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HIV Index Testing:
The USAID DISCOVER-
Health Project Experience
Kalasa Mwanda – MD, MPH, MBA
April 11, 2019
2|
Project Objectives
USAID DISCOVER-Health:
 USAID-funded 5 year project (December, 2015 to December, 2020)
Objective 1: High Quality, Integrated Health Services are
Used More by Target Groups
 Provide an integrated package of HIV, FP/RH, and MNCH services
 Services provided predominantly through outreach
 Operating in 138 sites from 11 hubs (operational bases)
Objective 2: Provision of Integrated Health Products and
Services is Sustainable
 Provide a range of socially marketed HIV, FP/RH, and MNCH products
 Pay attention to fostering commercial sector growth
FP/RHMNCH
HIVFamily
Planning
Cervical
Cancer
Screening
General OPD
Services
HTS
ART
PMTCT
PrEP
VMMC
Condoms &
Other Prev
Antenatal &
Postnatal
Services
Child
Immunization
Under-
five
Clinic
Services delivered
primarily through
Outreach
Target hard to
reach and
underserved
communities
Goal: contribute
to HIV epidemic
control
Integrated FP/RH,
MNCH and HIV
Service Package
138 service
delivery sites
country-wide
Goal: improve
general heath
outcomes
USAID DISCOVER-Health
Package of Services Provided at Every ART Site
4|
HIV Testing
Services
1. HIV Index Testing and Partner
Notification Services
2. Voluntary Counselling and Testing
(VCT)
3. Provider-Initiated Testing and
Counselling (PITC)
4. Antenatal Clinic (ANC)
5. Voluntary Medical Male
Circumcision (VMMC)
Key Testing
Modalities
5|
HIV Index Testing: Rationale
USAID DISCOVER-Health started
HIV index testing in November, 2017
Motivated by the several clinical trials
that revealed that HIV index Testing
and PNS have positivity yield of 35 -
62%
Against the backdrop of:
• Less than 300,000 in a population of
about 1.25m PLHIV and a total
population of 15m people
• Increased donor demands for more
efficient use of HIV test kits and other
consumables
• Huge Tx_New target of 80,000
6|
8,581
14,371
11,740
9,048
1,078
2,692 2,360
0
2000
4000
6000
8000
10000
12000
14000
16000
Accepted
indexing
Contacts elicited Contacts tested Contacts tested
NEG
Contacts known
HIV+
Contacts tested
POS
Contacts
initiated
Index Testing Cascade April 2018 - February 2019
88%
tested
23% tested
HIV+
88%
initiated
Index Testing Results
7|
HIV Index Testing Presents the Highest Positivity
Yield…
4%
1%
23%
5%
0.1%
0%
5%
10%
15%
20%
25%
ANC PITC (FP) Indexing VCT VMMC
Testing Yield by Modality, April 2018 - February
2019
8|
Index Testing –
Does It Have a
Deeper Reach For
the Well Man?
ZAMPHIA 64% of men and
68% of women were tested
More males than females
contacted because index
clients are largely female
Male,
51%
Female,
49%
Proportion of People Tested Through
Indexing by Sex, April 2018 - February
2019
9|
HIV Index Testing
Yield: Is There a
Difference in
Positivity Among
Males vs.
Females?
Positivity among females is
much higher than among
males
Male…Female,
53%
Proportion of Newly Identified HIV+
Through Indexing by Sex, April 2018 -
February 2019
10|
HIV Index
Testing -
Yield and
Linkage By
Age –
What
Lessons
Can We
Draw?
Morechildren
contactedbut
positivitymuchhigher
amongadults
4,159 4,075
8,234
255
1,665
1,920
190
1,384
1,5746%
41%
23%
75%
83%
82%
0%
25%
50%
75%
100%
0
3,000
6,000
9,000
< 15 years ≥ 15 years Total
Contacts tested Contacts tested HIV+
Contacts initiated Yield
Linkage
11|
Linkage to
ART After
HIV Index
Testing
Higherlinkagerates
amongfemales
comparedtomales
88%
83%
86% 86% 87%85% 86%
91% 90% 92%
0%
25%
50%
75%
100%
≤ 14 yrs. 15-24 yrs. 25-34 yrs. 35-44 yrs. ≥ 45 yrs.
