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   5 weeks of gestation

   Afferent fibers from neuroblast located alongside
    neural tube

   Efferent fibers from neuroblast in the basal plate
    of tube from where they grow outside
   Afferent and efferent fibers join to form
    the nerve

   Nerves divide into anterior and posterior
    divisions

   There are connections between these
    nerves in the brachial plexus
   There are few terminal branches of the roots trunks
    and cords.

   ROOTS: a)dorsal scapular nerve b)branch to phrenic
    nerve c)Long thoracic nerve

   TRUNKS: a)nerve to subclavius b) suprascapular
    nerve

   CORDS: a) Lateral cord gives lateral pectoral nerve
    b)Posterior cord gives upper subscapular, lower
    subscapular and thoracodorsal nerve.
   Found in around 50%
   Most commonly pre-fixed(28-62%) and
    post-fixed(16-73%)
   Anatomy of rootlets, roots and vertebral foramen
    contribute to the type of injury

   Rootlets forming the cervical roots are intraspinal
    and lack connective tissue or meningeal envelope.

   Vulnerable to traction and susceptibility to avulsion
    at the level of cord.
   Fibrous attachment of spinal nerves to the
    transverse process seen in the 4th through 7th
    cervical roots

   This explains the high incidence of root avulsions
    in C8-T1 roots

   The spinal nerve able to move freely in the
    foramina due to non attachment to it
   Common :Birth injuries, motor vehicle
    trauma, sports injuries

    Rare :Gunshot wound, Stab injury
    Irradiation, Pancoast tumor

   Chronic microtrauma : Backpacker’s
    palsy, Painters
   Narakus' "law of seven seventies," based on experience
    with more than 1,000 patients over an 18-year
    span, estimates the current demographics:
   70% of traumatic brachial plexus injuries (BPIs) are due to
    motor vehicle accidents.
   70% of the vehicle accidents involve motorcycles or
    bicycles.
   70% of the cycle riders have associated multiple injuries.
   70% have a supraclavicular lesion.
   70% of those with supraclavicular lesions have at least one
    root avulsed.
   70% of patients with root avulsions have the lower roots
    (C7, C8, Tl or C8, Tl) avulsed.
   70% of patients with lower-root avulsions experience
    persistent pain
   Usually closed injuries
   95% traction injuries, 5% compression injuries
   Supraclavicular more common than infraclavicular
    involvement
   Roots and trunks most commonly involved
   Root avulsions: 2 mechanisms
                      peripheral- common
                      central- rare
   Infraclavicular injuries occur at cords or peripheral
    nerves and usually incomplete

   Caused by shoulder fracture or dislocation

   5- 25% of infraclavicular injuries are associated
    with axillary artery injury

   Penetrating injuries are usually infraclavicular
   in as many as one in 250 births

   High birth weight, prolonged labor,breech
    presentation, and shoulder dystocia

   Produced by traction on the neural elements for
    example, stretching of the brachial plexus with
    forced lateral flexion of the head and neck or
    excessive pull of limbs over head
   Pain, especially of the neck and shoulder
    Pain over a nerve common with rupture, as
    opposed to lack of percussion tenderness with
    avulsion
   Paresthesias and dysesthesias

   Weakness or heaviness in the extremity

   Diminished pulses, as vascular injury may
    accompany traction injury
   Sensory examination extremely important

    Deep pressure sensation may be the only clue to
    continuity in a nerve with no motor function or
    other sensation

    Apply full pinch to the nail base and pull the
    patient's finger outward ;any burning suggests
    continuity of the tested nerve
   According to the location of injury, extension
    throughout the plexus, and the degree of the
    damage

   Based on a thorough physical examination, BPI
    divided into preganglionic and postganglionic
    injuries.

   Prognostic and therapeutic implications
   Avulsion of the nerve root proximal to the spinal
    ganglion

   Dorsal rami interrupted, denervation of dorsal neck
    muscles ( rhomboids, serratus anterior, ) Changes
    in EMG
   No proximal stump or neuroma formation, No Tinel
    sign present

   Meningocele formation due to dural and arachnoid
    lesion with avulsed roots

   Myelographic leak

   Roots not visible on CT
   Associated Horner's syndrome or a fracture of the
    transverse process of the adjacent cervical vertebra

   Nerve fibres to skin in continuity with neurons in
    the spinal ganglion

   No wallerian degeneration of sensory nerve fibres

   Positive nerve conduction
   Depending on the number of roots
    avulsed, Preganglionic BPI generally falls into one
    of three categories:

   A completely flail arm with avulsion of all roots
    (C5-T1)

   A lower avulsion of the C8-T1 roots

   An upper lesion in which only the C5 and C6 roots
    avulsed
   Limb extended at the elbow, flaccid at the side of
    the trunk, and adducted and internally rotated

    Paralysis of the supinator muscle causes pronation
    deformity of the forearm and inability to supinate
    the forearm.

   Sensation absent over the deltoid muscle and the
    lateral aspect of the forearm and hand.
   Segmental sensory and motor deficits involving C8
    and T1


   The primary dysfunction : apparent in the intrinsic
    musculature of the hand along with paralysis of the
    wrist and finger flexors
   The sensory deficit along the medial aspect of the
    arm, forearm, and hand
   Distal to the spinal ganglia (proximal stump with
    neuroma formation)

   Tinel’s sign positive, myelography negative, EMG
    normal, roots visible on CT, Nerve conduction
    abnormal

    Postganglionic injuries further subdivided into
    trunk and cord injuries
   Elicited by placing a drop of histamine on the skin
    along the distribution of the nerve being examined
   Skin scratched through the drop of histamine :
    cutaneous vasodilation, wheal formation, and flare
    response
   Nerve interrupted proximal to the ganglion
    :anesthesia along its cutaneous course, normal
    axon response
   Injury is distal to the ganglion : anesthesia along
    the course of the nerve, and vasodilation and wheal
    formation seen, flare response absent
   Long thoracic nerve ( serratus anterior muscle)
    intact
   Suprascapular nerve involved

   Upper trunk lesions ( paralysis of shoulder
    muscles & biceps brachii)
   Middle trunk lesions :Radial nerve palsy
   Lower trunk lesions: ulnar & median nerve palsy
   Long thoracic nerve, Suprascapular nerve &
    pectoral nerve intact




   Posterior, lateral cord & medial cord lesions
   Motor and sensory deficits in the distribution of :

    musculocutaneous nerve (paralysis of the biceps)
    lateral root of the median nerve (paralysis of the
    flexor carpi radialis and pronator teres)
   lateral pectoral nerve (clavicular head of the
    pectoralis major).
   Sensory deficit over the anterolateral aspect of the
    forearm in the relatively small autonomous zone of
    the musculocutaneous nerve
   Subscapular (paralysis of the subscapularis and
    teres major)

   Thoracodorsal (paralysis of the latissimus dorsi)

   Axillary (paralysis of the deltoid and teres minor)
   Radial (paralysis of extension of the
    elbow, wrist, and fingers)

    Sensory loss in the autonomous zone of the
    axillary nerve overlying the deltoid muscle
   Motor deficit of a combined ulnar and median
    nerve lesion (except for the flexor carpi radialis and
    pronator teres)



   Extensive sensory loss along the medial aspect of
    the arm and hand
   Upper plexus lesions (C5, C6)

   Extended upper plexus (C5,C6,C7 )

   C7 Lesions

   Lower plexus lesions (C8, T1 )

   Peripheral lesions
Seddon’s classification:

   Neurapraxia ( traction/ compression, recovery is
    rule )

   Axonotmesis ( section of nerve with intact
    sheath, wallerian degeneration, recovery in 6/8
    weeks)

   Neurotmesis (complete section, surgical repair)
   Radiographic evaluation
    ◦ In anteroposterior (AP) chest radiography, specific
      attention directed to the distance between the
      spinous processes of the thoracic spine and the
      scapula

    ◦ If the radiograph not malrotated, an increase in
      this distance compared with the contralateral side
      may indicate scapulothoracic dissociation
   Gold standard

