SlideShare a Scribd company logo
1 of 43
Download to read offline
KERALA UNIVERSITY OF HEALTH SCIENCES
Thrissur 680596
SYLLABUS
UNDRE GRADUATE COURSE IN
PERFUSION TECHNOLOGY
Course Code 015
2016-17 admission onwards
(Approved by the Academic Council)
SYLLABUS2016
1
(This is excerpted from the draft Regulations document being prepared by the KUHS.
Hence the numbering pattern is being retained)
2. COURSE CONTENT
2.1 Title of the course
Bachelor of Science in Perfusion Technology
(BSc. Perfusion technology)
2.2 Objectives of the Course-
Perfusion Technology degree course is to provide a competent Cardiac Perfusionist who
is well versed with modern technologies and up to date knowledge in patient care.
A perfusionist, also known as a clinical perfusionist or a cardiovascular perfusionist,
is a specialized healthcare professional who uses the heart-lung machine during cardiac
surgery and other surgeries that require cardiopulmonary bypass to manage the
patient's physiological status.The perfusionist is a highly trained member of the
cardiothoracic surgical team which consists of cardiac surgeons, anesthesiologists,
physician assistants, surgical technologists, and nurses. The perfusionist is solely
responsible for the management of the physiological and metabolic needs of the
cardiac surgical patient so that the cardiac surgeon may operate on a still, unbeating
heart. This is accomplished through the utilization of the heart-lung machine,
oxygenator, filters, reservoirs and tubing. The perfusionist is responsible for the
management of circulatory and respiratory functions of the patient so that the cardiac
surgeon can focus on the actual surgical procedure. Other responsibilities include
autologous blood collection and processing, implementation and management of the
intra-aortic balloon pump, adult and infant extracorporeal membrane oxygenation
(ECMO), monitoring of anticoagulation, electrolyte, acid-base balance and blood-gas
composition,placing and managing patients on ventricular assist devices as bridge to
2
recovery or heart transplantation and supporting patients receiving lung or liver
transplants and in procurement of cardiothoracic donor organs for transplantation
Cardiovascular Perfusion Technology involves the study of physiology,
pathology and associated equipment used to support and/or assume the function of
the heart and/or lungs during medical procedures. The perfusion technologist prepares
and operates the heart-lung machine and other sophisticated equipment as directed
by healthcare physicians. The perfusionist measures various blood and other
parameters to identify appropriate mechanical, pharmacological and thermal
manipulation to maintain tissue viability. To perform these tasks the perfusionist must
have a thorough understanding of the both respiratory and circulatory systems and be
able to operate complex equipment. Additionally the perfusionist must be capable of
handling stressful situations, pay great attention to detail, communicate effectively,
and be willing to stay abreast of new developments in the profession
This course is to provide a framework to guide safe and effective
cardiopulmonary bypass (CPB). Clinical teams implement the content of this document
when developing institution-specific protocols for patients undergoing cardiac surgery
utilizing CPB.
A Perfusionist shall conduct cardiopulmonary bypass in compliance with
departmental protocols. A patient-specific management plan for the
cardiopulmonary bypass (CPB) procedure shall be prepared and communicated to
the surgical team either during the pre- operative briefing or prior to beginning the
procedure.The perfusionist should participate in the post-procedure debrief with the
surgical team.
The mission of the KUHS is to encourage and foster the development of the
profession of clinical perfusion through education and certification, so as to provide
optimum patient care. A perfusionist shall recognize that the term “professional
ethics” incorporates a commitment to service, to competent practice and to
consistent development for the benefit of the community. This code shall guide the
conduct of the perfusionist in all circumstances. Perfusionist who has successfully
completed an accredited educational program and has successfully taken the
3
examinations set by KUHS and BSc Perfusion Technology Degree will be awarded to
them.
The goals of the Degree are diverse and include: -development of
professional standards for perfusion - enhancement of perfusion scope of practice -
development of continuing education programs on national and regional levels -
support of educational programs for entering perfusionists - scientific dissemination
of knowledge
2.3 Medium of Instruction
The medium of instruction for the course shall be English.
2.4 Course outline
As given in curriculum
2.5 Duration
Duration shall be for a period of four years including one year internship training.
2.6 Subjects
As given curriculum
2.7 Total number of hours
The number of hours of teaching theory and practical subject wise in first year, second
year and third year are shown in Table-I, Table-II and Table-III
Table - I Distribution of Teaching Hours in First Year Subjects
4
Main Subjects
SL
NO
Subject Theory
No Of Hrs
Practical No
Of Hrs
Total No.
of Hours
1
Human Anatomy 70
20 90
2 Physiology 70 20
90
3
Biochemistry
70 20
90
4
Pathology-[Clinical pathology,
Haemotology &
Blood –Banking] 70 20
90
5
Microbiology
70 20
90
Total 350 100 450
The classes in main subjects are to be held from Monday to Thursday. On Fridays and
Saturdays students shall work in hospitals in the respective specialty or department chosen
by them
Clinical/Lab posting -470Hours- Fri day 9am - 1pm and 2pm - 4-30 pm
Saturday 9am - 1pm
Table - II Distribution of Teaching Hours in Second Year Subjects
Main Subjects-No of hrs
SL
NO Subject
Theory Practical Clinical
Posting
Total Hours
1 Medicine relevant to
perfusion
technology
50 -
-
-
-
50
5
2 Section A
Applied Pathology
30 30 -
-
60
3 Section B
Applied Microbiology
30 30 60
4 Applied Pharmacology 50 -
-
50
5
Introduction to Perfusion
Technology 80 100 65
0
830
Total 240 160 65
0
1050
Table -III Distribution of Teaching Hours in Third Year Subjects
Main Subjects-No of hrs
S L
No Subje
ct
Theory Practical Clinical
posting
Tota
l
Hour
s
1 Perfusion
Technology – Clinical
50 50 25
0
350
2
Perfusion
Technology – Applied 50 50 25
0
350
3
Perfusion
Technology –
Advanced
50 50 25
0
350
Total 15
0
15
0
75
0
105
0
2.8 Branches if any with definition
Not applicable
2.9 Teaching Learning methods
 Lecture and practical classes
 During the internship year the candidates should do 5 months of internship is
in an external institute (approved by KUHS) and the remaining 5 months in
the parent institute.
6
2.10 Content of each subject in each year
ANATOMY
No. of theory classes: 70 hours
No. of practical classes: 20 hours
1.Introduction: human body as a whole
Theory:
Definition of anatomy and its divisions
Terms of location, positions and planes
Cell and its organelles
Epithelium-definition, classification, describe with examples, function
Glands- classification, describe serous & mucous glands with examples
Basic tissues - classification with examples
Practical: Histology of types of epithelium
Histology of serous, mucous & mixed salivary gland
2.Locomotion and support
Theory:
Cartilage - types with example & histology
Bone - Classification, names of bone cells, parts of long bone, microscopy of compact bone,
Names of all bones, vertebral column, intervertebral disc, fontanelles of fetal skull
Joints - Classification of joints with examples, synovial joint (in detail for radiology)
Muscular system: Classification of muscular tissue & histology
Names of muscles of the body
Practical: Histology of the 3 types of cartilage
Demo of all bones showing parts, radiographs of normal bones & joints
Histology of compact bone (TS & LS)
Demonstration of all muscles of the body
Histology of skeletal (TS & LS), smooth & cardiac muscle
7
3. Cardiovascular system
Theory:
Heart-size, location, chambers, exterior & interior
Blood supply of heart
Systemic & pulmonary circulation
Branches of aorta, common carotid artery, subclavian artery, axillary artery, brachial artery,
Superficial palmar arch, femoral artery, internal iliac artery
Peripheral pulse
Inferior venacava, portal vein, portosystemic anastomosis
Great saphenous vein
Dural venous sinuses
Lymphatic system- cisterna chyli & thoracic duct
Histology of lymphatic tissues
Names of regional lymphatics, axillary and inguinal lymph nodes in brief
Practical: Demonstration of heart and vessels in the body
12 Histology of large artery, medium sized artery & vein, large vein
Microscopic appearance of large artery, medium sized artery & vein,
Large vein pericardium
Histology of lymph node, spleen, tonsil & thymus
Normal chest radiograph showing heart shadows
Normal angiograms
4. Gastro-intestinal system
Theory:
Parts of GIT, Oral cavity (lip, tongue (with histology), tonsil, dentition, pharynx, salivary
glands, Waldeyer's ring)
Oesophagus, stomach, small and large intestine, liver, gall bladder, pancreas
Radiographs of abdomen
5. Respiratory system
Parts of RS, nose, nasal cavity, larynx, trachea, lungs, bronchopulmonary segments
Histology of trachea, lung and pleura
Names of paranasal air sinuses
8
Practical: Demonstration of parts of respiratory system.
Normal radiographs of chest
Histology of lung and trachea
6. Peritoneum
Theory: Description in brief
Practical: Demonstration of reflections
7. Urinary system
Kidney, ureter, urinary bladder, male and female urethra
Histology of kidney, ureter and urinary bladder
Practical: Demonstration of parts of urinary system
Histology of kidney, ureter, urinary bladder
Radiographs of abdomen-IVP, retrograde cystogram
8. Reproductive system
Theory:
Parts of male reproductive system, testis, vas deferens, epididymis, prostate (gross &
histology) Parts of female reproductive system, uterus, fallopian tubes, ovary (gross &
histology) Mammary gland - gross
Practical: Demonstration of section of male and female pelves with organs in situ
Histology of testis, vas deferens, epididymis, prostate, uterus,
Fallopian tubes, ovary
Radiographs of pelvis - hysterosalpingogram
9. Endocrine glands
Theory:
Names of all endocrine glands in detail on pituitary gland, thyroid gland, parathyroid
gland,
Suprarenal gland - (gross & histology)
Practical: Demonstration of the glands
13 Histology of pituitary, thyroid, parathyroid, suprarenal glands
10. Nervous system
Theory:
Neurons, Classification of NS
9
Cerebrum, cerebellum, midbrain, pons, medulla oblongata, spinal cord with spinal nerve
(gross &histology) Meninges, Ventricles & cerebrospinal fluid, Names of basal nuclei,
Blood supply of brain, Cranial nerves.Sympathetic trunk & names of parasympathetic
ganglia
Practical: Histology of peripheral nerve & optic nerve
Demonstration of all plexuses and nerves in the body
Demonstration of all part of brain
Histology of cerebrum, cerebellum, spinal cord
11. Sensory organs:
Theory:
Skin: Skin-histology, Appendages of skin
Eye: parts of eye & lacrimal apparatus, Extra-ocular muscles & nerve supply
Ear: parts of ear- external, middle and inner ear and contents
Practical: Histology of thin and thick skin
Demonstration and histology of eyeball
Histology of cornea & retina
12. Embryology
Theory:
Spermatogenesis & oogenesis
Ovulation, fertilization
Fetal circulation
Placenta
Theory
Type of Questions No. of Marks
10
Questions Sub-total
Long Essay (LE) 2 2 x 10 20
Short Essay (SE) 6 6 x 5 30
Short Answer (SA)
10 10 x 3 30
Total Marks
80
There shall be one theory paper of three hours duration carrying 80 marks. Distribution of
type of questions and marks for Anatomy shall be as given under
NO PRACTICAL EXAMINATION
REFERENCE BOOKS
Anatomy
1. William Davis (P) understanding HumanAnatomy and Physiology MC Graw Hill
2. Chaursia -A Text book of Anatomy
T.S. Ranganathan - A text book of Human Anatomy
3. Fattana, Human anatomy (Description and applied) Saunder’s & C P Prism Publishers,
Bangalore - 1991
4. ESTER. M. Grishcimer, Physiology & Anatomy with PracticalConsiderations, J.P. Lippin
Cott. Philadelphia
5. Essential of Human embryology, Bhatnagar revised edition, Orient Longman PVT Ltd.
11
PHYSIOLOGY
Theory 70 hours
Practical 20hours
1.Introduction - composition and function of blood
Red blood cells - Erythropoiesis, stages of differentiation function, count physiological
Variation.
Haemoglobin -structure, functions, concentration physiological variation
Methods of Estimation of Hb
White blood cells - Production, function, life span, count, differential count
Platelets - Origin, normal count, morphology functions.
Plasma Proteins - Production, concentration, types, albumin, globulin, Fibrinogen,
Prothrombin, Functions.
Haemostasis & Blood coagulation
Haemostasis - Definition, normal haemostasis, clotting factors, mechanism of clotting,
disordersof clotting factors.
2.Blood Bank
Blood groups - ABO system, Rh system, Blood grouping & typing, Crossmatching
Rh system - Rh factor, Rh in compatibility.
Blood transfusion - Indication, universal donor and recipient concept, Selection criteria of a
blood donor. Transfusion reactions Anticoagulants - Classification, examples and uses
3.Anaemias: Classification - morphological and etilogical. Effects of anemia on body
Blood indices - Colour index, MCH, MCV, MCHC
Erythrocyte sedementation Rate (ESR) and Paced cell volume, Normal values, Definition.
Determination,
4.Blood Volume -Normal value, determination of blood volume and its regulation
Body fluid - pH, normal value, regulation and variation
Lymph - lymphoid tissue formation, circulation, composition and function of lymph
12
5.Cardiovascular system
Heart - Physiological Anatomy, Nerve supply
Properties of Cardiac muscle, Cardiac cycle-systole, diastole. Intraventricular pressure
curves.Cardiac Output - only definition
Heart sounds- Normal heart sounds Areas of auscultation.
Blood Pressure - Definition, normal value, clinical measurement of blood pressure.
Physiological variations, regulation of heart rate, cardiac shock, hypotension, hypertension.
Pulse - Jugalar, radial pulse, Triple response
Heart sounds - Normal heart sounds, cause characteristics and signification. Heart rate
Electrocardiogram - (ECG) -significance.
6.Digestive System - Physiological anatomy of Gastro intestinal tractand its functions
Salivary glands-Stucture and functions. Deglutination -stages and regulation
Stomach - structure and fuctions
Gastric secretion - Composition function regulation of gastric juice secretion
Pancrease - structure, function, composition, regulation of pancreatic juice
7.Liver - functions of liver, Bile secretion, composition, function regulation of bile secretion
.Bilirubin metabolism types of bilirubin, Vandernberg reaction, Jaundice- types, and
significance.
Gall bladder - functions
Intestine - small intestine and large intestine
Small intestine -Functions- Digestive, absorption, movements.
Large intestine - Functions, Digestion and absorption of Carbohydrates, Proteins, Fats,
Lipids.Defecation
8.Respiratory system-Functions of Respiratory system, Physiological Anatomy of
Respiratory system, Respiratory tract,Respiratory Muscles, Respiratory organ-lungs, Alveoli,
Respiratory membrane, stages of respiration.Mechanism of normal and rigorous respiration.
Forces opposing and favouring expansion of thelungs. Intra pulmonary pleural pressure,
surface tension, recoil tendency of the wall. Transportation of Respiratory gases:
Transportation of Oxygen: Direction, pressure gradient, Forms of transportation,
Oxygenation of Hb. Quantity of Oxygen transported.
9.Lung volumes and capacities
13
Regulation of respiration what? Why? How? Mechanisms of Regulation, nervous and
chemical regulation. Respiratory centre. Hearing Bruer Reflexes.
Applied Physiology and Respiration: Hypoxia, Cyanosis, Asphyxia, Dyspnea, Dysbarism,
Artificial Respiration, Apnoea.
10.Endocrine System - Definition Classification of Endocrine glands & their Harmones
Properties of Harmones.
Thyroid gland hormone - Physiological, Anatomy, Hormone scerated, Physiological function,
regulation of secretion. Disorders - hypo and hyper secretion of hormone
Adrenal gland, Adrenal cortex physiologic anatomy of adrenal gland, Adrenal cortex, cortical
hormones - functions and regulation
Adrenal medulla - Hormones, regulation and secretion.
Functions of Adrenaline and nor adrenaline
Pituitary hormones - Anterior and posterior pituitary hormones, secretion, function
Pancreas - Hormones of pancreas
Insulin - secretion, regulation, function and action
Diabetes mellitus - Regulation of blood glucose level
Parathyroid gland - function, action, regulation of secretion of parathyroid hormone.
Calcitonin - function and action
11.Special senses
Vision - structure of eye. Function of different parts.Structure of retina
Hearing structure and function of can mechanism of hearing
Taste - Taste buds functions. Smell physiology, Receptors.
12. Nervous system
Functions of Nervous system, Neurone structure, classification and properties. Neuroglia,
nerve fiber, classification, conduction of impulses continuous and saltatory. Velocity of
impulse transmission and factors affecting. Synapse - structure, types, properties.
Receptors - Definition, classification, properties. Reflex action - unconditioned properties of
reflex action. Babinski's sign. Spinal cord nerve tracts. Ascending tracts, Descending tracts -
