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Restoration of Cleft Lip and Palate




                                   Arun Sharma DDS
    Department of Preventive and Restorative Dentistry, UCSF
                          John Beumer III, DDS, MS
                            Ting Ling Chang, DDS
                     Division of Advanced Prosthodontics, UCLA
*The material in this program of instruction is protected by copyright ©. No
part of this program of instruction may be produced, recorded, or
transmitted by any means, electronic,digital, photographic, mechanical etc.
or by any information storage or retrieval system, without prior permission.
Table of Contents
v    Facial and palatal development
v    Classification of clefts
v    Incidence
v    Etiology
v    Early intervention and counseling
v    Lip repair
v    Palatal repair
v    Growth and development and orthodontic
      treatment
      v    Arch expansion eruption of teeth
      v    Cuspid substitution
Table of Contents
v    Adjunctive surgical procedures
      v    Orthognathic surgery
      v    Pharyngeal flap
      v    Nasal revision
v    Role of obturator prosthesis in children
v    Closing oronasal fistulas and grafting the cleft
v    Stabilizing non-grafted cleft segments
v    Replacing the missing lateral incisor
v    Complete dentures
      v    Role of osseointegrated implants
v    Zygomaticus implants for clefts
v    Overlay removable partial dentures
      v    Role of osseointegrated implants 

Development of Facial Structures




     Drawings depicting the formation of the face from the frontal
     perspective from the fourth week through the eighth week.
From Patten, B. M., 1969
Development of Facial Structures




     Drawings depicting the formation of the face from the frontal
     perspective from the fourth week through the eighth week.
From Patten, B. M., 1969
Development of Facial Structures




     Drawings depicting the formation of the face from the frontal
     perspective from the fourth week through the eighth week.
From Patten, B. M., 1969
Development of Facial Structures




     Drawings depicting the formation of the face from the frontal
     perspective from the fourth week through the eighth week.
From Patten, B. M., 1969
Development of Facial Structures




     Drawings depicting the formation of the face from the frontal
     perspective from the fourth week through the eighth week.
From Patten, B. M., 1969
Cleft lip and palate
  Diagnosis
  v Prenatal   Ultrasound


                             Cleft
Development of Facial Structures




     A.  Median nasal process
     B.  Lateral nasal process
     C.  Maxillary process
Palatal Development
"   Palatogenesis begins 5th week
"   Completed by the 12th week

    Develops from two primordia:
        The primary palate
        The secondary palates
Development of the Palate




                 Section of the head of the embryo
                 late in the eighth week
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Palatal Development




             Graphic summary of palatal fusion
             from the 6th week to the 9th week.
From Patten, B. M., 1969
Classification of Clefts
      v    Cleft lip and alveolus (primary palate)
      v    Cleft of the hard and soft palate (secondary palate)
      v    Combinations of these two




v  Clefts can be bilateral or unilateral
v  Embryologically, anterior clefts differ from posterior clefts
Classification of Clefts
Cleft patients may also present with other
   abnormalities
"   Syndromic forms (15%)
"   Nonsyndromic forms (85%)
Possible combinations of Cleft Lip and Palate
Incidence of Clefting

              " 1 in 700 infants born
              "   Left sided clefts account
                    for 70%

Highest rates in American Indians (1 in 278
births) followed by the Japanese, Maoris,
Chinese, Caucasians and African Americans
(1 in 3,330 births).
Incidence

Cleft lip (with or without cleft palate)
  "   One in every 1000 births
  "   Males affected twice as frequently as
      females
Incidence
      Cleft Palate (with or without Cleft Lip)
"   With or without cleft lip, occurs once in 2500 births
"   Isolated clefts of the palate are more common in females*


                                          *May be due to the
                                          fact that the palatine
                                          processes fuse
                                          about 1 week later
                                          in females than in
                                          males.
Etiology
    v Geneticfactors
    v Environmental factors affecting the
          mother during the first trimester
            v Infection
            v Hormonal      imbalances
            v Poor diet
            v Teratogenic agents*



*Ethanol, folate antagonists, alkylating agents, phenytoin, trimethadione,
valproic acid, benzodiazepines, meprobamate, barbiturates
Treatment Sequence
Lip repair
Palatal repair
Orthodontic treatment
Secondary surgical procedures
     Pharyngeal flaps
     Bone grafting the cleft
     Repairing the nasal deformity
     Orthognathic surgery
Replacing the missing dentition
Treatment Sequence
Early Intervention and Counseling
" Cleft team members assist with the emotional
and social adjustment of the family
" Before leaving the hospital parents should be
able to feed the infant and examine and clean the
cleft
Feeding
A variety of feeding aids have been developed to
aid in feeding the cleft infant.
Genetic Evaluation
v Parental       history
  v Exposure    to teratogens

v Family    history
  v Relativeswith a cleft, lip pits, mental
  retardation, congenital heart disease,
  limb and ocular disorders

v Syndromic
           conditions
v Chromosomal analysis
Team Evaluation
Teams are usually comprised of an audiologist,
geneticist, genetic counselor, nurse
coordinator, oral and maxillofacial surgeon,
orthodontist, otolaryngologist, pediatrician,
pedodontist, plastic surgeon, prosthodontist,
speech pathologist, and social worker.
Role of Prosthodontist
v    Nasoalveolar molding
v    Interim obturators/speech aids
v    Management of edentulous spaces
v    Tx planning restorations for missing teeth and
      correction of tooth size discrepancies
v    Unrepaired cleft palates
Current protocol
        for most major cleft palate teams
Early counseling –prenatal/feeding
Taping or naso-alveolar molding (NAM)
Lip repair
Palate repair
Speech therapy
Pharyngeal flap
Orthodontics
Alveolar cleft graft
Orthognathic surgery
Replacing missing teeth
Lip and nose revision
Presurgical Infant Orthopedic Appliance
                 (PSIO)
l  McNeil 1950, Mylin 1968, Latham 1980
l  To move the alveolar segments closer
    together
Nasoalveolar Molding Appliance
              (NAM)
v  Reduce   the size of the intraoral alveolar cleft
v  Mold and position the surrounding soft
    tissues including the deformed soft tissue
    and cartilage in the cleft nose.
v  Tissue expansion - Columella
Nasoalveolar Molding Protocol
                (Grayson et al, 2001)

Early intervention             <1m
Labor intensive                1-2hrs/wk x 12-24wks
Bilateral cleft                Need 5-6mths molding
Unilateral cleft               Need 3mths molding


v  Alveolar or nasoalveolar molding from birth to 12 wks
v  12-14 wks primary cleft lip repair, nasal, and GPP
        (gingivoperiosteoplasty) in one stage
Nasoalveolar Molding Appliance
                  (NAM)
Result
Ø  Overall improvement in the esthetics of the
    naso-labial complex – Less scarring
Ø  Minimize the extent of surgery and the overall
    number of surgical procedures
Nasoalveolar Molding Appliance (NAM)
                Impressions and casts

a                    b                  c




    a. During impression, infant’s head must in an upright
    position and well supported. b. Impression of silicone
    putty. c. Master cast.
Fabrication of the oral portion of NAM appliance




 l    Cast made from the master cast-wax blockout.
 l    Oral portion of PNAM device made of clear acrylic resin.
 l    Completed device on altered cast. Note posterior
       extension. Excessive length in this area will precipitate
       gagging.
Fabrication of the oral portion of NAM appliance
                            Clear acrylic resin




  Fill the cleft region of the palate and alveolus to
  approximate the contour & topography of an intact
  arch
Fabrication of the oral portion of NAM appliance




l  Diagrammatic representation of the
  subtractions and additions made to NAM
  device in unilateral cleft.
Fabrication of the oral portion of NAM appliance




          v  Fill
                 in cleft with wax
          v  Restore palatal contours
          v  Duplicate cast
Fabrication of the oral portion of NAM appliance
   v  All tissue border must be smooth
   v  Proper contour and finish for tongue space
   v  Limit posterior extension to avoid gagging
Unilateral clefts
  Oral molding portion plus nasal extension




