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Conus Medullaris
&
Cauda Equina Syndrome
By: Ismah Haron
06/08/20141
‘Leg weakness is flaccid and areflexic
not spastic and hyperreflexic’
06/08/20142
Source: Walter B. Greene. Netter's Orthopaedics 1st ed. 2006
Source:
Keith L. Moore and Anne Agur. Essential Clinical Anatomy, 3rd Edition
06/08/20143
06/08/20144
Etiology
 Trauma
- Fracture, subluxation
- Penetrating trauma
 Herniated disc
- 90% at L4-L5 and L5-S1
 Spinal stenosis
- Developmental abnormality
- Degenerative disease
Picture from: Walter B. Greene. Netter's Orthopaedics 1st ed. 2006
06/08/20145
 Neoplasm
- Primary (schwannoma, paraganglioma)
- Metastatic (intracranial, lung, breast
and renal cell ca)
 Inflammations and infections
- Paget disease, epidural abscess
- Pyogenic and non pyogenic
Picture from: http://emedicine.medscape.com/
 Iatrogenic
- Misplaced pedicle screw, laminar hooks
- Continuous spinal anesthesia
06/08/20146Picture from: http://www.science-art.com
Conus medullaris syndrome Cauda equina syndrome
Vertebral level L1-L2 L2-sacrum
Spinal level Sacral cord segment and roots Lumbosacral nerve roots
Presentation Sudden and bilateral Gradual and unilateral
Radicular pain Less severe More severe
Low back pain More Less
Motor strength Symmetrical, less marked
hyperreflexic distal paresis of
LL, fasciculation
More marked asymmetric
areflexic paraplegia,
atrophy more common
Reflexes Ankle jerks affected Both knee and ankle jerks
affected
Sensory Localized numbness to perianal
area, symmetrical and bilateral
Localized numbness at
saddle area, asymmetrical,
unilateral
Sphincter
dysfunction
Early urinary and fecal
incontinence
Tend to present late
Impotence Frequent Less frequent
06/08/20147
Conus Medullaris vs. Cauda Equina Syndromes
06/08/20148
Illustration of saddle anesthesia;
- The S5, S4, and S3 nerves provide sensory
innervation to the rectum, perineum, and
inner thigh.
Source:
Journal of the American Academy of Orthopaedics Surgeons,
http://www.jaaos.org
 Radiology – MRI
 Laboratory – FBC, ESR
 Needle electromyography of the bilateral external
anal sphincter muscles
 Lumbar puncture
06/08/20149
Investigation
06/08/201410
Sagittal and axial CT scans of
thoracolumbar spine
demonstrating an L4 burst
fracture with retropulsion of
bone into the spinal canal
Source: Harrop, J. S., G. E. Hunt Jr, et al. (2004). "Conus medullaris and cauda
equina syndrome as a result of traumatic injuries: management principles."
Neurosurgical Focus 16(6): 1-23.
06/08/201411
Source: Harrop, J. S., G. E. Hunt Jr, et al. (2004). "Conus medullaris and cauda
equina syndrome as a result of traumatic injuries: management principles."
Neurosurgical Focus 16(6): 1-23.
MRI image shows
compression of the
distal lumbar and
sacral nerve rootles
06/08/201412
Sagittal MRI images
demonstrating large
central disc extrusion
at L5-S1 (arrows) with
compression on the
cauda equina.
Source: Levis, J. T. (2009). "Cauda
equina syndrome." Western Journal of
Emergency Medicine 10(1): 20.
 Discectomy - 1 2
 Laminectomy
06/08/201413
Method to Relieve Cord Compression
06/08/201414
Source: http://www.spinesurgeon.co.uk/media/lumbar-corpectomy.jpg
Corpectomy
 Important predictor of recovery
- The extent of perineal or saddle sensory deficit
 Patients with unilateral deficits have a better prognosis than
patients with bilateral deficits
 Females and patients with bowel dysfunction have been
reported to have worse outcomes postoperatively
06/08/201415
Prognosis
Source:
- Shaw A, Anwar H, Targett J, Lafferty K. Cauda equina syndrome versus saddle embolism. Ann R Coll Surg Engl. Sep 2008;90(6):W6-8.
- O'Laughlin SJ, Kokosinski E. Cauda equina syndrome in a pregnant woman referred to physical therapy for low back pain. J Orthop Sports Phys Ther.
Nov 2008;38(11):721.
THANK YOU
Other references:
- http://emedicine.medscape.com/article/1148690
- Oxford handbook of clinical medicine
- Oxford handbook of clinical surgery
- Apley’s consice system of orthopaedics and fractures 3rd edition
06/08/201416

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Conus medullaris and cauda equina syndrome