pyramidal tracts - Extrapyramidal tracts. Functions of Medulla, pons, hypothalamic
disorders.
Cerebral cortex lobes and functions, Sensory cortex, Motor cortex, Cerebellum functions of
14
Cerebellum.Basal ganglion-funtions. EEG.
Cerebro Spinal Fluid (CSF): formation, circulation, properties, composition and functions
lumbar puncture.
Autonomic Nervous System: Sympathetic and parasympathetic distribution and functions
and comparison of functions.
13 Excretory System, Excretory organs
Kidneys: Functions of kidneys structural and functional unit nepron, vasarecta, cortical and
Juxtamedullary nephrons - Comparision, Juxta Glomerular Apparatus -Structure and
function. Renal circulation peculiarities.
Mechanism of Urine formation: Ultrafiltration criteria for filtration GFR, Plasma fraction,
EFP, factors effecting EFR. Determination of GFR selective reabsorption - sites of
reabsorptionsubstance reabsorbed, mechanisms of reabsorption Glucose, and urea.
H + Cl aminoacids etc. TMG, Tubular lead, renal threshold % of reabsorption of different
Substances, selective e secretion.
Properties and composition of normal urine, urine output. Abnormal constituents in urine,
Mechanism of urine concentration.Counter - Current Mechanisms: Micturition, Innervation
of Bladder, Cysteurethrogram.
Diuretics: Water, Diuretics, osmotic diuretics, artificial kidney renal function tests – plasma
clearance Actions of ADH, Aldosterone and PTH on kidneys. Renal function tests
14 Reproductive system
Function of Reproductive system, Puberty, male reproductive system. Functions of testes,
Spermatogenesis site, stages, factors influencing semen. Endocrine functions of testes
Androgens - Testosterone structure and functions. Female reproducive syustem. Ovulation,
Menstrual cycle. Physiological changes during pregnancy, pregnancy test. Lactation:
Composition of milk factors controlling lactation.
15 Muscle nerve physiology
Classification of muscle, structure of skeletal muscle, Sarcomere contractile proteins,
Neuromuscular junction. Transmission across, neuromuscular junction. Excitation
contractioncoupling. Mechanism of muscle contraction muscle tone, fatigue Rigour mortis
16 Skin -structure and function
15
Body temperature measurement, Physiological variation, Regulation of body Temperature
by physical chemical and nervous mechanisms .Role of Hypothalamus, Hypothermia and
fever.
Practicals
Haemoglobinometry
White Blood Cell count
Red Blood Cell count
Determination of Blood Groups
Leishman's staining and Differential WBC count
Determination of packed cell Volume
Erythrocyte sedimentation rate [ESR]
Calculation of Blood indices
Determination of Clotting Time, Bleeding Time
Blood pressure Recording
Auscultation for Heart Sounds
Artificial Respiration
Determination of vital capacity
Internal Assessment
Theory - Average of two exams conducted. 20
Practicals: Record & Lab work* 10
* There shall be no University Practical Examination and internal assessment marks secured
in Practicals need not be sent to the University.
Theory
There shall be one theory paper of three hours duration carrying 80 marks. Distribution of
type of questions and marks for Physiology shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
16
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 6 6 x 5 30
SHORT ANSWER (SA) 10 10 x 3 30
TOTAL MARKS 80
NO PRACTICAL EXAMINATION
REFERENCE BOOKS
Physiology
1. Guyton (Arthur) Text Book of Physiology.
Latest Ed. Prism publishers
2. Chatterjee (CC) Human Physiology Latest Ed.
Vol-1, Medical Allied Agency
3. Choudhari (Sujith K) Concise Medical Physiology Latest Ed. New Central Book,
4. Ganong
BIOCHEMISTRY
1. Carbohydrates
-Classification and reactions of carbohydrates
-Metabolism of carbohydrate
-Glycolysis, Gluconeogenesis,
-Significance of HMP shunt pathway,
-Glycogen metabolism, regulation of blood glucose
-Diabetes mellitus –classification, metabolic derangement, complication and monitori
2. Lipids
-Classification of lipids, Biomembrane, importance of PUFA
-Metabolism of lipids
-Oxidation of fatty acids, synthesis of fatty acids, cholesterol, lipoproteins, dyslipidemias
3. Proteins.
-Structure of protein with examples, Classification of amino acids
17
-Compounds formed from amino acids,
-inborn errors of metabolism of amino acids
4. Enzymes.
-Classification, Kinetics, enzyme inhibition, regulation of enzyme action, clinical enzymology
5. Acid base balance.
-Regulation of normal blood pH, derangements in acid base status, compensatory
mechanisms, anion-gap, arterial blood gas analysis.
6. Water and Electrolyte balance
7. Hemoglobin.Synthesis of heme, porphyria, degradation of heme, Jaundice.
8. LFT, RFT
9. Vitamins.-Fat soluble vitamins, water soluble vitamins
10. Minerals.Calcium and Iron in detail, selenium, copper, zinc, Phosphorus
PRACTICALS
1. Analysis of Normal Urine
2. Composition of urine
3. Procedure for routine screening
4. Urinary screening for inborn errors of metabolism
5. Common renal disease
6. Urinary calculus
7. Urine examination for detection of abnormal constituents
8. Interpretation and Diagnosis through charts
9. Liver Function tests
10. Lipid Profile
11. Renal Function test
12. Cardiac markers
13. Blood gas and Electrolytes
14. Estimation of Blood sugar, Blood Urea and electrolytes
15. Demonstration of Strips
18
16. Demonstration of Glucometer
Internal Assessment
Theory - Average of two exams conducted. 20 marks
Practicals: Record & Lab work* 10 marks
* There shall be no University Practical Examination and internal assessment marks secured
in Practicals need not be sent to the University.
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 80 marks. Distribution of
type of questions and marks for Biochemistry shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 6 6 x 5 30
SHORT ANSWER (SA) 10 10 x 3 30
TOTAL MARKS 80
23
NO PRACTICAL EXAMINATION
REFERENCE BOOKS
Biochemistry
1. Varley - Clinical chemistry
2. TEITZ - Clinical chemistry
3. Kaplan - Clinical chemistry
4. Ramakrishna(S) Prasanna (KG), Rajna ® Text book of Medical Biochemistry Latest Ed
Orient longman Bombay -1980
5. Vasudevan (DM) Sreekumari(S) Text book of Biochemistry for Medical students, Latest
Edition
6. DAS (Debajyothi) Biochemistry Latest ED Academic, Publishers, Culcutta - 1992
7. Text Book of Medical Biochemistry - 3rd Edition, Orient Longman PVT Ltd
8. Practical Biochemistry for Medical Students - Rajagopal, Orient Longman PVT Ltd
19
PATHOLOGY
Histo Pathology, Clinical Pathology, Haematology and Blood Banking
Theory - 70 hours
Practical - 20 hours
HistoPathology - Theory
- Introduction to Histo Pathology
- Receiving of Specimen in the laboratory
- Grossing Techniques
- Mounting Techniques - various Mountants
- Maintenance of records and filing of the slides.
- Use & care of Microscope
- Various Fixatives, Mode of action, Preparation and Indication.
- Bio-Medical waste management
- Section Cutting
- Tissue processing for routine paraffin sections
- Decalcification of Tissues.
- Staining of tissues - H& E Staining
- Bio-Medical waste management
Clinical Pathology - Theory
- Introduction to Clinical Pathology
- Collection, Transport, Preservation, and Processing of various clinical specimens
- Urine Examination - Collection and Preservation of urine.
Physical, chemical, Microscopic Examination
- Examination of body fluids.
- Examination of cerebro spinal fluid (CSF)
- Sputum Examination.
- Examination of feces
Haematology - Theory
- Introduction to Haematology
20
- Normal constituents of Blood, their structure and function.
- Collection of Blood samples
- Various Anticoagulants used in Haematology
- Various instruments and glassware used in Haematology, Preparation and use of glassware
- Laboratory safety guidelines
- SI units and conventional units in Hospital Laboratory
- Hb, PCV
- ESR
- Normal Haemostasis
-Bleeding Time, Clotting Time, Prothrombin Time, Activated Partial Thromboplastin Time.
-Blood Bank-Introduction-Blood grouping and Rh Types-Cross matching
PRACTICALS
- Urine Examination.
- Physical, Chemical, Microscopy
- Blood Grouping Rh typing.
- Hb Estimation, PCV, ESR, Bleeding Time, Clotting Time.
- Histopathlogy - Section cutting and H &E Staining.
Internal Assessment
Theory - Average of two exams conducted. 20
Practicals: Record & Lab work* 10
* There shall be no University Practical Examination and internal assessment marks secured
in Practicals need not be sent to the University
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 80 marks. Distribution of
type ofquestions and marks for Pathology shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 6 6 x 5 30
21
SHORT ANSWER (SA) 10 10 x 3 30
TOTAL MARKS 80
NO PRACTICAL EXAMINATION
REFERENCE BOOKS
Pathology
1. Culling Histopathology techniques
2. Bancroft Histopathology techniques
3. Koss - cytology
4. Winifred greg - Diagnostic cytopathology
5. Orell - Cyto Pathology
6. Todd & Sanford Clinical Diagnosis by laboratory method
7. Dacie & Lewis - Practical Haematology
8. Ramanic Sood, Laboratory Technology (Methods and interpretation) 4th Ed. J.P. Bros,
New Delhi -1996)
9. Satish Gupta Short text book of Medical Laboratory for technician J.P. Bros, New Delhi -
1998
10. Sachdev K.N. Clinical Pathology and Bacteriology 8th Ed, J.P. Bros, New Delhi-1991.
11. Krishna - Text book of Pathology, Orient Longman PVT Ltd. Bacteriology 8th Ed, J.P. Bros,
New Delhi-
MICROBIOLOGY
Objective: - This course introduces the principles of Microbiology with emphasis on applied
aspectsof Microbiology of infectious diseases particularly in the following areas
- Principles & practice of sterilization methods.
-Collection and despatch of specimens for routine microbiological
investigations.Interpretation of commonly done bacteriological and serological
investigations.
22
-Control of Hospital infections
-Biomedical waste management
-Immunization schedule
Theory - 70 hours
1. Morphology 4 hours
Classification of microorgaisms, size, shape and structure of bacteria. Use of microscope in
the study of bacteria.
2. Growth and nutrition 4 hours
Nutrition, growth and multiplications of bacteria, use of culture media in diagnostic
bacteriology.
3. Sterilisation and Disinfection 4 hours
Principles and use of equipments of sterlization namely Hot Air oven, Autoclave and serum
Inspissrator. Pasteurization, Anti septic and disinfectants.
Antimicrobial sensitivity test
4. Immunology 6 hours
Immunity Vaccines, Types of Vaccine and immunization schedule Principles and
interpretation of commonly done serological tests namely Widal, VDRL, ASLO, CRP, RF &
ELISA. Rapid tests for HIV and HbsAg (Technical details to be avoided)
5. Systematic Bacteriology 20 hours
Morphology, cultivation, diseases caused, laboratory diagnosis including specimen
collection of the following bacteria (the classification, antigenic structure and pathogenicity
are not to be taught) Staphyloccci, Streptococci, Pneumococci, Gonococci, Menigococci, C
diphtheriae,Mycobacteria, Clostridia, Bacillus, Shigella, Salmonella, Esch coli, Klebsiella,
Proteus, vibrio cholerae, Pseudomonas & Spirochetes
6. Parasitology 10 hours
Morphology, life cycle, laboratory diagnosis of following parasites E. histolytica,
Plasmodium, Tape worms, Intestinal nematodes
7. Mycology 4 hours
Morphology, diseases caused and lab diagnosis of following fungi. Candida, Cryptococcus,
Dermatophytes, opportunistic fungi.
8. Virology 10 hours
23
General properties of viruses, diseases caused, lab diagnosis and prevention of following
viruses, Herpes, Hepatitis, HIV, Rabies and Poliomyelitis.
9. Hospital infection Causative agents, transmission methods, investigation, prevention and
control of Hospital infection. 4 hours
10. Principles and practice Biomedical waste management 4 hours
Practical 20 hours
Compound Microscope.
Demonstration and sterlization of equipments - Hot Air oven, Autoclave, Bacterial filters.
Demonstration of commonly used culture media, Nutrient broth, Nutrient agar, Blood agar,
Chacolate agar, Mac conkey medium, LJ media, Robertson Cooked meat media, Potassium
Tellurite media with growth, Mac with LF & NLF, NA with staph Antibiotic susceptibility test
Demonstration of common serological tests - Widal, VRDL, ELISA.
Grams stain
Acid fast staining
Stool exam for Helminthic ova
Visit to hospital for demonstration of biomedical waste mangement.
Anaerobic culture methods.
Internal Assessment
Theory - Average of two exams conducted. 20
Practicals: Record & Lab work* 10
* There shall be no University Practical Examination and internal assessment marks secured
in Practicals need not be sent to the University.
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 80 marks. Distribution of
type of questions and marks for Microbiology shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
24
SHORT ESSAY (SE) 6 6 x 5 30
SHORT ANSWER (SA) 10 10 x 3 30
TOTAL MARKS 80
NO PRACTICAL EXAMINATION
REFERENCE BOOKS
Microbiology
1. Anathanarayana & Panikar Medical Microbiology
2. Roberty Cruckshank - Medical Microbiology - The Practice of Medical Mircrobiology
3. Chatterjee - Parasitology - Interpretation to Clinical medicine.
4. Rippon - Medical Mycology
5. Emmons - Medical mycology
6. Basic laboratory methods in Parasitology, 1st Ed, J P Bros, New Delhi - 199
7. Basic laboratory procedures in clinical bacteriology, 1st Ed, J P Brothers, New Delhi.
II YEAR BSc DEGREE PERFUSION TECHNOLOGY SYLLABUS
APPLIED PHARMACOLOGY
• General concepts about pharmacodynamic and Pharmacokinetic Principles involved in
drug activity.
I. Autonomic nerves system.
• Anatomy & functional organisation.
• List of drugs acting an ANS including dose, route of administration, indications, contra
indications and adverse effects.
II. Cardiovascular drugs- Enumerate the mode of action, side effects and therapeutic uses of
the following drugs.
25
a. Antihypertensives
• Beta Adrenergic antagonists
• Alpha Adrenergic antagonists
• Peripheral Vasodilators
• Calcium channel blockers
b. Antiarrhythmic drugs
c. Cardiac glycosides
d. Sympathetic and nonsympathetic inotropic agents.
e. Coronary vasodilators.
f. Antianginal and anti failure agents
g. Lipid lowering & anti atherosclerotic drugs.
h. Drugs used in Haemostais - anticoagulants Thrombolytics and antithrombolytics.
i. Cardioplegic drugs- History, Principles and types of cardioplagia.
j. Primary solutions - History, principles & types.
k. Drugs used in the treatment of shock.
III. Anaesthetic agents.
• Definition of general and local anaesthetics.
• Classification of general anaesthetics.
• Pharmacokinetics and Pharmacodynamics of inhaled anaesthetic agents.
• Intravenous general anaesthetic agents.
• Local anaesthetics - classification mechanism of action, duration of action and methods to
prolong the duration of action. Preparation, dose and routes of administration.
IV. Analgessics
• Definition and classification• Routes of administration, dose, frequency of administration,
Side effects and management of non opioid and opiod analgesics
V. Antihistamines and antiemetics-• Classification, Mechanism of action, adverse effects,
Preparations, dose and routes and administration.
VI. CNS stimulants and depressants
• Alcohol
• Sedatives, hypnotics and narcotics
• CNS stimulants
26
• Neuromuscular blocking agents and muscle relaxants.
VII. Pharmacological protection of organs during CPB
VIII. Inhalational gases and emergency drugs.
IX. Pharmacotherapy of respiratory disorders
• Introduction - Modulators of bronchial smooth muscle tone and pulmonary vascular
smooth muscle tone
• Pharmacotherapy of bronchial asthma
• Pharmacotherapy of cough
• Mucokinetic and mucolytic agents
• Use of bland aerosols in respiratory care.
X. Corticosteroids - Classification, mechanism of action, adverse effects and
complications.Preparation, dose and routes of administration.
XI. Diuretics
• Renal physiology
• Side of action of diuretics
• Adverse effects
• Preparations, dose and routes of administrion.
XII. Chemotherapy of infections
• Definition
• Classification and mechanism of action of antimicrobial agents
• Combination of antimicrobial agents
• Chemoperophylaxis.
• Classification, spectrum of activity, dose, routes of administration and adverse effects of
penicillin, cephalosporins, aminoglycosides, tetracyclines, chloramphenicol, antitubercular
drugs.
XIII.Miscellaneous.
• IV fluids- various preparations and their usage.
• Electrolyte supplements
• Immunosuppressive agents
• New drugs included in perfusion technology.
• Drugs used in metabolic and electrolyte imbalance.
27
PRACTICALS:
1. Preparation and prescription of drugs of relevance.
2. Experimental pharmacology directed to show the effects of commonly used drugs of
relevance and Interpretation of few charts.
Scheme of Examination
Theory
There shall be one theory paper of three hours duration carrying 80 marks. Distribution of
type of questions and marks for applied Pharmacology shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 6 6 x 5 30
SHORT ANSWER (SA) 10 10 x 3 30
TOTAL MARKS 80
NO PRACTICAL EXAMINATION
Recommended Books.
1. R. S. Satoskar, S.D. Bhandarkar, S. S. Ainapure, Pharmacology and Pharmacotherapeutics,
18th Edition, single Volume, M/S Popular Prakashan, 350, Madan Mohan Marg,
Tardeo,Bombay - 400 034.
2. K.D. Tripathi, Essentials of Medical Pharmacology, V. Edition, M/s. Jaypee Brothers
3. Laurence and Bennet, Clinical Pharmacology, ELBS Edition, 9th Edition.
APPLIED PATHOLOGY
I. CARDIOVASCULAR SYSTEM
28
• Atherosclerosis- Definition, risk factors, briefly Pathogenesis & morphology, clinical