How to retain the oral
                               Adhesive tape
molding appliance?
                                    &
                                 elastics
Unilateral clefts
    Oral molding portion plus nasal extension




v The nasal extension serves as a custom tissue expander to
    correct the flattening nasal deformity It also brings the
    columella into a more midline position.
v Adjustments and additions are performed weekly
v  Note the molding of the nasal cartilage. This projection is
  formed chair side with temporary denture reline materials
Unilateral clefts
      Oral molding portion plus nasal extension




v    Nasoalveolar molding is nearly complete. The columella is
      approaching midline and the nostril on the cleft side is becoming
      more symmetrical.
v    It usually takes 4-6 weeks to attain proper alignment of the alveolar
      cleft segments. At 3 months most patients are ready for surgery
Bilateral clefts




v    In addition to realigning cleft segments a principle advantage of NAM
      in bilateral clefts is elongation of the columella for this often eliminates
      the need for further surgery to elongate this structure.
v    NAM of bilateral clefts consists of three stages
       v    Repositioning the posterior palatal segments and rotating the premaxilla
             into position
       v    Repositioning the alar cartilages
       v    Lengthening the columella
Bilateral clefts




v    Nasoalveolar molding device for bilateral cleft. Nasal
      extensions in position.
v    In bilateral clefts, when the premaxilla attains a
      reasonable position, nasal molding begins. The tips of
      the nasal extension should be kept close together.
      Otherwise the tip of the nose and the columella will be
      excessively widened.
Bilateral clefts




v    As the position and contours of the nose and nasal cartilages
      become more normal, elongation of the columella begins. A
      horizontal strip of soft acrylic resin, the so-called prolabial band, is
      secured to the two nasal extensions. The prolabial band cinches
      the columella and provides length rather than width to the
      columella.
v    This method, when effectively employed, will lengthen the
      columella by 4-7 mm.
Bilateral clefts




Avoid excessive pressure at the lip columella
junction. Doing so may result in ulceration of
this area, compromising the final result.
Before and after NAM




The patient is now ready for surgery. It
usually takes 5-6 months before the tissues
are optimized and the patient is ready for
surgery.

For details see: Brecht L. “Nasoalveolar Molding” in Maxillofacial
Rehabilitation: Prosthodontic and Surgical Management of Cancer-related,
Acquired and Congenital Defects of the Head and Neck. Eds. Beumer J,
Marunick M, Esposito S. Quintessence Pub Co. Chicago, IL, 2011 pp 324-9
Surgical Treatment – Lip Repair
Rule of tens:
    Lip is repaired* when the patient is 10
    weeks old, 10 pounds in weight, with a
    hemoglobin count of 10.


   *The first surgery is usually performed
   at about 3 months. This period may be
   extended to complete NAM, particularly
   in patients with bilateral clefts.
Surgical Treatment – Lip Repair
            A                  B                   C




Modified Le Mesurier surgical technique for lip closure.
A: Development of flaps. B: Flaps prepared for
closure. C: Lip closure.
*Methods of closure were developed based on the nature of the
cleft, the deficiency of the tissues associated with the cleft, and
consequences of scar contracture.
Surgical Treatment – Lip Repair
                    Unilateral cleft




After lip repair. Note the nasal asymetry. The scarring from
the closure of the lip and cleft will impair the development of
normal nasal contours and will probably require correction in
the future.
Surgical Treatment – Lip Repair
                     Bilateral cleft




After lip repair. Note the short columella. The scarring from
the closure of the lip and cleft will impair the development of
normal nasal contours and will require correction in the future.
Complications associated with
            lip repair
v  Multiple additional
    surgeries
v  Less than ideal
    esthetic result
   v  Notethe excessive
     scarring associated
     with this lip closure
     of a bilateral cleft
Surgical Treatment – Palatal Repair
   Timing – Approximately 10 months
           Methods of closure vary
           depending upon:
           v  Extent of the cleft
           v  Availability
                         of tissue
           v  Experience of the surgical team




    Palatal pushback procedure
Surgical Treatment – Palatal Repair
Timing of closure is a matter of opinion. Two
positions:
"   Delayed closure (Zurich approach) – Less inhibition of
         maxillary growth
"   Early closure – Better speech patterns develop early




      Palatal push back and closure procedure
Complications associated with
           palatal repair
v  Shortsoft palate
  resulting in
  velopharyngeal
  insufficiency.
  Speech will be
  hypernasal.
Growth and Development
Growth may be inhibited by:
v  Intrinsictissue deficiencies
v  Quality, amount and location of scar tissue secondary to
        the surgical repairs
Growth during primary and mixed
        dentition stage




Complicating factors
    1. Tight lip
    2. Scar tissue bands in the palate
 These phenomenon result in a deficiency in the
 downward and forward growth of the maxilla
 because of impaired alveolar development.
Growth and Development
Orthodontic treatment – Purposes:
v Expand  the maxilla to correct segment position and crossbite
v Monitor eruption of teeth




 Treatment begins during the mixed dentition stage.
Growth and Development
                           Orthodontic treatment




              Patient with a repaired unilateral cleft.
              Note the arch expansion after one year.
It is vitally important that the maxillary fragments not be allowed to collapse
medially. If they do the tongue will rest on the dentition preventing further
development of the maxilla and impair alveolar development.
Growth and Development
    Orthodontic treatment – Other considerations
    "   Should the missing lateral incisor space be kept open for
    prosthetic replacement with an implant supported restoration or
    closed by eruption and medial movement of the cuspid.




Choice depends upon:
"   Size and shape of the cuspid and the size of the maxilla.
"   If it is decided that the cuspid should come forward, the cleft is grafted after
arch expansion but before the cuspid has moved down into the bony defect.
Growth and Development
  Orthodontic treatment – Other considerations
     "   Should the missing lateral incisor space be kept open for
     prosthetic replacement with an implant supported restoration or
     closed by medial eruption and movement of the cuspid.




v Bilateral clefts we favor canine substitution.
v Unilateral clefts we tend to create space orthodontically
        for placement of an implant
Growth and development during
                adolescence
v  Progressive retrusiveness of the maxilla may
         occur during later growth.
v    The tight lip scar and scar tissue bands in the
         palate impede the forward growth of the maxilla as
         well as the alveolar processes
Adjunctive Surgical procedures
          Orthognathic Surgery




As a result many cleft patient require a maxillary
osteotomy to bring the maxilla down and forward.
Pharyngeal Flaps
v Mostvelopharyngeal discrepancies for cleft patients are
managed surgically, usually with a combination of a palatal
push back and closure procedure (9-18 months).
v However in a small percentage of patients, a superiorly based
pharyngeal flap (3-7 years) is required to enable the patient to
achieve velopharyngeal closure.




             Superiorly based pharyngeal flap.
Pharyngeal Flaps
v  Flaps are raised on the nasal surface of soft palate and
          from the pharyngeal wall. The pharyngeal flap is rotated
          onto the soft palate as shown.
v    As organization and contracture occurs, the soft palate is
          pulled toward the area of normal closure.




                     Superiorly based pharyngeal flap.
Pharyngeal Flaps
"   Closure of the lateral portals is accomplished by contracture
         of lateral pharyngeal walls.
"   Today only a small percentage of patients require flaps




                 Superiorly based pharyngeal flap.
Adjunctive Surgical procedures
           Correcting nasal deformities

Objectives
"  Lengthen the columella
"  Correct deficiencies
        associated with the
        nasal cartilage on the
        cleft side
"  Develop proper contours of
        the nasal tip
Adjunctive Surgical procedures
            Correcting nasal deformities
Objectives
"  Lengthen the columella
"  Correct deficiencies
        associated with the
        nasal cartilage on the
        cleft side
"  Develop proper contours of
        the nasal tip


      This patient has a rather typical
      result after nasal revision surgery
Adjunctive Surgical procedures
      Correcting lip deficiencies
Contour deficiency often occur secondary to scarring
associated with closure. Note the corrections made
in the length of the lip, the lip line and contour.
Adjunctive Surgical procedures
               Correcting lip deficiencies
     Contour and tissue deficiencies occasionally occur
       secondary to scarring associated with closure




Lip switch (Abbey flap)
  "  In this procedure a pedicle flap from the lower lip is used
       to provide more tissue for the upper lip.
Adjunctive Surgical procedures
         Lip switch (Abbey flap)




A typical result. Note the scar on the lower lip
Role of Obturator Prosthesis in Children
v  Clefts of the secondary palate with a paucity of
         residual palatal tissues
v    Poor anesthetic risks
v    Failed pharyngeal flaps
Role of Obturator Prosthesis in Children
 Very short soft palates following surgical repair




   The repaired soft palate is quite short in both of these
   patients and cannot reach and engage the posterior
   pharyngeal wall during velopharyngeal closure. As a result
   speech will be hypernasal and swallowing will be impaired.
Role of Obturator Prosthesis in Children
Failed pharyngeal flap. Why has it failed to restore
speech?




