2. Introduction:
• Plastic surgeons recognized the potential benefits of treating vascular
lesions with laser in the 1980s.
• It was not until the widespread popularity of laser skin resurfacing in
the following decade that most plastic surgeons jumped in laser use.
• Taking advantage of the public fascination with high-technology, laser
therapy has been partially misrepresented as the state-of-the-art
treatment of a variety of conditions.
3. • Often descried as painless and exaggerated as producing prefect
results, lasers have been misused as a marketing tool to lure patients
away from conventional low-tech techniques that can often produce
equivalent results at significantly lower cost.
• On the other hand there are some conditions such as port-wine stains
that are best treated by laser and the standard of care demands
familiarity with this treatment modality.
4. • The modern plastic surgeon is therefore faced with the dilemma of
trying to sort out which lasers are best for which conditions and
which manufacturer's claims are credible.
5. Laser Physics:
• Fortunately in the 21st century most lasers are used for therapeutic
purposes.
• Although the vast array of available lasers can be confusing , laser
physics are straightforward.
• Light energy can be descried as s series of photons or as a wave
phenomenon.
• The color of light is determined by the wave length which is the
distance between the two successive waves
6. • The human can see only a narrow range of the electromagnetic
spectrum (the visible light), and many lasers produce invisible lights in
the infrared range.
• Molecule or atom in it’s resting state is composed of a nucleus and
circulating electrons. If energy is added to the system, the electrons
become excited and circulate at a higher orbit.
• Eventually an excited electron will fall back to it’s resting orbit
releasing a specific packet of energy- a photon, and the photon has a
wave length specific to that molecule.
• As these photons hit other excited electrons more photons are
released and the light energy increases.
7. • A laser tube has a mirror at each end contains a solid, liquid or gas
medium within it whose electrons are in a resting state. As energy is
added to the system the majority of the electrons become excited
and begin to release photons.
• Only those photons that hit the mirror directly are reflected back into
the lasing media creating more and more photons that travel back
and forth between the mirrors parallel to the tube and the intensity
of the light increases.
• This phenomenon has been descried as Light Amplification by the
Stimulated Emission of Radiation ( LASER )
9. Laser Tissue interaction:
• When the laser strikes on object, a variety of desirable and
undesirable effect may result as the light is reflected, scattered,
transmitted and absorbed.
• Glass and clear liquids will transmit some types of laser light, allowing
photocoagulation through glass slides, the vitreous of the eye, and
water.
• Some lasers will also pass through the epidermis allowing energy to
reach dermal vessels and pigments without disrupting the epidermal
layer.
10. • The depth of penetration depends upon the laser type.
11. • It is the absorbed light that causes the desirable and undesirable
biologic effect.
• Except for Excimer lasers that break chemical bonds, most laser
energy is converted into thermal energy.
• Depending upon the rate of tissue heating, surgical effects include
welding, coagulation, protein denaturation, desiccation and
vaporization.
• Some lasers will indiscriminately target living tissue, while other lasers
will semi-selectively target a specific chromophore such as
oxyhemoglobin, melanin, and tattoo pigmentation
12. • Selective photothermolysis describes the ability of laser to target
blood vessels or pigment without harming the surrounding dermis or
epidermis.
• It is generally safer to deliver cutaneous laser light in pulses rather
than as a continuous beam, as the interval between pulses allows the
tissue to cool before the heat is transferred to the surrounding
dermis.
• Pulsed lasers respect the thermal relaxation time of dermal vessels
(the time to dissipate the heat absorbed during a laser pulse)
13. Ablative laser:
• Lasers that nonspecifically destroy the tissue can be used to remove
skin lesions or remove layers of the skin, usually with minimal blood
loss because the dermal vessels are coagulated as the tissue
vaporized.
• CO2 laser light is absorbed by intracellular water which vaporizes the
tissue as the water turns to steam.
14. Vascular lesion laser:
• The fact that oxyhemoglobin absorbs green and yellow light has
spawned a variety of lasers appropriate for treating dermal vessels.
• Yellow light has become the preferred color with the yellow dye argon
laser because the oxyhemoglobin absorption peak at 577 nm.