significance and prevention.
• Hypertension- Definition, types and briefly Pathogenesis and effects of Hypertension
• Aneurysms - Definition, classification, Pathology and complications.
• Pathophysiology of Heart failure
• Cardiac hypertrophy - causes, Pathophysiology & Progression to Heart Failure
• Ischaemic heart diseases- Definition, Types. Briefly Pathophysiology, Pathology &
Complications of IHD
• Valvular Heart diseases- causes, Pathology & complication. Complications of
artificialHeart valves.
• Cardiomyopathy - Definition, Types, causes and significance
• Pericardial effusion- causes, effects and diagnosis
• Congenital heart diseases - Basic defect and effects of important types of congenital heart
diseases.
II. HAEMATOLOGY
• Anaemia - Definition, morphological types and diagnosis of anaemia.Brief concept about
Haemolytic anaemia and polycythaemia.
• Leukocyte disorders- Briefly leukaemia, leukocytosis, agranulocytosis etc.
• Bleeding disorders- Definition, classification, causes & effects of important types of
bleeding disorders. Briefly various laboratory tests used to diagnose bleeding disorders.
III. RESPIRATORY SYSTEM
• Chronic obstructive airway diseases - Definition and types. Briefly causes, Pathology and
complications of each type of COPD.
• Briefly concept about obstructive versus restrictive pulmonary disease.
• Pneumoconiosis- Definition, types, Pathology and effects in brief.
• Pulmonary congestion and edema.
• Pleural effusion - causes, effects and diagnosis.
IV. RENAL SYSTEM
• Clinical manifestations of renal diseases. Briefly causes, mechanism, effects and lab
diagnosis of ARF & CRS. Briefly Glomerulonephritis and Pyelonephritis.
29
• End stage renal disease - Definition, causes, effects and role of dialysis and renal
transplantation in its management.
• Brief concept about obstructive uropathy.
PRACTICALS
1. Description & diagnosis of the following gross specimens.
a. Atherosclerosis-
b. Aortic aneurysm.-
c. Myocardial infraction.-
d. Emphysema-
e. Chronic glomerulonephritis.
f. Chronic pyelonephritis.
2. Interpretation & diagnosis of the following charts.
a. hematology Chart - AML, CML, Hemophilia, neutrophilia, eosinophilia.-
b. Urine Chart - ARF, CRF, AGN
3. Estimation of Hemoglobin.
4. Estimation Bleeding & Clotting time.
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 50 marks. Distribution of
type of questions and marks for Applied Pathology shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 3 3 x 5 15
SHORT ANSWER (SA) 5 5 x 2 15
TOTAL MARKS 50
30
PRACTICAL EXAMINATION 40 Marks.
There will be a Combined Practical examination for Applied Pathology & Applied
Microbiology.
Sl. No. Tests Marks
01 Interpretation of Hematology Chart 05
02 Interpretation of Urine Chart 05
03 Estimation of Hemoglobin 05
04 Estimation of Bleeding time & Clotting
time
05
Total 20
APPLIED MICROBIOLOGY
THEORY - 40 HOURS
1. Health care associated infections and Antimicrobial resistance: Infections that patients
acquire during the course of receiving treatment for other conditions within a healthcare
setting like Methicillin Resistant Staphylococcus aureus infections, Infections caused by
Clostriduium difficle, Vancomycin resistant enterococci etc. Catheter related blood stream
infections, Ventilator associated pneumonia, Catheter Related urinary tract infections,
Surveillance of emerging resistance and changing flora. The impact and cost attributed to
Hospital Associated infection. 6 Hours
2. Disease communicable to Healthcare workers in hospital set up and its preventive
measure: Occupationally acquired infections in healthcare professionals by respiratory route
(tuberculosis, varicella-zoster, respiratory synctial virus etc), blood borne transmission (HIV,
Hepatitis B, C, Cytomegalovirus, Ebola virus etc), oro faecal route (Salmonella, Hepatitis A
31
etc), direct contact (Herpes Simplex Virus etc). Preventive measures to combat the spread of
theseinfections by monitoring and control. 6 Hours
3. Microbiological surveillance and sampling: Required to determine the frequency of
potential bacterial pathogens including Streptococcus pneumoniae, Haemophilus
influenzae, and Moraxella catarrhalis and also to assess the antimicrobial
resistance.Sampling: rinse technique, direct surface agar plating technique.
6 Hours
4. Importance of sterilization:
a. Disinfection of instruments used in patient care: Classification, different methods,
advantages and disadvantages of the various methods.
b. Disinfection of the patient care unit
c. Infection control measures for ICU's 10 Hours
32
5. Sterilization:
a. Rooms: Gaseous sterilization, one atmosphere uniform glow discharge plasma (OAUGDP).
b. Equipments: classification of the instruments and appropriate methods of sterilization.
c. Central supply department: the four areas and the floor plan for instrument cleaning,
high-level disinfecting and sterilizing areas.
8 Hours
6. Preparation of materials for autoclaving: Packing of different types of materials, loading,
holding time and unloading.
4 Hours
PRACTICALS- 30 HOURS
1. Principles of autoclaving & quality control of Sterilization.
2. Collection of specimen from outpatient units, inpatient units, minor operation theater
and major operation theater for sterility testing.
3. The various methods employed for sterility testing.
4. Interpretation of results of sterility testing.
5. Disinfection of wards, OT and Laboratory.
Scheme of Examination
Theory
There shall be one theory paper of three hours duration carrying 50 marks. Distribution of
type of questions and marks for Applied Microbiology shall be as given under.
TYPE OF QUESTION NUMBER OF
QUESTIONS
MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 4 4 x 5 20
SHORT ANSWER (SA) 5 5 x 2 10
TOTAL MARKS 50
33
PRACTICAL EXAMINATION 40 Marks
There will be a Combined Practical examination for Applied Pathology & Applied
Microbiology.
No. Tests Marks
01 Dry heat / Moist heat: Temperature recording-charts interpretation 05
02 Dry heat / Moist heat: Colour change-indicators interpretation 05
03 Air sampling culture plates interpretation of Colony forming units
based on air flow rate and sampling time
05
04 Interpretation of Sterility of Haemodialysis water/Distilled water
/Deionised water based on growth of colonies in BHI agar to be
reported as X CFU/mL
05
Total 20
INTRODUCTION TO PERFUSION TECHNOLOGY
Basics of diagnostic techniques:
o Chest of X-ray-ECG-Echo-Angiography
o Nuclear Cardiology
o Laboratory investigations in relation to perfusion technology
o Cardiopulmonary bypass and perfusion technology
o History of Cardiac surgery and perfusion-Specific reference of Gibbon Lillehei, carrel
• Pre CPB surgery
• Azygous Flow principle.
• Hypothermic/nonhypothermic non-CPB surgery including gross's Well technique and
controlled cross circulation.
Monitoring and instrumentation
• Concepts of monitoring - instrumentation technology of ECG machine, pressure
transducer, syringe and peristaltic pumps, monitors, ventilators, pulse oximeters,
temperature probes and thermo regulatory monitoring, defibrillators and fibrillators. Piped
34
and non-piped gas delivery systems and connections. Basic physics related to medically used
gases.
• Haemodynamic monitoring• Haemostatic monitoring• Haemotologic monitoring
• Maintenance of oxygen, carbon dioxide and acid-base status and their monitoring
• Neurological monitoring (SSPE, EEG and cerebral function monitor)
• Aseptic technique.
• Cardiac surgery team, profession and terminology, scope of perfusion technology
Physiology of Extracorporeal circulation Heart - Lung machine
• Principles of extracorporeal circulation• Materials used in EC circuit
•Principles of extracorporeal gas exchange
47Various types of oxygenators
• Bubble oxygenators• Rotating spiral/cylinder/disc oxygenators
• Membrane oxygenators
• Mechanism of action components defoaming, rated flow.
Theory of blood pumps
• Ideal blood pump, pulsatile versus non-pulsatile flow, occlusive and non-occlusive pumps,
various types of pumps roller, bellow, sigmamotor, diaphragm, ventricular and centrifugal
pumps.
Element of extracorporeal circulation/hazards of:
a. Blood failure
b. Bubble trap
c. Flow meters
d. Temperatures
e. Heat exchanger
f. Regulating devices
Connection of the vascular system with extracorporeal circulation:
• Arterial and venous cannulae.
• Connecting tubes and connectors
• Vents
• Suckers
• Cardioplegia delivery system
35
• Venous drainage.
Haemodynamic of arterial return, venous drainage, cardioplegia Delivery and venting.
Blood banking, handling of blood products and their management. Blood components and
their use.
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 100 marks.
Distribution of type of questions and marks for Introduction to Perfusion Technology shall
be as given under
TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 12 12 x 5 60
SHORT ANSWER (SA) 10 10 x 2 20
TOTAL MARKS 100
PRACTICAL EXAMINATION 40 Marks
III YEAR B.Sc PERFUSION TECHNOLOGY
Paper-I Perfusion Technology Clinical
1. Pharmacokinetics and Pharmacodynamics of Cardiopulmonary bypass
2. Drugs (including anesthetic drugs) used in cardiopulmonary bypass
3. Conduct and monitoring of Cardiopulmonary bypass
4. Adequacy of perfusion - General considerations, specific aspects of perfusion, monitoring,
other concomitants which may affect its adequacy
5. Pulsatile perfusion - Introduction, theory & physiology of pulsatile flow, hemodynamic,
metabolic Effects, Clinical use, hematological effects
6. Cannulation techniques during cardaiopulmonary bypass
7. Termination of cardiopulmonary bypass - principles and methodology
8. Myocardial protection and cardioplegia- pretreatment of the Myocardium,cardioplegia,
hypothermia, controlled reperfusion, myocardial protection for specific clinical
problems,Complications of cardioplegia. Non cardioplegic methods during cardiac surgery
on cardiopulmonary bypass
36
9. Oxygenation - general consideration, bubble & membrane (including assessment and
comparison of oxygenator function)
10. Heat exchangers-principles function of heat exchangers & their assessment.
Complications related to heat exchange and their management
11. Priming fluids and hemodilution
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 100 marks. Distribution of
type of questions and marks for Paper-I - Perfusion Technology - Clinical shall be as given
under.
TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 12 12 x 5 60
SHORT ANSWER (SA) 10 10 x 2 20
TOTAL MARKS 100
PRACTICAL EXAMINATION
One common practical for all the three papers with equal weight age of marks i.e. 40
practical marks for each paper.
III YEAR B.Sc PERFUSION TECHNOLOGY
Paper-II Perfusion Technology – Applied
1. Blood cell trauma - analysis of forces of fluid motion, effects of physical forces o blood
cell, clinical effect. Complications of blood transfusion.
2. Anticoagulation on bypass, its monitoring, its reversal and complications. Heparin less
bypass. Platelet aggregation and platelet dysfunction. Coagulopathies due to
cardiopulmonary bypass and its management.
37
3. Inflammatory response to cardiopulmonary bypass & its clinical effects. Methods to
minimize the same. Immune response, neuroendocrine, renal, metabolic splanchnic
response, pulmonary response and electrolyte response to cardiopulmonary bypass
4. Blood conservation hemofiltration & dialysis during cardiopulmonary bypass including
modified ultra-filtration reverse autologous priming and other methods
5. Micro emboli- gaseous and particulate, filters used in cardiopulmonary bypass circuit.
6. Micro pore filtration during cardiopulmonary bypass
7. Counter pulsation techniques and assist devices
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 100 marks.
Distribution of type of questions and marks for Paper-II - Perfusion Technology Applied shall
be as given under.
TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 12 12 x 5 60
SHORT ANSWER (SA) 10 10 x 2 20
TOTAL MARKS 100
38
PRACTICAL EXAMINATION
One common practical for all the three papers with equal weight age of marks i.e. 40
practical marks for each paper.
III YEAR B.Sc PERFUSION TECHNOLOGY
Paper-III Perfusion Technology - Advanced
1. Perfusion techniques for Paediatric cardiac surgery
2. ECMO- special perfusion techniques for special cardiac surgeries and medical conditions
(Including thoracic aortic surgeries deep hypothermia and circulatory arrest).
Perfusion for non cardiac surgery, invasive cardiology and outside the operation suite.
3. Perfusion as a method of cardiopulmonary bypass
4. Complications and safety during cardiopulmonary bypass - bypass safety, organizational
aspects, accidents, coagulpathies, mechanical and electrical failures, perfusion
management, perfusion systems, safety for the perfusionist and surgical team management
of perfusion accidents.
5. Minimally invasive surgery and the perfusionist
6. Recent advances in perfusion techniques
7. Experimental perfusion
Scheme of Examination Theory
There shall be one theory paper of three hours duration carrying 100 marks.
Distribution of type of questions and marks for Paper-III - Perfusion Technology Advanced
shall be as given under.
TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL
LONG ESSAY (LE) 2 2 x 10 20
SHORT ESSAY (SE) 12 12 x 5 60
SHORT ANSWER (SA) 10 10 x 2 20
TOTAL MARKS 100
39
PRACTICAL EXAMINATION
One common practical for all the three papers with equal weight age of marks i.e. 40
practical Marks for each paper
2.11 No: of hours per subject
As given under clause “Content of each subject in each year “
2.12 Practical training
As given under clause “Content of each subject in each year “
2.13 Records
To be maintained for all Practical Work and duly signed by the supervising teacher
should be submitted at the time of University practical examination
2.14 Dissertation:
Not Applicable
2.15 Speciality training if any
Cardiology, Nephrology, Blood Bank, Sterilization Room, Anesthesia etc
according to the facility.
2.16 Project work to be done if any
Not Applicable
2.17 Any other requirements [CME, Paper Publishing etc.]
As per direction of HOD
2.18 Prescribed/recommended textbooks for each subject
Anatomy- Chaursia
Physiology-Chembulingam
Biochemistry-Vasudevan
40
Microbiology- Ananthanarayanan
Pathology-Harsh Mohan
Pharmacology-Tripathi
Medicine- Davidson
Perfusion Technology- Gravlee
2.19 Reference books
Anatomy
1 William Davis (P) understanding Human Anatomy and Physiology MC
Graw Hill
2. Chaursia –A Text book of Anatomy T.S. Ranganathan – A text book of Human
Anatomy
3.Fattana, Human anhiatomy (Description and applied) Saunder’s & C P Prism
Publishers, Bangalore – 1991
4. ESTER. M. Grishcimer, Physiology & Anatomy with Practical
Considerations, J.P. Lippin Cott. Philadelphia
5.Essential of Human embryology, Bhatnagar revised edition, Orient Longman PVT
L t d .
Physiology
1. Guyton (Arthur) Text Book of Physiology. Latest Ed. Prism publishers
2. Chatterjee(CC) Human Physiology Latest Ed. Vol-1, Medical Allied Agency
3. Choudhari (Sujith K) Concise Medical Physiology Latest Ed. New Central Book,
4. Ganong (William F) Review of Medical Physiology. Latest Ed. Appleton
Biochemistry
1. Varley – Clinical chemistry
1.TEITZ – Clinical chemistry
2.Kaplan – Clinical chemistry-Ramakrishna(S) Prasanna(KG), Rajna ® Text book of
Medical Biochemistry Latest Ed Orient longman Bombay –1980
3.Vasudevan (DM) Sreekumari(S) Text book of Biochemistry for Medical students
,Latest Ed
41
4.DAS(Debajyothi) Biochemistry Latest ED Academic, Publishers, Culcutta
5.Text Book of Medical Biochemistry – 3rd Edition, Orient Longman PVT Ltd
6.Practical Biochemistry for Medical Students – Rajagopal, Orient Longman PVT Ltd
Pathology
1. Culling Histopathology techniques
2.Bancroft Histopathology techniques
3.Koss – cytology
4.Winifred greg – Diagnostic cytopathology
5.Orell – Cyto Pathology
6.Todd & Sanford Clinical Diagnosis by laboratory method
7.Dacie & Lewis – Practical Haematology
8.Ramanic Sood, Laboratory Technology (Methods and interpretation) 4th Ed.
J.P. Bros, New Delhi –1996)
9.Satish Gupta Short text book of Medical Laboratory for technician J.P.
Bros, New Delhi – 1998 10.Sachdev K.N. Clinical Pathology and
Bacteriology 8th Ed, J.P. Bros, New Delhi-1991.
10. Krishna - Text book of Pathology, Orient Longman PVT Ltd.
Bacteriology 8th Ed, J.P.
Microbiology
1.Anathanarayana & Panikar Medical Microbioloty
2.Roberty Cruckshank – Medical Microbiology – The Practice of Medical
Mircrobiology
3.Chatterjee – Parasitology – Interpretation to Clinical medicine.
4.Rippon – Medical Mycology
5.Emmons – Medical mycology
6.Basic laboratory methods in Parasitology, 1st Ed, J P Bros, New Delhi – 199
7.Basic laboratory procedures in clinical bacteriology, 1st Ed, J P Brothers, New Delhi
2nd year Syllabus
APPLIED PHARMACOLOGY
Recommended Books.
42
1. R. S. Satoskar, S.D. Bhandarkar, S. S. Ainapure, Pharmacology and Pharmacotherapeutics,
18th Edition, single Volume, M/S Popular Prakashan,350, Madan Mohan Marg, Tardeo,
Bombay – 400 034.
2. K.D. Tripathi, Essentials of Medical Pharmacology, V. Edition, M/s. Jaypee Brothers, Post
Box, 7193, G-16, EMCA House, 23/23, Bansari Road, Daryaganj, New Delhi.
3. Laurence and Bennet, Clinical Pharmacology, ELBS Edition, 9th Edition
2.20 Journals
1. Annals of Thoracic surgery
2. Journal of Indian association of Perfusions
3. Journal of American Society of Extra corporeal Technicians
4. IACTS journal
2.21 Log book
To be maintained for all academic work which shall be counter signed by
concerned HOD