     The pharyngeal flap is too low to effectively interact with
     the lateral pharyngeal walls during velopharyngeal
     closure. As a result speech is hypernasal.
Interim Speech Aids
Soft palate obturators are fabricated in the usual fashion
     (see “Restoration of Soft Palate Defects” FFOFR.org)




  v  Fabricate palatal stent with adequate retention.
  v  Gradually develop the pharyngeal extension.
  v  When the child is has accommodated to the pharyngeal
          extension, develop the obturator portion.
Interim Speech Aids
       The bulb is molded with compound and
                 thermoplastic wax.




v The extensions of the prosthesis are
developed with dental compound and a
thermoplastic wax
v Following processing the contours
and extensions are verified with
pressure indicating paste and/or
disclosing wax (see “Restoration of soft
palate defects” FFOFR.org for details).
Interim Speech Aids
   A completed speech bulb




Obturator prostheses restore velopharyngeal function very
effectively and are well tolerated by the patient. They need
to be remade periodically to account for growth and eruption
of the permanent dentition.
Obturator prosthesis
for failed pharyngeal flaps




              Obturators for failed
              pharyngeal flaps are rarely
              successful because it is
              difficult to extend the
              prosthesis superiorly to
              engage the movable lateral
              pharyngeal walls.
Obturator prosthesis
             for failed pharyngeal flaps
In this patient, the bulb resulted in constant contact with non-
mobile pharyngeal tissues, resulting in hyponasal speech.
The bulb was discarded and the flap removed.



                                  Velopharyngeal function and
                                  normal speech was eventually
                                  restored with a new obturator
                                  prosthesis after the flap had
                                  been removed.
Stabilizing the cleft
     segments after orthodontic treatment
Following orthodontic care
rapid relapse and arch
collapse occurs if the clefts
are not rigidly secured.
This relapse is primarily
due to the stretching of the
midline scar secondary to
surgical closure of the cleft.


  Since the 1950’s two methods have been used:
        v  Fixed partial dentures (1950 – mid 1970’s)
        v  Autogenous     bone grafts (mid 1970’s – present)
Bone Grafting the Cleft
Goals for grafting the cleft
v    To separate the oral and nasal cavities
v    To stabilize the maxillary segments with a bony union
v    To provide normal quality of bone in the alveolus for
          orthodontic movement and support of teeth
v    To provide adequate 3 dimensional bone volume for
          placement of osseointegrated implants
Bone Grafting the Cleft
Timing of grafting
v  Mixed dentition stage is preferred by most
        teams
v    Early grafting (during infancy) of the cleft
        may have a negative affect on the growth
        of the maxilla
Closing oronasal
             fistulas and grafting the cleft




                                  Graft material


Nasal mucosa lining as
well as oral mucosal lining
is required to enclose the
graft material.
Stabilizing non-grafted cleft segments
Fixed partial dentures – From the 50’s thru the mid 70’s the maxillary
fragments were often stabilized with fixed partial dentures.




Full veneer crowns were
required to maximize retention.
Two abutments or more in each
cleft segment is recommended.
Stabilizing non-grafted cleft segments
 Fixed partial dentures – From the 50’s thru the mid 70’s
 the maxillary fragments were often stabilized with fixed
 partial dentures.




In this patient partial veneer crowns were sufficient.
Two abutments were used in each cleft segment.
Stabilizing non-grafted cleft segments
Fixed partial dentures – From the 50’s thru the mid 70’s
the maxillary fragments were often stabilized with fixed partial
dentures.




 In this patient partial veneer crowns were sufficient.
 Double abutments were used in each cleft segment.
Restoring the missing and malformed dentition
        Dental discrepancies of patients with clefts

v  Missing lateral incisors (40%)
v  Maxillary central adjacent to the cleft
        is often undersized
v  Teeth in the premaxilla have
        shortened roots
v  24% have missing premolars
v  More likely to possess super-
        nummery teeth (21%)
v  Teeth adjacent to cleft often present
        with hypocalcified enamel
v  Hypodontia (50%)
Replacing the Missing Lateral Incisor
Implants - Issues
     "   Growth - Skeletal Development
          "    Dental alveolar
          "    Mandible and maxilla
          "    It is advisable to wait until two consecutive cephalometric
               films one year apart show no evidence of growth
     "   Site development
          "    Horizontal and vertical deficiencies usually present
Replacing the Missing Lateral Incisor
    Cuspid substitution vs implants




v Bilateral clefts we favor canine substitution.
v Unilateral clefts we tend to create space orthodontically
        for placement of an implant
Replacing the missing lateral incisor
     Removable Partial Dentures




                    A rotational path of insertion
                    RPD was used to replace
                    the lateral incisor.
Replacing the missing lateral incisor
                                    Implants
Issues
"    Consequences of premature
     placement
      "    Implant will be submerged
            relative to the adjacent teeth
            with the attendant esthetic
            consequences
      "    Less favorable implant
            biomechanics ie. crown root
            ratios

In this patient with a missing lateral incisor, the implant was placed prior to the
completion of growth. As the adjacent natural dentition continued to erupt and
the implant crown appeared submerged relative to the adjacent teeth.
Replacing the missing lateral incisor
                                    Implants
Issues
"    Consequences of premature
     placement
      "    Implant will be submerged
            relative to the adjacent teeth
            with the attendant esthetic
            consequences
      "    Less favorable implant
            biomechanics ie. crown root
            ratios


See “Implants in Growing Children” FFOFR.org for details
Replacing the missing lateral incisor
              Implants




                   At age 21 the implant crown
                   was replaced. Note the
                   discrepancies associated
                   with the the gingival levels
                   of the lateral incisors.
Replacing the Missing Lateral Incisor
Implants - Issues
v Gingival contours are not quite normal
Why?
        Scarring associated with the closure and grafting the
        cleft




Consequences: None. Almost all cleft patients have a low smile line.
Replacing the Missing Lateral Incisor
Note gingival contours.
These are to be expected given
the scarring secondary to the
multiple surgical procedures
necessary to close and graft the
cleft.



          UCSF Data (Sharma and Vargervik, 2006)

       "   24 patients (15 male, 9   "   33 implants placed
                 female)             "   31 implants restored
       "   9 bilateral clefts        "   28 still in function
       "   15 unilateral clefts
Replacing the Missing Lateral Incisor
        Grafting the Cleft and Placing Implants
                  Average age in years (UCSF data)


"    Alveolar cleft bone graft - 14.3
         "    Range (12 – 26) Median 15


"    Implant Placement - 18.1
         "    Range (14 – 28) Median 19
Replacing the Missing Lateral Incisor
Most clefts present with either horizontal or vertical
bone deficiencies and require grafting prior to
implant placement

Implant Placement n = 33

 "   Adequate bone
     15 (45.4%)
 "   Need for regraft
     18 (54.6%)
Replacing the Missing Lateral Incisor
                  Results
    v Implants placed -              33
    v  Implants restored -           31
    v  Implants in function -        28

 *2 implants failed at 2nd stage
 *2 failed in a bilateral cleft after 4 years
 *1 failed in a unilateral cleft after 11 years
Replacing the Missing Lateral Incisor
        Follow up Time (months)




   "    Time since placement - 133.6 mths
           (Range 85 – 166. Median 130)
   "    Time since restored - 129 mths
           (Range 74 – 158, Median 121)
Complete Dentures
     Treatment concepts – Challenges and Difficulties
"   The reduced size of the denture foundation
       area
"   Excessive interarch space
"   Lack of a bony palate
"   Poor alveolar development with shallow
       depth of the palate
"   Scarring from lip closure
"   Scarring in the posterior palatal seal area
"   Presence of oro-nasal fistulas
"   Opposing natural dentition
   "   Misaligned and extruded teeth
"   Soft palate defect

 All these factors negatively impact the retention, stability and
 support provided the complete denture.
Complete Dentures
      Treatment concepts – Challenges and Difficulties




In these three patients note:
"   Reduced size of denture
          foundation area
"   Large oronasal fistulas
"   Little or no alveolar ridges
"   Soft palate defect
Complete Dentures
Treatment concepts – Challenges and Difficulties




In these two patients note:
v  Scarring in the posterior palatal seal area
v  Collapsed maxillary arch segments
Complete Dentures
Treatment concepts – Challenges and
             Difficulties
Result:
v Dramatically compromised stability,
       retention and support
v Bilateral balance is virtually impossible
       to obtain if the opposing arch is dentate

 Most patients cannot masticate effectively with
 these dentures. The primary benefits are improved
 lip contours and esthetics, speech articulation and
 swallowing without nasal leakage.
Complete Dentures
                Making Impressions
Border mold with low fusing compound
  v Posterior palatal seal - single bead
  v Avoid excessive tissue displacement in heavily
     scarred areas
  v Develop the labial flange to support the lip

Corrected impression
  v  Carefully examine for small fistulae
       v  Block out fistulae before making corrected impression
  v Use a polysulfide wash impression material
       v  This material is less likely to fracture and become
           imbedded in undetected fistulae
Complete Dentures
    Vertical Dimension of Occlusion
v  Normal in patients with reasonable
       development of the alveolar processes
v  Interocclusal space is increased in patients
       with very small maxilla and little alveolar
       ridge height
v  Since most patients present with a severe
       Class III jaw relationship the posterior teeth
       are set in crossbite and the anterior teeth
       arranged in an edge to edge relationship
Complete Dentures
                Try in appointment
Esthetics
     Anterior tooth display should be harmonious
     with lip thickness, scarring and contours.
For example:
     A protruding lip scar can be made less
     conspicuous by moving the lateral incisor
     palatally.

