1. UV BLOCK GEL
(

2. (UV
BLOCK GEL)
Active Type of UV Maximum Use in
ingredient radiation Concentrati This sun
blocked on blocked
Ethylhexyl- UV-B 7.5% (US), 5.00%
p- 10% (TH,
methoxyci EC, AUS)
nnamate
Butyl UV-A % (US), 5.00%
methoxydi % (TH,
benzoyl EC,AUS)
methane
Oxybenzon UV-A,-UV-B 6% baicalensis 2.00%
Scutellaria (US), root

3. The depth of penetration of the skin by UV radiation of
different wavelengths: UVB mainly affects the epidermis,
while UVA penetrates deeper into the dermis.
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4. Penetration of UV radiation into
skin
dermatology.ucsf.edu

5. (Metal Halide Lamp)

7. (Chemical
Sunscreen)
- Ethylhexyl-p-
methoxycinnamate
- Butyl
methoxydibenzoyl methane
- Oxybenzone

8. (Chemical Sunscreen)

9. Ethylhexyl-p-methoxycinnamate
 Ethylhexyl-p-
methoxycinnamate
SPF
Solvent
 Wavelengths Covered
: - nm.

10. Butyl Methoxydibenzoylmethane
Butyl
Methoxydibenzoylmet
hane Avobenzone
Chemical
UVA
Wavelengths
Covered : - nm

11. Oxybenzone
 Benzophenone-
Oxybenzone
 Skin Cancer
Foundation
Oxybenzone
Stabilizer
Avobenzone
Neutrogena
Helioplex
Avobenzone
Oxybenzone
Oxybenzone
Degrade

12. Scutellaria Bai
calensis
Root Extract

13. Benefits
1. Anti inflammations
2. Help leukocyte migration and activation
3. Help free radical scavenging
4. The prevention of lipid peroxidation
5. Depigment Agent

16. Physiology of Inflammation
S.baicalensis flavonoids are effective at the level of enzymes in
arachidonic acid metabolism,as well as in leukocyte migration and
activation, free radical scavenging, and the prevention of lipid
peroxidation.
Anti-inflammatory Mechanisms of Scutellaria
A major inflammation-modulating action of S. baicalensis GEORGI is via
its effects on lipoxygenase in arachidonic acid metabolism. Arachidonic
acid, which is esterified in membrane phospholipids,is released in the initial
stages of inflammation,generally in response to mediators from activated
platelets.Platelets themselves are activated by contact with substances
relating to the initial injury such as collagen, thrombin,and bradykinin.

18. Depigment Agent
• Inhibitory effects on L-DOPA oxidizing
diphenolase activity of tyrosinase.
• Chelation with copper ion.
• Inhibition of melanin biosynthesis in
cells by their potent antioxidant
activities.

21. Among the tested hydroxyflavones -

22. Results suggested that the mechanism o
f inhibition by could
be due to its chelation with copper ion i

23. Results indicate that the , , -trihydro
xyflavones may contribute to
the inhibition of melanin biosynthesis i

24. Conclusion
Scutellaria baicalensis is high in
active flavonoids.
1.Anti – Inflammatory
2.Depigment Agent
* Inhibitory effects on L-DOPA ox
idizing diphenolase activity
of tyrosinase.
Chelation with copper ion.
Inhibition of melanin biosynthe
sis in cells by their potent antioxi
dant activities.

25. Summary Properties of the UV BLOCK GEL
1.
Scutellaria baicalensis