More Related Content

What's hot

Basic principles of myocardial proctection
Basic principles of myocardial proctectionBasic principles of myocardial proctection
Basic principles of myocardial proctectionRaja Lahiri
 
CORONARY ENGAGEMENT.pdf
CORONARY ENGAGEMENT.pdfCORONARY ENGAGEMENT.pdf
CORONARY ENGAGEMENT.pdfThieu Minh Son
 
cannulation techniques during cpb
cannulation techniques during cpbcannulation techniques during cpb
cannulation techniques during cpbManu Jacob
 
8.myocardial protection during cpb
8.myocardial protection during cpb8.myocardial protection during cpb
8.myocardial protection during cpbManu Jacob
 
CARDIO-PULMONARY BYPASS
CARDIO-PULMONARY BYPASSCARDIO-PULMONARY BYPASS
CARDIO-PULMONARY BYPASSSreevidya V S
 
Priming fluid and hemodilution
Priming fluid and hemodilutionPriming fluid and hemodilution
Priming fluid and hemodilutionManu Jacob
 
Basic Heart-Lung Machine in Cardiac Surgery
Basic Heart-Lung Machine in Cardiac SurgeryBasic Heart-Lung Machine in Cardiac Surgery
Basic Heart-Lung Machine in Cardiac SurgeryJenphop Khunjorn
 
Microemboli gaseous and particulate
Microemboli gaseous and particulateMicroemboli gaseous and particulate
Microemboli gaseous and particulateManu Jacob
 
7 Adequacy Of Perfusion During Cardiopulmonary Bypass
7 Adequacy Of Perfusion During Cardiopulmonary Bypass7 Adequacy Of Perfusion During Cardiopulmonary Bypass
7 Adequacy Of Perfusion During Cardiopulmonary BypassDang Thanh Tuan
 
Extracorporeal circulation - CPB, ECMO
Extracorporeal circulation - CPB, ECMOExtracorporeal circulation - CPB, ECMO
Extracorporeal circulation - CPB, ECMOaratimohan
 
Cardiopulmonary bypass
Cardiopulmonary bypassCardiopulmonary bypass
Cardiopulmonary bypassarunsagar25
 
Perfusionist... Prometric Exam Model Questions
Perfusionist... Prometric Exam Model QuestionsPerfusionist... Prometric Exam Model Questions
Perfusionist... Prometric Exam Model QuestionsManu Jacob
 
Blood cell Trauma
Blood cell TraumaBlood cell Trauma
Blood cell TraumaManu Jacob
 
History of cardiopulmonary bypass
History of cardiopulmonary bypass History of cardiopulmonary bypass
History of cardiopulmonary bypass Manu Jacob
 
Myocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SR
Myocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SRMyocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SR
Myocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SRDR NIKUNJ SHEKHADA
 
Blood pump perfusion
Blood pump perfusionBlood pump perfusion
Blood pump perfusionAkshayKatoch4
 
Complications and safety during cpb
Complications and safety during cpbComplications and safety during cpb
Complications and safety during cpbManu Jacob
 

What's hot (20)

Basic principles of myocardial proctection
Basic principles of myocardial proctectionBasic principles of myocardial proctection
Basic principles of myocardial proctection
 
CORONARY ENGAGEMENT.pdf
CORONARY ENGAGEMENT.pdfCORONARY ENGAGEMENT.pdf
CORONARY ENGAGEMENT.pdf
 
INTRA AORTIC BALLON PUMP (IABP)
INTRA AORTIC BALLON PUMP (IABP)INTRA AORTIC BALLON PUMP (IABP)
INTRA AORTIC BALLON PUMP (IABP)
 
cannulation techniques during cpb
cannulation techniques during cpbcannulation techniques during cpb
cannulation techniques during cpb
 
8.myocardial protection during cpb
8.myocardial protection during cpb8.myocardial protection during cpb
8.myocardial protection during cpb
 
CARDIO-PULMONARY BYPASS
CARDIO-PULMONARY BYPASSCARDIO-PULMONARY BYPASS
CARDIO-PULMONARY BYPASS
 
Priming fluid and hemodilution
Priming fluid and hemodilutionPriming fluid and hemodilution
Priming fluid and hemodilution
 
Basic Heart-Lung Machine in Cardiac Surgery
Basic Heart-Lung Machine in Cardiac SurgeryBasic Heart-Lung Machine in Cardiac Surgery
Basic Heart-Lung Machine in Cardiac Surgery
 
Microemboli gaseous and particulate
Microemboli gaseous and particulateMicroemboli gaseous and particulate
Microemboli gaseous and particulate
 
7 Adequacy Of Perfusion During Cardiopulmonary Bypass
7 Adequacy Of Perfusion During Cardiopulmonary Bypass7 Adequacy Of Perfusion During Cardiopulmonary Bypass
7 Adequacy Of Perfusion During Cardiopulmonary Bypass
 
Extracorporeal circulation - CPB, ECMO
Extracorporeal circulation - CPB, ECMOExtracorporeal circulation - CPB, ECMO
Extracorporeal circulation - CPB, ECMO
 
Cardiopulmonary bypass
Cardiopulmonary bypassCardiopulmonary bypass
Cardiopulmonary bypass
 
Perfusionist... Prometric Exam Model Questions
Perfusionist... Prometric Exam Model QuestionsPerfusionist... Prometric Exam Model Questions
Perfusionist... Prometric Exam Model Questions
 
Blood cell Trauma
Blood cell TraumaBlood cell Trauma
Blood cell Trauma
 
PTMC/PBMC
PTMC/PBMCPTMC/PBMC
PTMC/PBMC
 
History of cardiopulmonary bypass
History of cardiopulmonary bypass History of cardiopulmonary bypass
History of cardiopulmonary bypass
 
Cardiopulmonary bypass
Cardiopulmonary bypassCardiopulmonary bypass
Cardiopulmonary bypass
 
Myocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SR
Myocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SRMyocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SR
Myocardial protection DR NIKUNJ R SHEKHADA (MBBS ,MS GRN SURG , DNB CTS SR
 
Blood pump perfusion
Blood pump perfusionBlood pump perfusion
Blood pump perfusion
 
Complications and safety during cpb
Complications and safety during cpbComplications and safety during cpb
Complications and safety during cpb
 

Similar to b sc perfusion technology syllabus

A Checklist of Key Cardio-Respiratory Interventions.pdf
A Checklist of Key Cardio-Respiratory Interventions.pdfA Checklist of Key Cardio-Respiratory Interventions.pdf
A Checklist of Key Cardio-Respiratory Interventions.pdfMohammad Saeb Mohajeri
 
Postgraduate Certificate Musculoskeletal Ultrasound - Programme Summary
Postgraduate Certificate Musculoskeletal Ultrasound - Programme SummaryPostgraduate Certificate Musculoskeletal Ultrasound - Programme Summary
Postgraduate Certificate Musculoskeletal Ultrasound - Programme SummaryDr. Peter Resteghini
 
eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...
eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...
eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...NugrahaPranadipta
 
26_Applied Haematology – I.pdf
26_Applied Haematology – I.pdf26_Applied Haematology – I.pdf
26_Applied Haematology – I.pdfVamsi kumar
 
22_Fundamentals of Histology.pdf
22_Fundamentals of Histology.pdf22_Fundamentals of Histology.pdf
22_Fundamentals of Histology.pdfVamsi kumar
 
Wheeze & Stridor CBL 1s d fsefs fddfg f a t year corrected by Prof. Samia.pptx
Wheeze &  Stridor CBL 1s d fsefs fddfg f  a t year corrected by Prof. Samia.pptxWheeze &  Stridor CBL 1s d fsefs fddfg f  a t year corrected by Prof. Samia.pptx
Wheeze & Stridor CBL 1s d fsefs fddfg f a t year corrected by Prof. Samia.pptxsaeedapkli
 
Respiratory Care Anatomy and Physiology (3rd ed).pdf
Respiratory Care Anatomy and Physiology (3rd ed).pdfRespiratory Care Anatomy and Physiology (3rd ed).pdf
Respiratory Care Anatomy and Physiology (3rd ed).pdfJorgeAndrsMesa
 
HEC Curriculum of Doctor of Physical Therapy (DPT)
HEC Curriculum of Doctor of Physical Therapy (DPT)HEC Curriculum of Doctor of Physical Therapy (DPT)
HEC Curriculum of Doctor of Physical Therapy (DPT)Rana Waqar
 
Curriculum_.pdf
Curriculum_.pdfCurriculum_.pdf
Curriculum_.pdfSatasooyar
 
Uttara Adhunik Medical college & Hospital
Uttara Adhunik Medical college & HospitalUttara Adhunik Medical college & Hospital
Uttara Adhunik Medical college & HospitalAbdullah Mamun
 
1150 - Sita Kansagra.pdf
1150 - Sita Kansagra.pdf1150 - Sita Kansagra.pdf
1150 - Sita Kansagra.pdfjermaine34
 
INTRODUCTION TO COPD TRAINING PROGRAM.pptx
INTRODUCTION TO COPD TRAINING PROGRAM.pptxINTRODUCTION TO COPD TRAINING PROGRAM.pptx
INTRODUCTION TO COPD TRAINING PROGRAM.pptxVikrant569983
 
Assessment of the Critically Ill Patient in (.pptx
Assessment of the Critically Ill Patient in (.pptxAssessment of the Critically Ill Patient in (.pptx
Assessment of the Critically Ill Patient in (.pptxDrkAnwerAli
 
Элективный курс Хирурии.ppt
Элективный курс Хирурии.pptЭлективный курс Хирурии.ppt
Элективный курс Хирурии.pptssuser886f40
 
A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...
A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...
A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...ijtsrd
 

Similar to b sc perfusion technology syllabus (20)

M.tech clinical engineering
M.tech clinical engineeringM.tech clinical engineering
M.tech clinical engineering
 
A Checklist of Key Cardio-Respiratory Interventions.pdf
A Checklist of Key Cardio-Respiratory Interventions.pdfA Checklist of Key Cardio-Respiratory Interventions.pdf
A Checklist of Key Cardio-Respiratory Interventions.pdf
 
Postgraduate Certificate Musculoskeletal Ultrasound - Programme Summary
Postgraduate Certificate Musculoskeletal Ultrasound - Programme SummaryPostgraduate Certificate Musculoskeletal Ultrasound - Programme Summary
Postgraduate Certificate Musculoskeletal Ultrasound - Programme Summary
 
Curriculum Vitae MOHD FARID BIN MOHD TAUFIK
Curriculum Vitae MOHD FARID BIN MOHD TAUFIKCurriculum Vitae MOHD FARID BIN MOHD TAUFIK
Curriculum Vitae MOHD FARID BIN MOHD TAUFIK
 
eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...
eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...
eapci-core-curriculum-for-percutaneous-cardiovascular-interventions-2020commi...
 
26_Applied Haematology – I.pdf
26_Applied Haematology – I.pdf26_Applied Haematology – I.pdf
26_Applied Haematology – I.pdf
 
22_Fundamentals of Histology.pdf
22_Fundamentals of Histology.pdf22_Fundamentals of Histology.pdf
22_Fundamentals of Histology.pdf
 
Wheeze & Stridor CBL 1s d fsefs fddfg f a t year corrected by Prof. Samia.pptx
Wheeze &  Stridor CBL 1s d fsefs fddfg f  a t year corrected by Prof. Samia.pptxWheeze &  Stridor CBL 1s d fsefs fddfg f  a t year corrected by Prof. Samia.pptx
Wheeze & Stridor CBL 1s d fsefs fddfg f a t year corrected by Prof. Samia.pptx
 
Respiratory Care Anatomy and Physiology (3rd ed).pdf
Respiratory Care Anatomy and Physiology (3rd ed).pdfRespiratory Care Anatomy and Physiology (3rd ed).pdf
Respiratory Care Anatomy and Physiology (3rd ed).pdf
 
Tinkler2011
Tinkler2011Tinkler2011
Tinkler2011
 
HEC Curriculum of Doctor of Physical Therapy (DPT)
HEC Curriculum of Doctor of Physical Therapy (DPT)HEC Curriculum of Doctor of Physical Therapy (DPT)
HEC Curriculum of Doctor of Physical Therapy (DPT)
 
2010 ClinChem Annual Report
 2010 ClinChem Annual Report 2010 ClinChem Annual Report
2010 ClinChem Annual Report
 
Filiberto De La Garza resume
Filiberto De La Garza resumeFiliberto De La Garza resume
Filiberto De La Garza resume
 
Curriculum_.pdf
Curriculum_.pdfCurriculum_.pdf
Curriculum_.pdf
 
Uttara Adhunik Medical college & Hospital
Uttara Adhunik Medical college & HospitalUttara Adhunik Medical college & Hospital
Uttara Adhunik Medical college & Hospital
 
1150 - Sita Kansagra.pdf
1150 - Sita Kansagra.pdf1150 - Sita Kansagra.pdf
1150 - Sita Kansagra.pdf
 
INTRODUCTION TO COPD TRAINING PROGRAM.pptx
INTRODUCTION TO COPD TRAINING PROGRAM.pptxINTRODUCTION TO COPD TRAINING PROGRAM.pptx
INTRODUCTION TO COPD TRAINING PROGRAM.pptx
 
Assessment of the Critically Ill Patient in (.pptx
Assessment of the Critically Ill Patient in (.pptxAssessment of the Critically Ill Patient in (.pptx
Assessment of the Critically Ill Patient in (.pptx
 
Элективный курс Хирурии.ppt
Элективный курс Хирурии.pptЭлективный курс Хирурии.ppt
Элективный курс Хирурии.ppt
 
A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...
A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...
A Study to Assess the Level of Knowledge Regarding Airway Management Modaliti...
 

