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ALVEOLAR BONE

                1
Part I

BONE




          2
BONE TISSUE
   Bone tissue                               2 Types of bone tissue:
       is a specialized form of          1.      Compact (Cortical) bone
        connective tissue and is
        the main element of the           2.      Spongy (Cancellous) bone
        skeletal tissues.
       is composed of cells and
        an extracellular matrix in
        which fibers are
        embedded.
       is unlike other
        connective tissues in that
        the extracellular matrix
        becomes calcified.


                           http://en.wikipedia.org/wiki/Bone_tissue
                                                                             3
http://en.wikipedia.org/wiki/Haematopoiesis




FUNCTIONS OF BONE
1.   Support: provides framework that supports and anchors
     all soft organs.

2.   Protection: skull and vertebrae surround soft tissue of the
     nervous system, and the rib cage protects vital thoracic
     organs.

3.   Movement: skeletal muscles use the bones as levers to
     move the body.

4.   Storage: fat stored in the interior of the bones. Bone
     matrix serves as a storehouse for various minerals.

5.   Blood Cell Formation: hematopoiesis occurs within the
     marrow cavities of the bones.
                                                                         4
CLASSIFICATION OF BONE
   Bone may be classified in several ways:

      Developmentally          Histologically          By shape
    Endochondral bone      Compact (Cortical)    Long bones
                           Bone
    Intramembranous bone   Spongy (Cancellous)   Short bones
                           Bone
                                                 Flat bones
                                                 Irregular bones




                                                                   5
A.       endochondral bone
 •        Where bone is preceded by a cartilagenous model that
          is eventually replaced by bone In a process termed
          endochondral ossification.


B.       intramembranous bone
     •     Where bone forms directly w/in a vascular, fibrous
           membrane.




                                                                 6
“Oral Anatomy, Histology, and Embryology”




CHEMICAL PROPERTIES OF BONE
   60 % Inorganic
    material                                        Composition of bones
       is formed from
        carbonated
        hydroxyapatite.
                                                                           Inorganic
                                                                           Substances
   25 % Organic                                                           Organic
    material                                                               Substances
       mainly composed of                                                 Water
        Type I collagen.
       The organic part is
        also composed of
        various growth
        factors:                                       15% Water
            glycosaminoglycans,
             osteocalcin,
             osteonectin, bone
             sialo protein,
             osteopontin and Cell                                                       7
ORGANIC MATRIX OF THE BONE
   Bone is formed by the   Organic Components of the
    hardening of the               Bone Matrix
    matrix, entrapping the
    cells. When these cells                    Collagen
    become entrapped from
    osteoblasts they become                    Non-
    osteocytes.                                collagenous
                                                 proteins

   The organic matrix of bone
    is about:
       90% collagen
       10% non-collagenous
        proteins.

                                                            8
   Non-collagenous Proteins of Bone
     are a heterogeneous group which vary from
      entrapped serum protein to glycoproteins
     play a role in mineralization.

     The main non-collagenous proteins comprise
      the:
       Proteoglycans

       Glycoproteins

       Bone Gla-containing proteins
       Serum proteins

                                               9
   collagen.
     Contributes   towards the important biomechanical
      properties of tissue in terms of resisting loads
      and providing necessary resilience that prevents
      fractures.
     The dominant collagen in bone is Type I.
     Intrinsic collagen
        collagen   as secreted by osteoblasts.
     Extrinsic   collagen
        Collagen   formed by adjacent fibroblasts.

                                                      10
SHARPEY’S FIBERS
   Sharpey's fibers are the
    terminal ends of principal
    fibers (of the periodontal
    ligament) that insert into the
    cementum and into the
    periosteum of the alveolar
    bone.
   A study on rats suggests that
    the three-dimensional
    structure of Sharpey's fibers
    intensifies the continuity
    between the periodontal
    ligament fiber and the alveolar
    bone (tooth socket), and acts
    as a buffer medium against
    stress.