   The most reliable indicator of root avulsion : an
    absent root shadow on plain myelography
   A common sign of a root avulsion: meningocele at
    the affected level
   Delayed for 4 weeks so that any blood clot will not
    be dislodged by the study and the meningocele can
    be allowed to form
   Fast spin echo (FSE-MR)

   Useful in infants with obstetric palsy

   Noninvasive and can be performed under sedation

   Postmyelography MRI and CT : mainstays of
    imaging brachial plexus injuries
   Confirm a diagnosis

   Localize lesions

   Define severity of axon loss and completeness of
    lesion

   Serve as an important adjunct to thorough
    history, physical exam and imaging study
   For closed injuries EMG and NCV best performed 3
    to 4 weeks after the injury because wallerian
    degeneration will occur by this time
   Denervation changes(fibrillation potentials) seen in
    proximal muscles 10 to 14 days and 3 to 6 weeks
    post injury in most distal muscles

   Reduced MUP(motor unit potential) recruitment
    shown immediately after weakness from LMN injury

   Presence of active motor units with voluntary effort
    and few fibrillations at rest good prognosis

   Distinguishing preganglionic from postganglionic
    lesions
   NAP (nerve action potential )



   SEP (somatosensory evoked potential)



   CMAP (compound muscle action potential)
   Differentiates preganglionic from postganglionic
    injuries

    If the injury proximal to the dorsal root ganglion
    (DRG), no Wallerian degeneration; a SNAP observed
    in a nerve with an anesthetic dermatome confirms
    a preganglionic lesion
   SNAPs not useful for C5 evaluation, C5 does not
    provide a significant contribution to a major
    peripheral sensory nerve
   Intraoperative SSEPs are useful in brachial
    plexus surgery.
    The presence of suggests continuity
    between the peripheral nervous system and
    the CNS via the DRG.
   Absent in postganglionic or combined pre-
    and postganglionic lesions.
   A - acute exploration
•     concomitant vascular injury
•     open injury by sharp laceration
•     crush or contaminated wound

   Open injury with low-velocity missile
•   Early exploration not indicated, unless injuries to
    adjacent vessels or viscera make immediate
    treatment necessary
•   Condition of the patient prevents extensive repair
    or grafting of the plexus
•    Injury inspected, its extent documented &
    observed
   A correct diagnosis of the amount of damage to
    the plexus established only by exploration.

   Functional assessment of the nerve made by intra-
    operative nerve stimulation

    A non-conducting neuroma resected and the gap
    reconstructed with nerve grafts
   B - early exploration (1- 2 weeks)

•   Unequivocal complete C5- T1 avulsion injuries
•   Facilities not available at initial exploration
•   Concomitant injuries requiring early care
   Complete injuries with no recovery by clinical
    examination or EMG at 12 weeks post injury


   Distal recovery without regaining clinical or
    electrical evidence of proximal muscle function

   Any return has ceased

   Patient shows non-anatomical return of function
    with isolated lack of proximal function in the
    presence of good distal nerve recovery
    Evidence that the lesions at the postganglionic
    level

   Anaesthetic limb, severe deafferentation
    pain, Horner’s syndrome and pseudomeningoceles
    on imaging
   Postganglionic lesions :follow patients
    conservatively for up to 3 months to watch for
    spontaneous motor recovery. In upper-plexus
    injuries, if the biceps muscle not recovered within
    3 months, then surgical exploration
   Stretch neurapraxia may regenerate healthy nerve
    tissue

   Observation & physical therapy up to 8-10 weeks
    for spontaneous recovery

   After 4 weeks a baseline electromyography and
    CT/MR myelography should be performed.
   Restoration of elbow flexion

   Restoration of shoulder abduction

   Restoration of sensation to the medial border of
    the forearm and hand
   Neurolysis
   Nerve repair
•      Neurorrhaphy
•      End to side coaptation
   Nerve graft
   Nerve transfer or neurotization
   Functional free muscle transfer
   Carlstedt et al :reimplantation of avulsed roots
   Direct intraoperative nerve stimulation and
    recording required across damaged elements
•   If nerve action potentials are obtained, simple
    neurolysis indicated.
•   If neural integrity completely lost, or if no nerve
    action potentials recorded across a damaged
    element, excision and nerve grafting are required
   In root avulsions of the upper plexus in which no
    proximal neural stump is available for nerve
    grafting, neurotization between the intercostal
    nerves and the musculocutaneous nerve to restore
    elbow flexion
   Effective only if scar tissue seen around nerve or
    inside epineurium, preventing recovery or causing
    pain



   Pre and post neurolysis direct nerve stimulation is
    mandatory to evaluate improvement in nerve
    conduction
   Sharp transection with excellent fascicular pattern
    and minimal scar



   Lesions of the C5 and C6 nerve roots, the upper
    trunk, and the lateral cord proximal to the origin of
    the musculocutaneous nerve can be treated with
    some success
   Excellent in small nerves with one function
   Viterbo :BR J Plast surg 1994

   Denervated nerve brought with its cross section
    end to side with innervated nerve with creation of
    epineural/perineural windows
   Indicated for well defined nerve ends without
    segmental injuries

   Intraoperatively a good fascicular pattern should be
    seen after the neuroma excision
   Possible sources: sural, brachial cutaneous
    nerve, radial sensory and possibly ulnar nerve
   Before implantation graft orientation reversed to
    minimize axonal branch loss
   Surgical technique the most important factor in
    nerve graft
   A tension free nerve graft better than a primary
    repair under tension

   Thin cutaneous grafts (e.g. sural nerve) prepared

   Graft should be 20% longer than the length of the
    nerve defect

   Endoscopic harvesting of the sural nerve graft
    devise to overcome the potential drawbacks of the
    open technique
   Mackinnon et all

   Act as a temporary scaffold across which axons
    regenerate

   Ultimately, the allograft tissue completely replaced
    with host material

   Tacrolimus, greater potential and fewer side
    effects than other
    immunosuppressants, neuroregenerative and
    neuroprotective effects
   Nerve repairs performed with fibrin sealants
    produced less inflammatory response and
    fibrosis, better axonal regeneration, and better
    fiber alignment than the nerve repairs performed
    with microsutures alone

   Fibrin sealant techniques were quicker and easier
    to use



     * J oint Reconstr Microsurg 2006
   Help in directing axonal sprouts from the proximal
    stump to the distal nerve stump

   Provide a channel for diffusion of neurotropic and
    neurotrophic factors and minimize infiltration of
    fibrous tissue

   Tubes made of biological materials such as
    collagen have been used with more success for
    distances of less than 3 cm

   *PS Bhandari, LP Sadhotra, P Bhargava, AS Bath, MK Mukherjee, Pauline Babu Indian Journal of
    Neurotrauma (IJNT), Vol. 5, No. 1, 2008
   For repair of severe brachial plexus injury, in which
    the proximal spinal nerve roots have been avulsed
    from the spinal cord

   Ideally performed before 6 months post injury but
    may be better suited than grafting in situation after
    the preferred 6 months time frame

   A proximal healthy nerve coapted to the
    denervated nerve to reinnervate the latter by the
    donated axons
   The concept is to sacrifice the function of a lesser
    valued donor muscle to revive the function in the
    recipient nerve and muscle that will undergo
    reinnervation

   Transferring a pure motor donor nerve to a motor
    recipient nerve gives the best result of motor
    neurotization, for example, spinal accessory to
    suprascapular neurotization
   Recipient site at the peripheral part of the plexus
    such as the musculocutaneous nerve, the
    suprascapular nerve, or the axillary nerve more
    effective than a recipient in the central part such as
    the posterior cord or the lower trunk

   Reinnervate the recipient nerve as close to the
    target muscle as possible; ex. transfer of an ulnar
    nerve fascicle directly to the biceps branch of the
    musculocutaneous nerve in close proximity to its
    entry into the muscle Frederic et all
   Direct suture without tension always superior to
    indirect suture with a nerve graft