More from Manu Jacob

GOAL DIRECTED PERFUSION-------------------------------------------------
GOAL DIRECTED PERFUSION-------------------------------------------------GOAL DIRECTED PERFUSION-------------------------------------------------
GOAL DIRECTED PERFUSION-------------------------------------------------Manu Jacob
 
DHCA-in-a-Patient-with-Known-Cold-Agglutinin-Antibodies
DHCA-in-a-Patient-with-Known-Cold-Agglutinin-AntibodiesDHCA-in-a-Patient-with-Known-Cold-Agglutinin-Antibodies
DHCA-in-a-Patient-with-Known-Cold-Agglutinin-AntibodiesManu Jacob
 
COLD AGGLUTINS.pptx
COLD AGGLUTINS.pptxCOLD AGGLUTINS.pptx
COLD AGGLUTINS.pptxManu Jacob
 
WEANING FROM CPB.pptx
WEANING FROM CPB.pptxWEANING FROM CPB.pptx
WEANING FROM CPB.pptxManu Jacob
 
Norwood Procedure.pptx
Norwood Procedure.pptxNorwood Procedure.pptx
Norwood Procedure.pptxManu Jacob
 
Anomalous left coronary artery from the pulmonary artery
Anomalous left coronary artery from the pulmonary arteryAnomalous left coronary artery from the pulmonary artery
Anomalous left coronary artery from the pulmonary arteryManu Jacob
 
ROSS PROCEDURE
ROSS PROCEDUREROSS PROCEDURE
ROSS PROCEDUREManu Jacob
 
Lactate and cardiopulmonary bypass
Lactate and cardiopulmonary bypass Lactate and cardiopulmonary bypass
Lactate and cardiopulmonary bypass Manu Jacob
 
REYNOLDS NUMBER
REYNOLDS NUMBERREYNOLDS NUMBER
REYNOLDS NUMBERManu Jacob
 
Intra operative blood_conservation
Intra operative blood_conservationIntra operative blood_conservation
Intra operative blood_conservationManu Jacob
 
4.hemo filtration & blood conservation technique
4.hemo filtration & blood conservation technique4.hemo filtration & blood conservation technique
4.hemo filtration & blood conservation techniqueManu Jacob
 
Arterial blood gas.ppt1 (1)
Arterial blood gas.ppt1 (1)Arterial blood gas.ppt1 (1)
Arterial blood gas.ppt1 (1)Manu Jacob
 
Deep hypothermic circulatory arrest in pediatric cardiac sur
Deep hypothermic circulatory arrest in pediatric cardiac surDeep hypothermic circulatory arrest in pediatric cardiac sur
Deep hypothermic circulatory arrest in pediatric cardiac surManu Jacob
 
Immune system and inflamatory response to cpb(1)
Immune system and inflamatory response to cpb(1)Immune system and inflamatory response to cpb(1)
Immune system and inflamatory response to cpb(1)Manu Jacob
 
Complicationsandsafetyduringcpb 180414072601
Complicationsandsafetyduringcpb 180414072601Complicationsandsafetyduringcpb 180414072601
Complicationsandsafetyduringcpb 180414072601Manu Jacob
 
Cardiovascular drugs
Cardiovascular drugsCardiovascular drugs
Cardiovascular drugsManu Jacob
 
Cannulation and cardiopulmonary bypass.
Cannulation and cardiopulmonary bypass.Cannulation and cardiopulmonary bypass.
Cannulation and cardiopulmonary bypass.Manu Jacob
 
CARDIOPULMONARY BYPASS
CARDIOPULMONARY BYPASSCARDIOPULMONARY BYPASS
CARDIOPULMONARY BYPASSManu Jacob
 

More from Manu Jacob (20)

GOAL DIRECTED PERFUSION-------------------------------------------------
GOAL DIRECTED PERFUSION-------------------------------------------------GOAL DIRECTED PERFUSION-------------------------------------------------
GOAL DIRECTED PERFUSION-------------------------------------------------
 
DHCA-in-a-Patient-with-Known-Cold-Agglutinin-Antibodies
DHCA-in-a-Patient-with-Known-Cold-Agglutinin-AntibodiesDHCA-in-a-Patient-with-Known-Cold-Agglutinin-Antibodies
DHCA-in-a-Patient-with-Known-Cold-Agglutinin-Antibodies
 
COLD AGGLUTINS.pptx
COLD AGGLUTINS.pptxCOLD AGGLUTINS.pptx
COLD AGGLUTINS.pptx
 
WEANING FROM CPB.pptx
WEANING FROM CPB.pptxWEANING FROM CPB.pptx
WEANING FROM CPB.pptx
 
DHCA
DHCA DHCA
DHCA
 
Norwood Procedure.pptx
Norwood Procedure.pptxNorwood Procedure.pptx
Norwood Procedure.pptx
 
Anomalous left coronary artery from the pulmonary artery
Anomalous left coronary artery from the pulmonary arteryAnomalous left coronary artery from the pulmonary artery
Anomalous left coronary artery from the pulmonary artery
 
ROSS PROCEDURE
ROSS PROCEDUREROSS PROCEDURE
ROSS PROCEDURE
 
Lactate and cardiopulmonary bypass
Lactate and cardiopulmonary bypass Lactate and cardiopulmonary bypass
Lactate and cardiopulmonary bypass
 
REYNOLDS NUMBER
REYNOLDS NUMBERREYNOLDS NUMBER
REYNOLDS NUMBER
 
Ecmo book
Ecmo bookEcmo book
Ecmo book
 
Intra operative blood_conservation
Intra operative blood_conservationIntra operative blood_conservation
Intra operative blood_conservation
 
4.hemo filtration & blood conservation technique
4.hemo filtration & blood conservation technique4.hemo filtration & blood conservation technique
4.hemo filtration & blood conservation technique
 
Arterial blood gas.ppt1 (1)
Arterial blood gas.ppt1 (1)Arterial blood gas.ppt1 (1)
Arterial blood gas.ppt1 (1)
 
Deep hypothermic circulatory arrest in pediatric cardiac sur
Deep hypothermic circulatory arrest in pediatric cardiac surDeep hypothermic circulatory arrest in pediatric cardiac sur
Deep hypothermic circulatory arrest in pediatric cardiac sur
 
Immune system and inflamatory response to cpb(1)
Immune system and inflamatory response to cpb(1)Immune system and inflamatory response to cpb(1)
Immune system and inflamatory response to cpb(1)
 
Complicationsandsafetyduringcpb 180414072601
Complicationsandsafetyduringcpb 180414072601Complicationsandsafetyduringcpb 180414072601
Complicationsandsafetyduringcpb 180414072601
 
Cardiovascular drugs
Cardiovascular drugsCardiovascular drugs
Cardiovascular drugs
 
Cannulation and cardiopulmonary bypass.
Cannulation and cardiopulmonary bypass.Cannulation and cardiopulmonary bypass.
Cannulation and cardiopulmonary bypass.
 
CARDIOPULMONARY BYPASS
CARDIOPULMONARY BYPASSCARDIOPULMONARY BYPASS
CARDIOPULMONARY BYPASS
 

Recently uploaded

Karra SKD Conference Presentation Revised.pptx
Karra SKD Conference Presentation Revised.pptxKarra SKD Conference Presentation Revised.pptx
Karra SKD Conference Presentation Revised.pptxAshokKarra1
 
call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️
call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️
call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️9953056974 Low Rate Call Girls In Saket, Delhi NCR
 
Proudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptxProudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptxthorishapillay1
 
Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)cama23
 
Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)Mark Reed
 
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdfInclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdfTechSoup
 
ISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITY
ISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITYISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITY
ISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITYKayeClaireEstoconing
 
Transaction Management in Database Management System
Transaction Management in Database Management SystemTransaction Management in Database Management System
Transaction Management in Database Management SystemChristalin Nelson
 
Student Profile Sample - We help schools to connect the data they have, with ...
Student Profile Sample - We help schools to connect the data they have, with ...Student Profile Sample - We help schools to connect the data they have, with ...
Student Profile Sample - We help schools to connect the data they have, with ...Seán Kennedy
 
AMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdf
AMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdfAMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdf
AMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdfphamnguyenenglishnb
 
Virtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdf
Virtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdfVirtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdf
Virtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdfErwinPantujan2
 
How to do quick user assign in kanban in Odoo 17 ERP
How to do quick user assign in kanban in Odoo 17 ERPHow to do quick user assign in kanban in Odoo 17 ERP
How to do quick user assign in kanban in Odoo 17 ERPCeline George
 
ACC 2024 Chronicles. Cardiology. Exam.pdf
ACC 2024 Chronicles. Cardiology. Exam.pdfACC 2024 Chronicles. Cardiology. Exam.pdf
ACC 2024 Chronicles. Cardiology. Exam.pdfSpandanaRallapalli
 
Difference Between Search & Browse Methods in Odoo 17
Difference Between Search & Browse Methods in Odoo 17Difference Between Search & Browse Methods in Odoo 17
Difference Between Search & Browse Methods in Odoo 17Celine George
 
Judging the Relevance and worth of ideas part 2.pptx
Judging the Relevance  and worth of ideas part 2.pptxJudging the Relevance  and worth of ideas part 2.pptx
Judging the Relevance and worth of ideas part 2.pptxSherlyMaeNeri
 
Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...Jisc
 
Concurrency Control in Database Management system
Concurrency Control in Database Management systemConcurrency Control in Database Management system
Concurrency Control in Database Management systemChristalin Nelson
 

Recently uploaded (20)

Karra SKD Conference Presentation Revised.pptx
Karra SKD Conference Presentation Revised.pptxKarra SKD Conference Presentation Revised.pptx
Karra SKD Conference Presentation Revised.pptx
 
call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️
call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️
call girls in Kamla Market (DELHI) 🔝 >༒9953330565🔝 genuine Escort Service 🔝✔️✔️
 
Proudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptxProudly South Africa powerpoint Thorisha.pptx
Proudly South Africa powerpoint Thorisha.pptx
 
Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)Global Lehigh Strategic Initiatives (without descriptions)
Global Lehigh Strategic Initiatives (without descriptions)
 
Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)Influencing policy (training slides from Fast Track Impact)
Influencing policy (training slides from Fast Track Impact)
 
YOUVE_GOT_EMAIL_PRELIMS_EL_DORADO_2024.pptx
YOUVE_GOT_EMAIL_PRELIMS_EL_DORADO_2024.pptxYOUVE_GOT_EMAIL_PRELIMS_EL_DORADO_2024.pptx
YOUVE_GOT_EMAIL_PRELIMS_EL_DORADO_2024.pptx
 
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdfInclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
Inclusivity Essentials_ Creating Accessible Websites for Nonprofits .pdf
 
ISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITY
ISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITYISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITY
ISYU TUNGKOL SA SEKSWLADIDA (ISSUE ABOUT SEXUALITY
 
Transaction Management in Database Management System
Transaction Management in Database Management SystemTransaction Management in Database Management System
Transaction Management in Database Management System
 
Student Profile Sample - We help schools to connect the data they have, with ...
Student Profile Sample - We help schools to connect the data they have, with ...Student Profile Sample - We help schools to connect the data they have, with ...
Student Profile Sample - We help schools to connect the data they have, with ...
 
AMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdf
AMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdfAMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdf
AMERICAN LANGUAGE HUB_Level2_Student'sBook_Answerkey.pdf
 
Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝
Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝
Model Call Girl in Tilak Nagar Delhi reach out to us at 🔝9953056974🔝
 
Virtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdf
Virtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdfVirtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdf
Virtual-Orientation-on-the-Administration-of-NATG12-NATG6-and-ELLNA.pdf
 
How to do quick user assign in kanban in Odoo 17 ERP
How to do quick user assign in kanban in Odoo 17 ERPHow to do quick user assign in kanban in Odoo 17 ERP
How to do quick user assign in kanban in Odoo 17 ERP
 
ACC 2024 Chronicles. Cardiology. Exam.pdf
ACC 2024 Chronicles. Cardiology. Exam.pdfACC 2024 Chronicles. Cardiology. Exam.pdf
ACC 2024 Chronicles. Cardiology. Exam.pdf
 
Difference Between Search & Browse Methods in Odoo 17
Difference Between Search & Browse Methods in Odoo 17Difference Between Search & Browse Methods in Odoo 17
Difference Between Search & Browse Methods in Odoo 17
 
Judging the Relevance and worth of ideas part 2.pptx
Judging the Relevance  and worth of ideas part 2.pptxJudging the Relevance  and worth of ideas part 2.pptx
Judging the Relevance and worth of ideas part 2.pptx
 
Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...Procuring digital preservation CAN be quick and painless with our new dynamic...
Procuring digital preservation CAN be quick and painless with our new dynamic...
 
Raw materials used in Herbal Cosmetics.pptx
Raw materials used in Herbal Cosmetics.pptxRaw materials used in Herbal Cosmetics.pptx
Raw materials used in Herbal Cosmetics.pptx
 