• The high energy/shot duration pulse causes vascular disruption as the
blood rapidly heats up and expands.
• The diode laser can also be used(800nm), as the light is absorbed by
oxyhemoglobin and melanin.
15. Pigmented lesion laser:
• Pigmented lesion lasers target melanin.
• Benign pigmented lesions such as lentigines,
18. and nevus of ota
All these lesions may improve with laser treatment.
19. • Congenital nevai will also lighten with laser but this is controversial.
• Laser is unlikely to increase the risk of malignant transformation, but
may delay the diagnosis of a changing nevus by masking the colour
change associated with melanoma.
20. Photodynamic therapy:
• The use of light-activated drugs to treat acne and other skin
conditions currently is best represented by topical 5-aminolevulinic
acid, (Levulan).
• .
21. • The compound is metabolized by sebaceous gland in to porphyrins.
• The acne bacteria itself also produces porphyrin, and the use of blue,
green or red light stimulates the production of oxygen free radicals
that destroy the bacteria and suppress the sebaceous gland activity
25. Vascular lesions:
• Hemangiomas:
• Hemangiomas are the most common benign tumors of infancy.
• 60% occur at head and neck region
• 70% of hemangiomas regress satisfactorily but 30% of patients will
have cosmetically significant deformity.
• Laser is a potentially useful option in several settings.
• The pulsed yellow dye laser may be very useful for very early
hemangiomas, ulcerated hemangiomas, and regressed hemangiomas
that still contain vascular pigmentation or visible ectatic vessels
27. • The laser only penetrates about one millimeter into the skin and
therefore, it is most effective for small flat hemangiomas.
• Parents should be advised that multiple laser treatment may be
necessary every two to four weeks during the proliferative phase as
hemangiomas will often exhibit temporary regression followed by
rebound growth.
• Laser therapy can be discontinued when the hemangioma finally
enters a permanent state of regression.
• Topical anesthetic cream is desirable to reduce both the patient and
parents discomfort.
28. • Laser treatments are not effective for already bulky or subcutaneous
hemangiomas as the light will not penetrate deeply enough to
produce noticeable improvement.
• Hemangiomas can be excruciatingly painfull specially when located in
the perineal region, there has been some success with pulsed yellow
dye laser treatment of these hemangiomas, with some babies
showing significant pain relief within 24 to 48 hours probably due to
coagulation of sensitive nerve endings within the wound.
30. • Faster healing has also been reported with laser although the
mechanism for this observation is unclear.
• Hemangiomas that have regressed well enough to avoid the need for
surgical excision may have residual ectatic vessels that will improve
with pulsed dye laser.
• Larger telangiectasias may also respond to simultaneous
sclerotherapy and laser treatment.
31. Capillary vascular malformation:
• Port wine stains tend to darken with age as the dilated dermal
capillaries and venules enlarge with time.
• The involved areas may also show textural changes and soft tissue
hypertrophy and hyperplastic vascular nodule, pyogenic granulomas
may develop with problematic bleeding, again the pulsed dye laser
(595 nm) is the treatment of choice.
• Children respond better than teenagers because the immature
vessels are more photosensitive and treatment can be offered
beginning in infancy.
32. • Parents should be advised that multiple (at least six to eight)
treatments are needed as recommended for cumulative benefit, and
that it is extremely rare for any capillary vascular malformation to
completely disappear.
• Associated bruising from the laser lasts for about two weeks, the
gradual lightening of the vascular pigmentation may last for at least
two months.
• Topical anesthetic cream is helpful on the trunk and extremity but
children with large facial port-wine stain will be better treated under
a general anesthesia.
33. • Metal eye shields for periorbital laser therapy.
34. Venous malformations:
• Venous malformations consist of dilated clusters of varicose veins and
treatment options include laser photocoagulation, sclerotherapy and
surgical debulking.
• Small superficial veins may improve with pulsed dye laser therapy but
usually the energy pulse is too brief and the vessels are too large to
show significant benefit.