Making repeatable centric relation records.
     In patients with a very deficient maxilla it is
     advisable to use processed record bases.
The oral surfaces of the soft palate obturator
          extension must be concave




This complete denture was made for a patient with a partially
repaired cleft lip and palate. Note that the anterior flange is
much thicker than normal. Note the concave oral surface of
the obturator extension to the posterior pharyngeal wall. Flat
or convex oral surfaces may cause gagging or difficulty during
swallowing
Role of Osseointegrated Implants




                              Without the retention and stability provided by
                              implants mastication performance is
                              significantly degraded in edentulous patients
                              with cleft lip and palate fitted with complete
                              dentures. Retention and stability are
                              particularly compromised when the prosthesis
                              extends into the velopharyngeal region.

The addition of implants can have a dramatic impact on patient function and
their placement should be given serious consideration in all such patients.
Role of Osseointegrated Implants 

  Patient presents with a repaired bilateral cleft of
  the lip and palate

Note:
v    The premaxillary
      segment is
      missing
v    The cleft has not
      been
      reconstructed with
      a bone graft
v    The profound
      Class III jaw
      relation
Role of Osseointegrated Implants




v Implants have been placed into each of the remaining posterior
palatal segments and into the anterior region of the mandible.
v The remaining posterior palatal segments move independent of
one another during occlusal function and therefore it is best not to
connect one side to the other with and implant connecting bar.
Implant connecting bar designs




Note:
v    The implant connecting bar does not cross the cleft
v    The bars are designed as an anterior extension
v    When occlusal loads are applied anteriorly, the prosthesis rotates
      around the Hader attachments. The ERA attachments permits the
      prosthesis to be impacted into the anterior denture foundation areas.
Implant connecting bar designs




Both designs are considered implant assisted designs
v    In the maxilla implant support is provided posteriorly but the
      anterior forces are born by the edentulous denture foundation
      areas available for coverage and engagement.
v    In the mandible implant support is provide anteriorly by the
      implant connecting bar but posterior support is provided by the
      primary support areas of the mandible-the retromolar pad and
      the buccal shelf.
Role of Osseointegrated Implants




           Completed prosthesis. Note:
           v  Crossbite
           v  The upper lip has been
               reconstructed with an Abbey
               flap.
Role of Osseointegrated Implants




           v Implants were placed bilaterally
           v The two implants on the left failed.
           v Implant connecting bar was
                  designed to provide retention
                  and stability but they are not
                  the primary means of support.
Zygomaticus implants for clefts




Advantages vs sinus augmentation
v  Fewer surgeries
v  Reduced treatment time
v  No donor site morbidity
Zygomaticus implants for clefts




Issues to consider during
  treatment planning
v    Generally two implants are placed on
      each side.
v    The implants are then splinted
      together with an implant connecting
      bar
Zygomaticus implants for clefts




v  The  implants are splinted together with an implant
    supported connecting bar
v  An removable partial denture supported anteriorly
    by implants and posteriorly by the remaining
    molars
Zygomaticus implants for clefts




l    An overlay RPD was fabricated
      for the maxilla and an overlay
      complete denture for the
      mandible
l    Note the lip support provided by
      the prosthesis
Zygomaticus implants for clefts
a                     b                       c




d                 e            f                    g




a: Edentulous patient with repaired bilateral cleft.
b,c: Four implants have been placed, two conventional and two
       zygomaticus types.
d: Implant supported implant connecting.
e: Prosthesis.
f: Prosthesis in place. Note obturator extension. g: Final result.
Overlay Removable Partial Dentures
Usual clinical findings
    v    Collapsed maxillary arches
    v    Inadequate alveolar development
    v    Excessive inter-occlusal space
    v    Retarded growth of the maxilla
Overlay Removable Partial Dentures
  Purpose of the prosthesis
  "   Restore the missing dentition
  "   Restore the vertical dimension of occlusion
  "   Provide support and contour for the upper lip
Overlay Removable Partial Dentures
Purpose
" Restore the missing dentition
"   Restore the vertical dimension of
          occlusion
"   Provide support and contour for the upper
          lip. Note the thickness and contour
          of the labial flange
Overlay Removable Partial Dentures




Important note:
  "   Before making preliminary or master impressions
      carefully inspect the repaired cleft for fistulas. These
      areas must be carefully blocked out with gauze prior to
      making impressions in order to prevent impacting
      impression materials within the nasal cavity.
Overlay Removable Partial Dentures




" If the interocclusal distance is excessive and the VDO
overclosed, an improved vertical dimension of occlusion can
be established with selective crown placement
Overlay Removable Partial Dentures
Copings on premolars to    These copings will be enclosed
be overlayed protect       within the overdenture.
these teeth from caries.




                           Crown contours are
                           made ideal for the partial
                           overdenture framework.
Overlay Removable Partial Dentures
Note the thickness of
the labial flange.
                        The processed overdenture
                        with the border molded soft
                        palate obturator.




                        These copings are
                        incorporated within the
                        overlay denture.
Overlay Removable Partial Dentures




                      Note:
                      l    Anterior open bite
                      l    Fistulas
                      l    Soft palate defect
Overlay Removable Partial Dentures




v    Remaining teeth covered with gold copings.
v    Tooth tissue junction should be covered with metal as
      opposed to acrylic resin
v    Implants placed in posterior quadrant.
Overlay Removable Partial Dentures
       Border molding the soft palate portion




The obturator portion is developed with compound and thermoplastic
wax. (see “Restoration of soft palate defects” FFOFR.org for details).
Design of the metal framework




"   Note that the tooth tissue junction of all overlaid teeth are covered with
    metal as opposed to acrylic resin. The resin is porous and if you cover
    these areas with this material you will increase the risk of gingival caries
"   Note the metal occlusal surfaces overlaying the implant connecting bar.
    This was done to accommodate for the lack of space between the
    implant connecting bar and the opposing natural dentition.
Overlay Removable Partial Dentures
         Definitive prosthesis.
Overlay Removable Partial Dentures
The premaxilla of this patient
has been removed. Note the
fistula anteriorly. This must
be carefully occluded with
gauze before making
impressions. The maxillary
molars were restored with full
veneer crowns to restore the
VDO to a proper level.

The premolars were covered with copings and splinted to
the first molars. The prosthesis will overlay these copings.
Note the ERA attachments (arrows). These attachments
retain the prosthesis but disengage when incisal forces
are delivered. The axis of rotation is determined by the
distal rests on the first molars bilaterally (arrows).
Overlay Removable Partial Dentures




 This cleft was not bone grafted and therefore the
 individual segments move independent of one another
 exposed to the forces of mastication. Therefore cleft
 segments have not been united prosthodontically.
Overlay Removable Partial Dentures




The prosthesis inserted. Circumferential clasps
have been used. Note the anterior overlay.
Overlay Removable Partial Dentures




The anterior overlay restores the anterior dentition,
provides lip support and obturates the anterior
fistula.
Role of Osseointegrated Implants




Implants can provide cleft patients significant benefit particularly those
restored with an overlay prosthesis. This patient has retained only the
maxillary 2nd molars. The removable partial denture she was wearing
restored the missing dentition and provided support for the lip but lacked
anterior support. Implants provided the needed support.
Role of Osseointegrated Implants




A lateral cephalogram indicated sufficient bone available
anteriorly and implants were place on both sides of the
cleft. Note that the premaxilla had been removed
previously.
Role of Osseointegrated Implants




A “Hader bar” and an “O” ring type attachment were
use to retain the overlay prosthesis.

