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Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000,...
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  1. 1. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Gastritis
  2. 2. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Out line  Definition of gastritis .Definition of gastritis .  Risk factorsRisk factors  Acute Gastritis(ClinicalAcute Gastritis(Clinical Manifestations)Manifestations)  Chronic Gastritis(ClinicalChronic Gastritis(Clinical Manifestations)Manifestations)  Diagnostic StudiesDiagnostic Studies  TreatmentTreatment
  3. 3. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis • Inflammation of gastric mucosaInflammation of gastric mucosa • One of most common problemsOne of most common problems affecting the stomachaffecting the stomach https://www.google.com.sa/search? hl=ar&site=imghp&tbm=isch&source=hp&biw=1366&bih=673&q=gastritis&oq= gast&gs_l=img.1.3.0l10.3155.6784.0.12965.4.4.0.0.0.0.380.982.2- 1j2.3.0....0...1ac.1.64.img..1.3.976.w-dYoGFUDDM#imgrc=i_SYKM5gctquZM %3A
  4. 4. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis • Result of a breakdown in gastricResult of a breakdown in gastric mucosal barriermucosal barrier • Stomach tissue unprotectedStomach tissue unprotected from autodigestion by HCl acidfrom autodigestion by HCl acid and pepsinand pepsin
  5. 5. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Etiology and PathophysiologyEtiology and Pathophysiology • Risk factorsRisk factors  DrugsDrugs • AspirinAspirin  DietDiet • Alcohol, spicy foodAlcohol, spicy food
  6. 6. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Etiology and PathophysiologyEtiology and Pathophysiology • Risk factors (cont’d)Risk factors (cont’d)  MicroorganismsMicroorganisms • HelicobacterHelicobacter pyloripylori • Staphylococcus organismsStaphylococcus organisms
  7. 7. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Etiology and PathophysiologyEtiology and Pathophysiology • Risk factors (cont’d)Risk factors (cont’d)  Environmental factorsEnvironmental factors • Radiation, smokingRadiation, smoking  Pathophysiologic conditionsPathophysiologic conditions • Burns, renal failureBurns, renal failure  Other factorsOther factors • Psychologic stress, NG tubePsychologic stress, NG tube
  8. 8. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Etiology and PathophysiologyEtiology and Pathophysiology • Risk factors (cont’d)Risk factors (cont’d)  Autoimmune atrophic gastritisAutoimmune atrophic gastritis • Affects fundus and body of stomachAffects fundus and body of stomach • Associated withAssociated with increased risk ofincreased risk of gastric cancergastric cancer • May be link to presence ofMay be link to presence of H. pyloriH. pylori and development of autoimmuneand development of autoimmune chronic gastritischronic gastritis
  9. 9. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Acute GastritisAcute Gastritis Clinical ManifestationsClinical Manifestations • Self-limitingSelf-limiting  Lasts few hours to a few daysLasts few hours to a few days  Complete healing of mucosaComplete healing of mucosa expectedexpected
  10. 10. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Acute GastritisAcute Gastritis Clinical ManifestationsClinical Manifestations  AnorexiaAnorexia  NauseaNausea  VomitingVomiting  Epigastric tendernessEpigastric tenderness  Feeling of fullnessFeeling of fullness  HemorrhageHemorrhage • Common with alcohol abuseCommon with alcohol abuse • May be only symptomMay be only symptom
  11. 11. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. https://www.google.com.sa/search? hl=ar&biw=1366&bih=673&site=imghp&tbm=isch&q=acute+gastritis&revid=940825021&sa=X&ved=0CB0Q1QJqFQoTCOWGg- GOwMgCFUOsPgodIW0Hxw#imgrc=Dpzv5afFJkFh_M%3A
  12. 12. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. http://www.google.com.sa/url? sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=0CAYQjB1qFQoTCKCrrL6SwMgCFchVFAodmPQLyg&url=http%3A %2F%2Fwww.epainassist.com%2Fabdominal-pain%2Fstomach %2Fgastritis&psig=AFQjCNFLcqhfEmJx1q56fXxg3dwkBlesAw&ust=1444849391129943
  13. 13. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Chronic GastritisChronic Gastritis Clinical ManifestationsClinical Manifestations  Symptoms are similar to acuteSymptoms are similar to acute gastritisgastritis  Loss of intrinsic factor can occurLoss of intrinsic factor can occur when acid-secreting cells are lostwhen acid-secreting cells are lost or are nonfunctioningor are nonfunctioning
  14. 14. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. http://www.google.com.sa/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=0CAYQjB1qFQoTCI3KiqWUwMgCFYU3FAod- IoGtA&url=http%3A%2F%2Fprofessional.dimsbd.com%2Fgastrointestinal-disorders%2Fgastritis-and-peptic-ulcer-disease%2Foverview-of- gastritis%2F&psig=AFQjCNGtExucm-oFyezpyU-PjEe_kiu1qA&ust=1444850074314105
  15. 15. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Diagnostic StudiesDiagnostic Studies • Acute gastritisAcute gastritis  Diagnosis most often based onDiagnosis most often based on history of drug and alcohol abusehistory of drug and alcohol abuse • Chronic gastritisChronic gastritis  Diagnosis may be delayed orDiagnosis may be delayed or missed due to nonspecificmissed due to nonspecific symptomssymptoms
  16. 16. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Diagnostic StudiesDiagnostic Studies • Endoscopic examination withEndoscopic examination with biopsybiopsy  Necessary for definitive diagnosisNecessary for definitive diagnosis • Breath, urine, serum, stool, andBreath, urine, serum, stool, and gastric tissue to determinegastric tissue to determine H. pyloriH. pylori
  17. 17. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Diagnostic StudiesDiagnostic Studies • Radiologic studies not helpfulRadiologic studies not helpful • CBCCBC  Confirm presence of anemiaConfirm presence of anemia • Occult blood testOccult blood test
  18. 18. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. GastritisGastritis Diagnostic StudiesDiagnostic Studies • Gastric analysisGastric analysis  Determines achlorhydria (lack of acidDetermines achlorhydria (lack of acid secretion)secretion) • Tissue biopsy with cytologicTissue biopsy with cytologic examinationexamination
  19. 19. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Treatment • AntibioticsAntibiotics – to kill the H. pylori bacteria if found in the digestive tract. • Proton pump inhibitorsProton pump inhibitors – to reduce stomach acid. • Histamine H2 antagonistsHistamine H2 antagonists – to reduce the amount of gastric acid that is released into the digestive tract. • AntacidsAntacids – to neutralize gastric acid.
  20. 20. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. Summary • At the end of presentation we know:  Definition of gastritis .  Risk factors  Acute Gastritis(Clinical Manifestations)  Chronic Gastritis(Clinical Manifestations)  Diagnostic Studies  Treatment
  21. 21. Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved.Copyright © 2007, 2004, 2000, Mosby, Inc., an affiliate of Elsevier Inc. All Rights Reserved. REFERENCES https://en.wikipedia.org/wiki/Gastritis http://www.rightdiagnosis.com/g/gastritis/in http://nursestudy.net/2015/04/17/gastritis-p
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