   Especially true for the weak donor nerves such as
    intercostal nerves and the distal spinal accessory
    nerve

   Ipsilateral nerve transfer always superior to the
    contralateral nerve transfer

   Current trends in the management of brachial plexus injuries Indian Journal of Neurotrauma (IJNT), Vol.
    5, No. 1, 2008
   A- intraplexal

   B- extraplexal

   Plexoplexal options are undamaged roots
   The transfer of a spinal nerve or more distal plexus
    component with intact spinal cord connections to a
    more important denervated nerve

   Ruptured proximal nerve used

   Examples include connecting the proximal stump
    of C5 or C6 to the distal aspect of C8, lower
    trunk, or median nerve, or the use of a portion of a
    functional ulnar nerve to the musculocutaneous
    nerve
   Transfer of a non brachial plexus component nerve
    to the brachial plexus



   Sources commonly used include spinal accessory
    nerve, intercostal nerves, phrenic nerve, deep
    cervical motor branches, and contralateral C7
    transfer
   Neuromuscular neurotization (direct implantation
    of motor nerve fascicles in to denervated muscle)
    from intraplexal sources
   Spinal accessory to surprascapular or
    musculocutaneous
   Phrenic to axillary nerve
   Intercostal to musculocutaneous long
    thoracic, radial and median nerve
   Long head of triceps nerve to anterior branch of
    axillary nerve
   Partial ulnar nerve transfer for elbow flexion
   The contralateral C7 transfer preferred for hand
    flexors and sensation in global plexopathies
   Through a lateral fourth-rib thoracotomy the motor
    portion of the third, fourth, and fifth intercostal
    nerves transferred subcutane-ously into the axilla
    to be anastomosed to the musculocutaneous nerve
   If the interval from BPI to reconstruction delayed
    beyond 12 months, the results of surgical
    reconstruction with the intercostal nerves alone
    have been poor
   Attributed to fibrosis of the motor end plates of the
    biceps muscle.
   Under these circumstances, a free innervated
    gracilis muscle to replace the biceps
   Attachment is made proximally with the gracilis
    origin to the coracoid process and distally to the
    biceps tendon. After successful vascular
    anastomosis of the artery and vein, through an
    ipsilateral thoracotomy, intercostal motor nerves to
    the third, fourth, and fifth ribs are used to
    successfully reinnervate the gracilis
   For upper trunk injury with intact lower trunk: 1 to
    2 fascicles of ulnar nerve anastomosed to biceps

   Contra lateral C7 used in pan brachial plexopathy
    with multiple avulsions and limited donor
    possibility
   Contra lateral C7 root extended by means of
    vascularised ulnar nerve graft in patient with C8 T1
    avulsion and median nerve is the most frequent
    recipient

   Another option is transferring nerve to long head
    of triceps to anterior branch of axillary nerve
   After brachial plexus repair and reconstruction, 12
    to 18 months required to determine the extent of
    neural regeneration



   If recovery considered inadequate, peripheral
    reconstruction considered
   The choice of the donor muscle-tendon unit or
    units not interfere with existing function
   Adequate strength (a grade of at least 4 of 5) of the
    donor muscle must be confirmed
   Avoid transferring a tendon when the muscle of
    that tendon was previously paralyzed and has now
    recovered.
   The excursion of the donor muscle-tendon unit
    must be adequate
   Each tendon perform only one function
   The transfer employs a straight line of pull
   When possible, synergism should be employed
    such that the simultaneous contractions of
    different muscles combine to achieve a desired
    function
   Manual or electrodiagnostic testing to check for
    inphase firing of planned donors with
    nearby, uninvolved motors should be performed
    preoperatively, to ensure that transferred motors
    and intact motors do not act as antagonists and
    prevent active motion
   Functional range of motion
   Joint contractures released
   The joint congruent and reduced
   Skin supple without constricting scars

   Trapezius-to-deltoid transfer as described by Saha
    to improve abduction and latissimus dorsi transfer
    to improve external rotation as described by
    L'Episcopo
   Deltoid and the clavicular head of the pectoralis
    major as prime movers for abduction; they also lift
    the humeral shaft
   Subscapularis, supraspinatus and infraspinatus are
    a steering group which stabilise the humeral head
    in the glenoid.
   The sternal head of pectoralis major, latissimus
    dorsi, teres major and teres minor form a
    depressor group which alsorotate the shaft and
    pull the humeral head downwards during the last
    few degrees of abduction.
   When any two of the steering group of muscles
    were paralysed a single muscle transfer to replace
    the deltoid would not provide abduction beyond
    90°
   Transfer of pectoralis minor, the upper two
    digitations of serratus anterior, latissimus dorsi
    and teres major in various combinations.
   Transfers of the levator
    scapulae, sternocleidomastoid, scalenus
    anterior, scalenus medius and scalenus capitis
   Saha’s logical modification of the trapezius transfer
    described by Bateman
   Provides a more distal fixation of the transfer after
    a more proximal release.
   Greater lever arm, and fracture of the bony
    insertion transferred from the acromion allows
    better fixation to the narrow cylindrical shaft of the
    humerus.
    An important modification to consider transfer for
    paralysed musclesof the rotator cuff, to improve
    control of the humeral head and prevent
    subluxation
   Adduction and internal rotation contracture
    :Release or recession of subscapularis muscle

   Isolated abduction contracture: Release or
    recession of deltoid muscle

   Abduction and external rotation contracture:
    Transfer of infraspinatus tendon to teres minor
    tendon;release or recession of infraspinatus and
    supraspinatus tendons with or without release of
    deltoid muscle
   Dysfunction of anterior and middle parts of deltoid
    muscle (partial reinnervation of paralyzed deltoid
    muscle) :Anterior transfer of posterior part of
    deltoid muscle

   Dysfunction of supraspinatus or infraspinatus
    muscle :Transfer of latissimus dorsi tendon to
    greater tuberosity
   Dysfunction of deltoid muscle Transfer of trapezius
    muscle with bone to lateral aspect of humerus;
    bipolar transfer of latissimus dorsi muscle
   Dysfunction of subscapularis muscle :Transfer of
    serratus anterior muscle; transfer of
    pectoralismajor tendon

   Internal or external rotation deformity with
    incongruent glenohumeral joint :Humeral
    derotation osteotomy

   Severe dysfunction of shoulder with pain or
    instability :Glenohumeral arthrodesis
   Reviewed 26 patients treated by trapezius transfer
    for deltoid paralysis due to brachial plexus injury
    or old poliomyelitis.
   Assessed the power of shoulder abduction and the
    tendency for subluxation.
    Good results in 16 patients (60%); five were fair
    and five poor.
   Trapezius transfer appears to give reasonable
    results in the salvage of abductor paralysis of the
    shoulder.
   J Bone Joint Surg [Br] 1998;80-B:114-6.
   Division of the clavicle
    and the acromion to
    allow transfer of the
    insertion of the central
    part of the trapezius
   The transfer unit is
    fixed to the humeral
    shaft with screws
   Radiograph after
    operation
Active abduction before   Active abduction after
surgery.                  surgery.
   Failure due to
    persistent anterior
    subluxation after
    trapezius transfer
    Severe combined lesions and the surgeon cannot
    reasonably expect to achieve glenohumeral
    stability with any of the described soft-tissue
    procedures

   To enhance the power of weak elbow flexion or
    extension transfers by isolating the forces of the
    transfer to the elbow
   Fusion in this attitude permits scapular
    motion, when combined with elbow motion, to
    allow the patient to reach all four major functional
    areas: face, midline, perineum, and rear trouser
    pocket
   Restoration of elbow flexion primary importance

   Elbow flexion restored by intercostal neurotization
    or tendon transfer.
    When the pectoralis major and latissimus dorsi
    areavailable for transfer, superior results
    anticipated
   Dysfunction of biceps muscle :Unipolar or bipolar
    transposition of pectoralis major muscle; bipolar
    transposition of latissimus dorsi muscle; free
    microvascular transfer of gracilis rectus
    muscle;modified Steindler flexorplasty; anterior
    transfer of triceps tendon