                                      11
CELL TYPES IN BONE
   Osteoblasts
       are mononucleate cells that are responsible for bone formation
   Osteocytes
       When osteoblasts become trapped in the matrix they secrete, they
        become osteocytes.
   Bone-lining cells
       Are inactive osteoblasts that cover all of the available bone surface
        and function as a barrier for certain ions
   Osteoprogenitor cells
       relatively undifferentiated cells found on or near all of the free
        surfaces of bone, which, under certain circumstances, undergo
        division and transform into osteoblasts or coalesce to give rise to
        osteoclasts.
   Osteoclasts
       is a type of bone cell that removes bone tissue by removing its
        mineralized matrix and breaking up the organic bone

                                                                                12
RESORPTION AND FORMATION OF BONE DURING
REMODELLING
 Resorption
 Reversal

 Formation

 Resting




                                          13
http://en.wikipedia.org/wiki/Ossification




OSSIFICATION
 Also called Osteogenesis
 is the natural process of bone formation
 There are two processes resulting in the
  formation of normal, healthy bone tissue:
       Endochondral (Intracartilaginous) Bone
        Ossification
          The formation of bone in which a cartilage template is
          gradually replaced by a bone matrix, as in the formation of
          long bones or in osteoarthritic ossification of synovial
          cartilage.
       Intramembranous Bone Ossification
          thedevelopment of bone from tissue or membrane, as in
          the formation of the skull.

                                                                        14
   Sutural Bone Growth
     variable
             and irregularly shaped bones in the
     sutures between the bones of the skull.




                                                   15
ALVEOLAR BONE
http://www.answers.com/topic/alveolar-bone#ixzz12ko9kyTQ




ALVEOLAR BONE
   Also called as alveolar
    process
   The specialized bone
    structure that contains the
    alveoli or sockets of the
    teeth and supports the
    teeth.

   If the teeth are lost the
    alveolar process disappears


   It is composed mainly of two
    parts:
       alveolar bone proper
       Supporting bone
Alveolar Bone
DEVELOPMENT OF ALVEOLAR BONE
DEVELOPMENT OF ALVEOLAR BONE

   Alveolar bone develops
    from the dental follicle


   The        ectomesenchymal
    cells of the dental follicle
    differentiate            into
    osteoblasts and lay down
    the matrix called osteoid


   Some osteoblasts become
    embedded in the matrix
    and are called osteocytes
Near the end of the 2nd
month of fetal life, mandible
and maxilla form a groove
that is opened toward the
surface of the oral cavity

As tooth germs start to
develop, bony septa form
gradually. The alveolar
process starts developing
strictly during tooth eruption.
GROSS MORPHOLOGY OF BONE

Morphology -is a branch of bioscience dealing with the study of the form
                 and structure of organisms and their specific structural
   Alveolar Socket
     Also called Dental
      alveolus
     are sockets in the
      jaws in which the
      roots of teeth are
      held in the alveolar
      process with the
      periodontal            Alveolar socket of the second
                             premolar tooth in a bovine
      ligament.              maxillary bone.
   Interdental Septa
     “Septa” – in Latin, it
      means “fence” or “wall”
     Are plates of bone that
      separate each
      individual sockets from
      one another.
   Interradicular Septa
       Are thin plates of bone
        that separate the roots
        of multi-rooted teeth
   Cribriform Plate
       also called as bundle
        bone
       Is the compact layer of
        bone lining the tooth
        socket (alveolar socket)
       Reflects the sieve-like
        appearance produced by
        numerous Volkmann’s
        canals passing from the
        alveolar bone to the PDL
        (periodontal ligament).
       Numerous Sharpey’s
        Fiber pass through it.
ALVEOLAR PROCESS
   is the thickened ridge of
    bone that contains the
    tooth sockets on bones
    that bear teeth.

   The alveolar process
    contains a region of
    compact bone adjacent
    to    the    periodontal
    ligament called Lamina
    dura.

   Maxilla and Mandible
       Are the   tooth-bearing
        bones
   Lamina Dura
     this part which is
      attached to the
      cementum of the roots
      by the periodontal
      ligament.
     Is the bone lining the
      alveolus
     In clinical
      radiographs, it                    Lamina Dura
      commonly appears as      Radiographic    appearance   of
                               alveolar bone proper as ‘Lamina
      a dense white line.      Dura’
FUNCTIONS OF THE BONE
FUNCTIONS OF ALVEOLAR BONE
   Protection
       Alveolar bone forms and protects the sockets for the teeth.

   Attachment
       It gives the attachment to the periodontal ligament fibers, which are
        the principle fibers. These fibers which enter the bone are regarded
        as Sharpey’s fibers.

