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Encouraging innovative
approaches and policies to
improve primary care for older
people
Steve Iliffe, Professor of Primary Care for Older People at
University College London
Kilburn Locality-based Commissioning Board, Brent CCG

Kings Fund
Topics
•
•
•
•
•
•

Factoids: integration
Policy zombies: anticipatory care
Evidence for innovative primary care
What is to be done?
Who can do it?
An example

2
Beware of factoids
Integration of services will help meet the needs of an
ageing society
Necessary ingredients
• Close-knit professional networks
• Mutual sense of long-term obligation
• Little concern about reciprocation
• High degree of mutual trust
• Joint arrangements as core business
Glendenning C Breaking down barriers: integrating health & social care services for older
people in England Health Policy 2002;65:139-151
3
Integration of services: Leutz’s rules
1. You can integrate all of the services for some of
the people, some of the services for all of the
people, but you can’t integrate all of the services
for all of the people
2. Integration costs before it pays
3. Your integration is my fragmentation
4. You cannot integrate a square peg and a round
hole
5. The one who integrates calls the tune
Leutz W Five laws for integrating medical and social services: lessons from the United
States and the United Kingdom Millbank Quarterly 1999; 77:77-110
4
Beware of Policy zombies
Intellectually dead ideas still moving around
Anticipatory care for older people in
general practice will reduce demand
for hospital services.

5
Is anticipatory care for older people in
the community clinically- and costeffective?

Not yet
Promoting health & well-being in later life: interventions in primary care
and community settings Chief Scientist Office, Scottish Government
www.SCPHRP.ac.uk

6
Anticipatory care: experience up to 1990
Health promotion trials for older people in US, UK & Denmark
up to 1990 showed:
•
•
•
•
•
•
•

A rise in morale.
Increased referrals to all agencies.
Reduced duration of in-patient stay (sometimes).
Increased in-patient rates (mostly respite care).
Reduction in mortality in some trials.
No improvement in functional ability.
GP workload increased unless alternative services were
organised
Stuck AE, et al (1993) Effects of a comprehensive geriatric assessment on survival, residence
and function; a meta-analysis of controlled trials Lancet;342:1032-6
7
Negative & ambiguous experiences

• MRC UK trial: little or no benefits to quality of life or health
outcomes
Fletcher AE, et al (2004) Population-based multidimensional assessment of older people in UK
general practice: a cluster-randomised factorial trial. Lancet 2004; 364: 1667-77

• Systematic review of 15 trials of preventive home visits: no
clear evidence in favour of effectiveness.
Jolanda C M van Haastregt et al Effects of preventive home visits to elderly people living in the
community: systematic review
BMJ 2000;320:754-758

•

ProAge study: no change in health risk behaviours
Harari D et al Promotion of health in older people: a randomised controlled trial of health risk
appraisal in British general practice Age & Ageing 2008; 37: 565-571

8
Case management
Expectations that case management would reduce
hospital admission rates for frail older people have
not been achieved
Gravelle et al. Impact of case management (Evercare) on frail elderly patients: controlled
before and after analysis of quantitative outcome data. BMJ 2007; 334:31.

Disruption of established nursing teams and
services, and of ‘communities of practice’
Iliffe et al Nurse case management and General Practice: implications for
practice-based commissioning BJGP 2011; 61(591): 658-665.

9
Persistent optimism
• CGA plus case management are beginning to show an
impact on function
Stuck AE, Beck JC, Egger M Preventing disability in elderly people. Lancet 2004; 364: 1641-2

• Educational professionals doing preventive home visits
improve older people’s functional mobility
Hendrickensen C, Vass M Preventive home visits to elderly people in Denmark Zeitschrift für
Gerontologie und Geriatrie 2005; 38:i31-i33

• Nurse-led case management impacts positively on
functional ability, caregiver burden and satisfaction
JM Morales-Asencio, et al Effectiveness of a nurse-led case management home care model in
Primary Health Care. A quasi-experimental, controlled, multi-centre study BMC Health Services
Research 2008, 8:193doi:10.1186/1472-6963-8-193

10
How big is the intervention effect? (Size
matters)
This matters to…
• Commissioners considering investment
• Primary care professionals considering skill
improvement
• Hospitals managing demand
• Individuals thinking of their own time & effort

11
Definitions
• Relative risk (RR): risk of developing a disease or
disability relative to exposure to a preventive
measure. Relative risk of 1 means no protective
effect has occurred. RR of < 1 means there is a
protective effect.
• Standardised Mean Difference (SMD): Used for
continuous outcomes (such as symptom scores).
Mean differences in outcomes between groups
are standardised to allow for different scoring
methods. Negative SMDs are desirable.
12
Relative risk of outcomes by interventions
Beswick AD et al Complex interventions to improve physical function and maintain independent living in elderly people
Lancet 2008;371:725-735