   Dysfunction of triceps muscle :Transfer of
    latissimus dorsi muscle
   When the medial epicondylar muscles a weak or full
    extension of the elbow essential for transfer or
    ambulation, an alternative procedure considered

   Steindler's procedure when the elbow flexors reach
    only grade 2, contrarily contraindicated when the
    elbow flexors are classified as grade 0, when the
    wrist flexors are weak, or when wrist and finger
    extensors are paralyzed
   proximal transfer (4 –
    5 cm) and fixation of a
    piece of the medial
    epicondyle with its
    attached origin of the
    flexor-pronator muscle
    group in the middle of
    the anterior aspect of
    the humerus.
   Liu TK. Yang RS. Sun JS. Clinical Orthopaedics & Related Research. (296):104-8, 1993 Nov

    Seventy-one consecutive patients treated with a modified
    Steindler flexorplasty from 1970 to 1987. Additional
    operative procedures included shoulder fusion (45
    patients), tendon transfer (20 patients), and wrist
    tenodesis (3). Follow-up averaged 8.2 years. The outcome
    excellent in 32%, good in 47%, fair in 13%, and poor in 8%.
    Postoperatively, the mean arc of active elbow flexion 114
    degrees; the average elbow extension loss, 28 degrees;
    the mean active pronation, 74 degrees; and supination, 30
    degrees. Wire breakage found in two cases. Additional
    tendon transfer of flexor carpi ulnaris to extensor carpi
    radialis brevis improved the outcomes in the patients
    without active supination.
   The modified Steindler flexorplasty provided predictable
    functional improvement in carefully selected patients with
    paralyzed upper extremities.
   An early but cosmetically unacceptable procedure :
    transfer of the sternocleidomastoid muscle which
    involves detaching this muscle from its insertion
    and linking it to the insertion of the biceps muscle
    by means of a long strip of fascia lata
Extension   Flexion
Flexion   Extension
   In hands in which the superficial flexors of the
    fingers and thenar muscles of opposition
    denervated, usually as the result of high median-
    nerve or brachial plexus injury, thumb opposition
    restored by transfer of the superficial flexor of the
    ring finger to the thumb through a dynamic pulley
    made from the distal segment of flexor carpi
    ulnaris which is attached to the extensor carpi
    ulnaris, combined with transfer of the proximal
    segment of flexor carpi ulnaris to the transferred
    paralyzed superficial ring-finger flexor tendon
   C5-6 type :

    complete loss of voluntary shoulder and elbow
    control, although many can still extend the wrist by
    using finger extensors and the extensor carpi
    ulnaris. Thumb and index finger sensation
    impaired
   Figure-of-8 harness and Bowden cable a used to
    provide body-powered elbow flexion, sometimes
    with an elbow hinge that can be locked in several
    positions; Shoulder subluxation also reduced by su
   C5-7 type

   adds radial palsy to the above picture, sensory loss
    in the hand increase, but all active extension at the
    wrist, hand, and fingers lost
   Possible to add either static or spring-assisted
    wrist, hand, and finger extension to the previous
    orthosis.
   c7- 8 Tl type

   Good shoulder and elbow function but loses finger
    flexors, extensors, and intrinsics

   Surgical reconstruction often of particular value

   Those who sustain a concomitant traumatic
    transradial amputation : body-powered or switch-
    controlled terminal device
   C8, Tl type

    Enjoys the greatest percentage of orthotic success
    since motor rather than sensory loss significant

    Although finger flexors and intrinsics are
    paralyzed, sensory loss is limited to the ring and
    small digits, which are not involved in pinch
    prehension
   In view of the substantial percentage of BPI
    amputees who reject prosthetic devices, it has been
    argued that orthotic restoration is an equally
    plausible alternative. Wynn Parry has reported his
    experience with a series of over 200 cases and
    states that 70% continue to use a full-arm orthosis
    for work or hobby activities after 1 year

   Wynn Parry CB: Rehabilitation of patients following traction lesions of the brachial plexus. Clin Plast Surg 1984
    A thorough physical examination including manual and
    EMG muscle testing required to assess rehabilitation
    potential.
   The patient actively involved in all prescription decisions
    from the outset; without a motivated and cooperative
    individual, even heroic prosthetic/orthotic interventions
    are doomed to failure.
   Full-arm orthosis during the recovery period, beginning as
    soon as the patient has come to terms with the serious
    and potentially permanent nature of his injuries.
   Once surgical reconstruction and spontaneous recovery
    are complete, amputation and trial with a prosthesis can
    be considered.
   Psychological and social work consultation may be useful
    to help the patient discuss the altered body image and
    employment possibilities that will follow amputation.
    Most of these injuries resolve without operative
    intervention

   Joint mobilization and range-of-motion exercises
    performed by the parents and guided by a physical
    or occupational therapist can help to maintain a
    congruent glenohumeral joint and to minimize
    contractures

   For severely affected, however, a variety of
    procedures are available
   3-9 mnths : Exploration and repair of brachial
    plexus

   12-24 nths : Release of contractures

   24-60 mnths : Tendon and muscle transfers
   >60 (and incongruent joint) :Osseous procedures
   As long as the glenohumeral joint is
    congruent, tendon and muscle transfers may be
    performed at a later date, but they should be
    considered at these earlier times to maximize
    functional recovery

   Joint incongruity increase with the patient’s age

   Patients with incomplete recovery who are seen
    more than six months after birth frequently have
    muscle contractures due to unopposed muscle
    forces and are no longer candidates for direct
    repair of the plexus
   Performed in patients first seen when they are
    older than five years of age

   Humeral rotational osteotomy for persistent
    internal rotation contracture and glenohumeral
    arthrodesis in the setting of severe
    pain, instability, or arthritic changes

    For posterior dislocation of the humeral head
    :posterior capsular plication
   Highly dependent on pattern of injury
   Complete C4 to T1 injuries a considered most
    severe and virtually irreparable

   Avulsion injuries from C5 toT1 amenable to
    restoration of shoulder and elbow function only

   Ideal candidate for surgery are patients with
    proximal rupture or avulsion and sparing of lower
    trunk
   Since 1995 to 2002 , 505 patients studied for
    functional and occupational outcome after surgery
    for BPI
   In India BPI most common due to RTA with Rt side
    involved in 2/3
   40% cases have pan BPI
   85% of cable graft yielded improvement in motor
    power compared 68% in neurotized nerve and 66%
    in patients undergoing neurolysis
   Most effective donor nerve for musculocutaneous
    neurotization was medial pectoral nerve (63.6%)
    patient improved

   Accessory nerve was most effective for
    neurotization of suprascapular nerve (100%)

   Thoracodorsal axillary neurotization gave (66.7%
    improvement)

   50% patients either remained unemployed or had
    to change there jobs
   Sedel reported results of surgical treatment of 63
    traumatic brachial plexus palsies, 32 complete and
    31 partial.
   Of the 32 complete palsies, 26 had repair
    procedures; 21 were improved.
    Of the 31 partial palsies, 23 had repair
    procedures, and 20 were improved.
    Results of nerve transfer were disappointing
   Solonen et al. reviewed 52 brachial plexus injuries
    treated surgically :Grafts used in 24
    avulsions, neurolyses in 14, direct suture in 2, and
    intercostal neurotization in 12.
    Good results seen in 19 patients after fascicular
    grafting with return of function of the biceps
    muscle.
   Neurotization produced function in 4 of 12
    patients.
   Narakas reported surgical treatment by
    repair, grafting, or neurolysis in 164 patients with
    traction injuries and found that 85% of 20 patients
    with infraclavicular injuries improved after
    surgery, and that only 55% of 58 patients with
    supraclavicular injuries improved
   Barnes found that 13 patients with plexus injuries
    but without EMG evidence of degenerative changes
    at 3 weeks recovered rapidly and completely.
    Of 33 patients with upper plexus injuries, 22
    spontaneously regained significant function of the
    muscles of the shoulder, elbow, and wrist. Of 26
    with lower plexus injuries, 18 regained some
    proximal muscle function.
   In 1977, Millesi, using the interfascicular
    autogenous nerve grafting technique, reported
    return of M3 or better power (Highet) in 38 (70%) of
    54 patients
    In 1984, Millesi :134 patients with complete
    brachial plexus lesions treated with
    neurolysis, nerve grafting, and neurotization.
    Useful function was regained in 47 of 65 patients
    (72%) after nerve grafting. In 72 patients with injury
    to the upper plexus only, useful function returned
    in 21 of 28 patients (75%) after nerve grafting
Thank you