Linkage Yield Rate by Age and Sex, April
2018 - February 2019
Male Female
12|
Evidence of
Increased
Index Testing
Volumes From
Programmatic
Adjustments –
More Effective
Model Now
Implemented
2728
3151 3106
4132
672 635 759 939
0
500
1000
1500
2000
2500
3000
3500
4000
4500
Apr-Jun 2018 Jul-Sept 2018Oct-Dec 2018Jan-Mar 2019
(projected)
Index Contacts Tested and Tested HIV+
by Quarter, 2018-2019
Contacts tested Contacts tested HIV+
13|
Model Envisioned
to Up HIV Index
Testing’s
Contribution
Towards the Total
Tested
Poisedtoregistersignificant
improvementstowards40%
contributionfromindex
testing amongall testing
modalities
6985 6646 5969
3902
672 635 759
626
8.8% 8.7%
11.3%
13.8%
0.0%
5.0%
10.0%
15.0%
0
2000
4000
6000
8000
10000
Apr-Jun
2018
Jul-Sept
2018
Oct-Dec
2018
Jan-Feb
2019
Proportion of HIV+ New Clients
Identified Through Indexing by
Quarter, 2018-2019
New HIV+ from indexing
New HIV+ from all other modalities
14|
Key Programmatic Lessons Learned
1. Building adequate capacity among HCWs and counselors
in HIV Index testing is an imperative – Trained over 825 HCWs and
CHWs in HIV index testing
2. Continued mentorship and support – Team of senior/middle
program management staff to provide guidance and monitor implementation
including during deep dive data review meetings
3. The working model need not be static – Should be dynamic and
allow for changes to help attain programmatic detects - Getting the project closer
to the much desired 40% contribution for HIV index testing among all modalities
4. HIV Index Testing has potential to help extend HIV testing
services to the “well” man – This is among the very few modalities where
more males are tested compared to females

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HIV Index Testing Yields High Positivity and Reaches More Men

  • 1. HIV Index Testing: The USAID DISCOVER- Health Project Experience Kalasa Mwanda – MD, MPH, MBA April 11, 2019
  • 2. 2| Project Objectives USAID DISCOVER-Health:  USAID-funded 5 year project (December, 2015 to December, 2020) Objective 1: High Quality, Integrated Health Services are Used More by Target Groups  Provide an integrated package of HIV, FP/RH, and MNCH services  Services provided predominantly through outreach  Operating in 138 sites from 11 hubs (operational bases) Objective 2: Provision of Integrated Health Products and Services is Sustainable  Provide a range of socially marketed HIV, FP/RH, and MNCH products  Pay attention to fostering commercial sector growth
  • 3. FP/RHMNCH HIVFamily Planning Cervical Cancer Screening General OPD Services HTS ART PMTCT PrEP VMMC Condoms & Other Prev Antenatal & Postnatal Services Child Immunization Under- five Clinic Services delivered primarily through Outreach Target hard to reach and underserved communities Goal: contribute to HIV epidemic control Integrated FP/RH, MNCH and HIV Service Package 138 service delivery sites country-wide Goal: improve general heath outcomes USAID DISCOVER-Health Package of Services Provided at Every ART Site
  • 4. 4| HIV Testing Services 1. HIV Index Testing and Partner Notification Services 2. Voluntary Counselling and Testing (VCT) 3. Provider-Initiated Testing and Counselling (PITC) 4. Antenatal Clinic (ANC) 5. Voluntary Medical Male Circumcision (VMMC) Key Testing Modalities
  • 5. 5| HIV Index Testing: Rationale USAID DISCOVER-Health started HIV index testing in November, 2017 Motivated by the several clinical trials that revealed that HIV index Testing and PNS have positivity yield of 35 - 62% Against the backdrop of: • Less than 300,000 in a population of about 1.25m PLHIV and a total population of 15m people • Increased donor demands for more efficient use of HIV test kits and other consumables • Huge Tx_New target of 80,000
