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SymptomManagementin
TheEmergencyDepartment
Ryan Cheng
2/8/18
PalliativeCare
Oneshoulddieproudly
whenitisnolonger
possibletoliveproudly.
Friedrich Nietzsche
TheProblem
Pain Delirium Dyspnoea Bladder and
Bowel
Nausea and
Vomiting
PainManagement:OpiateNaรฏve
IV
Morphine 2.5-5mg q5min
Fentanyl 25-50mcg q5min
SC
Morphine 2.5-5mg q10min
Fentanyl 25-50mcg q10min
PainManagement:OpiateTolerant
โ€ข Need to convert existing PO doses of opiate analgesics to IV/SC equivalent
โ€ข Breakthrough should be charted as 1
12
to 1
6
of calculated equivalence
Opioid Parenteral Oral
morphine 10 mg IV/SC 30 mg
oxycodone 10 mg IV/SC 20 mg
hydromorphone 1.5 to 2 mg IV/SC 6 mg
fentanyl 100 to 150 micrograms IV/SC โ€“
methadone Discuss with palliative care
buprenorphine 400 micrograms IV/SC 800 micrograms sublingual
codeine โ€“ 240 mg
tapentadol โ€“ 100 mg
tramadol 100 mg intravenous 150 mg
PainManagement:OpiateTolerant
Patient is on Oxycodone 60mg BD
โ€ข Daily dose = 120mg
โ€ข Equivalent = Morphine 180mg PO
โ€ข SC equivalent = 60mg in 24hrs
โ€ข PRN range 1
12
to 1
6
= 5mg to 10mg morphine SC PRN
Opioid Parenteral Oral
morphine 10 mg IV/SC 30 mg
oxycodone 10 mg IV/SC 20 mg
PainManagement
โ€ข Re-review analgesic use in 24 hours (if still in EDโ€ฆ) to recalculate requirements
โ€ข Donโ€™t forget adjuncts!
โ€ข Paracetamol
โ€ข NSAIDs
Delirium
โ€ข Haloperidol 1mg SC q1h PRN โ€“ max 5mg
โ€ข Midazolam 1-2mg SC q1h PRN
DyspnoeaandSecretions
โ€ข Opiate or benzos
โ€ข Sit patient up, or in desired position for comfort
โ€ข High flow oxygen (even in the absence of hypoxia)
โ€ข Humidified air
โ€ข Permit patient to hold mask to face rather than securing to minimize claustrophobia
โ€ข Secretions: buscopan 20mg q1h SC PRN โ€“ max 80mg
BladderandBowelCare
โ€ข Consider catheterization/urodome if patient is unable to mobilize to the toilet
โ€ข Remember, the Lotus room does not have facilities or readily accessible nursing staff!
โ€ข Patients without family/NOK present do not qualify for use of the lotus room
โ€ข If not imminently dying, consider laxatives for management of constipation secondary to
opiate use
Nauseaand Vomiting
โ€ข Metoclopramide
โ€ข Shouldnโ€™t be used if pro-kinetic effect can worsen symptoms, i.e. bowel obstruction
โ€ข Haloperidol
โ€ข Ondansetron
โ€ข If intracranial cause, consider dexamethasone 4-8mg PO/SC OD
โ€ข Refractory nausea with multiple multimodal agents
โ€ข Dexamethasone 4mg PO OD
OtherComplications
โ€ข Seizures โ€“ midazolam
โ€ข Acute airway obstruction/stridor
โ€ข Dexamethasone 16mg PO/IV/SC stat
โ€ข Adrenaline nebs
โ€ข SVC obstruction or spinal cord compression
โ€ข Dexamethasone 16mg PO/IV/SC stat
AcuteHaemorrhage
โ€ข If active treatment is appropriate, treat as usual
โ€ข If catastrophic bleeding secondary to a terminal event (i.e. arterial erosion), active treatment
and medications unlikely to be administered in time
โ€ข Remain with the patient to provide the comfort of physical presence
โ€ข If not for active treatment, but not imminently dying
โ€ข Morphine and midazolam
ExamplePRNRecap(OpiateNaรฏve)
Morphine 2.5-5mg SC q10min
Midazolam 1-2mg SC q1h
Haloperidol 1mg SC q1h โ€“ max 5mg
Buscopan 20mg SC q1h โ€“ max 80mg
Metoclopramide 10mg SC q8h
Consider Paracetamol/NSAIDs
BitsandPieces
โ€ข Palliative care consultation available 24hrs
โ€ข After hours = pall care consultant (theyโ€™re really nice!)
โ€ข Flags patient for PC follow up
โ€ข Need to liaise with PC, if lotus room is desired
โ€ข Nobody should have to die alone
โ€ข Comfort from physical presence should not be underestimated
โ€ข Pre-empt dealing with the aftermath
โ€ข Liaise with SW early
โ€ข Have difficult discussions/breaking bad news with other
team members present to reiterate and explain
Hopedoesnotlieina
wayoutbutinaway
through.