Study context

Loss of physical
function
(SMD)

People falling
(RR)

CGA older people

-0.12 (-0.67 to 0.08)

0.76 (0.670.86)

0.98 (0.92-1.03)

CGA frail older
people

-0.1 (-0.6 to 0.04)

0.99 (0.89 –
1.1)

0.90 (0.84-0.98)

Falls prevention

-0.25 (-0.36 to 0.13)

0.92 (0.870.97)

0.84 (0.61-1.16)

All complex
interventions

-0.08 (-0.11 to
0.06)

0.90 (0.960.95)

0.94 (0.91-0.97)

Hospital
admission
(RR)

13
In summary

• Some evidence that some targeted interventions
in some health care systems may be effective in
improving function.
• Unclear what the effective ingredients of
intervention are.
• No real sense of cost-benefit of interventions.

14
What is to be done? (in the conditions in which we
find ourselves, not in the ones we would like)
MRC approach to complex interventions
• Conceptual modelling (can we see what to do?)
• Proof of concept, case study (can we put it together?)
• Pilot studies (can others do it?)
• Rehearsal ‘trial’ (can it fit into an experiment?)
• Full scale comparative study (does it work, is it harmful?)
• Economic evaluation (is it worth it?)

15
Who should do the developmental work?
Will commissioners promote innovation?
• High risk: naïve, credulous or conflicted commissioners

Will commissioners and innovators work within an
informed research and development culture?
• Medium risk: commissioners make little use of CLAHRCs

Will NHS funding streams support studies of
innovation?
• Low risk; central co-ordination of R&D funding
16
WISH study (Well-being Interventions for Social &
Health needs)
• GP based tailored intervention aimed at 65+ age group
• Multidimensional intervention ~ automated CGA with
follow-up in practices
• Four practices, urban & rural
• GP Commissioners & local councils (Ealing &
Hertfordshire)
• Three University Departments : UCL (primary care,
economics, environment) Herts (health services research,
nursing) & Kings (social care, public involvement)
• MRC funding for pilot study (2012-2014)
17
Thank you for listening!

s.iliffe@ucl.ac.uk

18

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Steve Iliffe: Encouraging innovative approaches and policies to improve primary care for older people