                       The occlusal surfaces of the
                       mandibular teeth were altered to
                       alleviate occlusal plane
                       discrepancies.
Role of Osseointegrated Implants




The finished prosthesis in position. The posterior mandibular
dentition was restored with a removable partial denture. The
cleft segments had not been grafted together an so they
were not splinted with the implant apparatus.
Obturating residual soft palate
       defects not previously obturated
" Speech will remain hypernasal but leakage during
     swallowing will be reduced.
" Long standing errors in
     articulation remain.
v  Visitffofr.org for hundreds of additional lectures
    on Complete Dentures, Implant Dentistry,
    Removable Partial Dentures, Esthetic Dentistry
    and Maxillofacial Prosthetics.
v  The lectures are free.
v  Our objective is to create the best and most
    comprehensive online programs of instruction in
    Prosthodontics

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Cleft lip and palate

  • 1. Restoration of Cleft Lip and Palate Arun Sharma DDS Department of Preventive and Restorative Dentistry, UCSF John Beumer III, DDS, MS Ting Ling Chang, DDS Division of Advanced Prosthodontics, UCLA *The material in this program of instruction is protected by copyright ©. No part of this program of instruction may be produced, recorded, or transmitted by any means, electronic,digital, photographic, mechanical etc. or by any information storage or retrieval system, without prior permission.
  • 2. Table of Contents v  Facial and palatal development v  Classification of clefts v  Incidence v  Etiology v  Early intervention and counseling v  Lip repair v  Palatal repair v  Growth and development and orthodontic treatment v  Arch expansion eruption of teeth v  Cuspid substitution
  • 3. Table of Contents v  Adjunctive surgical procedures v  Orthognathic surgery v  Pharyngeal flap v  Nasal revision v  Role of obturator prosthesis in children v  Closing oronasal fistulas and grafting the cleft v  Stabilizing non-grafted cleft segments v  Replacing the missing lateral incisor v  Complete dentures v  Role of osseointegrated implants v  Zygomaticus implants for clefts v  Overlay removable partial dentures v  Role of osseointegrated implants 

