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Cognitive therapy for command hallucinations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Command hallucinations ,[object Object],[object Object],[object Object],[object Object],[object Object]
Common findings ,[object Object],[object Object],[object Object]
Principles of cognitive therapy ,[object Object],[object Object]
Principles of cognitive therapy ,[object Object],[object Object],[object Object],[object Object]
Hypothesis ,[object Object],[object Object],[object Object]
Resistance Compliance Appeasement behaviour Conviction of power Distress  Depression Frequency,  loudness content
Method ,[object Object],[object Object],[object Object],[object Object],[object Object]
Design of the trial ,[object Object],[object Object],[object Object],[object Object],[object Object]
Procedure ,[object Object],[object Object],[object Object],[object Object]
Measures ,[object Object],[object Object],[object Object]
Measures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Measures ,[object Object],[object Object],[object Object],[object Object]
TREATMENT AS USUAL ,[object Object],[object Object],[object Object]
CTCH GROUP ,[object Object],[object Object],[object Object],[object Object],[object Object]
CTCH  Know How? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Sample description – consort
Types of commands ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Commands &Compliance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical &Demographic patterns
Psychopathology
Psychopathology
Scores
Impact of CTCH-Compliance Both: p<0.0001 Ctch –6mth: p<0.036 Ctch –12: p<0.001 V.C.SCORES
Drug’s role?? ,[object Object],T.A.U C.T.C.H
Beliefs / topography / distress POWER vpd MALEVOLENCE bavq OMNISCIENCE bacq DISTRESS psyrats FRQUENCY psyrats LOUDNESS psyrats NEGATIVE CONTENT psyrats DEPRESSION cdss CONTROL psyrats
+ Impact of CTCH
power and compliance ,[object Object],V.P.D  Pre-rx Compliance scores Post –rx Compliance scores Post rx compliance Normal  & intervention
Distress & depression
Topography of voices -outcome
Correlations??? ,[object Object]
Psychotic Symptoms PANSS+ PANSS- G.PSYPATH CBT 12 CBT 6 T.A.U 6 T.A.U 12 PANSS+ T.A.U 12 PANSS- G.PSYPATH P<0.001 FOLLOW UP AT 6 & 12 MONTHS
HALLUCINATIONS DELUSIONS ANXIETY TENSION GUILT VOLITION PROBLEMS ATTENTION PROBLEMS PANSS+ & MEDS
Reduction in compliance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Change in beliefs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Validity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Qualitative feedback ,[object Object],[object Object]
Limits ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Real world relevance

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CBT for Command Hallucinations