Concurrency Control in Database Management system
Concurrency Control in Database Management systemConcurrency Control in Database Management system
Concurrency Control in Database Management system
 

b sc perfusion technology syllabus

  • 1. KERALA UNIVERSITY OF HEALTH SCIENCES Thrissur 680596 SYLLABUS UNDRE GRADUATE COURSE IN PERFUSION TECHNOLOGY Course Code 015 2016-17 admission onwards (Approved by the Academic Council) SYLLABUS2016
  • 2. 1 (This is excerpted from the draft Regulations document being prepared by the KUHS. Hence the numbering pattern is being retained) 2. COURSE CONTENT 2.1 Title of the course Bachelor of Science in Perfusion Technology (BSc. Perfusion technology) 2.2 Objectives of the Course- Perfusion Technology degree course is to provide a competent Cardiac Perfusionist who is well versed with modern technologies and up to date knowledge in patient care. A perfusionist, also known as a clinical perfusionist or a cardiovascular perfusionist, is a specialized healthcare professional who uses the heart-lung machine during cardiac surgery and other surgeries that require cardiopulmonary bypass to manage the patient's physiological status.The perfusionist is a highly trained member of the cardiothoracic surgical team which consists of cardiac surgeons, anesthesiologists, physician assistants, surgical technologists, and nurses. The perfusionist is solely responsible for the management of the physiological and metabolic needs of the cardiac surgical patient so that the cardiac surgeon may operate on a still, unbeating heart. This is accomplished through the utilization of the heart-lung machine, oxygenator, filters, reservoirs and tubing. The perfusionist is responsible for the management of circulatory and respiratory functions of the patient so that the cardiac surgeon can focus on the actual surgical procedure. Other responsibilities include autologous blood collection and processing, implementation and management of the intra-aortic balloon pump, adult and infant extracorporeal membrane oxygenation (ECMO), monitoring of anticoagulation, electrolyte, acid-base balance and blood-gas composition,placing and managing patients on ventricular assist devices as bridge to
  • 3. 2 recovery or heart transplantation and supporting patients receiving lung or liver transplants and in procurement of cardiothoracic donor organs for transplantation Cardiovascular Perfusion Technology involves the study of physiology, pathology and associated equipment used to support and/or assume the function of the heart and/or lungs during medical procedures. The perfusion technologist prepares and operates the heart-lung machine and other sophisticated equipment as directed by healthcare physicians. The perfusionist measures various blood and other parameters to identify appropriate mechanical, pharmacological and thermal manipulation to maintain tissue viability. To perform these tasks the perfusionist must have a thorough understanding of the both respiratory and circulatory systems and be able to operate complex equipment. Additionally the perfusionist must be capable of handling stressful situations, pay great attention to detail, communicate effectively, and be willing to stay abreast of new developments in the profession This course is to provide a framework to guide safe and effective cardiopulmonary bypass (CPB). Clinical teams implement the content of this document when developing institution-specific protocols for patients undergoing cardiac surgery utilizing CPB. A Perfusionist shall conduct cardiopulmonary bypass in compliance with departmental protocols. A patient-specific management plan for the cardiopulmonary bypass (CPB) procedure shall be prepared and communicated to the surgical team either during the pre- operative briefing or prior to beginning the procedure.The perfusionist should participate in the post-procedure debrief with the surgical team. The mission of the KUHS is to encourage and foster the development of the profession of clinical perfusion through education and certification, so as to provide optimum patient care. A perfusionist shall recognize that the term “professional ethics” incorporates a commitment to service, to competent practice and to consistent development for the benefit of the community. This code shall guide the conduct of the perfusionist in all circumstances. Perfusionist who has successfully completed an accredited educational program and has successfully taken the
  • 4. 3 examinations set by KUHS and BSc Perfusion Technology Degree will be awarded to them. The goals of the Degree are diverse and include: -development of professional standards for perfusion - enhancement of perfusion scope of practice - development of continuing education programs on national and regional levels - support of educational programs for entering perfusionists - scientific dissemination of knowledge 2.3 Medium of Instruction The medium of instruction for the course shall be English. 2.4 Course outline As given in curriculum 2.5 Duration Duration shall be for a period of four years including one year internship training. 2.6 Subjects As given curriculum 2.7 Total number of hours The number of hours of teaching theory and practical subject wise in first year, second year and third year are shown in Table-I, Table-II and Table-III Table - I Distribution of Teaching Hours in First Year Subjects
  • 5. 4 Main Subjects SL NO Subject Theory No Of Hrs Practical No Of Hrs Total No. of Hours 1 Human Anatomy 70 20 90 2 Physiology 70 20 90 3 Biochemistry 70 20 90 4 Pathology-[Clinical pathology, Haemotology & Blood –Banking] 70 20 90 5 Microbiology 70 20 90 Total 350 100 450 The classes in main subjects are to be held from Monday to Thursday. On Fridays and Saturdays students shall work in hospitals in the respective specialty or department chosen by them Clinical/Lab posting -470Hours- Fri day 9am - 1pm and 2pm - 4-30 pm Saturday 9am - 1pm Table - II Distribution of Teaching Hours in Second Year Subjects Main Subjects-No of hrs SL NO Subject Theory Practical Clinical Posting Total Hours 1 Medicine relevant to perfusion technology 50 - - - - 50
  • 6. 5 2 Section A Applied Pathology 30 30 - - 60 3 Section B Applied Microbiology 30 30 60 4 Applied Pharmacology 50 - - 50 5 Introduction to Perfusion Technology 80 100 65 0 830 Total 240 160 65 0 1050 Table -III Distribution of Teaching Hours in Third Year Subjects Main Subjects-No of hrs S L No Subje ct Theory Practical Clinical posting Tota l Hour s 1 Perfusion Technology – Clinical 50 50 25 0 350 2 Perfusion Technology – Applied 50 50 25 0 350 3 Perfusion Technology – Advanced 50 50 25 0 350 Total 15 0 15 0 75 0 105 0 2.8 Branches if any with definition Not applicable 2.9 Teaching Learning methods  Lecture and practical classes  During the internship year the candidates should do 5 months of internship is in an external institute (approved by KUHS) and the remaining 5 months in the parent institute.
  • 7. 6 2.10 Content of each subject in each year ANATOMY No. of theory classes: 70 hours No. of practical classes: 20 hours 1.Introduction: human body as a whole Theory: Definition of anatomy and its divisions Terms of location, positions and planes Cell and its organelles Epithelium-definition, classification, describe with examples, function Glands- classification, describe serous & mucous glands with examples Basic tissues - classification with examples Practical: Histology of types of epithelium Histology of serous, mucous & mixed salivary gland 2.Locomotion and support Theory: Cartilage - types with example & histology Bone - Classification, names of bone cells, parts of long bone, microscopy of compact bone, Names of all bones, vertebral column, intervertebral disc, fontanelles of fetal skull Joints - Classification of joints with examples, synovial joint (in detail for radiology) Muscular system: Classification of muscular tissue & histology Names of muscles of the body Practical: Histology of the 3 types of cartilage Demo of all bones showing parts, radiographs of normal bones & joints Histology of compact bone (TS & LS) Demonstration of all muscles of the body Histology of skeletal (TS & LS), smooth & cardiac muscle
  • 8. 7 3. Cardiovascular system Theory: Heart-size, location, chambers, exterior & interior Blood supply of heart Systemic & pulmonary circulation Branches of aorta, common carotid artery, subclavian artery, axillary artery, brachial artery, Superficial palmar arch, femoral artery, internal iliac artery Peripheral pulse Inferior venacava, portal vein, portosystemic anastomosis Great saphenous vein Dural venous sinuses Lymphatic system- cisterna chyli & thoracic duct Histology of lymphatic tissues Names of regional lymphatics, axillary and inguinal lymph nodes in brief Practical: Demonstration of heart and vessels in the body 12 Histology of large artery, medium sized artery & vein, large vein Microscopic appearance of large artery, medium sized artery & vein, Large vein pericardium Histology of lymph node, spleen, tonsil & thymus Normal chest radiograph showing heart shadows Normal angiograms 4. Gastro-intestinal system Theory: Parts of GIT, Oral cavity (lip, tongue (with histology), tonsil, dentition, pharynx, salivary glands, Waldeyer's ring) Oesophagus, stomach, small and large intestine, liver, gall bladder, pancreas Radiographs of abdomen 5. Respiratory system Parts of RS, nose, nasal cavity, larynx, trachea, lungs, bronchopulmonary segments Histology of trachea, lung and pleura Names of paranasal air sinuses
  • 9. 8 Practical: Demonstration of parts of respiratory system. Normal radiographs of chest Histology of lung and trachea 6. Peritoneum Theory: Description in brief Practical: Demonstration of reflections 7. Urinary system Kidney, ureter, urinary bladder, male and female urethra Histology of kidney, ureter and urinary bladder Practical: Demonstration of parts of urinary system Histology of kidney, ureter, urinary bladder Radiographs of abdomen-IVP, retrograde cystogram 8. Reproductive system Theory: Parts of male reproductive system, testis, vas deferens, epididymis, prostate (gross & histology) Parts of female reproductive system, uterus, fallopian tubes, ovary (gross & histology) Mammary gland - gross Practical: Demonstration of section of male and female pelves with organs in situ Histology of testis, vas deferens, epididymis, prostate, uterus, Fallopian tubes, ovary Radiographs of pelvis - hysterosalpingogram 9. Endocrine glands Theory: Names of all endocrine glands in detail on pituitary gland, thyroid gland, parathyroid gland, Suprarenal gland - (gross & histology) Practical: Demonstration of the glands 13 Histology of pituitary, thyroid, parathyroid, suprarenal glands 10. Nervous system Theory: Neurons, Classification of NS
  • 10. 9 Cerebrum, cerebellum, midbrain, pons, medulla oblongata, spinal cord with spinal nerve (gross &histology) Meninges, Ventricles & cerebrospinal fluid, Names of basal nuclei, Blood supply of brain, Cranial nerves.Sympathetic trunk & names of parasympathetic ganglia Practical: Histology of peripheral nerve & optic nerve Demonstration of all plexuses and nerves in the body Demonstration of all part of brain Histology of cerebrum, cerebellum, spinal cord 11. Sensory organs: Theory: Skin: Skin-histology, Appendages of skin Eye: parts of eye & lacrimal apparatus, Extra-ocular muscles & nerve supply Ear: parts of ear- external, middle and inner ear and contents Practical: Histology of thin and thick skin Demonstration and histology of eyeball Histology of cornea & retina 12. Embryology Theory: Spermatogenesis & oogenesis Ovulation, fertilization Fetal circulation Placenta Theory Type of Questions No. of Marks
  • 11. 10 Questions Sub-total Long Essay (LE) 2 2 x 10 20 Short Essay (SE) 6 6 x 5 30 Short Answer (SA) 10 10 x 3 30 Total Marks 80 There shall be one theory paper of three hours duration carrying 80 marks. Distribution of type of questions and marks for Anatomy shall be as given under NO PRACTICAL EXAMINATION REFERENCE BOOKS Anatomy 1. William Davis (P) understanding HumanAnatomy and Physiology MC Graw Hill 2. Chaursia -A Text book of Anatomy T.S. Ranganathan - A text book of Human Anatomy 3. Fattana, Human anatomy (Description and applied) Saunder’s & C P Prism Publishers, Bangalore - 1991 4. ESTER. M. Grishcimer, Physiology & Anatomy with PracticalConsiderations, J.P. Lippin Cott. Philadelphia 5. Essential of Human embryology, Bhatnagar revised edition, Orient Longman PVT Ltd.
  • 12. 11 PHYSIOLOGY Theory 70 hours Practical 20hours 1.Introduction - composition and function of blood Red blood cells - Erythropoiesis, stages of differentiation function, count physiological Variation. Haemoglobin -structure, functions, concentration physiological variation Methods of Estimation of Hb White blood cells - Production, function, life span, count, differential count Platelets - Origin, normal count, morphology functions. Plasma Proteins - Production, concentration, types, albumin, globulin, Fibrinogen, Prothrombin, Functions. Haemostasis & Blood coagulation Haemostasis - Definition, normal haemostasis, clotting factors, mechanism of clotting, disordersof clotting factors. 2.Blood Bank Blood groups - ABO system, Rh system, Blood grouping & typing, Crossmatching Rh system - Rh factor, Rh in compatibility. Blood transfusion - Indication, universal donor and recipient concept, Selection criteria of a blood donor. Transfusion reactions Anticoagulants - Classification, examples and uses 3.Anaemias: Classification - morphological and etilogical. Effects of anemia on body Blood indices - Colour index, MCH, MCV, MCHC Erythrocyte sedementation Rate (ESR) and Paced cell volume, Normal values, Definition. Determination, 4.Blood Volume -Normal value, determination of blood volume and its regulation Body fluid - pH, normal value, regulation and variation Lymph - lymphoid tissue formation, circulation, composition and function of lymph
  • 13. 12 5.Cardiovascular system Heart - Physiological Anatomy, Nerve supply Properties of Cardiac muscle, Cardiac cycle-systole, diastole. Intraventricular pressure curves.Cardiac Output - only definition Heart sounds- Normal heart sounds Areas of auscultation. Blood Pressure - Definition, normal value, clinical measurement of blood pressure. Physiological variations, regulation of heart rate, cardiac shock, hypotension, hypertension. Pulse - Jugalar, radial pulse, Triple response Heart sounds - Normal heart sounds, cause characteristics and signification. Heart rate Electrocardiogram - (ECG) -significance. 6.Digestive System - Physiological anatomy of Gastro intestinal tractand its functions Salivary glands-Stucture and functions. Deglutination -stages and regulation Stomach - structure and fuctions Gastric secretion - Composition function regulation of gastric juice secretion Pancrease - structure, function, composition, regulation of pancreatic juice 7.Liver - functions of liver, Bile secretion, composition, function regulation of bile secretion .Bilirubin metabolism types of bilirubin, Vandernberg reaction, Jaundice- types, and significance. Gall bladder - functions Intestine - small intestine and large intestine Small intestine -Functions- Digestive, absorption, movements. Large intestine - Functions, Digestion and absorption of Carbohydrates, Proteins, Fats, Lipids.Defecation 8.Respiratory system-Functions of Respiratory system, Physiological Anatomy of Respiratory system, Respiratory tract,Respiratory Muscles, Respiratory organ-lungs, Alveoli, Respiratory membrane, stages of respiration.Mechanism of normal and rigorous respiration. Forces opposing and favouring expansion of thelungs. Intra pulmonary pleural pressure, surface tension, recoil tendency of the wall. Transportation of Respiratory gases: Transportation of Oxygen: Direction, pressure gradient, Forms of transportation, Oxygenation of Hb. Quantity of Oxygen transported. 9.Lung volumes and capacities
  • 14. 13 Regulation of respiration what? Why? How? Mechanisms of Regulation, nervous and chemical regulation. Respiratory centre. Hearing Bruer Reflexes. Applied Physiology and Respiration: Hypoxia, Cyanosis, Asphyxia, Dyspnea, Dysbarism, Artificial Respiration, Apnoea. 10.Endocrine System - Definition Classification of Endocrine glands & their Harmones Properties of Harmones. Thyroid gland hormone - Physiological, Anatomy, Hormone scerated, Physiological function, regulation of secretion. Disorders - hypo and hyper secretion of hormone Adrenal gland, Adrenal cortex physiologic anatomy of adrenal gland, Adrenal cortex, cortical hormones - functions and regulation Adrenal medulla - Hormones, regulation and secretion. Functions of Adrenaline and nor adrenaline Pituitary hormones - Anterior and posterior pituitary hormones, secretion, function Pancreas - Hormones of pancreas Insulin - secretion, regulation, function and action Diabetes mellitus - Regulation of blood glucose level Parathyroid gland - function, action, regulation of secretion of parathyroid hormone. Calcitonin - function and action 11.Special senses Vision - structure of eye. Function of different parts.Structure of retina Hearing structure and function of can mechanism of hearing Taste - Taste buds functions. Smell physiology, Receptors. 12. Nervous system Functions of Nervous system, Neurone structure, classification and properties. Neuroglia, nerve fiber, classification, conduction of impulses continuous and saltatory. Velocity of impulse transmission and factors affecting. Synapse - structure, types, properties. Receptors - Definition, classification, properties. Reflex action - unconditioned properties of reflex action. Babinski's sign. Spinal cord nerve tracts. Ascending tracts, Descending tracts - pyramidal tracts - Extrapyramidal tracts. Functions of Medulla, pons, hypothalamic disorders. Cerebral cortex lobes and functions, Sensory cortex, Motor cortex, Cerebellum functions of