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Brachial plexus injury

  • 1.
  • 2. 5 weeks of gestation  Afferent fibers from neuroblast located alongside neural tube  Efferent fibers from neuroblast in the basal plate of tube from where they grow outside
  • 3. Afferent and efferent fibers join to form the nerve  Nerves divide into anterior and posterior divisions  There are connections between these nerves in the brachial plexus
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10. There are few terminal branches of the roots trunks and cords.  ROOTS: a)dorsal scapular nerve b)branch to phrenic nerve c)Long thoracic nerve  TRUNKS: a)nerve to subclavius b) suprascapular nerve  CORDS: a) Lateral cord gives lateral pectoral nerve b)Posterior cord gives upper subscapular, lower subscapular and thoracodorsal nerve.
  • 11.
  • 12.
  • 13. Found in around 50%  Most commonly pre-fixed(28-62%) and post-fixed(16-73%)
  • 14.
  • 15.
  • 16. Anatomy of rootlets, roots and vertebral foramen contribute to the type of injury  Rootlets forming the cervical roots are intraspinal and lack connective tissue or meningeal envelope.  Vulnerable to traction and susceptibility to avulsion at the level of cord.
  • 17. Fibrous attachment of spinal nerves to the transverse process seen in the 4th through 7th cervical roots  This explains the high incidence of root avulsions in C8-T1 roots  The spinal nerve able to move freely in the foramina due to non attachment to it
  • 18. Common :Birth injuries, motor vehicle trauma, sports injuries  Rare :Gunshot wound, Stab injury Irradiation, Pancoast tumor  Chronic microtrauma : Backpacker’s palsy, Painters
  • 19. Narakus' "law of seven seventies," based on experience with more than 1,000 patients over an 18-year span, estimates the current demographics:  70% of traumatic brachial plexus injuries (BPIs) are due to motor vehicle accidents.  70% of the vehicle accidents involve motorcycles or bicycles.  70% of the cycle riders have associated multiple injuries.  70% have a supraclavicular lesion.  70% of those with supraclavicular lesions have at least one root avulsed.  70% of patients with root avulsions have the lower roots (C7, C8, Tl or C8, Tl) avulsed.  70% of patients with lower-root avulsions experience persistent pain
  • 20. Usually closed injuries  95% traction injuries, 5% compression injuries  Supraclavicular more common than infraclavicular involvement  Roots and trunks most commonly involved  Root avulsions: 2 mechanisms peripheral- common central- rare
  • 21.
  • 22. Infraclavicular injuries occur at cords or peripheral nerves and usually incomplete  Caused by shoulder fracture or dislocation  5- 25% of infraclavicular injuries are associated with axillary artery injury  Penetrating injuries are usually infraclavicular
  • 23.
  • 24.
  • 25. in as many as one in 250 births  High birth weight, prolonged labor,breech presentation, and shoulder dystocia  Produced by traction on the neural elements for example, stretching of the brachial plexus with forced lateral flexion of the head and neck or excessive pull of limbs over head
  • 26.
  • 27. Pain, especially of the neck and shoulder  Pain over a nerve common with rupture, as opposed to lack of percussion tenderness with avulsion  Paresthesias and dysesthesias  Weakness or heaviness in the extremity  Diminished pulses, as vascular injury may accompany traction injury
  • 28. Sensory examination extremely important  Deep pressure sensation may be the only clue to continuity in a nerve with no motor function or other sensation  Apply full pinch to the nail base and pull the patient's finger outward ;any burning suggests continuity of the tested nerve
  • 29. According to the location of injury, extension throughout the plexus, and the degree of the damage  Based on a thorough physical examination, BPI divided into preganglionic and postganglionic injuries.  Prognostic and therapeutic implications
  • 30.
  • 31. Avulsion of the nerve root proximal to the spinal ganglion  Dorsal rami interrupted, denervation of dorsal neck muscles ( rhomboids, serratus anterior, ) Changes in EMG
  • 32. No proximal stump or neuroma formation, No Tinel sign present  Meningocele formation due to dural and arachnoid lesion with avulsed roots  Myelographic leak  Roots not visible on CT
  • 33.
  • 34. Associated Horner's syndrome or a fracture of the transverse process of the adjacent cervical vertebra  Nerve fibres to skin in continuity with neurons in the spinal ganglion  No wallerian degeneration of sensory nerve fibres  Positive nerve conduction
  • 35.
  • 36. Depending on the number of roots avulsed, Preganglionic BPI generally falls into one of three categories:  A completely flail arm with avulsion of all roots (C5-T1)  A lower avulsion of the C8-T1 roots  An upper lesion in which only the C5 and C6 roots avulsed
  • 37. Limb extended at the elbow, flaccid at the side of the trunk, and adducted and internally rotated  Paralysis of the supinator muscle causes pronation deformity of the forearm and inability to supinate the forearm.  Sensation absent over the deltoid muscle and the lateral aspect of the forearm and hand.
  • 38. Segmental sensory and motor deficits involving C8 and T1   The primary dysfunction : apparent in the intrinsic musculature of the hand along with paralysis of the wrist and finger flexors  The sensory deficit along the medial aspect of the arm, forearm, and hand
  • 39. Distal to the spinal ganglia (proximal stump with neuroma formation)  Tinel’s sign positive, myelography negative, EMG normal, roots visible on CT, Nerve conduction abnormal  Postganglionic injuries further subdivided into trunk and cord injuries
  • 40. Elicited by placing a drop of histamine on the skin along the distribution of the nerve being examined  Skin scratched through the drop of histamine : cutaneous vasodilation, wheal formation, and flare response  Nerve interrupted proximal to the ganglion :anesthesia along its cutaneous course, normal axon response  Injury is distal to the ganglion : anesthesia along the course of the nerve, and vasodilation and wheal formation seen, flare response absent
  • 41. Long thoracic nerve ( serratus anterior muscle) intact  Suprascapular nerve involved  Upper trunk lesions ( paralysis of shoulder muscles & biceps brachii)  Middle trunk lesions :Radial nerve palsy  Lower trunk lesions: ulnar & median nerve palsy
  • 42. Long thoracic nerve, Suprascapular nerve & pectoral nerve intact  Posterior, lateral cord & medial cord lesions
  • 43. Motor and sensory deficits in the distribution of :  musculocutaneous nerve (paralysis of the biceps)  lateral root of the median nerve (paralysis of the flexor carpi radialis and pronator teres)  lateral pectoral nerve (clavicular head of the pectoralis major).  Sensory deficit over the anterolateral aspect of the forearm in the relatively small autonomous zone of the musculocutaneous nerve
  • 44. Subscapular (paralysis of the subscapularis and teres major)  Thoracodorsal (paralysis of the latissimus dorsi)  Axillary (paralysis of the deltoid and teres minor)  Radial (paralysis of extension of the elbow, wrist, and fingers)  Sensory loss in the autonomous zone of the axillary nerve overlying the deltoid muscle
  • 45. Motor deficit of a combined ulnar and median nerve lesion (except for the flexor carpi radialis and pronator teres)  Extensive sensory loss along the medial aspect of the arm and hand
  • 46. Upper plexus lesions (C5, C6)  Extended upper plexus (C5,C6,C7 )  C7 Lesions  Lower plexus lesions (C8, T1 )  Peripheral lesions
  • 47. Seddon’s classification:  Neurapraxia ( traction/ compression, recovery is rule )  Axonotmesis ( section of nerve with intact sheath, wallerian degeneration, recovery in 6/8 weeks)  Neurotmesis (complete section, surgical repair)
  • 48.
  • 49. Radiographic evaluation ◦ In anteroposterior (AP) chest radiography, specific attention directed to the distance between the spinous processes of the thoracic spine and the scapula ◦ If the radiograph not malrotated, an increase in this distance compared with the contralateral side may indicate scapulothoracic dissociation
  • 50. Gold standard  The most reliable indicator of root avulsion : an absent root shadow on plain myelography  A common sign of a root avulsion: meningocele at the affected level  Delayed for 4 weeks so that any blood clot will not be dislodged by the study and the meningocele can be allowed to form
  • 51.
