Cystic disease of the kidney

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Disease Kidney Size Cyst Size Cyst Location Liver Nephronophthisis Small 1MM-2CM Medullary Normal Acquired Cysts Normal/Small 0.5-3CM Any Normal Medullary Sponge Normal/Enlarged MM Precalyceal Normal ARPKD Enlarged MM Any Fibrosis Multicystic Dysplastic Enlarged 1MM-10CM Any Normal ADPKD Enlarged MM-10CM Any Cysts

Diagnosis/Screening ,[object Object],[object Object],[object Object]

Family History Positive - Genotype Unknown ,[object Object],[object Object],[object Object]

Family History of PKD1 ,[object Object],[object Object],[object Object],[object Object]

Family History of PKD2 ,[object Object],[object Object]

Criteria for Exclusion of Disease (if family history positive) ,[object Object],[object Object],[object Object]

Alternate Imaging ,[object Object],[object Object],[object Object]

Absence of Family History ,[object Object],[object Object],[object Object]

Genetic Testing ,[object Object],[object Object]

Direct DNA Analysis ,[object Object],[object Object],[object Object],[object Object]

Clinical Course ,[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object]

ARPKD ,[object Object],[object Object],[object Object]

Features ,[object Object],[object Object],[object Object]

Nephronophthisis ,[object Object],[object Object],[object Object]

Manifestations ,[object Object],[object Object],[object Object]

Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Medullary Cystic Kidney Disease ,[object Object],[object Object]

MCKD2 ,[object Object],[object Object]

MCKD1 ,[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object]

Von-Hippel Lindau ,[object Object],[object Object],[object Object]

Classifications of glomerulocystic kidney disease Example Familial nonsyndromic Autosomal dominant polycystic kidney disease in young infants Associated with inheritable malformation syndromes Tuberous sclerosis complex Syndromic, non-Mendelian Trisomy 9, 13, or 18 Sporadic New mutations Acquired and dysplastic kidneys Hemolytic uremic syndrome and obstructive uropathy

Cystic disease of the kidney

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Cystic disease of the kidney