Editor's Notes

  1. By challenging key beliefs about the power of commanding voices,
  2. in relation to the voice, and beliefs about the voice’s identity, power, purpose or meaning and the likely consequences of obedience or resistance. The Beliefs About Voices Questionnaire (BAVQ; Chadwick &amp; Birchwood, 1995 ; Chadwick et al , 2000 ) measures key beliefs about auditory hallucinations, including benevolence, malevolence and two dimensions of relationship with the voice: ‘engagement’ and ‘resistance’
  3. structured interview format to obtain from each client a description of all those commands and associated behaviours (compliance or resistance) within the previous 8 weeks The assessor then interviewed either a key-worker or relative to corroborate the information, and where there was a discrepancy, recorded the worst behaviour mentioned by either party behavioural scientist (K.R.) was employed 6 months post-trial to check the record of commands and associated compliance and resistance behaviours obtained from interview against the case notes (1) neither appeasement nor compliance; (2) symbolic appeasement, i.e. compliant with innocuous and/or harmless commands; (3) appeasement, i.e. preparatory acts or gestures; (4) partial compliance with at least one severe command; (5) full compliance with at least one severe command
  4. , with regard to the components of power, including strength, confidence, respect, ability to inflict harm, superiority and knowledge
  5. are four core dysfunctional beliefs that define the client–voice (social rank) power relationship:
  6. collaborative empiricism and Socratic dialogue, the therapist seeks to engage the client to question, challenge and undermine the power beliefs, then to use behavioural tests to help the client gain disconfirming evidence against the beliefs. These strategies are also used to build clients’ alternative beliefs in their own power and status, and finally, where appropriate, to explore the origins of the schema so clients have an explanation for why they developed those beliefs about the voice in the first place. These interventions are designed to enable the individual to break free of the need to comply or appease, and thereby reduce distress. The CTCH was given in line with the protocol developed by M.B. and P.T. by one of the authors (S.B.) – a clinical psychologist experienced in cognitive therapy and supervised in CTCH by A.M., M.B. and P.T. A behavioural scientist (K.R.) All sessions achieved 4 or more on each subsection on a scale where 0=inadequate, 6=excellent and 4=good. The scale is divided into general (agenda, feedback, understanding, interpersonal effectiveness and collaboration) and specific (guided discovery, focus on key cognitions, choice of intervention, homework and quality of intervention). The treatment protocol is described fully in Byrne et al ( 2003 ).
  7. The test of each hypothesis focused on the interaction term. It is also of interest to determine if there are general trends across time in both groups (e.g. reduction in compliance) tested using the ‘time’ main-effect term of the GLIM analysis. To test whether the intervention was effective, baseline v. 6 months measures were used; for maintenance of any treatment effects, baseline v. 12 months measures were used. Exact probability values were calculated.
  8. A total of 224 referrals were screened, from which 69 patients were identified as being eligible for the study and were invited to participate. Of these, 31 refused consent, leaving a sample of 38 consenting to randomisation ( Fig. 1 ). The sample included 24 men and 14 women, with a mean age of 35.5 years (s.d. 10.4). The sample was drawn from a broad ethnic base, including 27 (71%) White, 6 (16%) Black Caribbean and 4 (14%) other/South Asian patients. The clinical and demographic characteristics of the treatment and control groups are shown in Table 2 . Those refusing consent did not differ from the participants on available data (gender, age, duration of illness)
  9. These findings were unaffected when change in neuroleptic dose over time was used as covariate. However, within the TAU group, the rise in neuroleptic dose was correlated ( r =0.46, NS) with reducing compliance; and in the CTCH group, the reduction in medication use was correlated ( r =0.63, P &lt;0.01) with reducing compliance. At baseline and follow-up, there was no correlation between medication dose and compliance or voice power
  10. Evil disposition towards others CTCH, cognitive therapy for command hallucinations; TAU, treatment as usual; VPD, Voice Power Differential Scale; BAVQ, Beliefs About Voices Questionnaire; PSYRATS, Psychotic Symptom Rating Scale; CDSS, Calgary Depression Scale for Schizophrenia
  11. Our theory predicts that it is the focus on the power of the voice that is responsible for the observed reductions in compliance behaviour. This was tested by comparing the two groups on compliance at follow-up and entering voice power (VPD) as covariate, predicting that the covariate will render the treatment effect non-significant. At 6 months, the two groups were significantly different in compliance (CVS: F =7.3, P =0.011); however, when power was entered as covariate, the difference was no longer significant ( F =2.6, NS). At 12 months, the groups were significantly different ( F =9.8, P =0.004), but again this disappeared when controlling for VPD at 12 months ( F &lt;1, NS).
  12. Distress (PSYRATS). Intensity of distress fell significantly in the CTCH group at 6 months but not in the control group ( F interaction =5.3, P =0.03). By 12 months distress levels in the groups were no longer different ( F =2.7, NS) but there was an overall lessening of distress over this period ( F =4.2, P =0.05). Depression (CDSS). There was no change in depression scores with time ( F &lt;1) and no interaction with treatment group ( F interaction =1.3, NS). However, by 12 months, depression had risen significantly in the TAU but not in the CTCH group ( F interaction =7.3, P =0.012). The baseline score of the whole sample (s.d. 6.4) indicates moderate depression ( Addington et al , 1993
  13. COMPLIANCE TO POWERFUL dominant voice  Differential power quality of voices,distress, beliefs about Non-compliance Construct validity of the VCS Social rank theory applied to the experience of voices argues that compliance with a powerful dominant (voice) will vary as a function of: the power differential between the dominant (voice) and subordinate (voice hearer); the distress or fear experienced; and the beliefs about non-compliance (see Gilbert, 1992 ). We can put this critical aspect of our theory to the test. This will, in addition, serve to test the validity of the VCS if it correlates lawfully with these self-report scales. The correlation matrix at 6 months (when the VCS has more variability) is shown in Table 7 . Voice compliance was correlated significantly with both greater distress and power, with a trend for omniscience (multiple R =0.55, P &lt;0.01).
  14. Psychotic symptoms Although change in psychotic symptoms was not predicted, a significant drop occurred in PANSS positive symptoms amounting to 3.7 points in the CTCH group, from a baseline of 21.8, and a small increase occurred in the control group ( F interaction =12.6, P &lt;0.001). Similarly, there was a small but consistent reduction in negative symptoms ( F interaction =14.8, P =0.001) and general psychopathology ( F interaction = 18.8, P &lt;0.001) in the CTCH group ( Table 7 ). These effects were maintained at 12 months for positive symptoms ( F interaction = 14.2, P =0.001), negative symptoms ( F interaction =12.3, P =0.002) and general psychopathology ( F interaction =15.5, P =0.001). View this table: [in this window] [in a new window]   Table 7 Correlations between voice compliance, distress, power and omniscience of disobedience  
  15. Within the PANSS positive scale, hallucinations showed a non-significant reduction at 6 months ( F =3.8, P =0.06); however, by 12 months, no difference between the groups was observed ( F interaction =1.46, NS). In contrast, for the delusions sub-scale there was a reduction in the CTCH group at 6 months ( F interaction =5.6, P =0.0025), sustained at 12 months ( F interaction =3.98, P =0.005). Within the general psychopathology scale, there were significant changes in anxiety at 6 months ( F interaction =10.6, P =0.004) and 12 months ( F interaction =9.9, P =0.004); in tension at 6 months ( F interaction =5.1, P =0.03); and in guilty thinking at 6 months ( F interaction =4.6, P =0.042). Within the negative symptoms scale, there was a significant reduction in attention/concentration at 6 months ( F interaction =13.2, P =0.001), and disturbance of volition at 6 months ( F interaction =6.2, P =0.019) and 12 months ( F interaction =15.5, P =0.001). There was no correlation between neuroleptic dose and PANSS positive symptoms at any point