  • 52. Fast spin echo (FSE-MR)  Useful in infants with obstetric palsy  Noninvasive and can be performed under sedation  Postmyelography MRI and CT : mainstays of imaging brachial plexus injuries
  • 53. Confirm a diagnosis  Localize lesions  Define severity of axon loss and completeness of lesion  Serve as an important adjunct to thorough history, physical exam and imaging study
  • 54. For closed injuries EMG and NCV best performed 3 to 4 weeks after the injury because wallerian degeneration will occur by this time
  • 55. Denervation changes(fibrillation potentials) seen in proximal muscles 10 to 14 days and 3 to 6 weeks post injury in most distal muscles  Reduced MUP(motor unit potential) recruitment shown immediately after weakness from LMN injury  Presence of active motor units with voluntary effort and few fibrillations at rest good prognosis  Distinguishing preganglionic from postganglionic lesions
  • 56. NAP (nerve action potential )  SEP (somatosensory evoked potential)  CMAP (compound muscle action potential)
  • 57. Differentiates preganglionic from postganglionic injuries  If the injury proximal to the dorsal root ganglion (DRG), no Wallerian degeneration; a SNAP observed in a nerve with an anesthetic dermatome confirms a preganglionic lesion  SNAPs not useful for C5 evaluation, C5 does not provide a significant contribution to a major peripheral sensory nerve
  • 58. Intraoperative SSEPs are useful in brachial plexus surgery.  The presence of suggests continuity between the peripheral nervous system and the CNS via the DRG.  Absent in postganglionic or combined pre- and postganglionic lesions.
  • 59.
  • 60. A - acute exploration • concomitant vascular injury • open injury by sharp laceration • crush or contaminated wound  Open injury with low-velocity missile • Early exploration not indicated, unless injuries to adjacent vessels or viscera make immediate treatment necessary • Condition of the patient prevents extensive repair or grafting of the plexus • Injury inspected, its extent documented & observed
  • 61. A correct diagnosis of the amount of damage to the plexus established only by exploration.  Functional assessment of the nerve made by intra- operative nerve stimulation  A non-conducting neuroma resected and the gap reconstructed with nerve grafts
  • 62. B - early exploration (1- 2 weeks) • Unequivocal complete C5- T1 avulsion injuries • Facilities not available at initial exploration • Concomitant injuries requiring early care
  • 63. Complete injuries with no recovery by clinical examination or EMG at 12 weeks post injury  Distal recovery without regaining clinical or electrical evidence of proximal muscle function  Any return has ceased  Patient shows non-anatomical return of function with isolated lack of proximal function in the presence of good distal nerve recovery
  • 64. Evidence that the lesions at the postganglionic level  Anaesthetic limb, severe deafferentation pain, Horner’s syndrome and pseudomeningoceles on imaging  Postganglionic lesions :follow patients conservatively for up to 3 months to watch for spontaneous motor recovery. In upper-plexus injuries, if the biceps muscle not recovered within 3 months, then surgical exploration
  • 65.
  • 66. Stretch neurapraxia may regenerate healthy nerve tissue  Observation & physical therapy up to 8-10 weeks for spontaneous recovery  After 4 weeks a baseline electromyography and CT/MR myelography should be performed.
  • 67. Restoration of elbow flexion  Restoration of shoulder abduction  Restoration of sensation to the medial border of the forearm and hand
  • 68. Neurolysis  Nerve repair • Neurorrhaphy • End to side coaptation  Nerve graft  Nerve transfer or neurotization  Functional free muscle transfer  Carlstedt et al :reimplantation of avulsed roots
  • 69. Direct intraoperative nerve stimulation and recording required across damaged elements • If nerve action potentials are obtained, simple neurolysis indicated. • If neural integrity completely lost, or if no nerve action potentials recorded across a damaged element, excision and nerve grafting are required
  • 70. In root avulsions of the upper plexus in which no proximal neural stump is available for nerve grafting, neurotization between the intercostal nerves and the musculocutaneous nerve to restore elbow flexion
  • 71. Effective only if scar tissue seen around nerve or inside epineurium, preventing recovery or causing pain  Pre and post neurolysis direct nerve stimulation is mandatory to evaluate improvement in nerve conduction
  • 72. Sharp transection with excellent fascicular pattern and minimal scar  Lesions of the C5 and C6 nerve roots, the upper trunk, and the lateral cord proximal to the origin of the musculocutaneous nerve can be treated with some success
  • 73. Excellent in small nerves with one function  Viterbo :BR J Plast surg 1994  Denervated nerve brought with its cross section end to side with innervated nerve with creation of epineural/perineural windows
  • 74. Indicated for well defined nerve ends without segmental injuries  Intraoperatively a good fascicular pattern should be seen after the neuroma excision  Possible sources: sural, brachial cutaneous nerve, radial sensory and possibly ulnar nerve  Before implantation graft orientation reversed to minimize axonal branch loss  Surgical technique the most important factor in nerve graft
  • 75. A tension free nerve graft better than a primary repair under tension  Thin cutaneous grafts (e.g. sural nerve) prepared  Graft should be 20% longer than the length of the nerve defect  Endoscopic harvesting of the sural nerve graft devise to overcome the potential drawbacks of the open technique
  • 76. Mackinnon et all  Act as a temporary scaffold across which axons regenerate  Ultimately, the allograft tissue completely replaced with host material  Tacrolimus, greater potential and fewer side effects than other immunosuppressants, neuroregenerative and neuroprotective effects
  • 77. Nerve repairs performed with fibrin sealants produced less inflammatory response and fibrosis, better axonal regeneration, and better fiber alignment than the nerve repairs performed with microsutures alone  Fibrin sealant techniques were quicker and easier to use * J oint Reconstr Microsurg 2006
  • 78. Help in directing axonal sprouts from the proximal stump to the distal nerve stump  Provide a channel for diffusion of neurotropic and neurotrophic factors and minimize infiltration of fibrous tissue  Tubes made of biological materials such as collagen have been used with more success for distances of less than 3 cm  *PS Bhandari, LP Sadhotra, P Bhargava, AS Bath, MK Mukherjee, Pauline Babu Indian Journal of Neurotrauma (IJNT), Vol. 5, No. 1, 2008
  • 79. For repair of severe brachial plexus injury, in which the proximal spinal nerve roots have been avulsed from the spinal cord  Ideally performed before 6 months post injury but may be better suited than grafting in situation after the preferred 6 months time frame  A proximal healthy nerve coapted to the denervated nerve to reinnervate the latter by the donated axons
  • 80. The concept is to sacrifice the function of a lesser valued donor muscle to revive the function in the recipient nerve and muscle that will undergo reinnervation  Transferring a pure motor donor nerve to a motor recipient nerve gives the best result of motor neurotization, for example, spinal accessory to suprascapular neurotization
  • 81. Recipient site at the peripheral part of the plexus such as the musculocutaneous nerve, the suprascapular nerve, or the axillary nerve more effective than a recipient in the central part such as the posterior cord or the lower trunk  Reinnervate the recipient nerve as close to the target muscle as possible; ex. transfer of an ulnar nerve fascicle directly to the biceps branch of the musculocutaneous nerve in close proximity to its entry into the muscle Frederic et all
  • 82.
  • 83. Direct suture without tension always superior to indirect suture with a nerve graft  Especially true for the weak donor nerves such as intercostal nerves and the distal spinal accessory nerve  Ipsilateral nerve transfer always superior to the contralateral nerve transfer  Current trends in the management of brachial plexus injuries Indian Journal of Neurotrauma (IJNT), Vol. 5, No. 1, 2008
  • 84. A- intraplexal  B- extraplexal  Plexoplexal options are undamaged roots