• Longer energy delivery with a continuous wave laser such as KTP or
neodymium:YAG laser can result in significant heat absorption and
vascular destruction with a significant shrinkage in the size of
malformation
35. • Large venous malformation can be debulked by surgery or by using the
fiber of a KTP or neodymium-YAG laser as a contact tip laser scalpel.
• Laser scalpel Laser scalpel
36. • Endovenous laser photocoagulation with the assistance of ultrasonic
guidance is now a therapeutic option for cosmetic varicose veins as
well as congenital venous malformations.
39. Lymphatic malformations:
• Cutaneous vesicles resembling tiny water blisters represents the
dermal component of a lymphatic malformation.
• Usually associated with a more extensive subcutaneous component.
40. • Problematic lymphatic oozing from ulcerated vesicles can be
palliatively treated with the CO2 laser which is absorbed by water.
• The heat of the absorbed laser energy may cause a desirable fibrosis
at the site of leaking lymphatics.
• This treatment is palliative but can be repeated for unresectable
lesions.
41. Venolymphatic malformations
• Similar to lymphatic malformation but associated with additional
venous component.
• The cutaneous component may appear as tiny purple vesicle or
crusting scabs (angiokeratoma).
• Commonly associated with Klippel-Trenaunay syndrome.
• Vesicles are more responsive to coagulation by continuous laser than
the yellow dye pulsed laser, therefore the KTP is more effective.
• Crusting lesions can be tangentially shaved, then compressed with a
glass slide to control bleeding before being lased.
43. Telangiectasia/Rosacea
• Represents undulating dilated dermal vessels that course through the
dermal layer.
• They appear discontinuous because they are visible near the surface
and then disappear as they dive into the deeper dermis.
• Associated with U/V damage or rosacea, they respond to a variety of
vascular lesion lasers.
• They respond to IPL therapy after multiple sessions.
46. Pyogenic granuloma:
• Shiny nodule of proliferative vascular tissue covered by a fragile
epidermal layer.
• they have an annoying propensity to bleed when ulcerated.
• Can occur at any age but more common in children and pregnant
women.
• May result from minor trauma.
47. • Treated by tangential shave excision followed by laser.
photocoagulation of the dermal base.
• A glass slide is used to compress the bleeding base and a continuous
laser such as KTP will pass through the glass to coagulate the
proliferative lesion
49. Spider angiomas:
• Superficial vascular lesions characterized by central feeding arteriole
and radiating braches.
• Compression will blanch the lesion which will then readily reappear at
the center and expands outwards after the pressure is released.
• Pulsed yellow dye laser is excellent way to coagulate the entire lesion
51. Cherry angiomas:
• Macular or papular cherry-colored nodules commonly seen in adult
skin.
• Range in size from punctate lesions to several millimeters.
• Laser is effective in treatment.
52. Spider veins/Varicose veins:
• Dilated leg spider veins may respond to a variety of lasers but it is
usually most efficient to remove the larger veins first.
• Endovenous laser therapy using a 810 nm diode laser has become a
good treatment alternative.
• Pulsed dye or diode laser will penetrate in to the deep dermis to treat
residual spider veins as well as the peripheral blush that is often seen
after sclerotherapy of large vessels.
54. Adenoma sebaceum/tuberous sclerosis:
• Patients with tuberous sclerosis will develop firm pink nodules in a
butterfly pattern across their cheek and nose with additional
involvement of chin and forehead.
• Neither adenomatous nor sebaceous, these lesions are more
accurately are angiofibromas.
• Vaporization with a defocused CO2 laser appears to be much more
efficient in improving the skin surface contour.
• The heat from laser coagulates the exposed dermis making the
procedure virtually bloodless.
56. Pigment lesions:
• Melanin absorbs light in the ultraviolet to near infrared range,
therefore a wide variety of lasers have been used to target benign
melanocytic lesions.
• Pulse lasers are safer and less likely to cause scarring than continuous
lights.
• Shorter wavelengths will treat epidermal pigmentations, while long
waves are more effective for dermal pigmentation.
