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PARASITOLOGY
MICROBIOLOGY LECTURE
DEFINITION OF TERMS
• Parasitology
-Science that deals with organisms that takes
up their abode temporarily or permanently for
the purpose of procuring food and the
relationship of this organism to the host.
• Parasite
-Living organism which for the purpose of
procuring food and shelter take up their
abode temporarily or permanently on another
living organism.
-An organism that relies on another species.
DEFINITION OF TERMS
• Parasitism
-Any reciprocal association in which a species
depends upon another for its existence
-The HOST is always harmed.
• Commensalism
-A kind of association between two living
organisms of different species in which one of
the member is benefitted but the other
member is neither harmed nor destroyed.
DEFINITION OF TERMS
• Mutualism
-Association between two living organisms
of different species in which both members
are dependent upon each other that life
apart is impossible.
• Predation
-A bigger animal attacks a smaller or weaker
animal.
DEFINITION OF TERMS
• Predator
-The bigger animal
• Prey
-The smaller or weaker animal
Parasites describe a
number of multi-cellular organisms that
are able to survive on or within the
human body, but have side effects that
are harmful to human health.
Technically speaking, a

parasite has two

characteristics:
• Part of its life cycle must be spent within a
host body; and
• It requires sustenance from the host in order
to survive during this period.
However, the term 'parasite' is usually used to
refer to any organism that meets either of
these characteristics.
One intriguing aspect of human parasites is
the number of strategies they have
evolved to enter the host. Infections can
be transmitted by the fecal–oral route
(e.g., amebiasis, ascariasis), by the direct
penetration of unbroken skin infection
(e.g., hookworm, schistosomiasis), or by
the bites of arthropod vectors
(e.g., malaria, filariasis).
With the first two routes of
transmission, acquisition usually results
from ingestion of contaminated food or
water or from inadequate control of human
wastes in soil or water. Although many of
the parasites using those routes of
transmission live in the gastrointestinal
tract, several invade and infect the internal
organs or skin, and a few cause disease in
both the intestine and deeper tissues.
Most arthropodborne infections are
transmitted to humans through bite
wounds. Transmission through arthropods
can be extraordinarily efficient. In
fact, malaria can be acquired from the bite
of a single infected mosquito during a stop
at an airport in an endemic area. In
addition, some arthropodborne infections
can be transmitted by the transfusion of
blood from asymptomatic infected
Parasitic Structure
Parasitic Structure
Spread and Multiplication
Inoculum Size
• The effective inoculum size has been
determined for a few parasites by
experimental infections in human
volunteers and animals, usually in
conjunction with quantitative
epidemiologic studies.
Spread and Multiplication
Parasite Survival Mechanisms in
Immunologically Normal Hosts
• Like other microorganisms, parasites
elicit both antibody- and cell-mediated
responses. However, they are adept
at circumventing those host defenses.
Spread and Mulitiplication
Species and Tissue Tropisms
• The life cycles of parasites are determined by
species and tissue tropisms, which define the
hosts that parasites can infect and the organs
and tissues in which they can survive.
• Temperature also plays an important role in the
ability of parasites to infect humans and cause
disease.
• Temperature changes also induce stage-specific
transitions in many parasites.
Environmental Constraints on
Transmission
Examination of the parasitic life cycle
often explains why a given parasitic
disease is found in one area of the
world and not another. For
example, the transmission of
schistosomiasis depends on an
intermediate snail host that is not
present in North America or Europe.
Environmental Constraints on
Transmission
Thus, viable eggs in the stool or urine of infected
persons cannot produce the forms infective for
humans (cercariae) because there are no
intermediate snail hosts in which the parasite
can mature. For that reason, human
schistosomiasis is not endemic in the United
States and will not be, unless an intermediate
snail host becomes established.
Parasitic nutrition
Parasitic nutrition is a mode
of heterotrophic nutrition where an
organism (known as a parasite) lives on
the body surface or inside the body of
another type of organism (known as
a host). The parasite obtains nutrition
directly from the body of the host. Since
these parasites derive their nourishment
from their host, this symbiotic interaction is
often described as harmful to the host.