  • 6. 6| 8,581 14,371 11,740 9,048 1,078 2,692 2,360 0 2000 4000 6000 8000 10000 12000 14000 16000 Accepted indexing Contacts elicited Contacts tested Contacts tested NEG Contacts known HIV+ Contacts tested POS Contacts initiated Index Testing Cascade April 2018 - February 2019 88% tested 23% tested HIV+ 88% initiated Index Testing Results
  • 7. 7| HIV Index Testing Presents the Highest Positivity Yield… 4% 1% 23% 5% 0.1% 0% 5% 10% 15% 20% 25% ANC PITC (FP) Indexing VCT VMMC Testing Yield by Modality, April 2018 - February 2019
  • 8. 8| Index Testing – Does It Have a Deeper Reach For the Well Man? ZAMPHIA 64% of men and 68% of women were tested More males than females contacted because index clients are largely female Male, 51% Female, 49% Proportion of People Tested Through Indexing by Sex, April 2018 - February 2019
  • 9. 9| HIV Index Testing Yield: Is There a Difference in Positivity Among Males vs. Females? Positivity among females is much higher than among males Male…Female, 53% Proportion of Newly Identified HIV+ Through Indexing by Sex, April 2018 - February 2019
  • 10. 10| HIV Index Testing - Yield and Linkage By Age – What Lessons Can We Draw? Morechildren contactedbut positivitymuchhigher amongadults 4,159 4,075 8,234 255 1,665 1,920 190 1,384 1,5746% 41% 23% 75% 83% 82% 0% 25% 50% 75% 100% 0 3,000 6,000 9,000 < 15 years ≥ 15 years Total Contacts tested Contacts tested HIV+ Contacts initiated Yield Linkage
  • 11. 11| Linkage to ART After HIV Index Testing Higherlinkagerates amongfemales comparedtomales 88% 83% 86% 86% 87%85% 86% 91% 90% 92% 0% 25% 50% 75% 100% ≤ 14 yrs. 15-24 yrs. 25-34 yrs. 35-44 yrs. ≥ 45 yrs. Linkage Yield Rate by Age and Sex, April 2018 - February 2019 Male Female
  • 12. 12| Evidence of Increased Index Testing Volumes From Programmatic Adjustments – More Effective Model Now Implemented 2728 3151 3106 4132 672 635 759 939 0 500 1000 1500 2000 2500 3000 3500 4000 4500 Apr-Jun 2018 Jul-Sept 2018Oct-Dec 2018Jan-Mar 2019 (projected) Index Contacts Tested and Tested HIV+ by Quarter, 2018-2019 Contacts tested Contacts tested HIV+
  • 13. 13| Model Envisioned to Up HIV Index Testing’s Contribution Towards the Total Tested Poisedtoregistersignificant improvementstowards40% contributionfromindex testing amongall testing modalities 6985 6646 5969 3902 672 635 759 626 8.8% 8.7% 11.3% 13.8% 0.0% 5.0% 10.0% 15.0% 0 2000 4000 6000 8000 10000 Apr-Jun 2018 Jul-Sept 2018 Oct-Dec 2018 Jan-Feb 2019 Proportion of HIV+ New Clients Identified Through Indexing by Quarter, 2018-2019 New HIV+ from indexing New HIV+ from all other modalities
  • 14. 14| Key Programmatic Lessons Learned 1. Building adequate capacity among HCWs and counselors in HIV Index testing is an imperative – Trained over 825 HCWs and CHWs in HIV index testing 2. Continued mentorship and support – Team of senior/middle program management staff to provide guidance and monitor implementation including during deep dive data review meetings 3. The working model need not be static – Should be dynamic and allow for changes to help attain programmatic detects - Getting the project closer to the much desired 40% contribution for HIV index testing among all modalities 4. HIV Index Testing has potential to help extend HIV testing services to the “well” man – This is among the very few modalities where more males are tested compared to females

Editor's Notes

  1.  Speak to failures the project has experienced over the past year and how you responded