  • 15. 14 Cerebellum.Basal ganglion-funtions. EEG. Cerebro Spinal Fluid (CSF): formation, circulation, properties, composition and functions lumbar puncture. Autonomic Nervous System: Sympathetic and parasympathetic distribution and functions and comparison of functions. 13 Excretory System, Excretory organs Kidneys: Functions of kidneys structural and functional unit nepron, vasarecta, cortical and Juxtamedullary nephrons - Comparision, Juxta Glomerular Apparatus -Structure and function. Renal circulation peculiarities. Mechanism of Urine formation: Ultrafiltration criteria for filtration GFR, Plasma fraction, EFP, factors effecting EFR. Determination of GFR selective reabsorption - sites of reabsorptionsubstance reabsorbed, mechanisms of reabsorption Glucose, and urea. H + Cl aminoacids etc. TMG, Tubular lead, renal threshold % of reabsorption of different Substances, selective e secretion. Properties and composition of normal urine, urine output. Abnormal constituents in urine, Mechanism of urine concentration.Counter - Current Mechanisms: Micturition, Innervation of Bladder, Cysteurethrogram. Diuretics: Water, Diuretics, osmotic diuretics, artificial kidney renal function tests – plasma clearance Actions of ADH, Aldosterone and PTH on kidneys. Renal function tests 14 Reproductive system Function of Reproductive system, Puberty, male reproductive system. Functions of testes, Spermatogenesis site, stages, factors influencing semen. Endocrine functions of testes Androgens - Testosterone structure and functions. Female reproducive syustem. Ovulation, Menstrual cycle. Physiological changes during pregnancy, pregnancy test. Lactation: Composition of milk factors controlling lactation. 15 Muscle nerve physiology Classification of muscle, structure of skeletal muscle, Sarcomere contractile proteins, Neuromuscular junction. Transmission across, neuromuscular junction. Excitation contractioncoupling. Mechanism of muscle contraction muscle tone, fatigue Rigour mortis 16 Skin -structure and function
  • 16. 15 Body temperature measurement, Physiological variation, Regulation of body Temperature by physical chemical and nervous mechanisms .Role of Hypothalamus, Hypothermia and fever. Practicals Haemoglobinometry White Blood Cell count Red Blood Cell count Determination of Blood Groups Leishman's staining and Differential WBC count Determination of packed cell Volume Erythrocyte sedimentation rate [ESR] Calculation of Blood indices Determination of Clotting Time, Bleeding Time Blood pressure Recording Auscultation for Heart Sounds Artificial Respiration Determination of vital capacity Internal Assessment Theory - Average of two exams conducted. 20 Practicals: Record & Lab work* 10 * There shall be no University Practical Examination and internal assessment marks secured in Practicals need not be sent to the University. Theory There shall be one theory paper of three hours duration carrying 80 marks. Distribution of type of questions and marks for Physiology shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL
  • 17. 16 LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 6 6 x 5 30 SHORT ANSWER (SA) 10 10 x 3 30 TOTAL MARKS 80 NO PRACTICAL EXAMINATION REFERENCE BOOKS Physiology 1. Guyton (Arthur) Text Book of Physiology. Latest Ed. Prism publishers 2. Chatterjee (CC) Human Physiology Latest Ed. Vol-1, Medical Allied Agency 3. Choudhari (Sujith K) Concise Medical Physiology Latest Ed. New Central Book, 4. Ganong BIOCHEMISTRY 1. Carbohydrates -Classification and reactions of carbohydrates -Metabolism of carbohydrate -Glycolysis, Gluconeogenesis, -Significance of HMP shunt pathway, -Glycogen metabolism, regulation of blood glucose -Diabetes mellitus –classification, metabolic derangement, complication and monitori 2. Lipids -Classification of lipids, Biomembrane, importance of PUFA -Metabolism of lipids -Oxidation of fatty acids, synthesis of fatty acids, cholesterol, lipoproteins, dyslipidemias 3. Proteins. -Structure of protein with examples, Classification of amino acids
  • 18. 17 -Compounds formed from amino acids, -inborn errors of metabolism of amino acids 4. Enzymes. -Classification, Kinetics, enzyme inhibition, regulation of enzyme action, clinical enzymology 5. Acid base balance. -Regulation of normal blood pH, derangements in acid base status, compensatory mechanisms, anion-gap, arterial blood gas analysis. 6. Water and Electrolyte balance 7. Hemoglobin.Synthesis of heme, porphyria, degradation of heme, Jaundice. 8. LFT, RFT 9. Vitamins.-Fat soluble vitamins, water soluble vitamins 10. Minerals.Calcium and Iron in detail, selenium, copper, zinc, Phosphorus PRACTICALS 1. Analysis of Normal Urine 2. Composition of urine 3. Procedure for routine screening 4. Urinary screening for inborn errors of metabolism 5. Common renal disease 6. Urinary calculus 7. Urine examination for detection of abnormal constituents 8. Interpretation and Diagnosis through charts 9. Liver Function tests 10. Lipid Profile 11. Renal Function test 12. Cardiac markers 13. Blood gas and Electrolytes 14. Estimation of Blood sugar, Blood Urea and electrolytes 15. Demonstration of Strips
  • 19. 18 16. Demonstration of Glucometer Internal Assessment Theory - Average of two exams conducted. 20 marks Practicals: Record & Lab work* 10 marks * There shall be no University Practical Examination and internal assessment marks secured in Practicals need not be sent to the University. Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 80 marks. Distribution of type of questions and marks for Biochemistry shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 6 6 x 5 30 SHORT ANSWER (SA) 10 10 x 3 30 TOTAL MARKS 80 23 NO PRACTICAL EXAMINATION REFERENCE BOOKS Biochemistry 1. Varley - Clinical chemistry 2. TEITZ - Clinical chemistry 3. Kaplan - Clinical chemistry 4. Ramakrishna(S) Prasanna (KG), Rajna ® Text book of Medical Biochemistry Latest Ed Orient longman Bombay -1980 5. Vasudevan (DM) Sreekumari(S) Text book of Biochemistry for Medical students, Latest Edition 6. DAS (Debajyothi) Biochemistry Latest ED Academic, Publishers, Culcutta - 1992 7. Text Book of Medical Biochemistry - 3rd Edition, Orient Longman PVT Ltd 8. Practical Biochemistry for Medical Students - Rajagopal, Orient Longman PVT Ltd
  • 20. 19 PATHOLOGY Histo Pathology, Clinical Pathology, Haematology and Blood Banking Theory - 70 hours Practical - 20 hours HistoPathology - Theory - Introduction to Histo Pathology - Receiving of Specimen in the laboratory - Grossing Techniques - Mounting Techniques - various Mountants - Maintenance of records and filing of the slides. - Use & care of Microscope - Various Fixatives, Mode of action, Preparation and Indication. - Bio-Medical waste management - Section Cutting - Tissue processing for routine paraffin sections - Decalcification of Tissues. - Staining of tissues - H& E Staining - Bio-Medical waste management Clinical Pathology - Theory - Introduction to Clinical Pathology - Collection, Transport, Preservation, and Processing of various clinical specimens - Urine Examination - Collection and Preservation of urine. Physical, chemical, Microscopic Examination - Examination of body fluids. - Examination of cerebro spinal fluid (CSF) - Sputum Examination. - Examination of feces Haematology - Theory - Introduction to Haematology
  • 21. 20 - Normal constituents of Blood, their structure and function. - Collection of Blood samples - Various Anticoagulants used in Haematology - Various instruments and glassware used in Haematology, Preparation and use of glassware - Laboratory safety guidelines - SI units and conventional units in Hospital Laboratory - Hb, PCV - ESR - Normal Haemostasis -Bleeding Time, Clotting Time, Prothrombin Time, Activated Partial Thromboplastin Time. -Blood Bank-Introduction-Blood grouping and Rh Types-Cross matching PRACTICALS - Urine Examination. - Physical, Chemical, Microscopy - Blood Grouping Rh typing. - Hb Estimation, PCV, ESR, Bleeding Time, Clotting Time. - Histopathlogy - Section cutting and H &E Staining. Internal Assessment Theory - Average of two exams conducted. 20 Practicals: Record & Lab work* 10 * There shall be no University Practical Examination and internal assessment marks secured in Practicals need not be sent to the University Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 80 marks. Distribution of type ofquestions and marks for Pathology shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 6 6 x 5 30
  • 22. 21 SHORT ANSWER (SA) 10 10 x 3 30 TOTAL MARKS 80 NO PRACTICAL EXAMINATION REFERENCE BOOKS Pathology 1. Culling Histopathology techniques 2. Bancroft Histopathology techniques 3. Koss - cytology 4. Winifred greg - Diagnostic cytopathology 5. Orell - Cyto Pathology 6. Todd & Sanford Clinical Diagnosis by laboratory method 7. Dacie & Lewis - Practical Haematology 8. Ramanic Sood, Laboratory Technology (Methods and interpretation) 4th Ed. J.P. Bros, New Delhi -1996) 9. Satish Gupta Short text book of Medical Laboratory for technician J.P. Bros, New Delhi - 1998 10. Sachdev K.N. Clinical Pathology and Bacteriology 8th Ed, J.P. Bros, New Delhi-1991. 11. Krishna - Text book of Pathology, Orient Longman PVT Ltd. Bacteriology 8th Ed, J.P. Bros, New Delhi- MICROBIOLOGY Objective: - This course introduces the principles of Microbiology with emphasis on applied aspectsof Microbiology of infectious diseases particularly in the following areas - Principles & practice of sterilization methods. -Collection and despatch of specimens for routine microbiological investigations.Interpretation of commonly done bacteriological and serological investigations.
  • 23. 22 -Control of Hospital infections -Biomedical waste management -Immunization schedule Theory - 70 hours 1. Morphology 4 hours Classification of microorgaisms, size, shape and structure of bacteria. Use of microscope in the study of bacteria. 2. Growth and nutrition 4 hours Nutrition, growth and multiplications of bacteria, use of culture media in diagnostic bacteriology. 3. Sterilisation and Disinfection 4 hours Principles and use of equipments of sterlization namely Hot Air oven, Autoclave and serum Inspissrator. Pasteurization, Anti septic and disinfectants. Antimicrobial sensitivity test 4. Immunology 6 hours Immunity Vaccines, Types of Vaccine and immunization schedule Principles and interpretation of commonly done serological tests namely Widal, VDRL, ASLO, CRP, RF & ELISA. Rapid tests for HIV and HbsAg (Technical details to be avoided) 5. Systematic Bacteriology 20 hours Morphology, cultivation, diseases caused, laboratory diagnosis including specimen collection of the following bacteria (the classification, antigenic structure and pathogenicity are not to be taught) Staphyloccci, Streptococci, Pneumococci, Gonococci, Menigococci, C diphtheriae,Mycobacteria, Clostridia, Bacillus, Shigella, Salmonella, Esch coli, Klebsiella, Proteus, vibrio cholerae, Pseudomonas & Spirochetes 6. Parasitology 10 hours Morphology, life cycle, laboratory diagnosis of following parasites E. histolytica, Plasmodium, Tape worms, Intestinal nematodes 7. Mycology 4 hours Morphology, diseases caused and lab diagnosis of following fungi. Candida, Cryptococcus, Dermatophytes, opportunistic fungi. 8. Virology 10 hours
  • 24. 23 General properties of viruses, diseases caused, lab diagnosis and prevention of following viruses, Herpes, Hepatitis, HIV, Rabies and Poliomyelitis. 9. Hospital infection Causative agents, transmission methods, investigation, prevention and control of Hospital infection. 4 hours 10. Principles and practice Biomedical waste management 4 hours Practical 20 hours Compound Microscope. Demonstration and sterlization of equipments - Hot Air oven, Autoclave, Bacterial filters. Demonstration of commonly used culture media, Nutrient broth, Nutrient agar, Blood agar, Chacolate agar, Mac conkey medium, LJ media, Robertson Cooked meat media, Potassium Tellurite media with growth, Mac with LF & NLF, NA with staph Antibiotic susceptibility test Demonstration of common serological tests - Widal, VRDL, ELISA. Grams stain Acid fast staining Stool exam for Helminthic ova Visit to hospital for demonstration of biomedical waste mangement. Anaerobic culture methods. Internal Assessment Theory - Average of two exams conducted. 20 Practicals: Record & Lab work* 10 * There shall be no University Practical Examination and internal assessment marks secured in Practicals need not be sent to the University. Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 80 marks. Distribution of type of questions and marks for Microbiology shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20
  • 25. 24 SHORT ESSAY (SE) 6 6 x 5 30 SHORT ANSWER (SA) 10 10 x 3 30 TOTAL MARKS 80 NO PRACTICAL EXAMINATION REFERENCE BOOKS Microbiology 1. Anathanarayana & Panikar Medical Microbiology 2. Roberty Cruckshank - Medical Microbiology - The Practice of Medical Mircrobiology 3. Chatterjee - Parasitology - Interpretation to Clinical medicine. 4. Rippon - Medical Mycology 5. Emmons - Medical mycology 6. Basic laboratory methods in Parasitology, 1st Ed, J P Bros, New Delhi - 199 7. Basic laboratory procedures in clinical bacteriology, 1st Ed, J P Brothers, New Delhi. II YEAR BSc DEGREE PERFUSION TECHNOLOGY SYLLABUS APPLIED PHARMACOLOGY • General concepts about pharmacodynamic and Pharmacokinetic Principles involved in drug activity. I. Autonomic nerves system. • Anatomy & functional organisation. • List of drugs acting an ANS including dose, route of administration, indications, contra indications and adverse effects. II. Cardiovascular drugs- Enumerate the mode of action, side effects and therapeutic uses of the following drugs.
  • 26. 25 a. Antihypertensives • Beta Adrenergic antagonists • Alpha Adrenergic antagonists • Peripheral Vasodilators • Calcium channel blockers b. Antiarrhythmic drugs c. Cardiac glycosides d. Sympathetic and nonsympathetic inotropic agents. e. Coronary vasodilators. f. Antianginal and anti failure agents g. Lipid lowering & anti atherosclerotic drugs. h. Drugs used in Haemostais - anticoagulants Thrombolytics and antithrombolytics. i. Cardioplegic drugs- History, Principles and types of cardioplagia. j. Primary solutions - History, principles & types. k. Drugs used in the treatment of shock. III. Anaesthetic agents. • Definition of general and local anaesthetics. • Classification of general anaesthetics. • Pharmacokinetics and Pharmacodynamics of inhaled anaesthetic agents. • Intravenous general anaesthetic agents. • Local anaesthetics - classification mechanism of action, duration of action and methods to prolong the duration of action. Preparation, dose and routes of administration. IV. Analgessics • Definition and classification• Routes of administration, dose, frequency of administration, Side effects and management of non opioid and opiod analgesics V. Antihistamines and antiemetics-• Classification, Mechanism of action, adverse effects, Preparations, dose and routes and administration. VI. CNS stimulants and depressants • Alcohol • Sedatives, hypnotics and narcotics • CNS stimulants
  • 27. 26 • Neuromuscular blocking agents and muscle relaxants. VII. Pharmacological protection of organs during CPB VIII. Inhalational gases and emergency drugs. IX. Pharmacotherapy of respiratory disorders • Introduction - Modulators of bronchial smooth muscle tone and pulmonary vascular smooth muscle tone • Pharmacotherapy of bronchial asthma • Pharmacotherapy of cough • Mucokinetic and mucolytic agents • Use of bland aerosols in respiratory care. X. Corticosteroids - Classification, mechanism of action, adverse effects and complications.Preparation, dose and routes of administration. XI. Diuretics • Renal physiology • Side of action of diuretics • Adverse effects • Preparations, dose and routes of administrion. XII. Chemotherapy of infections • Definition • Classification and mechanism of action of antimicrobial agents • Combination of antimicrobial agents • Chemoperophylaxis. • Classification, spectrum of activity, dose, routes of administration and adverse effects of penicillin, cephalosporins, aminoglycosides, tetracyclines, chloramphenicol, antitubercular drugs. XIII.Miscellaneous. • IV fluids- various preparations and their usage. • Electrolyte supplements • Immunosuppressive agents • New drugs included in perfusion technology. • Drugs used in metabolic and electrolyte imbalance.
  • 28. 27 PRACTICALS: 1. Preparation and prescription of drugs of relevance. 2. Experimental pharmacology directed to show the effects of commonly used drugs of relevance and Interpretation of few charts. Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 80 marks. Distribution of type of questions and marks for applied Pharmacology shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 6 6 x 5 30 SHORT ANSWER (SA) 10 10 x 3 30 TOTAL MARKS 80 NO PRACTICAL EXAMINATION Recommended Books. 1. R. S. Satoskar, S.D. Bhandarkar, S. S. Ainapure, Pharmacology and Pharmacotherapeutics, 18th Edition, single Volume, M/S Popular Prakashan, 350, Madan Mohan Marg, Tardeo,Bombay - 400 034. 2. K.D. Tripathi, Essentials of Medical Pharmacology, V. Edition, M/s. Jaypee Brothers 3. Laurence and Bennet, Clinical Pharmacology, ELBS Edition, 9th Edition. APPLIED PATHOLOGY I. CARDIOVASCULAR SYSTEM