Parasitic nutrition
Parasites are dependent on their host
for survival, since the host provides
nutrition and protection. As a result of
this dependence, parasites have
considerable modifications to
optimise parasitic nutrition and
therefore their survival.
Parasitic nutrition
Parasites are divided into two
groups: endoparasites and ectoparasi
tes. Endoparasites are parasites that
live inside the body of the
host, whereas ectoparasites are
parasites that live on the outer
surface of the host and generally
attach themselves during feeding.
Parasitic nutrition
Parasites require nutrients to carry
out essential functions including
reproduction and growth.
Essentially, the nutrients required
from the host
are carbohydrates, amino
acids and lipids.
Parasitic nutrition
Carbohydrates are utilised to generate
energy, whilst amino acids and fatty acids
are involved in the synthesis of
macromolecules and the production of
eggs. Most parasites are heterotrophs, so
they therefore are unable to synthesise
their own 'food' i.e. organic compounds
and must acquire these from their host.
Parasitic nutrition
Endoparasites Endoparasitism
are parasites which live inside the body
of the host. This group
includes helminths, trematodes and c
estodes. Endoparasites are two
groups of parasites: intercellular
andintracellular parasites
Parasitic nutrition
Intercellular parasites live in
spaces within the host e.g. the
alimentary canal, whereas
intracellular parasites live in cells
within the host e.g. erythrocytes.
Intracellular parasites typically rely on
a third organism, a vector, to transmit
the parasite between hosts.
Parasitic nutrition
• Ectoparasitism
Ectoparasites live on the outer surface of the
host. Ectoparasites do not have a readily
available source of nutrients available on the
outer surface of the host so they therefore
require adaptations which enable them to gain
access to host nutrients. This requires
penetrative features which can insert into the
host, as well as the ability to secrete digestive
enzymes and the presence of a gut to digest
host-derived nutrients
Prevention and Treatment
A combination of pumpkin
seed, garlic, cramp bark, capsicum and
thyme, can chase away tapeworms. An
herbal mixture of black walnut
leaves, wormwood, quassia, cloves and
male fern, helps eliminate
roundworms. Three parts capsicum, two
parts wormwood and one part sage is an
effective combination against
worms. Black walnut, sassafras and pine
Prevention and Treatment
Preventing Re-infection:
• Periodically consume curry meals (highly antiparasitic) followed by probiotics treatment (to reestablish healthy intestinal flora).
• It is a realistic approach to EXPECT to become
infected by destructive parasites and to undergo
a periodic (i.e. annual) parasitic cleanse, as
most fresh waters globally located near human
habitation ARE polluted.
Prevention and Treatment
Preventing Re-infection:
• Be sure that all meat, chicken and fish is cooked
thoroughly.
• Don't use a microwave to cook meat, chicken or
fish. Microwaves often don't heat foods
completely.
• Wash all fruits and vegetables in clean water
before eating (to prevent roundworm and
whipworm infection)
Prevention and Treatment
Preventing Re-infection:
• Always wash your hands, kitchen counters and
utensils with hot soapy water after cutting or
handling raw meat, chicken or fish.
• Be sure that all meat, chicken and fish is cooked
thoroughly.
• Don't use a microwave to cook meat, chicken or
fish. Microwaves often don't heat foods
completely.
Prevention and Treatment
Preventing Re-infection:
• Always wear shoes or slippers (to
prevent hookworm infection)
• Do not use water from septic tanks or other
potentially contaminated sources for watering
vegetables
• Contain all fecal matter (e.g. by using a toilet or
latrine, rather than "as nature intended" outside)
• Teach children proper hygiene i.e. washing
hands after going to the toilet, playing outside
and before preparing or eating
Prevention and Treatment
Preventing Re-infection:
• If you have parasites, you can reduce the
likelihood of passing them on to others by
carefully washing your hands after having bowel
movements and cleaning the genital area before
having sex.
• Wear gloves when changing the cat
box. Deworm pets periodically.
• Avoid swallowing river, stream or lake water
when swimming in them. Better yet, avoid
swimming in them altogether.
Prevention and Treatment
Preventing Re-infection:
• Eat high-fiber foods and avoid sugar and
other refined carbohydrates.