  • 85. The transfer of a spinal nerve or more distal plexus component with intact spinal cord connections to a more important denervated nerve  Ruptured proximal nerve used  Examples include connecting the proximal stump of C5 or C6 to the distal aspect of C8, lower trunk, or median nerve, or the use of a portion of a functional ulnar nerve to the musculocutaneous nerve
  • 86. Transfer of a non brachial plexus component nerve to the brachial plexus  Sources commonly used include spinal accessory nerve, intercostal nerves, phrenic nerve, deep cervical motor branches, and contralateral C7 transfer
  • 87. Neuromuscular neurotization (direct implantation of motor nerve fascicles in to denervated muscle) from intraplexal sources
  • 88. Spinal accessory to surprascapular or musculocutaneous  Phrenic to axillary nerve  Intercostal to musculocutaneous long thoracic, radial and median nerve  Long head of triceps nerve to anterior branch of axillary nerve  Partial ulnar nerve transfer for elbow flexion  The contralateral C7 transfer preferred for hand flexors and sensation in global plexopathies
  • 89.
  • 90.
  • 91. Through a lateral fourth-rib thoracotomy the motor portion of the third, fourth, and fifth intercostal nerves transferred subcutane-ously into the axilla to be anastomosed to the musculocutaneous nerve
  • 92.
  • 93. If the interval from BPI to reconstruction delayed beyond 12 months, the results of surgical reconstruction with the intercostal nerves alone have been poor  Attributed to fibrosis of the motor end plates of the biceps muscle.  Under these circumstances, a free innervated gracilis muscle to replace the biceps
  • 94.
  • 95. Attachment is made proximally with the gracilis origin to the coracoid process and distally to the biceps tendon. After successful vascular anastomosis of the artery and vein, through an ipsilateral thoracotomy, intercostal motor nerves to the third, fourth, and fifth ribs are used to successfully reinnervate the gracilis
  • 96.
  • 97. For upper trunk injury with intact lower trunk: 1 to 2 fascicles of ulnar nerve anastomosed to biceps  Contra lateral C7 used in pan brachial plexopathy with multiple avulsions and limited donor possibility  Contra lateral C7 root extended by means of vascularised ulnar nerve graft in patient with C8 T1 avulsion and median nerve is the most frequent recipient  Another option is transferring nerve to long head of triceps to anterior branch of axillary nerve
  • 98. After brachial plexus repair and reconstruction, 12 to 18 months required to determine the extent of neural regeneration  If recovery considered inadequate, peripheral reconstruction considered
  • 99. The choice of the donor muscle-tendon unit or units not interfere with existing function  Adequate strength (a grade of at least 4 of 5) of the donor muscle must be confirmed  Avoid transferring a tendon when the muscle of that tendon was previously paralyzed and has now recovered.  The excursion of the donor muscle-tendon unit must be adequate
  • 100. Each tendon perform only one function  The transfer employs a straight line of pull  When possible, synergism should be employed such that the simultaneous contractions of different muscles combine to achieve a desired function  Manual or electrodiagnostic testing to check for inphase firing of planned donors with nearby, uninvolved motors should be performed preoperatively, to ensure that transferred motors and intact motors do not act as antagonists and prevent active motion
  • 101. Functional range of motion  Joint contractures released  The joint congruent and reduced  Skin supple without constricting scars  Trapezius-to-deltoid transfer as described by Saha to improve abduction and latissimus dorsi transfer to improve external rotation as described by L'Episcopo
  • 102. Deltoid and the clavicular head of the pectoralis major as prime movers for abduction; they also lift the humeral shaft  Subscapularis, supraspinatus and infraspinatus are a steering group which stabilise the humeral head in the glenoid.  The sternal head of pectoralis major, latissimus dorsi, teres major and teres minor form a depressor group which alsorotate the shaft and pull the humeral head downwards during the last few degrees of abduction.
  • 103. When any two of the steering group of muscles were paralysed a single muscle transfer to replace the deltoid would not provide abduction beyond 90°  Transfer of pectoralis minor, the upper two digitations of serratus anterior, latissimus dorsi and teres major in various combinations.  Transfers of the levator scapulae, sternocleidomastoid, scalenus anterior, scalenus medius and scalenus capitis
  • 104. Saha’s logical modification of the trapezius transfer described by Bateman  Provides a more distal fixation of the transfer after a more proximal release.  Greater lever arm, and fracture of the bony insertion transferred from the acromion allows better fixation to the narrow cylindrical shaft of the humerus.  An important modification to consider transfer for paralysed musclesof the rotator cuff, to improve control of the humeral head and prevent subluxation
  • 105. Adduction and internal rotation contracture :Release or recession of subscapularis muscle  Isolated abduction contracture: Release or recession of deltoid muscle  Abduction and external rotation contracture: Transfer of infraspinatus tendon to teres minor tendon;release or recession of infraspinatus and supraspinatus tendons with or without release of deltoid muscle
  • 106. Dysfunction of anterior and middle parts of deltoid muscle (partial reinnervation of paralyzed deltoid muscle) :Anterior transfer of posterior part of deltoid muscle  Dysfunction of supraspinatus or infraspinatus muscle :Transfer of latissimus dorsi tendon to greater tuberosity  Dysfunction of deltoid muscle Transfer of trapezius muscle with bone to lateral aspect of humerus; bipolar transfer of latissimus dorsi muscle
  • 107. Dysfunction of subscapularis muscle :Transfer of serratus anterior muscle; transfer of pectoralismajor tendon  Internal or external rotation deformity with incongruent glenohumeral joint :Humeral derotation osteotomy  Severe dysfunction of shoulder with pain or instability :Glenohumeral arthrodesis
  • 108. Reviewed 26 patients treated by trapezius transfer for deltoid paralysis due to brachial plexus injury or old poliomyelitis.  Assessed the power of shoulder abduction and the tendency for subluxation.  Good results in 16 patients (60%); five were fair and five poor.  Trapezius transfer appears to give reasonable results in the salvage of abductor paralysis of the shoulder.  J Bone Joint Surg [Br] 1998;80-B:114-6.
  • 109. Division of the clavicle and the acromion to allow transfer of the insertion of the central part of the trapezius
  • 110. The transfer unit is fixed to the humeral shaft with screws
  • 111. Radiograph after operation
  • 112. Active abduction before Active abduction after surgery. surgery.
  • 113. Failure due to persistent anterior subluxation after trapezius transfer
  • 114.
  • 115.
  • 116.
  • 117. Severe combined lesions and the surgeon cannot reasonably expect to achieve glenohumeral stability with any of the described soft-tissue procedures  To enhance the power of weak elbow flexion or extension transfers by isolating the forces of the transfer to the elbow
  • 118.
  • 119.
  • 120. Fusion in this attitude permits scapular motion, when combined with elbow motion, to allow the patient to reach all four major functional areas: face, midline, perineum, and rear trouser pocket
  • 121. Restoration of elbow flexion primary importance  Elbow flexion restored by intercostal neurotization or tendon transfer.  When the pectoralis major and latissimus dorsi areavailable for transfer, superior results anticipated
  • 122. Dysfunction of biceps muscle :Unipolar or bipolar transposition of pectoralis major muscle; bipolar transposition of latissimus dorsi muscle; free microvascular transfer of gracilis rectus muscle;modified Steindler flexorplasty; anterior transfer of triceps tendon  Dysfunction of triceps muscle :Transfer of latissimus dorsi muscle
  • 123. When the medial epicondylar muscles a weak or full extension of the elbow essential for transfer or ambulation, an alternative procedure considered  Steindler's procedure when the elbow flexors reach only grade 2, contrarily contraindicated when the elbow flexors are classified as grade 0, when the wrist flexors are weak, or when wrist and finger extensors are paralyzed
  • 124. proximal transfer (4 – 5 cm) and fixation of a piece of the medial epicondyle with its attached origin of the flexor-pronator muscle group in the middle of the anterior aspect of the humerus.