  • 4. Development of Facial Structures Drawings depicting the formation of the face from the frontal perspective from the fourth week through the eighth week. From Patten, B. M., 1969
  • 5. Development of Facial Structures Drawings depicting the formation of the face from the frontal perspective from the fourth week through the eighth week. From Patten, B. M., 1969
  • 6. Development of Facial Structures Drawings depicting the formation of the face from the frontal perspective from the fourth week through the eighth week. From Patten, B. M., 1969
  • 7. Development of Facial Structures Drawings depicting the formation of the face from the frontal perspective from the fourth week through the eighth week. From Patten, B. M., 1969
  • 8. Development of Facial Structures Drawings depicting the formation of the face from the frontal perspective from the fourth week through the eighth week. From Patten, B. M., 1969
  • 9. Cleft lip and palate Diagnosis v Prenatal Ultrasound Cleft
  • 10. Development of Facial Structures A.  Median nasal process B.  Lateral nasal process C.  Maxillary process
  • 11. Palatal Development " Palatogenesis begins 5th week " Completed by the 12th week Develops from two primordia: The primary palate The secondary palates
  • 12. Development of the Palate Section of the head of the embryo late in the eighth week From Patten, B. M., 1969
  • 13. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 14. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 15. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 16. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 17. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 18. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 19. Palatal Development Graphic summary of palatal fusion from the 6th week to the 9th week. From Patten, B. M., 1969
  • 20. Classification of Clefts v  Cleft lip and alveolus (primary palate) v  Cleft of the hard and soft palate (secondary palate) v  Combinations of these two v  Clefts can be bilateral or unilateral v  Embryologically, anterior clefts differ from posterior clefts
  • 21. Classification of Clefts Cleft patients may also present with other abnormalities " Syndromic forms (15%) " Nonsyndromic forms (85%)
  • 22. Possible combinations of Cleft Lip and Palate
  • 23. Incidence of Clefting " 1 in 700 infants born " Left sided clefts account for 70% Highest rates in American Indians (1 in 278 births) followed by the Japanese, Maoris, Chinese, Caucasians and African Americans (1 in 3,330 births).
  • 24. Incidence Cleft lip (with or without cleft palate) " One in every 1000 births " Males affected twice as frequently as females
  • 25. Incidence Cleft Palate (with or without Cleft Lip) " With or without cleft lip, occurs once in 2500 births " Isolated clefts of the palate are more common in females* *May be due to the fact that the palatine processes fuse about 1 week later in females than in males.
  • 26. Etiology v Geneticfactors v Environmental factors affecting the mother during the first trimester v Infection v Hormonal imbalances v Poor diet v Teratogenic agents* *Ethanol, folate antagonists, alkylating agents, phenytoin, trimethadione, valproic acid, benzodiazepines, meprobamate, barbiturates
  • 27. Treatment Sequence Lip repair Palatal repair Orthodontic treatment Secondary surgical procedures Pharyngeal flaps Bone grafting the cleft Repairing the nasal deformity Orthognathic surgery Replacing the missing dentition
  • 29. Early Intervention and Counseling " Cleft team members assist with the emotional and social adjustment of the family " Before leaving the hospital parents should be able to feed the infant and examine and clean the cleft
  • 30. Feeding A variety of feeding aids have been developed to aid in feeding the cleft infant.
  • 31. Genetic Evaluation v Parental history v Exposure to teratogens v Family history v Relativeswith a cleft, lip pits, mental retardation, congenital heart disease, limb and ocular disorders v Syndromic conditions v Chromosomal analysis
  • 32. Team Evaluation Teams are usually comprised of an audiologist, geneticist, genetic counselor, nurse coordinator, oral and maxillofacial surgeon, orthodontist, otolaryngologist, pediatrician, pedodontist, plastic surgeon, prosthodontist, speech pathologist, and social worker.
  • 33. Role of Prosthodontist v  Nasoalveolar molding v  Interim obturators/speech aids v  Management of edentulous spaces v  Tx planning restorations for missing teeth and correction of tooth size discrepancies v  Unrepaired cleft palates
  • 34. Current protocol for most major cleft palate teams Early counseling –prenatal/feeding Taping or naso-alveolar molding (NAM) Lip repair Palate repair Speech therapy Pharyngeal flap Orthodontics Alveolar cleft graft Orthognathic surgery Replacing missing teeth Lip and nose revision
  • 35. Presurgical Infant Orthopedic Appliance (PSIO) l  McNeil 1950, Mylin 1968, Latham 1980 l  To move the alveolar segments closer together
  • 36. Nasoalveolar Molding Appliance (NAM) v  Reduce the size of the intraoral alveolar cleft v  Mold and position the surrounding soft tissues including the deformed soft tissue and cartilage in the cleft nose. v  Tissue expansion - Columella
  • 37. Nasoalveolar Molding Protocol (Grayson et al, 2001) Early intervention <1m Labor intensive 1-2hrs/wk x 12-24wks Bilateral cleft Need 5-6mths molding Unilateral cleft Need 3mths molding v  Alveolar or nasoalveolar molding from birth to 12 wks v  12-14 wks primary cleft lip repair, nasal, and GPP (gingivoperiosteoplasty) in one stage
  • 38. Nasoalveolar Molding Appliance (NAM) Result Ø  Overall improvement in the esthetics of the naso-labial complex – Less scarring Ø  Minimize the extent of surgery and the overall number of surgical procedures
  • 39. Nasoalveolar Molding Appliance (NAM) Impressions and casts a b c a. During impression, infant’s head must in an upright position and well supported. b. Impression of silicone putty. c. Master cast.
  • 40. Fabrication of the oral portion of NAM appliance l  Cast made from the master cast-wax blockout. l  Oral portion of PNAM device made of clear acrylic resin. l  Completed device on altered cast. Note posterior extension. Excessive length in this area will precipitate gagging.
  • 41. Fabrication of the oral portion of NAM appliance Clear acrylic resin Fill the cleft region of the palate and alveolus to approximate the contour & topography of an intact arch
  • 42. Fabrication of the oral portion of NAM appliance l  Diagrammatic representation of the subtractions and additions made to NAM device in unilateral cleft.
  • 43. Fabrication of the oral portion of NAM appliance v  Fill in cleft with wax v  Restore palatal contours v  Duplicate cast
  • 44. Fabrication of the oral portion of NAM appliance v  All tissue border must be smooth v  Proper contour and finish for tongue space v  Limit posterior extension to avoid gagging
  • 45. Unilateral clefts Oral molding portion plus nasal extension How to retain the oral Adhesive tape molding appliance? & elastics
  • 46. Unilateral clefts Oral molding portion plus nasal extension v The nasal extension serves as a custom tissue expander to correct the flattening nasal deformity It also brings the columella into a more midline position. v Adjustments and additions are performed weekly v  Note the molding of the nasal cartilage. This projection is formed chair side with temporary denture reline materials
  • 47. Unilateral clefts Oral molding portion plus nasal extension v  Nasoalveolar molding is nearly complete. The columella is approaching midline and the nostril on the cleft side is becoming more symmetrical. v  It usually takes 4-6 weeks to attain proper alignment of the alveolar cleft segments. At 3 months most patients are ready for surgery
  • 48. Bilateral clefts v  In addition to realigning cleft segments a principle advantage of NAM in bilateral clefts is elongation of the columella for this often eliminates the need for further surgery to elongate this structure. v  NAM of bilateral clefts consists of three stages v  Repositioning the posterior palatal segments and rotating the premaxilla into position v  Repositioning the alar cartilages v  Lengthening the columella
  • 49. Bilateral clefts v  Nasoalveolar molding device for bilateral cleft. Nasal extensions in position. v  In bilateral clefts, when the premaxilla attains a reasonable position, nasal molding begins. The tips of the nasal extension should be kept close together. Otherwise the tip of the nose and the columella will be excessively widened.
  • 50. Bilateral clefts v  As the position and contours of the nose and nasal cartilages become more normal, elongation of the columella begins. A horizontal strip of soft acrylic resin, the so-called prolabial band, is secured to the two nasal extensions. The prolabial band cinches the columella and provides length rather than width to the columella. v  This method, when effectively employed, will lengthen the columella by 4-7 mm.
  • 51. Bilateral clefts Avoid excessive pressure at the lip columella junction. Doing so may result in ulceration of this area, compromising the final result.
  • 52. Before and after NAM The patient is now ready for surgery. It usually takes 5-6 months before the tissues are optimized and the patient is ready for surgery. For details see: Brecht L. “Nasoalveolar Molding” in Maxillofacial Rehabilitation: Prosthodontic and Surgical Management of Cancer-related, Acquired and Congenital Defects of the Head and Neck. Eds. Beumer J, Marunick M, Esposito S. Quintessence Pub Co. Chicago, IL, 2011 pp 324-9
  • 53. Surgical Treatment – Lip Repair Rule of tens: Lip is repaired* when the patient is 10 weeks old, 10 pounds in weight, with a hemoglobin count of 10. *The first surgery is usually performed at about 3 months. This period may be extended to complete NAM, particularly in patients with bilateral clefts.
  • 54. Surgical Treatment – Lip Repair A B C Modified Le Mesurier surgical technique for lip closure. A: Development of flaps. B: Flaps prepared for closure. C: Lip closure. *Methods of closure were developed based on the nature of the cleft, the deficiency of the tissues associated with the cleft, and consequences of scar contracture.
  • 55. Surgical Treatment – Lip Repair Unilateral cleft After lip repair. Note the nasal asymetry. The scarring from the closure of the lip and cleft will impair the development of normal nasal contours and will probably require correction in the future.
  • 56. Surgical Treatment – Lip Repair Bilateral cleft After lip repair. Note the short columella. The scarring from the closure of the lip and cleft will impair the development of normal nasal contours and will require correction in the future.
  • 57. Complications associated with lip repair v  Multiple additional surgeries v  Less than ideal esthetic result v  Notethe excessive scarring associated with this lip closure of a bilateral cleft
  • 58. Surgical Treatment – Palatal Repair Timing – Approximately 10 months Methods of closure vary depending upon: v  Extent of the cleft v  Availability of tissue v  Experience of the surgical team Palatal pushback procedure
  • 59. Surgical Treatment – Palatal Repair Timing of closure is a matter of opinion. Two positions: "   Delayed closure (Zurich approach) – Less inhibition of maxillary growth "   Early closure – Better speech patterns develop early Palatal push back and closure procedure
  • 60. Complications associated with palatal repair v  Shortsoft palate resulting in velopharyngeal insufficiency. Speech will be hypernasal.
  • 61. Growth and Development Growth may be inhibited by: v  Intrinsictissue deficiencies v  Quality, amount and location of scar tissue secondary to the surgical repairs
  • 62. Growth during primary and mixed dentition stage Complicating factors 1. Tight lip 2. Scar tissue bands in the palate These phenomenon result in a deficiency in the downward and forward growth of the maxilla because of impaired alveolar development.