• Keep your body slightly acidic by including
pumpkin seeds, calmyrna
figs, garlic, apple cider vinegar, cranberry
juice and pomegranates in your diet.
• Avoid eating water chestnuts and
watercress.

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Parasitology

  • 2. DEFINITION OF TERMS • Parasitology -Science that deals with organisms that takes up their abode temporarily or permanently for the purpose of procuring food and the relationship of this organism to the host. • Parasite -Living organism which for the purpose of procuring food and shelter take up their abode temporarily or permanently on another living organism. -An organism that relies on another species.
  • 3. DEFINITION OF TERMS • Parasitism -Any reciprocal association in which a species depends upon another for its existence -The HOST is always harmed. • Commensalism -A kind of association between two living organisms of different species in which one of the member is benefitted but the other member is neither harmed nor destroyed.
  • 4. DEFINITION OF TERMS • Mutualism -Association between two living organisms of different species in which both members are dependent upon each other that life apart is impossible. • Predation -A bigger animal attacks a smaller or weaker animal.
  • 5. DEFINITION OF TERMS • Predator -The bigger animal • Prey -The smaller or weaker animal
  • 6. Parasites describe a number of multi-cellular organisms that are able to survive on or within the human body, but have side effects that are harmful to human health.
  • 7. Technically speaking, a parasite has two characteristics: • Part of its life cycle must be spent within a host body; and • It requires sustenance from the host in order to survive during this period. However, the term 'parasite' is usually used to refer to any organism that meets either of these characteristics.
  • 8. One intriguing aspect of human parasites is the number of strategies they have evolved to enter the host. Infections can be transmitted by the fecal–oral route (e.g., amebiasis, ascariasis), by the direct penetration of unbroken skin infection (e.g., hookworm, schistosomiasis), or by the bites of arthropod vectors (e.g., malaria, filariasis).
  • 9. With the first two routes of transmission, acquisition usually results from ingestion of contaminated food or water or from inadequate control of human wastes in soil or water. Although many of the parasites using those routes of transmission live in the gastrointestinal tract, several invade and infect the internal organs or skin, and a few cause disease in both the intestine and deeper tissues.
  • 10. Most arthropodborne infections are transmitted to humans through bite wounds. Transmission through arthropods can be extraordinarily efficient. In fact, malaria can be acquired from the bite of a single infected mosquito during a stop at an airport in an endemic area. In addition, some arthropodborne infections can be transmitted by the transfusion of blood from asymptomatic infected
  • 13. Spread and Multiplication Inoculum Size • The effective inoculum size has been determined for a few parasites by experimental infections in human volunteers and animals, usually in conjunction with quantitative epidemiologic studies.
  • 14. Spread and Multiplication Parasite Survival Mechanisms in Immunologically Normal Hosts • Like other microorganisms, parasites elicit both antibody- and cell-mediated responses. However, they are adept at circumventing those host defenses.
  • 15. Spread and Mulitiplication Species and Tissue Tropisms • The life cycles of parasites are determined by species and tissue tropisms, which define the hosts that parasites can infect and the organs and tissues in which they can survive. • Temperature also plays an important role in the ability of parasites to infect humans and cause disease. • Temperature changes also induce stage-specific transitions in many parasites.
  • 16. Environmental Constraints on Transmission Examination of the parasitic life cycle often explains why a given parasitic disease is found in one area of the world and not another. For example, the transmission of schistosomiasis depends on an intermediate snail host that is not present in North America or Europe.
  • 17. Environmental Constraints on Transmission Thus, viable eggs in the stool or urine of infected persons cannot produce the forms infective for humans (cercariae) because there are no intermediate snail hosts in which the parasite can mature. For that reason, human schistosomiasis is not endemic in the United States and will not be, unless an intermediate snail host becomes established.
  • 18. Parasitic nutrition Parasitic nutrition is a mode of heterotrophic nutrition where an organism (known as a parasite) lives on the body surface or inside the body of another type of organism (known as a host). The parasite obtains nutrition directly from the body of the host. Since these parasites derive their nourishment from their host, this symbiotic interaction is often described as harmful to the host.
