Dr Rajeev K Varshney updated on the key points on Global open breeding informatics initiative project; Translating genomics information for crop improvement, Genomic resources and cost-effective genotyping platforms are made available with precise phenotyping, user friendly pipelines and decision support tools developed for use in Breeding programs.
Similar to Research Program Genetic Gains (RPGG) Review Meeting 2021: Update on Global open breeding informatics initiative By Dr Rajeev K Varshney (20)
2. Translating genomics information
for crop improvement
Genomic resources and
cost-effective genotyping
platforms are made
available with precise
phenotyping
User friendly pipelines and
decision support tools
developed for use in
Breeding programs
Genomic
selection
MAS
3. GOBii goals
• Provide an open-source database to manage
genotyping data from multiple genotyping
platforms for any crop
• Provide user interfaces to query across datasets
by samples and markers
• Provide analyses and visualizing tools to support
data curation and breeding decisions
• Develop solutions to integrate GOBii with
adjacent breeding management, sample tracking,
vendor systems and downstream tools
• Provide consulting to manage data, and
implement genomic and marker-assisted
selection
• Develop a global community of developers, data
curators, molecular breeders and breeders with a
common interest to transform breeding
4. MID Breeders
Manish Roorkiwal
Prasad Bajaj Chaitanya SarmaS Sivasubramani
Principal Investigator
Rajeev K Varshney
Curators
Developers
Himabindu Kudapa Anilkumar V Roma R Das
IT Specialist
Pradyut Modi
Chickpea Breeder
S Srinivasan
Sorghum Breeder
C Bharadwaj
GOBII Team @ ICRISAT
M Govindaraj
Abhishek Rathore Anu ChitikineniSantosh Deshpande
Biometrician Genomicist Senior Manager
5. GOBii and System IntegrationGOBii-HTPG
Integration
GOBii Instances
@ICRISAT
GOBii Tools
6. GOBii community, collaboration and training
Workshop by the EiB with GOBii and HTPG
Uganda (November 8th-10th, 2017)
We are building a global community of
knowledge through workshops, hackathons
and cross-training to transform breeding
http://cbsugobii05.tc.cornell.edu/wordpress/
7. Continuous needs assessment, prioritization
and feedback
• Release and onsite deployment of genomic database, Genomics Open Source Breeding Informatics
Initiative (GOBii)- v2.1 (Sep, 2019), improved versions of the GOBii v2.2 (March 7, 2020), v2.2.1 (July,
2020); and the latest version v2.2.2 (Oct, 2020)
• Data loaded on GOBii instances for ICRISAT mandate crops including peanut, pigenpea and pearl
millet, in addition to chickpea and sorghum.
• Uploaded a total of 16.32 billion datapoints for 5524 chickpea samples (three projects (3171 samples
& 3,941,492 marker, 195 samples & 19,574,878 markers and 2158 samples & 2014 markers)). One more
dataset of ~2800 samples with >2k markers being curated for uploading on GOBii database.
• Curation of additional 250 datasets for chickpea, groundnut and pigeonpea for uploading on GOBii.
• Data on 23 pigeonpea MABC populations; 9 historical data files on groundnut.
• Developed QC panel for chickpea and sorghum using WGS and high-density genotyping data on
parental lines from ICRISAT breeding programs.
• Chickpea QC panel with 14 SNPs developed and ready for deployment. Preliminary data on chickpea
QC panel for >17K datapoints (~370 samples and 48 markers) for QC development and >21K datapoints
(1504 samples and 14 markers) representing more than 90 breeding population from ICRISAT chickpea
breeding program uploaded after curation and available for breeder to make selection.
8. • Provided continuous feedback and inputs for FlapJack MABC
and F1 Ped Ver module.
• GOBii decision support tool, Genomic Selection - Galaxy
developed and is being deployed for establishing genomic
prediction models and line selection in the breeding program.
• Successfully deployed and tested GOBii instance for SBDM-
NARS partners
• MABC cases in sorghum using FlapJack
• Genomic prediction in chickpea, closely linked with ICAR
chickpea breeding programs (IARI, IIPR, AICRP)
• Genomic prediction in sorghum, closely linked with ICAR
sorghum breeding programs (IIMR, AICRP, SAUs)
Visualization tools and use cases
9. Kelly Robbins/ Liz Jones
Director
Monica
Fransiscus
Administrator
Liz Jones
Project
Manager
Yaw Nti-
Addae
Lead
Developer
Josh Lamos-
Sweeny
Software
Developer
Phil Glaser
UI Developer
Kevin Palis
DB Developer
Raza Syed
DB Developer
Angel Villahoz-
Baleta
Scientific
Programmer
Star Gao
Breeding
Informatics
Dave
Mathews
Consultant
• Susan McCouch
• Ed Buckler
• Jean-Luc Jannink
• Lukas Mueller
• Mark Sorrels
• Qi Sun
• Mike Olsen
• Susanne Dresigacker
• Rajeev K. Varshney
• Tobias Kretzschmar
• R. Mauleon
Principle Investigators
• M. Roorkiwal
• H. Kudapa
• A. Rathore
• R. Das
• V. Anil Kumar
• P. Bajaj
• S. Sivasubramani
• S. Chaitanya
• S. Deshpande
• P. Gaur/ H Gandhi
• S Srinivasan
• A. Kumar/ M Govindaraj
• P. Modi
ICRISAT
• J. C. Ignacio
• V. M. Juanillas
• J. Detras
• A. M. Raquel
• V. Calaminos
• N. Alexandrov
• M. Krakkainen
• M. Van den Berg
• Josh Cobb
• G. Kotch
IRRI
• V. J. Ulat
• K. Dreher
• X. Zhang
• R. Shrestha
• C. Ayada
• J. Riis-Jacobsen
• S. J. Hearne
• U. Rosyara
CIMMYT
SAB
• Steve Rounsley
• Julie Ho
• Nirav Merchant
• Rebecca Doerge
• Amy L Williams
• Dorian Garrick
• Jan Erik Backlund
• Dan Stanzione
• Dean Podlich