  • 63. Growth and Development Orthodontic treatment – Purposes: v Expand the maxilla to correct segment position and crossbite v Monitor eruption of teeth Treatment begins during the mixed dentition stage.
  • 64. Growth and Development Orthodontic treatment Patient with a repaired unilateral cleft. Note the arch expansion after one year. It is vitally important that the maxillary fragments not be allowed to collapse medially. If they do the tongue will rest on the dentition preventing further development of the maxilla and impair alveolar development.
  • 65. Growth and Development Orthodontic treatment – Other considerations "   Should the missing lateral incisor space be kept open for prosthetic replacement with an implant supported restoration or closed by eruption and medial movement of the cuspid. Choice depends upon: "   Size and shape of the cuspid and the size of the maxilla. "   If it is decided that the cuspid should come forward, the cleft is grafted after arch expansion but before the cuspid has moved down into the bony defect.
  • 66. Growth and Development Orthodontic treatment – Other considerations "   Should the missing lateral incisor space be kept open for prosthetic replacement with an implant supported restoration or closed by medial eruption and movement of the cuspid. v Bilateral clefts we favor canine substitution. v Unilateral clefts we tend to create space orthodontically for placement of an implant
  • 67. Growth and development during adolescence v  Progressive retrusiveness of the maxilla may occur during later growth. v  The tight lip scar and scar tissue bands in the palate impede the forward growth of the maxilla as well as the alveolar processes
  • 68. Adjunctive Surgical procedures Orthognathic Surgery As a result many cleft patient require a maxillary osteotomy to bring the maxilla down and forward.
  • 69. Pharyngeal Flaps v Mostvelopharyngeal discrepancies for cleft patients are managed surgically, usually with a combination of a palatal push back and closure procedure (9-18 months). v However in a small percentage of patients, a superiorly based pharyngeal flap (3-7 years) is required to enable the patient to achieve velopharyngeal closure. Superiorly based pharyngeal flap.
  • 70. Pharyngeal Flaps v  Flaps are raised on the nasal surface of soft palate and from the pharyngeal wall. The pharyngeal flap is rotated onto the soft palate as shown. v  As organization and contracture occurs, the soft palate is pulled toward the area of normal closure. Superiorly based pharyngeal flap.
  • 71. Pharyngeal Flaps " Closure of the lateral portals is accomplished by contracture of lateral pharyngeal walls. " Today only a small percentage of patients require flaps Superiorly based pharyngeal flap.
  • 72. Adjunctive Surgical procedures Correcting nasal deformities Objectives "  Lengthen the columella "  Correct deficiencies associated with the nasal cartilage on the cleft side "  Develop proper contours of the nasal tip
  • 73. Adjunctive Surgical procedures Correcting nasal deformities Objectives "  Lengthen the columella "  Correct deficiencies associated with the nasal cartilage on the cleft side "  Develop proper contours of the nasal tip This patient has a rather typical result after nasal revision surgery
  • 74. Adjunctive Surgical procedures Correcting lip deficiencies Contour deficiency often occur secondary to scarring associated with closure. Note the corrections made in the length of the lip, the lip line and contour.
  • 75. Adjunctive Surgical procedures Correcting lip deficiencies Contour and tissue deficiencies occasionally occur secondary to scarring associated with closure Lip switch (Abbey flap) "  In this procedure a pedicle flap from the lower lip is used to provide more tissue for the upper lip.
  • 76. Adjunctive Surgical procedures Lip switch (Abbey flap) A typical result. Note the scar on the lower lip
  • 77. Role of Obturator Prosthesis in Children v  Clefts of the secondary palate with a paucity of residual palatal tissues v  Poor anesthetic risks v  Failed pharyngeal flaps
  • 78. Role of Obturator Prosthesis in Children Very short soft palates following surgical repair The repaired soft palate is quite short in both of these patients and cannot reach and engage the posterior pharyngeal wall during velopharyngeal closure. As a result speech will be hypernasal and swallowing will be impaired.
  • 79. Role of Obturator Prosthesis in Children Failed pharyngeal flap. Why has it failed to restore speech? The pharyngeal flap is too low to effectively interact with the lateral pharyngeal walls during velopharyngeal closure. As a result speech is hypernasal.
  • 80. Interim Speech Aids Soft palate obturators are fabricated in the usual fashion (see “Restoration of Soft Palate Defects” FFOFR.org) v  Fabricate palatal stent with adequate retention. v  Gradually develop the pharyngeal extension. v  When the child is has accommodated to the pharyngeal extension, develop the obturator portion.
  • 81. Interim Speech Aids The bulb is molded with compound and thermoplastic wax. v The extensions of the prosthesis are developed with dental compound and a thermoplastic wax v Following processing the contours and extensions are verified with pressure indicating paste and/or disclosing wax (see “Restoration of soft palate defects” FFOFR.org for details).
  • 82. Interim Speech Aids A completed speech bulb Obturator prostheses restore velopharyngeal function very effectively and are well tolerated by the patient. They need to be remade periodically to account for growth and eruption of the permanent dentition.
  • 83. Obturator prosthesis for failed pharyngeal flaps Obturators for failed pharyngeal flaps are rarely successful because it is difficult to extend the prosthesis superiorly to engage the movable lateral pharyngeal walls.
  • 84. Obturator prosthesis for failed pharyngeal flaps In this patient, the bulb resulted in constant contact with non- mobile pharyngeal tissues, resulting in hyponasal speech. The bulb was discarded and the flap removed. Velopharyngeal function and normal speech was eventually restored with a new obturator prosthesis after the flap had been removed.
  • 85. Stabilizing the cleft segments after orthodontic treatment Following orthodontic care rapid relapse and arch collapse occurs if the clefts are not rigidly secured. This relapse is primarily due to the stretching of the midline scar secondary to surgical closure of the cleft. Since the 1950’s two methods have been used: v  Fixed partial dentures (1950 – mid 1970’s) v  Autogenous bone grafts (mid 1970’s – present)
  • 86. Bone Grafting the Cleft Goals for grafting the cleft v  To separate the oral and nasal cavities v  To stabilize the maxillary segments with a bony union v  To provide normal quality of bone in the alveolus for orthodontic movement and support of teeth v  To provide adequate 3 dimensional bone volume for placement of osseointegrated implants
  • 87. Bone Grafting the Cleft Timing of grafting v  Mixed dentition stage is preferred by most teams v  Early grafting (during infancy) of the cleft may have a negative affect on the growth of the maxilla
  • 88. Closing oronasal fistulas and grafting the cleft Graft material Nasal mucosa lining as well as oral mucosal lining is required to enclose the graft material.
  • 89. Stabilizing non-grafted cleft segments Fixed partial dentures – From the 50’s thru the mid 70’s the maxillary fragments were often stabilized with fixed partial dentures. Full veneer crowns were required to maximize retention. Two abutments or more in each cleft segment is recommended.
  • 90. Stabilizing non-grafted cleft segments Fixed partial dentures – From the 50’s thru the mid 70’s the maxillary fragments were often stabilized with fixed partial dentures. In this patient partial veneer crowns were sufficient. Two abutments were used in each cleft segment.
  • 91. Stabilizing non-grafted cleft segments Fixed partial dentures – From the 50’s thru the mid 70’s the maxillary fragments were often stabilized with fixed partial dentures. In this patient partial veneer crowns were sufficient. Double abutments were used in each cleft segment.
  • 92. Restoring the missing and malformed dentition Dental discrepancies of patients with clefts v  Missing lateral incisors (40%) v  Maxillary central adjacent to the cleft is often undersized v  Teeth in the premaxilla have shortened roots v  24% have missing premolars v  More likely to possess super- nummery teeth (21%) v  Teeth adjacent to cleft often present with hypocalcified enamel v  Hypodontia (50%)
  • 93. Replacing the Missing Lateral Incisor Implants - Issues " Growth - Skeletal Development "  Dental alveolar "  Mandible and maxilla "  It is advisable to wait until two consecutive cephalometric films one year apart show no evidence of growth " Site development "  Horizontal and vertical deficiencies usually present
  • 94. Replacing the Missing Lateral Incisor Cuspid substitution vs implants v Bilateral clefts we favor canine substitution. v Unilateral clefts we tend to create space orthodontically for placement of an implant
  • 95. Replacing the missing lateral incisor Removable Partial Dentures A rotational path of insertion RPD was used to replace the lateral incisor.
  • 96. Replacing the missing lateral incisor Implants Issues "  Consequences of premature placement "  Implant will be submerged relative to the adjacent teeth with the attendant esthetic consequences "  Less favorable implant biomechanics ie. crown root ratios In this patient with a missing lateral incisor, the implant was placed prior to the completion of growth. As the adjacent natural dentition continued to erupt and the implant crown appeared submerged relative to the adjacent teeth.
  • 97. Replacing the missing lateral incisor Implants Issues "  Consequences of premature placement "  Implant will be submerged relative to the adjacent teeth with the attendant esthetic consequences "  Less favorable implant biomechanics ie. crown root ratios See “Implants in Growing Children” FFOFR.org for details
  • 98. Replacing the missing lateral incisor Implants At age 21 the implant crown was replaced. Note the discrepancies associated with the the gingival levels of the lateral incisors.
  • 99. Replacing the Missing Lateral Incisor Implants - Issues v Gingival contours are not quite normal Why? Scarring associated with the closure and grafting the cleft Consequences: None. Almost all cleft patients have a low smile line.
  • 100. Replacing the Missing Lateral Incisor Note gingival contours. These are to be expected given the scarring secondary to the multiple surgical procedures necessary to close and graft the cleft. UCSF Data (Sharma and Vargervik, 2006) "   24 patients (15 male, 9 "   33 implants placed female) "   31 implants restored "   9 bilateral clefts "   28 still in function "   15 unilateral clefts
  • 101. Replacing the Missing Lateral Incisor Grafting the Cleft and Placing Implants Average age in years (UCSF data) "  Alveolar cleft bone graft - 14.3 "  Range (12 – 26) Median 15 "  Implant Placement - 18.1 "  Range (14 – 28) Median 19
  • 102. Replacing the Missing Lateral Incisor Most clefts present with either horizontal or vertical bone deficiencies and require grafting prior to implant placement Implant Placement n = 33 "  Adequate bone 15 (45.4%) "   Need for regraft 18 (54.6%)
  • 103. Replacing the Missing Lateral Incisor Results v Implants placed - 33 v  Implants restored - 31 v  Implants in function - 28 *2 implants failed at 2nd stage *2 failed in a bilateral cleft after 4 years *1 failed in a unilateral cleft after 11 years
  • 104. Replacing the Missing Lateral Incisor Follow up Time (months) "  Time since placement - 133.6 mths (Range 85 – 166. Median 130) "  Time since restored - 129 mths (Range 74 – 158, Median 121)