  • 19. Parasitic nutrition Parasites are dependent on their host for survival, since the host provides nutrition and protection. As a result of this dependence, parasites have considerable modifications to optimise parasitic nutrition and therefore their survival.
  • 20. Parasitic nutrition Parasites are divided into two groups: endoparasites and ectoparasi tes. Endoparasites are parasites that live inside the body of the host, whereas ectoparasites are parasites that live on the outer surface of the host and generally attach themselves during feeding.
  • 21. Parasitic nutrition Parasites require nutrients to carry out essential functions including reproduction and growth. Essentially, the nutrients required from the host are carbohydrates, amino acids and lipids.
  • 22. Parasitic nutrition Carbohydrates are utilised to generate energy, whilst amino acids and fatty acids are involved in the synthesis of macromolecules and the production of eggs. Most parasites are heterotrophs, so they therefore are unable to synthesise their own 'food' i.e. organic compounds and must acquire these from their host.
  • 23. Parasitic nutrition Endoparasites Endoparasitism are parasites which live inside the body of the host. This group includes helminths, trematodes and c estodes. Endoparasites are two groups of parasites: intercellular andintracellular parasites
  • 24. Parasitic nutrition Intercellular parasites live in spaces within the host e.g. the alimentary canal, whereas intracellular parasites live in cells within the host e.g. erythrocytes. Intracellular parasites typically rely on a third organism, a vector, to transmit the parasite between hosts.
  • 25. Parasitic nutrition • Ectoparasitism Ectoparasites live on the outer surface of the host. Ectoparasites do not have a readily available source of nutrients available on the outer surface of the host so they therefore require adaptations which enable them to gain access to host nutrients. This requires penetrative features which can insert into the host, as well as the ability to secrete digestive enzymes and the presence of a gut to digest host-derived nutrients
  • 26. Prevention and Treatment A combination of pumpkin seed, garlic, cramp bark, capsicum and thyme, can chase away tapeworms. An herbal mixture of black walnut leaves, wormwood, quassia, cloves and male fern, helps eliminate roundworms. Three parts capsicum, two parts wormwood and one part sage is an effective combination against worms. Black walnut, sassafras and pine
  • 27. Prevention and Treatment Preventing Re-infection: • Periodically consume curry meals (highly antiparasitic) followed by probiotics treatment (to reestablish healthy intestinal flora). • It is a realistic approach to EXPECT to become infected by destructive parasites and to undergo a periodic (i.e. annual) parasitic cleanse, as most fresh waters globally located near human habitation ARE polluted.
  • 28. Prevention and Treatment Preventing Re-infection: • Be sure that all meat, chicken and fish is cooked thoroughly. • Don't use a microwave to cook meat, chicken or fish. Microwaves often don't heat foods completely. • Wash all fruits and vegetables in clean water before eating (to prevent roundworm and whipworm infection)
  • 29. Prevention and Treatment Preventing Re-infection: • Always wash your hands, kitchen counters and utensils with hot soapy water after cutting or handling raw meat, chicken or fish. • Be sure that all meat, chicken and fish is cooked thoroughly. • Don't use a microwave to cook meat, chicken or fish. Microwaves often don't heat foods completely.
  • 30. Prevention and Treatment Preventing Re-infection: • Always wear shoes or slippers (to prevent hookworm infection) • Do not use water from septic tanks or other potentially contaminated sources for watering vegetables • Contain all fecal matter (e.g. by using a toilet or latrine, rather than "as nature intended" outside) • Teach children proper hygiene i.e. washing hands after going to the toilet, playing outside and before preparing or eating
  • 31. Prevention and Treatment Preventing Re-infection: • If you have parasites, you can reduce the likelihood of passing them on to others by carefully washing your hands after having bowel movements and cleaning the genital area before having sex. • Wear gloves when changing the cat box. Deworm pets periodically. • Avoid swallowing river, stream or lake water when swimming in them. Better yet, avoid swimming in them altogether.
  • 32. Prevention and Treatment Preventing Re-infection: • Eat high-fiber foods and avoid sugar and other refined carbohydrates. • Keep your body slightly acidic by including pumpkin seeds, calmyrna figs, garlic, apple cider vinegar, cranberry juice and pomegranates in your diet. • Avoid eating water chestnuts and watercress.