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Pancreatic
   Islet
What
    is
pancreas??
pancreas
It is a large gland in body that secrete hormones.

The cells that make up of pancreatic islet.

Also known as “islet of langerhans”

It is part of two different organ system
   -Endocrine system
   -Digestive system
Con’t…
There are 3 main cell in the pancreatic islet :

beta cells, which secrete insulin and amylin

alpa cells, which secrete glucagon

delta cells, which secrete somatostatin
LoCation…
Whole a located in the epigastric and left
hypochondriac regions and its right part lies
across the bodies of L1 to L3 vertebrae.

It runs transversely across the posterior
abdominal wall behind the stomach, from the
duodenum to the spleen, sloping upward from
right to left

It is approximately 12.5 – 15cm long and
weighs from 60 – 100gm.
Location..
Structure...




(1) head of pancreas, (2) uncinate process of pancreas, (3)
pancreatic notch, (4) body of pancreas, (5) anterior surface of
pancreas, (6) inferior surface of pancreas, (7) superior margin
of pancreas, (8) anterior margin of pancreas, (9) inferior
margin of pancreas, (10) omental tuber, (11) tail of pancreas,
(12) duodenum
Function of Insulin..
Purpose:-Regulate blood glucose (sugar) in
the normal range.

Action:-Forces many cells of the body to
absorb and use glucose thereby decreasing
blood sugar levels.

Secreted in response- High blood glucose

Secretion inhibit by- low blood glucose
FunCtion oF GLuCaGon…
Purpose:- Assist insulin in regulating blood
glucose (sugar) in the normal range.

Action: Forces many cells of the body to
release (or produce) glucose (increasing blood
sugar).

Secreted in response to - low blood glucose

Secretion inhibit by - high blood glucose
Somatostatin
Purpose:- Regulate the production and
excretion of other endocrine hormones

Action:- produce by hypothalamus to inhibit
insulin, glucagon, gastrin, and other endocrine
hormones

Secreted in response to - High levels of
other endocrine hormones

Secretion inhibit by- Low levels of other
endocrine hormones
summary
Responsible for the endocrine function.

It is a large gland in body that secrete
hormones.

Secreted the major hormones in the endocrine
system
references
Website(google.com)

Ross and wilson

You tube
Pancreatic islet

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Pancreatic islet

  • 1. Pancreatic Islet
  • 2. What is pancreas??
  • 3. pancreas It is a large gland in body that secrete hormones. The cells that make up of pancreatic islet. Also known as “islet of langerhans” It is part of two different organ system -Endocrine system -Digestive system
  • 4. Con’t… There are 3 main cell in the pancreatic islet : beta cells, which secrete insulin and amylin alpa cells, which secrete glucagon delta cells, which secrete somatostatin
  • 5. LoCation… Whole a located in the epigastric and left hypochondriac regions and its right part lies across the bodies of L1 to L3 vertebrae. It runs transversely across the posterior abdominal wall behind the stomach, from the duodenum to the spleen, sloping upward from right to left It is approximately 12.5 – 15cm long and weighs from 60 – 100gm.
  • 7. Structure... (1) head of pancreas, (2) uncinate process of pancreas, (3) pancreatic notch, (4) body of pancreas, (5) anterior surface of pancreas, (6) inferior surface of pancreas, (7) superior margin of pancreas, (8) anterior margin of pancreas, (9) inferior margin of pancreas, (10) omental tuber, (11) tail of pancreas, (12) duodenum
  • 8. Function of Insulin.. Purpose:-Regulate blood glucose (sugar) in the normal range. Action:-Forces many cells of the body to absorb and use glucose thereby decreasing blood sugar levels. Secreted in response- High blood glucose Secretion inhibit by- low blood glucose
  • 9. FunCtion oF GLuCaGon… Purpose:- Assist insulin in regulating blood glucose (sugar) in the normal range. Action: Forces many cells of the body to release (or produce) glucose (increasing blood sugar). Secreted in response to - low blood glucose Secretion inhibit by - high blood glucose
  • 10. Somatostatin Purpose:- Regulate the production and excretion of other endocrine hormones Action:- produce by hypothalamus to inhibit insulin, glucagon, gastrin, and other endocrine hormones Secreted in response to - High levels of other endocrine hormones Secretion inhibit by- Low levels of other endocrine hormones
  • 11. summary Responsible for the endocrine function. It is a large gland in body that secrete hormones. Secreted the major hormones in the endocrine system