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Night Blindness 
(Nyctalopia) 
By Kevin J Ambadan
Definition 
Derived from Greek words: nykt = ‘night’ 
& alaos = ‘blindness’ 
It is a condition in which it difficult or 
impossible to see in relatively low light. 
Symptom of several eye diseases.
Etiology 
Night Blindness may exist from birth or be caused by 
injury or malnutrition (for example, vitamin A 
deificiency). 
Causes: 
• Vitamin A deficiency 
• Retinitis Pigmentosa & other tapetoretinal 
degenerations 
• Congenital night blindness 
• Pathological myopia 
• Peripheral cortical cataract & Corneal 
opacities 
• Advanced Primary open angle glaucoma
Vitamin A Deficiency 
Inhibits the production of rhodopsin (the eye 
pigment responsible for sensing low light 
situations) found in the retina, composed of 
retinal (active form of Vitamin A) 
The decreased amount of rhodopsin in the 
eye implies that there is inadequate retinal to 
bind to opsin. Therefore, night blindness 
results.
Retinitis Pigmentosa 
A disorder in which the rod cells in the retina 
gradually lose their to respond to the light. 
Patients suffering from this genetic condition 
have progressive nyctalopia and eventually 
their daytime vision may also be affected 
(Hamarlopia).
Congenital Stationary 
Night Blindness 
It is a rare X-linked non-progressive retinal 
disorder. 
Caused by malfunction in neurotransmission 
from rods to bipolar cells in the retina. 
Also known as Oguchi’s disease.
Peripheral Cortical 
Cataract 
The outer area of the retina is made up of 
more rods than cones. 
As rods are responsible for vision in dim light, 
loss of peripheral vision often results in night 
blindness.
Treatment 
TREAT THE UNDERLYING CAUSE!!!! 
The treatment method depends on the cause 
of the night blindness: 
• Vitamin A deficiency - treated by giving 
Vitamin A supplement 
• Retinitis Pigmentosa – not completely 
curable, but the rate of progression of this 
disease can be reduced by intake of vitamin 
A supplements and surgeries (retinal 
transplant)
Treatment 
• Myopia – use of corrective glasses or 
lenses or refractive surgery 
• Glaucoma – switching of glaucoma 
medicines may help 
• Peripheral Cataract – Cataract surgeries 
• Oguchi’s Disease – incurable
The end

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Night Blindness

  • 1. Night Blindness (Nyctalopia) By Kevin J Ambadan
  • 2. Definition Derived from Greek words: nykt = ‘night’ & alaos = ‘blindness’ It is a condition in which it difficult or impossible to see in relatively low light. Symptom of several eye diseases.
  • 3. Etiology Night Blindness may exist from birth or be caused by injury or malnutrition (for example, vitamin A deificiency). Causes: • Vitamin A deficiency • Retinitis Pigmentosa & other tapetoretinal degenerations • Congenital night blindness • Pathological myopia • Peripheral cortical cataract & Corneal opacities • Advanced Primary open angle glaucoma
  • 4. Vitamin A Deficiency Inhibits the production of rhodopsin (the eye pigment responsible for sensing low light situations) found in the retina, composed of retinal (active form of Vitamin A) The decreased amount of rhodopsin in the eye implies that there is inadequate retinal to bind to opsin. Therefore, night blindness results.
  • 5. Retinitis Pigmentosa A disorder in which the rod cells in the retina gradually lose their to respond to the light. Patients suffering from this genetic condition have progressive nyctalopia and eventually their daytime vision may also be affected (Hamarlopia).
  • 6. Congenital Stationary Night Blindness It is a rare X-linked non-progressive retinal disorder. Caused by malfunction in neurotransmission from rods to bipolar cells in the retina. Also known as Oguchi’s disease.
  • 7. Peripheral Cortical Cataract The outer area of the retina is made up of more rods than cones. As rods are responsible for vision in dim light, loss of peripheral vision often results in night blindness.
  • 8. Treatment TREAT THE UNDERLYING CAUSE!!!! The treatment method depends on the cause of the night blindness: • Vitamin A deficiency - treated by giving Vitamin A supplement • Retinitis Pigmentosa – not completely curable, but the rate of progression of this disease can be reduced by intake of vitamin A supplements and surgeries (retinal transplant)
  • 9. Treatment • Myopia – use of corrective glasses or lenses or refractive surgery • Glaucoma – switching of glaucoma medicines may help • Peripheral Cataract – Cataract surgeries • Oguchi’s Disease – incurable