   Support
       It supports the tooth roots on the facial and on the palatal/lingual
        sides.

   Shock-absorber
       It helps absorb the forces placed upon the tooth by disseminating the
        force to underlying tissues.
http://www.google.com.ph/imgres?q=cortical+plate+of+alveolar+bone&num=10&um=1&hl=tl&biw=1018&bih=414&tbm=isch&t
bnid=WKjYn2hOmQJweM%3A&imgrefurl=http%3A%2F%2Fwww.medicine.uiowa.edu%2Fanatomy%2Fdental%2Foralhist%2
                     FOHWIN%2Funit2%2F_ii-01.html&docid=VZHNS3piimFp2M&w=300&h=452&ei=x1WATpi2BoTBiQf3_-

STRUCTURE OF THE ALVEOLAR BONE
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                                                             64&start=0&ndsp=12&ved=1t%3A429%2Cr%3A0%2Cs%3A0




 Cortical Plate
 Spongiosa / Spongy
  Bone
a) outer cortical plates
b) a central spongiosa
c) bone lining the alveolus (bundle
bone)
CORTICAL PLATE
   Outer bony plate of varying
    thickness, which is the outside
    wall of the maxilla and
    mandible, covered with
    periosteum
   Continuous with the lamina
    cribriformis at the orifice of the
    alveoli – alveolar crest
   Consists of haversian systems
    (osteons) and interstitial
    lamellae
   Thicker in the mandible than
    maxilla
   Generally greater on the
    lingual than on the
    buccal/facial
ALVEOLAR BONE PROPER OR LAMINA
   An inner, heavily
    perforated bony
    lamellae, forming the
    alveolar wall
   In radiograph, appears
    as radioopaque line
    distinct from the adjacent
    spongiosa – Lamina
    Dura
   Contains osteons like
    other cortical bone, but
    is distinguished by the
    presence of Bundle
    Bone
SPONGIOSA
   Are spongy (or
    cancellous/trabecullar)
    bone between the 2 bony
    plates and between the
    lamina cribriformis of
    adjacent teeth or roots
   Consists of delicate
    trabeculae, between which
    are marrow spaces, filled
    mostly with fatty marrow
   Regions of maxillary
    tuberosity and the angle of
    mandible, erythropoietic …
VASCULAR SUPPLY OF ALVEOLAR BONE
VASCULAR SUPPLY OF ALVEOLAR PROCESS

   Alveolar process of the maxilla
     Anteriorand posterior alveolar arteries (branch
      from the maxilla and infraorbital arteries)
   Alveolar process of the mandible
     Inferioralveolar arteries (internal)
     Periosteal branches of submental and buccal
      arteries (external)
PERIODONTAL DISEASE
http://en.wikipedia.org/wiki/Periodontal_disease




PERIODONTAL DISEASE
   Periodontal disease is a
    type of disease that affects
    one or more of the
    periodontal tissues:
       Alveolar bone
       Periodontal ligament
       Cementum
       Gingiva
   While many different
    diseases affect the tooth-
    supporting
    structures, plaque-induced
    inflammatory lesions make
    up the vast majority of
    periodontal diseases and
    have traditionally been
    divided into two categories:
       gingivitis or
       periodontitis
HISTOLOGICAL ARRANGEMENT OF MATURE
BONE
        Mature bone is composed of:
         Compact bone
         Spongy Bone




                          http://www.physioweb.org/skeletal/bone_tissue.html
                                                                               40
41
http://en.wikipedia.org/wiki/Bone_tissue




COMPACT BONE
   Also called as Cortical bone
   As its name implies. . .
      “cortical” bone forms the cortex or outer shell of most bones.

      “compact” bone is much denser than cancellous bone.
        Furthermore, it is harder, stronger and stiffer than cancellous bone.
   The primary anatomical and functional unit of cortical bone is the
    osteon.
   3 Distinct Layering of Compact Bone:
      Circumferential lamella

      Concentric lamella

      Interstitial lamella

   Functions:
      facilitates to support the whole body

      protect organs

      provide levers for movement
                                                                                42
      store and release chemical elements, mainly calcium.
3 DISTINCT LAYERING OF COMPACT BONE:
    Circumferential Lamellae
        enclose the entire adult bone, forming its
         outer perimeter

    Concentric Lamellae
        make up the bulk of compact bone and form
         the basic metabolic unit of bone, the osteon

    Interstitial Lamellae
        interspersed between adjacent concentric
         lamellae and fill the spaces between them

                                                        43
44
SPONGY BONE
   Also called Cancellous bone or Trabecular bone
   Compared to compact bone, cancellous bone has a
    higher surface area but is less
    dense, softer, weaker, and less stiff.