  • 105. Complete Dentures Treatment concepts – Challenges and Difficulties "   The reduced size of the denture foundation area "   Excessive interarch space "   Lack of a bony palate "   Poor alveolar development with shallow depth of the palate "   Scarring from lip closure "   Scarring in the posterior palatal seal area "   Presence of oro-nasal fistulas "   Opposing natural dentition "   Misaligned and extruded teeth "   Soft palate defect All these factors negatively impact the retention, stability and support provided the complete denture.
  • 106. Complete Dentures Treatment concepts – Challenges and Difficulties In these three patients note: "   Reduced size of denture foundation area "   Large oronasal fistulas "   Little or no alveolar ridges "   Soft palate defect
  • 107. Complete Dentures Treatment concepts – Challenges and Difficulties In these two patients note: v  Scarring in the posterior palatal seal area v  Collapsed maxillary arch segments
  • 108. Complete Dentures Treatment concepts – Challenges and Difficulties Result: v Dramatically compromised stability, retention and support v Bilateral balance is virtually impossible to obtain if the opposing arch is dentate Most patients cannot masticate effectively with these dentures. The primary benefits are improved lip contours and esthetics, speech articulation and swallowing without nasal leakage.
  • 109. Complete Dentures Making Impressions Border mold with low fusing compound v Posterior palatal seal - single bead v Avoid excessive tissue displacement in heavily scarred areas v Develop the labial flange to support the lip Corrected impression v  Carefully examine for small fistulae v  Block out fistulae before making corrected impression v Use a polysulfide wash impression material v  This material is less likely to fracture and become imbedded in undetected fistulae
  • 110. Complete Dentures Vertical Dimension of Occlusion v  Normal in patients with reasonable development of the alveolar processes v  Interocclusal space is increased in patients with very small maxilla and little alveolar ridge height v  Since most patients present with a severe Class III jaw relationship the posterior teeth are set in crossbite and the anterior teeth arranged in an edge to edge relationship
  • 111. Complete Dentures Try in appointment Esthetics Anterior tooth display should be harmonious with lip thickness, scarring and contours. For example: A protruding lip scar can be made less conspicuous by moving the lateral incisor palatally. Making repeatable centric relation records. In patients with a very deficient maxilla it is advisable to use processed record bases.
  • 112. The oral surfaces of the soft palate obturator extension must be concave This complete denture was made for a patient with a partially repaired cleft lip and palate. Note that the anterior flange is much thicker than normal. Note the concave oral surface of the obturator extension to the posterior pharyngeal wall. Flat or convex oral surfaces may cause gagging or difficulty during swallowing
  • 113. Role of Osseointegrated Implants Without the retention and stability provided by implants mastication performance is significantly degraded in edentulous patients with cleft lip and palate fitted with complete dentures. Retention and stability are particularly compromised when the prosthesis extends into the velopharyngeal region. The addition of implants can have a dramatic impact on patient function and their placement should be given serious consideration in all such patients.
  • 114. Role of Osseointegrated Implants 
 Patient presents with a repaired bilateral cleft of the lip and palate
 Note: v  The premaxillary segment is missing v  The cleft has not been reconstructed with a bone graft v  The profound Class III jaw relation
  • 115. Role of Osseointegrated Implants v Implants have been placed into each of the remaining posterior palatal segments and into the anterior region of the mandible. v The remaining posterior palatal segments move independent of one another during occlusal function and therefore it is best not to connect one side to the other with and implant connecting bar.
  • 116. Implant connecting bar designs Note: v  The implant connecting bar does not cross the cleft v  The bars are designed as an anterior extension v  When occlusal loads are applied anteriorly, the prosthesis rotates around the Hader attachments. The ERA attachments permits the prosthesis to be impacted into the anterior denture foundation areas.
  • 117. Implant connecting bar designs Both designs are considered implant assisted designs v  In the maxilla implant support is provided posteriorly but the anterior forces are born by the edentulous denture foundation areas available for coverage and engagement. v  In the mandible implant support is provide anteriorly by the implant connecting bar but posterior support is provided by the primary support areas of the mandible-the retromolar pad and the buccal shelf.
  • 118. Role of Osseointegrated Implants Completed prosthesis. Note: v  Crossbite v  The upper lip has been reconstructed with an Abbey flap.
  • 119. Role of Osseointegrated Implants v Implants were placed bilaterally v The two implants on the left failed. v Implant connecting bar was designed to provide retention and stability but they are not the primary means of support.
  • 120. Zygomaticus implants for clefts Advantages vs sinus augmentation v  Fewer surgeries v  Reduced treatment time v  No donor site morbidity
  • 121. Zygomaticus implants for clefts Issues to consider during treatment planning v  Generally two implants are placed on each side. v  The implants are then splinted together with an implant connecting bar
  • 122. Zygomaticus implants for clefts v  The implants are splinted together with an implant supported connecting bar v  An removable partial denture supported anteriorly by implants and posteriorly by the remaining molars
  • 123. Zygomaticus implants for clefts l  An overlay RPD was fabricated for the maxilla and an overlay complete denture for the mandible l  Note the lip support provided by the prosthesis
  • 124. Zygomaticus implants for clefts a b c d e f g a: Edentulous patient with repaired bilateral cleft. b,c: Four implants have been placed, two conventional and two zygomaticus types. d: Implant supported implant connecting. e: Prosthesis. f: Prosthesis in place. Note obturator extension. g: Final result.
  • 125. Overlay Removable Partial Dentures Usual clinical findings v  Collapsed maxillary arches v  Inadequate alveolar development v  Excessive inter-occlusal space v  Retarded growth of the maxilla
  • 126. Overlay Removable Partial Dentures Purpose of the prosthesis " Restore the missing dentition " Restore the vertical dimension of occlusion " Provide support and contour for the upper lip
  • 127. Overlay Removable Partial Dentures Purpose " Restore the missing dentition " Restore the vertical dimension of occlusion " Provide support and contour for the upper lip. Note the thickness and contour of the labial flange
  • 128. Overlay Removable Partial Dentures Important note: " Before making preliminary or master impressions carefully inspect the repaired cleft for fistulas. These areas must be carefully blocked out with gauze prior to making impressions in order to prevent impacting impression materials within the nasal cavity.
  • 129. Overlay Removable Partial Dentures " If the interocclusal distance is excessive and the VDO overclosed, an improved vertical dimension of occlusion can be established with selective crown placement
  • 130. Overlay Removable Partial Dentures Copings on premolars to These copings will be enclosed be overlayed protect within the overdenture. these teeth from caries. Crown contours are made ideal for the partial overdenture framework.
  • 131. Overlay Removable Partial Dentures Note the thickness of the labial flange. The processed overdenture with the border molded soft palate obturator. These copings are incorporated within the overlay denture.
  • 132. Overlay Removable Partial Dentures Note: l  Anterior open bite l  Fistulas l  Soft palate defect
  • 133. Overlay Removable Partial Dentures v  Remaining teeth covered with gold copings. v  Tooth tissue junction should be covered with metal as opposed to acrylic resin v  Implants placed in posterior quadrant.
  • 134. Overlay Removable Partial Dentures Border molding the soft palate portion The obturator portion is developed with compound and thermoplastic wax. (see “Restoration of soft palate defects” FFOFR.org for details).
  • 135. Design of the metal framework " Note that the tooth tissue junction of all overlaid teeth are covered with metal as opposed to acrylic resin. The resin is porous and if you cover these areas with this material you will increase the risk of gingival caries " Note the metal occlusal surfaces overlaying the implant connecting bar. This was done to accommodate for the lack of space between the implant connecting bar and the opposing natural dentition.
  • 136. Overlay Removable Partial Dentures Definitive prosthesis.
  • 137. Overlay Removable Partial Dentures The premaxilla of this patient has been removed. Note the fistula anteriorly. This must be carefully occluded with gauze before making impressions. The maxillary molars were restored with full veneer crowns to restore the VDO to a proper level. The premolars were covered with copings and splinted to the first molars. The prosthesis will overlay these copings. Note the ERA attachments (arrows). These attachments retain the prosthesis but disengage when incisal forces are delivered. The axis of rotation is determined by the distal rests on the first molars bilaterally (arrows).
  • 138. Overlay Removable Partial Dentures This cleft was not bone grafted and therefore the individual segments move independent of one another exposed to the forces of mastication. Therefore cleft segments have not been united prosthodontically.
  • 139. Overlay Removable Partial Dentures The prosthesis inserted. Circumferential clasps have been used. Note the anterior overlay.
  • 140. Overlay Removable Partial Dentures The anterior overlay restores the anterior dentition, provides lip support and obturates the anterior fistula.
  • 141. Role of Osseointegrated Implants Implants can provide cleft patients significant benefit particularly those restored with an overlay prosthesis. This patient has retained only the maxillary 2nd molars. The removable partial denture she was wearing restored the missing dentition and provided support for the lip but lacked anterior support. Implants provided the needed support.
  • 142. Role of Osseointegrated Implants A lateral cephalogram indicated sufficient bone available anteriorly and implants were place on both sides of the cleft. Note that the premaxilla had been removed previously.
  • 143. Role of Osseointegrated Implants A “Hader bar” and an “O” ring type attachment were use to retain the overlay prosthesis. The occlusal surfaces of the mandibular teeth were altered to alleviate occlusal plane discrepancies.
  • 144. Role of Osseointegrated Implants The finished prosthesis in position. The posterior mandibular dentition was restored with a removable partial denture. The cleft segments had not been grafted together an so they were not splinted with the implant apparatus.
  • 145. Obturating residual soft palate defects not previously obturated " Speech will remain hypernasal but leakage during swallowing will be reduced. " Long standing errors in articulation remain.
  • 146. v  Visitffofr.org for hundreds of additional lectures on Complete Dentures, Implant Dentistry, Removable Partial Dentures, Esthetic Dentistry and Maxillofacial Prosthetics. v  The lectures are free. v  Our objective is to create the best and most comprehensive online programs of instruction in Prosthodontics