3. Escherichia coli This is the mapped genome of the E. coli bacteria. Note the lac operon.
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7. lac Operon The RNAP binds at the promoter region, then travels along the operator and the coding regions for lacZ, lacY and lacA. However, note that the P/O overlap has a binding site for a repressor . A repressor will “get in the way” of RNAP.
8. lac Operon (with Lactose) RNAP LacZ LacY LacA KEY IDEA: THERE IS LACTOSE! Lactose can be digested!
9. lac Operon (without Lactose) RNAP LacI KEY IDEA: THERE ISN'T LACTOSE! No lactose to digest!
![Escherichia coli (for the curious) ,[object Object],[object Object]](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)