  • 1. Encouraging innovative approaches and policies to improve primary care for older people Steve Iliffe, Professor of Primary Care for Older People at University College London Kilburn Locality-based Commissioning Board, Brent CCG Kings Fund
  • 2. Topics • • • • • • Factoids: integration Policy zombies: anticipatory care Evidence for innovative primary care What is to be done? Who can do it? An example 2
  • 3. Beware of factoids Integration of services will help meet the needs of an ageing society Necessary ingredients • Close-knit professional networks • Mutual sense of long-term obligation • Little concern about reciprocation • High degree of mutual trust • Joint arrangements as core business Glendenning C Breaking down barriers: integrating health & social care services for older people in England Health Policy 2002;65:139-151 3
  • 4. Integration of services: Leutz’s rules 1. You can integrate all of the services for some of the people, some of the services for all of the people, but you can’t integrate all of the services for all of the people 2. Integration costs before it pays 3. Your integration is my fragmentation 4. You cannot integrate a square peg and a round hole 5. The one who integrates calls the tune Leutz W Five laws for integrating medical and social services: lessons from the United States and the United Kingdom Millbank Quarterly 1999; 77:77-110 4
  • 5. Beware of Policy zombies Intellectually dead ideas still moving around Anticipatory care for older people in general practice will reduce demand for hospital services. 5
  • 6. Is anticipatory care for older people in the community clinically- and costeffective? Not yet Promoting health & well-being in later life: interventions in primary care and community settings Chief Scientist Office, Scottish Government www.SCPHRP.ac.uk 6
  • 7. Anticipatory care: experience up to 1990 Health promotion trials for older people in US, UK & Denmark up to 1990 showed: • • • • • • • A rise in morale. Increased referrals to all agencies. Reduced duration of in-patient stay (sometimes). Increased in-patient rates (mostly respite care). Reduction in mortality in some trials. No improvement in functional ability. GP workload increased unless alternative services were organised Stuck AE, et al (1993) Effects of a comprehensive geriatric assessment on survival, residence and function; a meta-analysis of controlled trials Lancet;342:1032-6 7
  • 8. Negative & ambiguous experiences • MRC UK trial: little or no benefits to quality of life or health outcomes Fletcher AE, et al (2004) Population-based multidimensional assessment of older people in UK general practice: a cluster-randomised factorial trial. Lancet 2004; 364: 1667-77 • Systematic review of 15 trials of preventive home visits: no clear evidence in favour of effectiveness. Jolanda C M van Haastregt et al Effects of preventive home visits to elderly people living in the community: systematic review BMJ 2000;320:754-758 • ProAge study: no change in health risk behaviours Harari D et al Promotion of health in older people: a randomised controlled trial of health risk appraisal in British general practice Age & Ageing 2008; 37: 565-571 8
  • 9. Case management Expectations that case management would reduce hospital admission rates for frail older people have not been achieved Gravelle et al. Impact of case management (Evercare) on frail elderly patients: controlled before and after analysis of quantitative outcome data. BMJ 2007; 334:31. Disruption of established nursing teams and services, and of ‘communities of practice’ Iliffe et al Nurse case management and General Practice: implications for practice-based commissioning BJGP 2011; 61(591): 658-665. 9
  • 10. Persistent optimism • CGA plus case management are beginning to show an impact on function Stuck AE, Beck JC, Egger M Preventing disability in elderly people. Lancet 2004; 364: 1641-2 • Educational professionals doing preventive home visits improve older people’s functional mobility Hendrickensen C, Vass M Preventive home visits to elderly people in Denmark Zeitschrift für Gerontologie und Geriatrie 2005; 38:i31-i33 • Nurse-led case management impacts positively on functional ability, caregiver burden and satisfaction JM Morales-Asencio, et al Effectiveness of a nurse-led case management home care model in Primary Health Care. A quasi-experimental, controlled, multi-centre study BMC Health Services Research 2008, 8:193doi:10.1186/1472-6963-8-193 10
  • 11. How big is the intervention effect? (Size matters) This matters to… • Commissioners considering investment • Primary care professionals considering skill improvement • Hospitals managing demand • Individuals thinking of their own time & effort 11
  • 12. Definitions • Relative risk (RR): risk of developing a disease or disability relative to exposure to a preventive measure. Relative risk of 1 means no protective effect has occurred. RR of < 1 means there is a protective effect. • Standardised Mean Difference (SMD): Used for continuous outcomes (such as symptom scores). Mean differences in outcomes between groups are standardised to allow for different scoring methods. Negative SMDs are desirable. 12
  • 13. Relative risk of outcomes by interventions Beswick AD et al Complex interventions to improve physical function and maintain independent living in elderly people Lancet 2008;371:725-735 Study context Loss of physical function (SMD) People falling (RR) CGA older people -0.12 (-0.67 to 0.08) 0.76 (0.670.86) 0.98 (0.92-1.03) CGA frail older people -0.1 (-0.6 to 0.04) 0.99 (0.89 – 1.1) 0.90 (0.84-0.98) Falls prevention -0.25 (-0.36 to 0.13) 0.92 (0.870.97) 0.84 (0.61-1.16) All complex interventions -0.08 (-0.11 to 0.06) 0.90 (0.960.95) 0.94 (0.91-0.97) Hospital admission (RR) 13
  • 14. In summary • Some evidence that some targeted interventions in some health care systems may be effective in improving function. • Unclear what the effective ingredients of intervention are. • No real sense of cost-benefit of interventions. 14
  • 15. What is to be done? (in the conditions in which we find ourselves, not in the ones we would like) MRC approach to complex interventions • Conceptual modelling (can we see what to do?) • Proof of concept, case study (can we put it together?) • Pilot studies (can others do it?) • Rehearsal ‘trial’ (can it fit into an experiment?) • Full scale comparative study (does it work, is it harmful?) • Economic evaluation (is it worth it?) 15
  • 16. Who should do the developmental work? Will commissioners promote innovation? • High risk: naïve, credulous or conflicted commissioners Will commissioners and innovators work within an informed research and development culture? • Medium risk: commissioners make little use of CLAHRCs Will NHS funding streams support studies of innovation? • Low risk; central co-ordination of R&D funding 16
  • 17. WISH study (Well-being Interventions for Social & Health needs) • GP based tailored intervention aimed at 65+ age group • Multidimensional intervention ~ automated CGA with follow-up in practices • Four practices, urban & rural • GP Commissioners & local councils (Ealing & Hertfordshire) • Three University Departments : UCL (primary care, economics, environment) Herts (health services research, nursing) & Kings (social care, public involvement) • MRC funding for pilot study (2012-2014) 17
  • 18. Thank you for listening! s.iliffe@ucl.ac.uk 18