• Epidermal lesions such as freckles, solar letigines, and labial
melanocytic macules respond to green pulse dye, while deeper
dermal pigmented lesions such as café au lait spots, nevus of ota may
respond to longer wavelength such as ruby, alexandrite and diode.
57. • Freckles
• Solar lentigines
• Labial melanocytic macules
58. Neurofibromatosis:
• Large plexiform neurofibromas should be excised by standard surgical
techniques.
• Patients who request removal of hundreds of small neurofibromas
may be well served by CO2 laser destruction.
• The laser in slightly defocused mode can vaporize and coagulate small
neurofibromas.
• Treatment is palliative
60. Syringioms:
• Benign tumors of eccrine origin most commonly found in periorbital area.
• CO2 laser results in rapid obliteration of these lesions usually without
recurrence.
• After laser treatment
61. Cylindroma
• Nodular benign dermal tumor thought to be of primitive sweat gland
origin.
• Large disfiguring nodules involving the face and scalp (so-called
turban tumor) can be excised or vaporized using CO2 laser to reduce
associated blood loss.
• The procedure is only palliative.
63. Actinic keratosis
• Patients with extensive actinic changes of their facial skin and lower
lip are candidates for laser skin resurfacing.
• It may be better tolerated than topical 5-fluorouracil therapy or a
surgical lower lip vermilion shave.
• CO2 laser can readily vaporize the epidermis and papillary dermis
allowing the regeneration of healthier skin.
64. • The laser will also readily vaporize the vermilion of the lower lip,
which heals remarkably well in 2 to 3 weeks.
• Although painful until the vermilion mucosa regenerates, it avoids the
need for a mucosal advancement flap
66. Verruca Vulgaris:
• CO2 laser has been most commonly used to vaporize the involved
areas particularly when there are multiple lesions that may make
surgical excision difficult.
• To reduce the risk of viral transmission to medical personal, it is
advisable to sharply excise the bulk of the lesion and then vaporize
the base.
67. Rhinophyma
• Characterized by hypertrophic sebaceous glands and marked
thickening and distortion of the dermis layer of the nose.
• Can be effectively vaporized with the CO2 laser with minimal
bleeding.
• The end result is superior to shave excision and skin grafting.
68. Epidermal nevi:
• While possessing no significant malignant risk, can cause severe
disfigurement, as the nevi thicken and create a verrucous surface
texture.
• Epidermal
nevi
70. • Palliative options include tangential shave excision, dermabresion,
and full thickness excision.
• CO2 laser provides a fast and clean way to improve the surface
texture with minimal bleeding.
• For relatively thin but raised epidermal nevi the laser appear to
vaporize the nevus along a clean and consistent dermal plain.
• Thicker nevi may require multiple laser passes.
• Wounds are covered with topical antibiotic ointment and are left to
re-epithelialize
72. Hair removal:
• The basic principal of laser hair removal is to use light energy to
destroy the hair root for permanent hair reduction.
• This requires a deeply penetrating wave length that must reach the
dermal papilla without adversely destroying the surrounding dermis.
• Most hair removal lasers target melanin and deeply penetrating lasers
such as diode, alexndrite and YAG lasers are most effective on
patients with dark and fair skin.
74. • Patients with light or grey hair are poor candidates for these lasers
even with efforts to darken the hairs with carbon particles.
75. • Patients should be advised that multiple treatment sessions are the
routine and that hair removal is not necessary permanent.
76. Tattoo removal:
• Tattoos are created by pigments or foreign matter that is embedded
in dermis layer of the skin for decorative purposes or therapeutic as in
case of nipple/areola reconstruction.
• Historically the tattoos have been removed by abrasion of the skin
until the deepest pigment has been removed, this routinely shiney
atrophic scars at best and hypertrophic and keloid scars in
unfavorable areas.
Decorative Tattoo for nipple
tattoo reconstruction
77. • CO2 laser is simply a high-tech method of dermabrasion and offers
little advantage over mechanical dermabrasion.
78. • The advent of Q-switched ruby, YAG and Alexandrite lasers offers the
possibility of tattoo removal without clinically apparent scarring.
• Pigment granules are fragmented into smaller particles that are then
phagocytized by macrophages.