Robert Frost

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Palliative care in the emergency department

  • 3. TheProblem Pain Delirium Dyspnoea Bladder and Bowel Nausea and Vomiting
  • 4. PainManagement:OpiateNaรฏve IV Morphine 2.5-5mg q5min Fentanyl 25-50mcg q5min SC Morphine 2.5-5mg q10min Fentanyl 25-50mcg q10min
  • 5. PainManagement:OpiateTolerant โ€ข Need to convert existing PO doses of opiate analgesics to IV/SC equivalent โ€ข Breakthrough should be charted as 1 12 to 1 6 of calculated equivalence Opioid Parenteral Oral morphine 10 mg IV/SC 30 mg oxycodone 10 mg IV/SC 20 mg hydromorphone 1.5 to 2 mg IV/SC 6 mg fentanyl 100 to 150 micrograms IV/SC โ€“ methadone Discuss with palliative care buprenorphine 400 micrograms IV/SC 800 micrograms sublingual codeine โ€“ 240 mg tapentadol โ€“ 100 mg tramadol 100 mg intravenous 150 mg
  • 6. PainManagement:OpiateTolerant Patient is on Oxycodone 60mg BD โ€ข Daily dose = 120mg โ€ข Equivalent = Morphine 180mg PO โ€ข SC equivalent = 60mg in 24hrs โ€ข PRN range 1 12 to 1 6 = 5mg to 10mg morphine SC PRN Opioid Parenteral Oral morphine 10 mg IV/SC 30 mg oxycodone 10 mg IV/SC 20 mg
  • 7. PainManagement โ€ข Re-review analgesic use in 24 hours (if still in EDโ€ฆ) to recalculate requirements โ€ข Donโ€™t forget adjuncts! โ€ข Paracetamol โ€ข NSAIDs
  • 8. Delirium โ€ข Haloperidol 1mg SC q1h PRN โ€“ max 5mg โ€ข Midazolam 1-2mg SC q1h PRN
  • 9. DyspnoeaandSecretions โ€ข Opiate or benzos โ€ข Sit patient up, or in desired position for comfort โ€ข High flow oxygen (even in the absence of hypoxia) โ€ข Humidified air โ€ข Permit patient to hold mask to face rather than securing to minimize claustrophobia โ€ข Secretions: buscopan 20mg q1h SC PRN โ€“ max 80mg
  • 10. BladderandBowelCare โ€ข Consider catheterization/urodome if patient is unable to mobilize to the toilet โ€ข Remember, the Lotus room does not have facilities or readily accessible nursing staff! โ€ข Patients without family/NOK present do not qualify for use of the lotus room โ€ข If not imminently dying, consider laxatives for management of constipation secondary to opiate use
  • 11. Nauseaand Vomiting โ€ข Metoclopramide โ€ข Shouldnโ€™t be used if pro-kinetic effect can worsen symptoms, i.e. bowel obstruction โ€ข Haloperidol โ€ข Ondansetron โ€ข If intracranial cause, consider dexamethasone 4-8mg PO/SC OD โ€ข Refractory nausea with multiple multimodal agents โ€ข Dexamethasone 4mg PO OD
  • 12. OtherComplications โ€ข Seizures โ€“ midazolam โ€ข Acute airway obstruction/stridor โ€ข Dexamethasone 16mg PO/IV/SC stat โ€ข Adrenaline nebs โ€ข SVC obstruction or spinal cord compression โ€ข Dexamethasone 16mg PO/IV/SC stat
  • 13. AcuteHaemorrhage โ€ข If active treatment is appropriate, treat as usual โ€ข If catastrophic bleeding secondary to a terminal event (i.e. arterial erosion), active treatment and medications unlikely to be administered in time โ€ข Remain with the patient to provide the comfort of physical presence โ€ข If not for active treatment, but not imminently dying โ€ข Morphine and midazolam
  • 14. ExamplePRNRecap(OpiateNaรฏve) Morphine 2.5-5mg SC q10min Midazolam 1-2mg SC q1h Haloperidol 1mg SC q1h โ€“ max 5mg Buscopan 20mg SC q1h โ€“ max 80mg Metoclopramide 10mg SC q8h Consider Paracetamol/NSAIDs
  • 15. BitsandPieces โ€ข Palliative care consultation available 24hrs โ€ข After hours = pall care consultant (theyโ€™re really nice!) โ€ข Flags patient for PC follow up โ€ข Need to liaise with PC, if lotus room is desired โ€ข Nobody should have to die alone โ€ข Comfort from physical presence should not be underestimated โ€ข Pre-empt dealing with the aftermath โ€ข Liaise with SW early โ€ข Have difficult discussions/breaking bad news with other team members present to reiterate and explain