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A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms-8396

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A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms Martin Urschler, Stefan Kluckner, Horst Bischof Institute for Computer Graphics and Vision, Graz, University of Technology, Austria
Motivation Validation very difficult! ,[object Object],[object Object],[object Object],[object Object],We claim: Standardizing Evaluation Protocols at least as important as Developing Novel Methods! -> Put framework to discussion: - Open-source community effort - Instantiate framework by showing sample evaluation Presented algorithm at last years MICCAI. Nonlinear Image Registration
Contents ,[object Object],[object Object],[object Object],[object Object],[object Object]
The Nonlinear Registration Problem ,[object Object],h(x) Base Illustration taken from ITK Software Guide. SSD, NCC, Mutual Information, … B-Spline, Thin-Plate Spline, Def Field, … Gradient Descent, BFGS, … Intensity-Based, Feature-Based, …
Medical Applications of Nonlinear Image Registration ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Lung Perfusion for Pulmonary Embolism Detection [Wildberger et al.] Validation Study: Atlas-based Brain Volume Segmentation from MRI Images [Ng02] – taken from ITK Documentation Inter- & Intra-Modality Inter- & Intra-Subject No Ground Truth or Gold Standards Highly Ill-Posed How should we reach clinical acceptance?
Related Work on Evaluation (Frameworks) There exist some good ideas for evaluation in (Medical) Computer Vision! VALMET Segmentation Evaluation [Gerig et al] Community would benefit from open-source implementation! MICCAI 2007 Segmentation Challenge Workshop Multi-View 3D Reconstruction [Seitz et al] Stereo Reconstruction [Scharstein et al] Middlesbury Retrospective Evaluation of Intersubject Brain Registration [Hellier et al] Retrospective Rigid Registration Evaluation Project [West et al] NIREP (Inter-subject Brain-Registration Evaluation) [Christensen et al] Validation of Nonrigid Image Registration Using FEM [Schnabel et al] Segmentations are compared!
Open Science Evaluation Framework ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Registration Algorithms Public domain data sets Synthetic Deformations Similarity Measures Python Framework as Glue
Open Science Evaluation Framework
Synthetic Deformations Used ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Data Sets and Algorithms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Quantitative Measures ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
A Sample Evaluation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
A Sample Evaluation Simulated Data Difference to Original Standard Demons
A Sample Evaluation - Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Further Work ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Thank you for your attention!
 
 
 

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Nrrd to Dicom Conversion-3769Nrrd to Dicom Conversion-3769
Nrrd to Dicom Conversion-3769
 
Data Saving-3767
Data Saving-3767Data Saving-3767
Data Saving-3767
 
FreeSurfer Reader-3766
FreeSurfer Reader-3766FreeSurfer Reader-3766
FreeSurfer Reader-3766
 
Functional Magnetic Resonance Imaging Analysis-3765
Functional Magnetic Resonance Imaging Analysis-3765Functional Magnetic Resonance Imaging Analysis-3765
Functional Magnetic Resonance Imaging Analysis-3765
 
Diffusion Tensor Imaging Analysis-3749
Diffusion Tensor Imaging Analysis-3749Diffusion Tensor Imaging Analysis-3749
Diffusion Tensor Imaging Analysis-3749
 
Manual Segmentation-3747
Manual Segmentation-3747Manual Segmentation-3747
Manual Segmentation-3747
 
Data Loading and Visualization-3735
Data Loading and Visualization-3735Data Loading and Visualization-3735
Data Loading and Visualization-3735
 
Principles and Practices of Scientific Originology-8392
Principles and Practices of Scientific Originology-8392Principles and Practices of Scientific Originology-8392
Principles and Practices of Scientific Originology-8392
 
Principles and Practices of Scientific Originology-8391
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Principles and Practices of Scientific Originology-8391
 
ITK Tutorial Presentation Slides-953
ITK Tutorial Presentation Slides-953ITK Tutorial Presentation Slides-953
ITK Tutorial Presentation Slides-953
 
ITK Tutorial Presentation Slides-952
ITK Tutorial Presentation Slides-952ITK Tutorial Presentation Slides-952
ITK Tutorial Presentation Slides-952
 
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ITK Tutorial Presentation Slides-950
ITK Tutorial Presentation Slides-950ITK Tutorial Presentation Slides-950
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ITK Tutorial Presentation Slides-949ITK Tutorial Presentation Slides-949
ITK Tutorial Presentation Slides-949
 
ITK Tutorial Presentation Slides-948
ITK Tutorial Presentation Slides-948ITK Tutorial Presentation Slides-948
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ITK Tutorial Presentation Slides-947
ITK Tutorial Presentation Slides-947ITK Tutorial Presentation Slides-947
ITK Tutorial Presentation Slides-947
 
ITK Tutorial Presentation Slides-946
ITK Tutorial Presentation Slides-946ITK Tutorial Presentation Slides-946
ITK Tutorial Presentation Slides-946
 
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A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms-8396

  • 1. A Framework for Comparison and Evaluation of Nonlinear Intra-Subject Image Registration Algorithms Martin Urschler, Stefan Kluckner, Horst Bischof Institute for Computer Graphics and Vision, Graz, University of Technology, Austria
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  • 6. Related Work on Evaluation (Frameworks) There exist some good ideas for evaluation in (Medical) Computer Vision! VALMET Segmentation Evaluation [Gerig et al] Community would benefit from open-source implementation! MICCAI 2007 Segmentation Challenge Workshop Multi-View 3D Reconstruction [Seitz et al] Stereo Reconstruction [Scharstein et al] Middlesbury Retrospective Evaluation of Intersubject Brain Registration [Hellier et al] Retrospective Rigid Registration Evaluation Project [West et al] NIREP (Inter-subject Brain-Registration Evaluation) [Christensen et al] Validation of Nonrigid Image Registration Using FEM [Schnabel et al] Segmentations are compared!
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  • 13. A Sample Evaluation Simulated Data Difference to Original Standard Demons
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  • 17. Thank you for your attention!
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