  • 125. Liu TK. Yang RS. Sun JS. Clinical Orthopaedics & Related Research. (296):104-8, 1993 Nov  Seventy-one consecutive patients treated with a modified Steindler flexorplasty from 1970 to 1987. Additional operative procedures included shoulder fusion (45 patients), tendon transfer (20 patients), and wrist tenodesis (3). Follow-up averaged 8.2 years. The outcome excellent in 32%, good in 47%, fair in 13%, and poor in 8%. Postoperatively, the mean arc of active elbow flexion 114 degrees; the average elbow extension loss, 28 degrees; the mean active pronation, 74 degrees; and supination, 30 degrees. Wire breakage found in two cases. Additional tendon transfer of flexor carpi ulnaris to extensor carpi radialis brevis improved the outcomes in the patients without active supination.  The modified Steindler flexorplasty provided predictable functional improvement in carefully selected patients with paralyzed upper extremities.
  • 126. An early but cosmetically unacceptable procedure : transfer of the sternocleidomastoid muscle which involves detaching this muscle from its insertion and linking it to the insertion of the biceps muscle by means of a long strip of fascia lata
  • 127. Extension Flexion
  • 128.
  • 129.
  • 130.
  • 131. Flexion Extension
  • 132.
  • 133. In hands in which the superficial flexors of the fingers and thenar muscles of opposition denervated, usually as the result of high median- nerve or brachial plexus injury, thumb opposition restored by transfer of the superficial flexor of the ring finger to the thumb through a dynamic pulley made from the distal segment of flexor carpi ulnaris which is attached to the extensor carpi ulnaris, combined with transfer of the proximal segment of flexor carpi ulnaris to the transferred paralyzed superficial ring-finger flexor tendon
  • 134. C5-6 type :  complete loss of voluntary shoulder and elbow control, although many can still extend the wrist by using finger extensors and the extensor carpi ulnaris. Thumb and index finger sensation impaired  Figure-of-8 harness and Bowden cable a used to provide body-powered elbow flexion, sometimes with an elbow hinge that can be locked in several positions; Shoulder subluxation also reduced by su
  • 135.
  • 136. C5-7 type  adds radial palsy to the above picture, sensory loss in the hand increase, but all active extension at the wrist, hand, and fingers lost  Possible to add either static or spring-assisted wrist, hand, and finger extension to the previous orthosis.
  • 137.
  • 138. c7- 8 Tl type  Good shoulder and elbow function but loses finger flexors, extensors, and intrinsics  Surgical reconstruction often of particular value  Those who sustain a concomitant traumatic transradial amputation : body-powered or switch- controlled terminal device
  • 139. C8, Tl type  Enjoys the greatest percentage of orthotic success since motor rather than sensory loss significant  Although finger flexors and intrinsics are paralyzed, sensory loss is limited to the ring and small digits, which are not involved in pinch prehension
  • 140.
  • 141.
  • 142.
  • 143. In view of the substantial percentage of BPI amputees who reject prosthetic devices, it has been argued that orthotic restoration is an equally plausible alternative. Wynn Parry has reported his experience with a series of over 200 cases and states that 70% continue to use a full-arm orthosis for work or hobby activities after 1 year  Wynn Parry CB: Rehabilitation of patients following traction lesions of the brachial plexus. Clin Plast Surg 1984
  • 144.
  • 145.
  • 146. A thorough physical examination including manual and EMG muscle testing required to assess rehabilitation potential.  The patient actively involved in all prescription decisions from the outset; without a motivated and cooperative individual, even heroic prosthetic/orthotic interventions are doomed to failure.  Full-arm orthosis during the recovery period, beginning as soon as the patient has come to terms with the serious and potentially permanent nature of his injuries.  Once surgical reconstruction and spontaneous recovery are complete, amputation and trial with a prosthesis can be considered.  Psychological and social work consultation may be useful to help the patient discuss the altered body image and employment possibilities that will follow amputation.
  • 147. Most of these injuries resolve without operative intervention  Joint mobilization and range-of-motion exercises performed by the parents and guided by a physical or occupational therapist can help to maintain a congruent glenohumeral joint and to minimize contractures  For severely affected, however, a variety of procedures are available
  • 148. 3-9 mnths : Exploration and repair of brachial plexus  12-24 nths : Release of contractures  24-60 mnths : Tendon and muscle transfers  >60 (and incongruent joint) :Osseous procedures
  • 149. As long as the glenohumeral joint is congruent, tendon and muscle transfers may be performed at a later date, but they should be considered at these earlier times to maximize functional recovery  Joint incongruity increase with the patient’s age  Patients with incomplete recovery who are seen more than six months after birth frequently have muscle contractures due to unopposed muscle forces and are no longer candidates for direct repair of the plexus
  • 150. Performed in patients first seen when they are older than five years of age  Humeral rotational osteotomy for persistent internal rotation contracture and glenohumeral arthrodesis in the setting of severe pain, instability, or arthritic changes  For posterior dislocation of the humeral head :posterior capsular plication
  • 151. Highly dependent on pattern of injury  Complete C4 to T1 injuries a considered most severe and virtually irreparable  Avulsion injuries from C5 toT1 amenable to restoration of shoulder and elbow function only  Ideal candidate for surgery are patients with proximal rupture or avulsion and sparing of lower trunk
  • 152. Since 1995 to 2002 , 505 patients studied for functional and occupational outcome after surgery for BPI  In India BPI most common due to RTA with Rt side involved in 2/3  40% cases have pan BPI  85% of cable graft yielded improvement in motor power compared 68% in neurotized nerve and 66% in patients undergoing neurolysis
  • 153. Most effective donor nerve for musculocutaneous neurotization was medial pectoral nerve (63.6%) patient improved  Accessory nerve was most effective for neurotization of suprascapular nerve (100%)  Thoracodorsal axillary neurotization gave (66.7% improvement)  50% patients either remained unemployed or had to change there jobs
  • 154. Sedel reported results of surgical treatment of 63 traumatic brachial plexus palsies, 32 complete and 31 partial.  Of the 32 complete palsies, 26 had repair procedures; 21 were improved.  Of the 31 partial palsies, 23 had repair procedures, and 20 were improved.  Results of nerve transfer were disappointing
  • 155. Solonen et al. reviewed 52 brachial plexus injuries treated surgically :Grafts used in 24 avulsions, neurolyses in 14, direct suture in 2, and intercostal neurotization in 12.  Good results seen in 19 patients after fascicular grafting with return of function of the biceps muscle.  Neurotization produced function in 4 of 12 patients.
  • 156. Narakas reported surgical treatment by repair, grafting, or neurolysis in 164 patients with traction injuries and found that 85% of 20 patients with infraclavicular injuries improved after surgery, and that only 55% of 58 patients with supraclavicular injuries improved
  • 157. Barnes found that 13 patients with plexus injuries but without EMG evidence of degenerative changes at 3 weeks recovered rapidly and completely.  Of 33 patients with upper plexus injuries, 22 spontaneously regained significant function of the muscles of the shoulder, elbow, and wrist. Of 26 with lower plexus injuries, 18 regained some proximal muscle function.
  • 158. In 1977, Millesi, using the interfascicular autogenous nerve grafting technique, reported return of M3 or better power (Highet) in 38 (70%) of 54 patients  In 1984, Millesi :134 patients with complete brachial plexus lesions treated with neurolysis, nerve grafting, and neurotization. Useful function was regained in 47 of 65 patients (72%) after nerve grafting. In 72 patients with injury to the upper plexus only, useful function returned in 21 of 28 patients (75%) after nerve grafting