plegable de biologia molecular

1. BACTERIAL PROTEIN ACETYLATION AND ADAPTATION VIA SYMBIOSIS María Fernanda Marín Betancourt UPB Faculty of Medicine 3th semester 2010

2. Folding

3. Folding

5. In bacterias this was specific to histones, the proteins which involves the DNA.

7. Bacterialprotein acetylation: thedawning of a new age. The histone acetylation is the main acetylation reaction in bacterias. Protein acetylation works like a control key in internal cellular control (in eukaryotes).

8. Bacterialprotein acetylation: thedawning of a new age. Recently, researchers have found acetylated proteins in the mitochondrion of E.coli and S. enterica. This discover make us think that bacterias could have any kind of cellular control mechanism mediated by protein acetylation.

9. Estudentopinion. I think that the discover of this primary eukaryotic mechanism in bacterias, gives to the researchers a new point of view about how the bacterias control their process, in contrast with eukaryotic cells.

10. Adaptation via symbiosis. The fruit fly, is the example to show how this symbiotic interaction works. The fly enemy is a nematode that infects it and makes it sterile. The bacteria called spiroplasma defends the bacteria from its enemy the nematode.

11. Adaptation via symbiosis. The bacteria, who benefits the fly, can be inherited to the offspring of the fly. The symbiotic association between this two organisms shows that there’s no need to be the strongest organism, when you can have a friend to help you.

12. Studentopinion. I think this kind symbiotic relation between a bacteria and an organism would be an excellent way to protect us against diseases we cannot defend ourselves but bacterias can.

13. Medical Utility

14. Bacterialprotein acetylation: thedawning of a new age. This discovery could let us to create new antibiotics to control infections. And this will helps us to increase our knowledge about how bacterias control inside.

15. Adaptation via symbiosis. This new kind of symbiotic relationship, could be very important to prevent o to treat diseases with the help of a tiny microorganisms like a bacteria. The possibility to inherit the microorganism could be an excellent way to prevent diseases in the future, our children could be more healthy.

16. Bibliography John Jeanike, Robert Unckless, et al. Adaptation via Symbiosis: recent spread of a drosophila defensive symbiont. Science 9 July 2010: Vol. 329 nº 5988, pp. 212-215 DOI:10.1126/science. 1188235. HuLinda, Lima Bruno P, Wolfe Alan; Bacterial protein acetylation: The dawning of a new age. Molecular Microbiology; (2010) 77(1), 15-22

17. Thanks