This ppt contain information about the old traditional drug cur cumin , its new nano scale formulations and how its is being used in Alzheimer patient

1. By:
Kushali
Jain.D
M.pharma

4.  Turmeric (Curcuma longa) is
an amazing ingredient with a
rich traditional history as a
dietary spice and herbal
supplement in ancient china and
India.
 This characteristic yellow
colored spice, derived from the
rhizome of the plant (C. longa),
is a member of Zingiberaceae
family and is widely cultivated in
India and Southeast Asia.

7. Cleavage
STRESS,
INJURY
Protective mechanism
α- secretase β- secretase
40 amino acid Cleavage (42-amino acidgroups)

8. A-β fibril plaques
(intracellular)
Curcumin
Evert insidious evolution
It helps macrophages to clear
amyloid-β plaques found in AD
Curcumin has shown
1. Anti inflammatory property
2. Anti-oxidant property
Oxidative
damage
Inflamm
ation
β –Amyloid plaques in Brain
Intracellular
aggregates
Dementia

11. Free Curcumin
Poorly dispersible in
water
Reduced
Bioavailability
Nanocurcumin
 Dispersible in water
 Sustained drug release
kinetics
 Improved Bioavailability
 Improved cellular uptake

12. Nanorobotics is emerging field of a nanotechnology
Nanorobot skeleton
Made up
Carbon and its tool kit
Contain
Medicine cavity
Consist of
Medicine, Micro camera, payload, Capacitor
As nano robot have special sensor which detect
target molecule in Human body
Used in treatment of
Various disease which include Cancer ,Diabetes,
Alzheimer's etc.