Seminar on suspended animation

1. Mahesh Patil
M130379me

2.  What is suspended animation?
It is the slowing of life processes by external
means without termination.

3. Scope of presentation
 Introduction
 History
 Suspended animation Cryonics
 Related terms and concepts
 How it is done?
 Recent developments
 Obstacles
 future scope

5.  Suspended : Caused to stop for a while
 Animation : to give movement ; to give life
De-animate
Suspend
Re-animate

6. Some interesting terms
 Cryonics
 Cryopreservation ( Cryoconservation )
 Cryoprotectants (anti-freeze agent)
 Definition of death legally dead!
 Hibernation
 Vitrification Glass transition temperature
 Induced hypothermia
 Role of H2S and comparison with H2O

7. Cryonics
 Low temperature preservation
 hope of future healing and cure
 First proposed in 1962
 270 people have gone under cryopreservation
 Stopping of enzymatic or chemical activity
 Coating the material to be frozen with cryoprotectants

8.  Information-theoretic death Vs clinical death
destruction of the information within a human brain
to such an extent that recovery of the original person
is theoretically impossible by any physical means
 Hypothermia: metabolic rate maintainace.

9. Vitrification
 Amorphous substances
 Transformation of substance into glass
 Glass transition temperature
 Removal of water
 Sharp edge action

10. Need of vitrification
 Removal of water
 Injecting cryoprotectants ( gycerol based)
 Sharp edge action
 Volume expansion of during solidification

11. How it is done?!!
 Join any cryonics facility Be a member
 When your heart stops pronounced legally dead!
 Emergency response team
 Body in packed with ice
 Injection of heparin (anticoagulant): to prevent
clotting
 Transport Vitrification (Cryoprotectant)
 Cooled using dry ice ( till -130 Celsius )
 Immersion in liquid Nitrogen ( -196 Celsius )

12.  Preservation
tank

13. Recent developments
 Role of H2S
binds to cytochrome oxidase ( mitochondria )
stops oxygen to bind
slowdown of metabolism
hibernation
 How hibernation is related?
 Example of power and lamp

14.  Experiment in 2005 on mice:
 low dosage of H2S ( 81 ppm )
 breathing rate : 120 beats/min 10 beats/min
body temperature: 37 °C to 2 °C above ambient
cold blooded (poikilotherm)

15.  Future scope
 Benefits: medical, space and many more

16. Referances
 Contributions of Mark Roth ( University of
Washington )
 Alcor Life Extension Foundation: Cryonics
 Advances in human cryopreservation, 2007, Florida
 Internet