
E. Leukopoiesis intensification B. Serotonin
170. If a man has an attack of bronchiospasm C. Glyeine
it is necessary to reduce the effect of D. Dopamine
vagus on smooth muscles of bronchi. What E. Acetylcholine
membrane cytoreceptors should be blocked 175. Microscopic examination of a Gramstained
for this purpose? scrape from patient's tongue
A. M-cholinoreceptors revealed oval, round, elongated chains of
B. β-adrenoreceptors dark-violet gemmating cells. What disease
C. α- and β-adrenoreceptors can be caused by this causative agent?
D. α-adrenoreceptors A. Staphylococcic infection
E. .N-cholinoreceptors B. Streptococcic infection
171. Plasmic factors of blood coagulation C. Diphtheria
are exposed to post-translational modification D. Actinomycosis
with the participation of vitamin K. It E. Candidosis
is necessary as a cofactor in the enzyme 176. A patient ill with chronic gastritis went
system of γ-carboxylation of protein factors for endogastric pH-metry that allowed to
cif blood coagulation due to the increased reveal decreased acidity of gastric juice. It
affinity of their molecules with calcium ions. is indicative of diminished function of the
What amino acid is carboxylated in these following cells:
proteins? A. Parietal exocrinocytes
A. Valine B. Accessory cells
B. Arginine C. Endocrinocytes
C. Phenylalanine D. Cervical cells
D. Glutamic E. Chief exocrinocytes
E. Serine 177. Examination of a 60 year old patient
172. A sensitive neural ganglion consists of revealed hyperglycemia and glucosuria. A
roundish neurocytes with one extension that doctor administered him a medication for
divides into axon and dendrite at some distance internal use. What medication is it?
from the perikaryon. What are these A. Pancreatine
cells called? B. Furosemide
A. Multipolar C. Oxytocin
B. Pseudounipolar D. Glibenclamid
C. Unipolar E. Corglycon
D. Apolar 178. A 6 month old baby ill with bronchitis
E. Bipolar was taken for an X-ray of chest. Apart
173. An endocrinal gland with parenchyma of changes associated with bronchi the X-ray
consisting of epithelium and neural tissue film showed a shadow of thymus gland.
is under morphological examination. Epithelial What might have caused such changes?
trabecules have two types of cells: A. It is caused by thymus inflammation

19. B. It is caused by abnormal position rhinitis and loss of sense of smell for a week.
C. It is caused by neoplastic process Objectively: nasal cavity contains a lot of
D. The above-mentioned condition is a mucus that covers mucous membrane and
normal variant for this age blocks olfactory receptors. In what part of
E. It's the effect of bronchitis nasal cavity are these receptors situated?
179. A 20 year old patient complains of A. Common nasal meatus
general weakness, dizziness, quick fatigability. B. Vestibule of nose
Blood analysis results: Hb- 80 C Median nasal turbinate
g/l. Microscopical examination results: D. Inferior nasal turbinate
erythrocytes are of modified form. This E. Superior nasal turbinate
condition might be caused by: 185. A cardiac electric stimulator was
A. Obturative jaundice implanted to a 75 year old man with heart
B. Acute intermittent porphyria rate of 40 bpm. Thereafter the heart rate
C. Sickle-cell anemia rose up to 70 bpm. The electric stimulator
D. Addison's disease has undertaken the function of the following
E. Hepatocellular jaundice heart part:
180. In course of laparotomy a surgeon A. His' bundle branches
revealed gangrenous lesion of descending B. Sinoatrial node
colon. It was caused by thrombosis of the C. His' bundle fibel's
following artery: D. Purkinje's fibers
A. Dexter colic E. Atrioventricular node
B. Median colic 186. Blood of a patient with presumable
C. Ileocolic sepsis was inoculated into sugar broth.
D. Sinister colic There appeared bottom sediment. Repeated
E. Superior mesenteric artery inoculation into blood agar caused growth
181. In course of a small pelvis operation it of small transparent round colonies
became necessary to ligate an ovarian artery. surrounded by hemolysis zone. Examination
What formation may be accidentally ligated of a smear from the sediment revealed
together with it? gram-positive cocci in form of long chains.
A. Round ligament of uterus What microorganisms are present in blood
B. Urethra ~ of this patient?
C. Uterine tube A. Streptococci
D. Internal iliac vein B. Tetracocci
E. Ureter C. Sarcina
182. A patient has a deep cut wound on the D. Staphylococci
posterior surface of his shoulder in its middle E. Micrococci
third. What muscle might he injured? 187. A patient has low rate of magnesium
A. Anconeus muscle ions that are necessary for affixion of ribosomes
B. Biceps muscle of arm to the endoplasmic reticulum. It is
C Brachial muscle known that it causes disturbance of protein
D. Coracohrachial muscle biosynthesis. At what stage is protein
E. Triceps muscle of arm biosynthesis
183. A patient was admitted to the surgical impaired?
department with suspected inflammation of A. Termination
Meckel`s diverticulum. What part of bowels B. Translation
should be examined in order to discover the C. Amino acid activation
diverticulum in course of an operation? D. Replication
A. Ileum E. Transcription
B. Jejunmum 188. A patient with hypertensic crisis was
C Colon ascendens admitted to the cardiological department,
D. Duodenum he was injected intravenously with an
E. Caecum antihypertensive
184. A 35 year old patient applied to a drug - salt of an alkaline-earth
doctor with complaints about having intense metal. What drug was injected?