  • 29. 28 • Atherosclerosis- Definition, risk factors, briefly Pathogenesis & morphology, clinical significance and prevention. • Hypertension- Definition, types and briefly Pathogenesis and effects of Hypertension • Aneurysms - Definition, classification, Pathology and complications. • Pathophysiology of Heart failure • Cardiac hypertrophy - causes, Pathophysiology & Progression to Heart Failure • Ischaemic heart diseases- Definition, Types. Briefly Pathophysiology, Pathology & Complications of IHD • Valvular Heart diseases- causes, Pathology & complication. Complications of artificialHeart valves. • Cardiomyopathy - Definition, Types, causes and significance • Pericardial effusion- causes, effects and diagnosis • Congenital heart diseases - Basic defect and effects of important types of congenital heart diseases. II. HAEMATOLOGY • Anaemia - Definition, morphological types and diagnosis of anaemia.Brief concept about Haemolytic anaemia and polycythaemia. • Leukocyte disorders- Briefly leukaemia, leukocytosis, agranulocytosis etc. • Bleeding disorders- Definition, classification, causes & effects of important types of bleeding disorders. Briefly various laboratory tests used to diagnose bleeding disorders. III. RESPIRATORY SYSTEM • Chronic obstructive airway diseases - Definition and types. Briefly causes, Pathology and complications of each type of COPD. • Briefly concept about obstructive versus restrictive pulmonary disease. • Pneumoconiosis- Definition, types, Pathology and effects in brief. • Pulmonary congestion and edema. • Pleural effusion - causes, effects and diagnosis. IV. RENAL SYSTEM • Clinical manifestations of renal diseases. Briefly causes, mechanism, effects and lab diagnosis of ARF & CRS. Briefly Glomerulonephritis and Pyelonephritis.
  • 30. 29 • End stage renal disease - Definition, causes, effects and role of dialysis and renal transplantation in its management. • Brief concept about obstructive uropathy. PRACTICALS 1. Description & diagnosis of the following gross specimens. a. Atherosclerosis- b. Aortic aneurysm.- c. Myocardial infraction.- d. Emphysema- e. Chronic glomerulonephritis. f. Chronic pyelonephritis. 2. Interpretation & diagnosis of the following charts. a. hematology Chart - AML, CML, Hemophilia, neutrophilia, eosinophilia.- b. Urine Chart - ARF, CRF, AGN 3. Estimation of Hemoglobin. 4. Estimation Bleeding & Clotting time. Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 50 marks. Distribution of type of questions and marks for Applied Pathology shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 3 3 x 5 15 SHORT ANSWER (SA) 5 5 x 2 15 TOTAL MARKS 50
  • 31. 30 PRACTICAL EXAMINATION 40 Marks. There will be a Combined Practical examination for Applied Pathology & Applied Microbiology. Sl. No. Tests Marks 01 Interpretation of Hematology Chart 05 02 Interpretation of Urine Chart 05 03 Estimation of Hemoglobin 05 04 Estimation of Bleeding time & Clotting time 05 Total 20 APPLIED MICROBIOLOGY THEORY - 40 HOURS 1. Health care associated infections and Antimicrobial resistance: Infections that patients acquire during the course of receiving treatment for other conditions within a healthcare setting like Methicillin Resistant Staphylococcus aureus infections, Infections caused by Clostriduium difficle, Vancomycin resistant enterococci etc. Catheter related blood stream infections, Ventilator associated pneumonia, Catheter Related urinary tract infections, Surveillance of emerging resistance and changing flora. The impact and cost attributed to Hospital Associated infection. 6 Hours 2. Disease communicable to Healthcare workers in hospital set up and its preventive measure: Occupationally acquired infections in healthcare professionals by respiratory route (tuberculosis, varicella-zoster, respiratory synctial virus etc), blood borne transmission (HIV, Hepatitis B, C, Cytomegalovirus, Ebola virus etc), oro faecal route (Salmonella, Hepatitis A
  • 32. 31 etc), direct contact (Herpes Simplex Virus etc). Preventive measures to combat the spread of theseinfections by monitoring and control. 6 Hours 3. Microbiological surveillance and sampling: Required to determine the frequency of potential bacterial pathogens including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis and also to assess the antimicrobial resistance.Sampling: rinse technique, direct surface agar plating technique. 6 Hours 4. Importance of sterilization: a. Disinfection of instruments used in patient care: Classification, different methods, advantages and disadvantages of the various methods. b. Disinfection of the patient care unit c. Infection control measures for ICU's 10 Hours
  • 33. 32 5. Sterilization: a. Rooms: Gaseous sterilization, one atmosphere uniform glow discharge plasma (OAUGDP). b. Equipments: classification of the instruments and appropriate methods of sterilization. c. Central supply department: the four areas and the floor plan for instrument cleaning, high-level disinfecting and sterilizing areas. 8 Hours 6. Preparation of materials for autoclaving: Packing of different types of materials, loading, holding time and unloading. 4 Hours PRACTICALS- 30 HOURS 1. Principles of autoclaving & quality control of Sterilization. 2. Collection of specimen from outpatient units, inpatient units, minor operation theater and major operation theater for sterility testing. 3. The various methods employed for sterility testing. 4. Interpretation of results of sterility testing. 5. Disinfection of wards, OT and Laboratory. Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 50 marks. Distribution of type of questions and marks for Applied Microbiology shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 4 4 x 5 20 SHORT ANSWER (SA) 5 5 x 2 10 TOTAL MARKS 50
  • 34. 33 PRACTICAL EXAMINATION 40 Marks There will be a Combined Practical examination for Applied Pathology & Applied Microbiology. No. Tests Marks 01 Dry heat / Moist heat: Temperature recording-charts interpretation 05 02 Dry heat / Moist heat: Colour change-indicators interpretation 05 03 Air sampling culture plates interpretation of Colony forming units based on air flow rate and sampling time 05 04 Interpretation of Sterility of Haemodialysis water/Distilled water /Deionised water based on growth of colonies in BHI agar to be reported as X CFU/mL 05 Total 20 INTRODUCTION TO PERFUSION TECHNOLOGY Basics of diagnostic techniques: o Chest of X-ray-ECG-Echo-Angiography o Nuclear Cardiology o Laboratory investigations in relation to perfusion technology o Cardiopulmonary bypass and perfusion technology o History of Cardiac surgery and perfusion-Specific reference of Gibbon Lillehei, carrel • Pre CPB surgery • Azygous Flow principle. • Hypothermic/nonhypothermic non-CPB surgery including gross's Well technique and controlled cross circulation. Monitoring and instrumentation • Concepts of monitoring - instrumentation technology of ECG machine, pressure transducer, syringe and peristaltic pumps, monitors, ventilators, pulse oximeters, temperature probes and thermo regulatory monitoring, defibrillators and fibrillators. Piped
  • 35. 34 and non-piped gas delivery systems and connections. Basic physics related to medically used gases. • Haemodynamic monitoring• Haemostatic monitoring• Haemotologic monitoring • Maintenance of oxygen, carbon dioxide and acid-base status and their monitoring • Neurological monitoring (SSPE, EEG and cerebral function monitor) • Aseptic technique. • Cardiac surgery team, profession and terminology, scope of perfusion technology Physiology of Extracorporeal circulation Heart - Lung machine • Principles of extracorporeal circulation• Materials used in EC circuit •Principles of extracorporeal gas exchange 47Various types of oxygenators • Bubble oxygenators• Rotating spiral/cylinder/disc oxygenators • Membrane oxygenators • Mechanism of action components defoaming, rated flow. Theory of blood pumps • Ideal blood pump, pulsatile versus non-pulsatile flow, occlusive and non-occlusive pumps, various types of pumps roller, bellow, sigmamotor, diaphragm, ventricular and centrifugal pumps. Element of extracorporeal circulation/hazards of: a. Blood failure b. Bubble trap c. Flow meters d. Temperatures e. Heat exchanger f. Regulating devices Connection of the vascular system with extracorporeal circulation: • Arterial and venous cannulae. • Connecting tubes and connectors • Vents • Suckers • Cardioplegia delivery system
  • 36. 35 • Venous drainage. Haemodynamic of arterial return, venous drainage, cardioplegia Delivery and venting. Blood banking, handling of blood products and their management. Blood components and their use. Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 100 marks. Distribution of type of questions and marks for Introduction to Perfusion Technology shall be as given under TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 12 12 x 5 60 SHORT ANSWER (SA) 10 10 x 2 20 TOTAL MARKS 100 PRACTICAL EXAMINATION 40 Marks III YEAR B.Sc PERFUSION TECHNOLOGY Paper-I Perfusion Technology Clinical 1. Pharmacokinetics and Pharmacodynamics of Cardiopulmonary bypass 2. Drugs (including anesthetic drugs) used in cardiopulmonary bypass 3. Conduct and monitoring of Cardiopulmonary bypass 4. Adequacy of perfusion - General considerations, specific aspects of perfusion, monitoring, other concomitants which may affect its adequacy 5. Pulsatile perfusion - Introduction, theory & physiology of pulsatile flow, hemodynamic, metabolic Effects, Clinical use, hematological effects 6. Cannulation techniques during cardaiopulmonary bypass 7. Termination of cardiopulmonary bypass - principles and methodology 8. Myocardial protection and cardioplegia- pretreatment of the Myocardium,cardioplegia, hypothermia, controlled reperfusion, myocardial protection for specific clinical problems,Complications of cardioplegia. Non cardioplegic methods during cardiac surgery on cardiopulmonary bypass
  • 37. 36 9. Oxygenation - general consideration, bubble & membrane (including assessment and comparison of oxygenator function) 10. Heat exchangers-principles function of heat exchangers & their assessment. Complications related to heat exchange and their management 11. Priming fluids and hemodilution Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 100 marks. Distribution of type of questions and marks for Paper-I - Perfusion Technology - Clinical shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 12 12 x 5 60 SHORT ANSWER (SA) 10 10 x 2 20 TOTAL MARKS 100 PRACTICAL EXAMINATION One common practical for all the three papers with equal weight age of marks i.e. 40 practical marks for each paper. III YEAR B.Sc PERFUSION TECHNOLOGY Paper-II Perfusion Technology – Applied 1. Blood cell trauma - analysis of forces of fluid motion, effects of physical forces o blood cell, clinical effect. Complications of blood transfusion. 2. Anticoagulation on bypass, its monitoring, its reversal and complications. Heparin less bypass. Platelet aggregation and platelet dysfunction. Coagulopathies due to cardiopulmonary bypass and its management.
  • 38. 37 3. Inflammatory response to cardiopulmonary bypass & its clinical effects. Methods to minimize the same. Immune response, neuroendocrine, renal, metabolic splanchnic response, pulmonary response and electrolyte response to cardiopulmonary bypass 4. Blood conservation hemofiltration & dialysis during cardiopulmonary bypass including modified ultra-filtration reverse autologous priming and other methods 5. Micro emboli- gaseous and particulate, filters used in cardiopulmonary bypass circuit. 6. Micro pore filtration during cardiopulmonary bypass 7. Counter pulsation techniques and assist devices Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 100 marks. Distribution of type of questions and marks for Paper-II - Perfusion Technology Applied shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 12 12 x 5 60 SHORT ANSWER (SA) 10 10 x 2 20 TOTAL MARKS 100
  • 39. 38 PRACTICAL EXAMINATION One common practical for all the three papers with equal weight age of marks i.e. 40 practical marks for each paper. III YEAR B.Sc PERFUSION TECHNOLOGY Paper-III Perfusion Technology - Advanced 1. Perfusion techniques for Paediatric cardiac surgery 2. ECMO- special perfusion techniques for special cardiac surgeries and medical conditions (Including thoracic aortic surgeries deep hypothermia and circulatory arrest). Perfusion for non cardiac surgery, invasive cardiology and outside the operation suite. 3. Perfusion as a method of cardiopulmonary bypass 4. Complications and safety during cardiopulmonary bypass - bypass safety, organizational aspects, accidents, coagulpathies, mechanical and electrical failures, perfusion management, perfusion systems, safety for the perfusionist and surgical team management of perfusion accidents. 5. Minimally invasive surgery and the perfusionist 6. Recent advances in perfusion techniques 7. Experimental perfusion Scheme of Examination Theory There shall be one theory paper of three hours duration carrying 100 marks. Distribution of type of questions and marks for Paper-III - Perfusion Technology Advanced shall be as given under. TYPE OF QUESTION NUMBER OF QUESTIONS MARKS SUB-TOTAL LONG ESSAY (LE) 2 2 x 10 20 SHORT ESSAY (SE) 12 12 x 5 60 SHORT ANSWER (SA) 10 10 x 2 20 TOTAL MARKS 100
  • 40. 39 PRACTICAL EXAMINATION One common practical for all the three papers with equal weight age of marks i.e. 40 practical Marks for each paper 2.11 No: of hours per subject As given under clause “Content of each subject in each year “ 2.12 Practical training As given under clause “Content of each subject in each year “ 2.13 Records To be maintained for all Practical Work and duly signed by the supervising teacher should be submitted at the time of University practical examination 2.14 Dissertation: Not Applicable 2.15 Speciality training if any Cardiology, Nephrology, Blood Bank, Sterilization Room, Anesthesia etc according to the facility. 2.16 Project work to be done if any Not Applicable 2.17 Any other requirements [CME, Paper Publishing etc.] As per direction of HOD 2.18 Prescribed/recommended textbooks for each subject Anatomy- Chaursia Physiology-Chembulingam Biochemistry-Vasudevan
  • 41. 40 Microbiology- Ananthanarayanan Pathology-Harsh Mohan Pharmacology-Tripathi Medicine- Davidson Perfusion Technology- Gravlee 2.19 Reference books Anatomy 1 William Davis (P) understanding Human Anatomy and Physiology MC Graw Hill 2. Chaursia –A Text book of Anatomy T.S. Ranganathan – A text book of Human Anatomy 3.Fattana, Human anhiatomy (Description and applied) Saunder’s & C P Prism Publishers, Bangalore – 1991 4. ESTER. M. Grishcimer, Physiology & Anatomy with Practical Considerations, J.P. Lippin Cott. Philadelphia 5.Essential of Human embryology, Bhatnagar revised edition, Orient Longman PVT L t d . Physiology 1. Guyton (Arthur) Text Book of Physiology. Latest Ed. Prism publishers 2. Chatterjee(CC) Human Physiology Latest Ed. Vol-1, Medical Allied Agency 3. Choudhari (Sujith K) Concise Medical Physiology Latest Ed. New Central Book, 4. Ganong (William F) Review of Medical Physiology. Latest Ed. Appleton Biochemistry 1. Varley – Clinical chemistry 1.TEITZ – Clinical chemistry 2.Kaplan – Clinical chemistry-Ramakrishna(S) Prasanna(KG), Rajna ® Text book of Medical Biochemistry Latest Ed Orient longman Bombay –1980 3.Vasudevan (DM) Sreekumari(S) Text book of Biochemistry for Medical students ,Latest Ed
  • 42. 41 4.DAS(Debajyothi) Biochemistry Latest ED Academic, Publishers, Culcutta 5.Text Book of Medical Biochemistry – 3rd Edition, Orient Longman PVT Ltd 6.Practical Biochemistry for Medical Students – Rajagopal, Orient Longman PVT Ltd Pathology 1. Culling Histopathology techniques 2.Bancroft Histopathology techniques 3.Koss – cytology 4.Winifred greg – Diagnostic cytopathology 5.Orell – Cyto Pathology 6.Todd & Sanford Clinical Diagnosis by laboratory method 7.Dacie & Lewis – Practical Haematology 8.Ramanic Sood, Laboratory Technology (Methods and interpretation) 4th Ed. J.P. Bros, New Delhi –1996) 9.Satish Gupta Short text book of Medical Laboratory for technician J.P. Bros, New Delhi – 1998 10.Sachdev K.N. Clinical Pathology and Bacteriology 8th Ed, J.P. Bros, New Delhi-1991. 10. Krishna - Text book of Pathology, Orient Longman PVT Ltd. Bacteriology 8th Ed, J.P. Microbiology 1.Anathanarayana & Panikar Medical Microbioloty 2.Roberty Cruckshank – Medical Microbiology – The Practice of Medical Mircrobiology 3.Chatterjee – Parasitology – Interpretation to Clinical medicine. 4.Rippon – Medical Mycology 5.Emmons – Medical mycology 6.Basic laboratory methods in Parasitology, 1st Ed, J P Bros, New Delhi – 199 7.Basic laboratory procedures in clinical bacteriology, 1st Ed, J P Brothers, New Delhi 2nd year Syllabus APPLIED PHARMACOLOGY Recommended Books.
  • 43. 42 1. R. S. Satoskar, S.D. Bhandarkar, S. S. Ainapure, Pharmacology and Pharmacotherapeutics, 18th Edition, single Volume, M/S Popular Prakashan,350, Madan Mohan Marg, Tardeo, Bombay – 400 034. 2. K.D. Tripathi, Essentials of Medical Pharmacology, V. Edition, M/s. Jaypee Brothers, Post Box, 7193, G-16, EMCA House, 23/23, Bansari Road, Daryaganj, New Delhi. 3. Laurence and Bennet, Clinical Pharmacology, ELBS Edition, 9th Edition 2.20 Journals 1. Annals of Thoracic surgery 2. Journal of Indian association of Perfusions 3. Journal of American Society of Extra corporeal Technicians 4. IACTS journal 2.21 Log book To be maintained for all academic work which shall be counter signed by concerned HOD