. chronic inflammation granulomatous inflammation

2. APC
CD4 T lymphocytes
Monocytes
Epitheloid Macrophages

3. Tuberculosis Pathogenesis
• Bacterial entry
• T Lymphocytes.
• Macrophages.
• Epitheloid cells.
• Proliferation.
• Central Necrosis.
• Giant cell formation.
• Fibrosis.
Mechanisms of
granuloma
formation

4. Infection - Immunity
Pathogenesis of TB:

5. • MBBS ST CCLL:
 Mycobacterium Tuberculosis
 Brucellosis
 Berryliosis
 Syphilis
 Sarcoidosis
 Cat-scratch disease
 Crohn's disease
 Leprosy
 Lipid granuloma- Foreign body granulomas
 Lymphogranuloma Inguinale

6. TB- Lymph node

7. Intestinal Tuberculosis

8. Lung Miliary Tuberculosis

10. Tubercular Caseous Necrosis & Giant cells

11. Tubercular Granulomatous Inflammation

12. Epitheloid Macrophages

14. Foreign body granuloma.
Lipid granulomas.
Sarcoidosis.
Crohns disease.
Fungal infections.
Cat scratch disease.
Brucellosis.
Leprosy.
Syphilis.
Berilliosis
Lymphogranuloma venerium