20. A. Benzohexamethonium C. Louis-Bar
B. Potassium chloride D. Wiskott-Aldrich
C Sodium hydrocarbonate E. DiGeorge
D. Magnesium sulfate 195. A woman suffering from osteochondrosis
E. Caleium lactate felt acute pain in her humeral articulation
189. Examination of a 35 year old patient that became stronger when she abducted her
revealed high acidity of gastric juice. What shoulder. These symptoms might be caused
receptors should be blocked in order to by damage of the following nerve:
reduce it? A. Dorsal scapular nerve
A. α 1-adrenoreceptors B. Axillary nerve
B. β2-adrenoreceptors C. Subscapular nerve
C. β1 -adrenoreceptors D. Subclavicular nerve
D. α2-adrenoreceptors E. Throracodorsal nerve
E. Histamine 196. A boy has I (I0 I0) blood group and
190. While performing an inguinal canal his sister has IV (IA IB) blood group. What
operation on account of hernia a surgeon blood groups do their parents have?
damaged the canal's contents. What exactly A. III (IB I0) and IV (IA IB)
was damaged? B. II (IA IA) and III (IB I0)
A. Funiculus spermaticus C. II (IA I0) and III (IB I0)
B. Lig. teres uteri D. I (I0 I0) and III (IB I0)
C. - E. I (I0 I0) and IV (IA IB)
D. Lig. inguinale 197. A patient has a cluster of matted
E. Urarchus together dense lymph nodes on his neck.
191. A 3 year old child with fever was given Histological
aspirin. It resulted in intensified erythrocyte examination of a removed lymph
haemolysis. Hemolytic anemia might have node revealed proliferation of reticular cells,
been caused by congenital insufficiency of presense of Reed-Sternberg cells. What disease
the following enzyme: is meant?
A. Glycogen phosphorylase A. Myeloblastic leukosis
B. Glucose 6-phosphate dehydrogenase B. Lyimphogranulomatosis
C. Glycerol phosphate dehydrogenase C. Lymphoblastic leukosis
D. Glucose 6-phosphatase D. Myelocytic leukosis
E. γ-glutamiltransferase E. Lympholcytic leukosis
192. After consumption of rich food a patient 198. A woman underwent an operation on
has nausea and heartburn, steatorrhea. account of extrauterine (tubal) pregnancy.
This condition might he caused by: In course of the operation the surgeon
A. Increased lipase secretion should ligate the branches of the following
B. Bile acid deficiency arteries:
C. Amylase deficiency A. Uterine and superior cystic
D. Disturbed phospholipase synthesis B. Superior cystic and ovarian
E. Disturbed tripsin synthesis C. Uterine and inferior cystic
193. A patient complains of dizziness and D. Uterine and ovarian
hearing loss. What nerve is damaged? E. Inferior cystic and ovarian
A. Vestibulocochlear 199. A specimen stained by Ozheshko
B. Vagus method contains rod-like microorganisms
C. Sublingual stained blue with round terminal
D. Trochlear components stained red. What are these
E. Trigeminus components called?
194. A child was born with cleft palate. A. Capsules
Examination revealed aorta defects and B. Cilia
reduced number of T-Iymphocytes in blood. C. Mesosomas
What immunodeficient syndrome is it? D. Spores
A. Swiss-type E. Flagella
B. Chediak-Higashi 200. A 37 year old patient suffering from

21. obliterating vascular endarteritis of lower
limbs takes daily 60 microgram/kilogram
of phenylin. Because of presentations
of convulsive disorder (craniocerebral
trauma in anamnesis) he was prescribed
phenobarbital. Withholding this drug
caused nasal hemorhage. What is this
complication connected with?
A. Aliphatic hydroxylation of phenobarbital
B. Inhibition of microsomal oxidation in liver
caused by phenobarbital
C. Induction of enzymes of microsomal
oxidation in liver caused by phenobarbital
D. Conjugation of phenylin with glucuronic
acid
E. Oxidative deamination of phenylin