Ewings Sarcoma

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Ewing’s Sarcoma A Radiation Oncologist’s Perspective Professor Of Radiation Oncology Madras Medical College & Govt. General Hospital Chennai Prof. Mohan Ram R aroi - tn & pondicherry state conference-2006 Chennai 08 Jul’2006

Tributes – Dr. James Ewing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],1866 - 1943

What Prof. Ewing said… ,[object Object],[object Object],[object Object]

Objectives of this talk ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ewing’s Sarcoma - Sites ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Management of Ewing’s Sarcoma ,[object Object],[object Object],[object Object],[object Object],[object Object]

Ewing’s Sarcoma is Radiosensitive ,[object Object],[object Object],[object Object],Kovar et al. Characterization of distinct consecutive phases in non-genotoxic p53-induced apoptosis of Ewing’s tumor cells and the rate limiting role of Caspase-8.Oncogene 2000; 19:4096-4107 Kovar et al. Response of Ewing’s tumor cells to forced and activated p53 expression. Oncogene 2003; 22: 3193-3204

LOCAL TREATMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Emerging Role of Surgery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Is there a Surgical Bias in Literature ? ,[object Object]

Evidence for the Surgical bias ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],Evidence for the Surgical bias

Interpretations for the Radiation Oncologist in decision making ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

INDICATIONS FOR RT ,[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],INDICATIONS FOR RT

SIDE EFFECTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

SIDE EFFECTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

IN THE NEAR FUTURE ,[object Object],[object Object],[object Object],[object Object]

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Ewings Sarcoma

1. Ewing’s Sarcoma A Radiation Oncologist’s Perspective Professor Of Radiation Oncology Madras Medical College & Govt. General Hospital Chennai Prof. Mohan Ram R aroi - tn & pondicherry state conference-2006 Chennai 08 Jul’2006

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19. DOSE & FRACTIONATION

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21. RT in METASTATIC DISEASE

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25. MANY THANKS

Ewings Sarcoma

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