   Cancellous bone is highly vascular and frequently
    contains red red bone marrow where hematopoeisis
    occurs.

   The primary anatomical and functional unit of
    cancellous bone is the trabecula.


                                                        45

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Bone

  • 3. BONE TISSUE  Bone tissue  2 Types of bone tissue:  is a specialized form of 1. Compact (Cortical) bone connective tissue and is the main element of the 2. Spongy (Cancellous) bone skeletal tissues.  is composed of cells and an extracellular matrix in which fibers are embedded.  is unlike other connective tissues in that the extracellular matrix becomes calcified. http://en.wikipedia.org/wiki/Bone_tissue 3
  • 4. http://en.wikipedia.org/wiki/Haematopoiesis FUNCTIONS OF BONE 1. Support: provides framework that supports and anchors all soft organs. 2. Protection: skull and vertebrae surround soft tissue of the nervous system, and the rib cage protects vital thoracic organs. 3. Movement: skeletal muscles use the bones as levers to move the body. 4. Storage: fat stored in the interior of the bones. Bone matrix serves as a storehouse for various minerals. 5. Blood Cell Formation: hematopoiesis occurs within the marrow cavities of the bones. 4
  • 5. CLASSIFICATION OF BONE  Bone may be classified in several ways: Developmentally Histologically By shape Endochondral bone Compact (Cortical) Long bones Bone Intramembranous bone Spongy (Cancellous) Short bones Bone Flat bones Irregular bones 5
  • 6. A. endochondral bone • Where bone is preceded by a cartilagenous model that is eventually replaced by bone In a process termed endochondral ossification. B. intramembranous bone • Where bone forms directly w/in a vascular, fibrous membrane. 6
  • 7. “Oral Anatomy, Histology, and Embryology” CHEMICAL PROPERTIES OF BONE  60 % Inorganic material Composition of bones  is formed from carbonated hydroxyapatite. Inorganic Substances  25 % Organic Organic material Substances  mainly composed of Water Type I collagen.  The organic part is also composed of various growth factors:  15% Water  glycosaminoglycans, osteocalcin, osteonectin, bone sialo protein, osteopontin and Cell 7
  • 8. ORGANIC MATRIX OF THE BONE  Bone is formed by the Organic Components of the hardening of the Bone Matrix matrix, entrapping the cells. When these cells Collagen become entrapped from osteoblasts they become Non- osteocytes. collagenous proteins  The organic matrix of bone is about:  90% collagen  10% non-collagenous proteins. 8
  • 9. Non-collagenous Proteins of Bone  are a heterogeneous group which vary from entrapped serum protein to glycoproteins  play a role in mineralization.  The main non-collagenous proteins comprise the:  Proteoglycans  Glycoproteins  Bone Gla-containing proteins  Serum proteins 9
  • 10. collagen.  Contributes towards the important biomechanical properties of tissue in terms of resisting loads and providing necessary resilience that prevents fractures.  The dominant collagen in bone is Type I.  Intrinsic collagen  collagen as secreted by osteoblasts.  Extrinsic collagen  Collagen formed by adjacent fibroblasts. 10
  • 11. SHARPEY’S FIBERS  Sharpey's fibers are the terminal ends of principal fibers (of the periodontal ligament) that insert into the cementum and into the periosteum of the alveolar bone.  A study on rats suggests that the three-dimensional structure of Sharpey's fibers intensifies the continuity between the periodontal ligament fiber and the alveolar bone (tooth socket), and acts as a buffer medium against stress. 11
  • 12. CELL TYPES IN BONE  Osteoblasts  are mononucleate cells that are responsible for bone formation  Osteocytes  When osteoblasts become trapped in the matrix they secrete, they become osteocytes.  Bone-lining cells  Are inactive osteoblasts that cover all of the available bone surface and function as a barrier for certain ions  Osteoprogenitor cells  relatively undifferentiated cells found on or near all of the free surfaces of bone, which, under certain circumstances, undergo division and transform into osteoblasts or coalesce to give rise to osteoclasts.  Osteoclasts  is a type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone 12