  • 1. Conus Medullaris & Cauda Equina Syndrome By: Ismah Haron 06/08/20141 ‘Leg weakness is flaccid and areflexic not spastic and hyperreflexic’
  • 2. 06/08/20142 Source: Walter B. Greene. Netter's Orthopaedics 1st ed. 2006 Source: Keith L. Moore and Anne Agur. Essential Clinical Anatomy, 3rd Edition
  • 4. 06/08/20144 Etiology  Trauma - Fracture, subluxation - Penetrating trauma  Herniated disc - 90% at L4-L5 and L5-S1  Spinal stenosis - Developmental abnormality - Degenerative disease Picture from: Walter B. Greene. Netter's Orthopaedics 1st ed. 2006
  • 5. 06/08/20145  Neoplasm - Primary (schwannoma, paraganglioma) - Metastatic (intracranial, lung, breast and renal cell ca)  Inflammations and infections - Paget disease, epidural abscess - Pyogenic and non pyogenic Picture from: http://emedicine.medscape.com/
  • 6.  Iatrogenic - Misplaced pedicle screw, laminar hooks - Continuous spinal anesthesia 06/08/20146Picture from: http://www.science-art.com
  • 7. Conus medullaris syndrome Cauda equina syndrome Vertebral level L1-L2 L2-sacrum Spinal level Sacral cord segment and roots Lumbosacral nerve roots Presentation Sudden and bilateral Gradual and unilateral Radicular pain Less severe More severe Low back pain More Less Motor strength Symmetrical, less marked hyperreflexic distal paresis of LL, fasciculation More marked asymmetric areflexic paraplegia, atrophy more common Reflexes Ankle jerks affected Both knee and ankle jerks affected Sensory Localized numbness to perianal area, symmetrical and bilateral Localized numbness at saddle area, asymmetrical, unilateral Sphincter dysfunction Early urinary and fecal incontinence Tend to present late Impotence Frequent Less frequent 06/08/20147 Conus Medullaris vs. Cauda Equina Syndromes
  • 8. 06/08/20148 Illustration of saddle anesthesia; - The S5, S4, and S3 nerves provide sensory innervation to the rectum, perineum, and inner thigh. Source: Journal of the American Academy of Orthopaedics Surgeons, http://www.jaaos.org
  • 9.  Radiology – MRI  Laboratory – FBC, ESR  Needle electromyography of the bilateral external anal sphincter muscles  Lumbar puncture 06/08/20149 Investigation
  • 10. 06/08/201410 Sagittal and axial CT scans of thoracolumbar spine demonstrating an L4 burst fracture with retropulsion of bone into the spinal canal Source: Harrop, J. S., G. E. Hunt Jr, et al. (2004). "Conus medullaris and cauda equina syndrome as a result of traumatic injuries: management principles." Neurosurgical Focus 16(6): 1-23.
  • 11. 06/08/201411 Source: Harrop, J. S., G. E. Hunt Jr, et al. (2004). "Conus medullaris and cauda equina syndrome as a result of traumatic injuries: management principles." Neurosurgical Focus 16(6): 1-23. MRI image shows compression of the distal lumbar and sacral nerve rootles
  • 12. 06/08/201412 Sagittal MRI images demonstrating large central disc extrusion at L5-S1 (arrows) with compression on the cauda equina. Source: Levis, J. T. (2009). "Cauda equina syndrome." Western Journal of Emergency Medicine 10(1): 20.
  • 13.  Discectomy - 1 2  Laminectomy 06/08/201413 Method to Relieve Cord Compression
  • 15.  Important predictor of recovery - The extent of perineal or saddle sensory deficit  Patients with unilateral deficits have a better prognosis than patients with bilateral deficits  Females and patients with bowel dysfunction have been reported to have worse outcomes postoperatively 06/08/201415 Prognosis Source: - Shaw A, Anwar H, Targett J, Lafferty K. Cauda equina syndrome versus saddle embolism. Ann R Coll Surg Engl. Sep 2008;90(6):W6-8. - O'Laughlin SJ, Kokosinski E. Cauda equina syndrome in a pregnant woman referred to physical therapy for low back pain. J Orthop Sports Phys Ther. Nov 2008;38(11):721.
  • 16. THANK YOU Other references: - http://emedicine.medscape.com/article/1148690 - Oxford handbook of clinical medicine - Oxford handbook of clinical surgery - Apley’s consice system of orthopaedics and fractures 3rd edition 06/08/201416

Editor's Notes

  1. Dermatomes
  2. Local pain is generally a deep, aching pain resulting from soft-tissue and vertebral body irritation. Radicular pain is generally a sharp, stabbing pain resulting from compression of the dorsal nerve roots
  3. Diagnosis based on history & pe findings EMG-could help in predicting prognosis and monitoring recovery