  • 13. RESORPTION AND FORMATION OF BONE DURING REMODELLING  Resorption  Reversal  Formation  Resting 13
  • 14. http://en.wikipedia.org/wiki/Ossification OSSIFICATION  Also called Osteogenesis  is the natural process of bone formation  There are two processes resulting in the formation of normal, healthy bone tissue:  Endochondral (Intracartilaginous) Bone Ossification  The formation of bone in which a cartilage template is gradually replaced by a bone matrix, as in the formation of long bones or in osteoarthritic ossification of synovial cartilage.  Intramembranous Bone Ossification  thedevelopment of bone from tissue or membrane, as in the formation of the skull. 14
  • 15. Sutural Bone Growth  variable and irregularly shaped bones in the sutures between the bones of the skull. 15
  • 17. http://www.answers.com/topic/alveolar-bone#ixzz12ko9kyTQ ALVEOLAR BONE  Also called as alveolar process  The specialized bone structure that contains the alveoli or sockets of the teeth and supports the teeth.  If the teeth are lost the alveolar process disappears  It is composed mainly of two parts:  alveolar bone proper  Supporting bone
  • 20. DEVELOPMENT OF ALVEOLAR BONE  Alveolar bone develops from the dental follicle  The ectomesenchymal cells of the dental follicle differentiate into osteoblasts and lay down the matrix called osteoid  Some osteoblasts become embedded in the matrix and are called osteocytes
  • 21. Near the end of the 2nd month of fetal life, mandible and maxilla form a groove that is opened toward the surface of the oral cavity As tooth germs start to develop, bony septa form gradually. The alveolar process starts developing strictly during tooth eruption.
  • 22. GROSS MORPHOLOGY OF BONE Morphology -is a branch of bioscience dealing with the study of the form and structure of organisms and their specific structural
  • 23.
  • 24. Alveolar Socket  Also called Dental alveolus  are sockets in the jaws in which the roots of teeth are held in the alveolar process with the periodontal Alveolar socket of the second premolar tooth in a bovine ligament. maxillary bone.
  • 25. Interdental Septa  “Septa” – in Latin, it means “fence” or “wall”  Are plates of bone that separate each individual sockets from one another.  Interradicular Septa  Are thin plates of bone that separate the roots of multi-rooted teeth
  • 26. Cribriform Plate  also called as bundle bone  Is the compact layer of bone lining the tooth socket (alveolar socket)  Reflects the sieve-like appearance produced by numerous Volkmann’s canals passing from the alveolar bone to the PDL (periodontal ligament).  Numerous Sharpey’s Fiber pass through it.
  • 27. ALVEOLAR PROCESS  is the thickened ridge of bone that contains the tooth sockets on bones that bear teeth.  The alveolar process contains a region of compact bone adjacent to the periodontal ligament called Lamina dura.  Maxilla and Mandible  Are the tooth-bearing bones
  • 28. Lamina Dura  this part which is attached to the cementum of the roots by the periodontal ligament.  Is the bone lining the alveolus  In clinical radiographs, it Lamina Dura commonly appears as Radiographic appearance of alveolar bone proper as ‘Lamina a dense white line. Dura’
  • 30. FUNCTIONS OF ALVEOLAR BONE  Protection  Alveolar bone forms and protects the sockets for the teeth.  Attachment  It gives the attachment to the periodontal ligament fibers, which are the principle fibers. These fibers which enter the bone are regarded as Sharpey’s fibers.  Support  It supports the tooth roots on the facial and on the palatal/lingual sides.  Shock-absorber  It helps absorb the forces placed upon the tooth by disseminating the force to underlying tissues.
  • 31. http://www.google.com.ph/imgres?q=cortical+plate+of+alveolar+bone&num=10&um=1&hl=tl&biw=1018&bih=414&tbm=isch&t bnid=WKjYn2hOmQJweM%3A&imgrefurl=http%3A%2F%2Fwww.medicine.uiowa.edu%2Fanatomy%2Fdental%2Foralhist%2 FOHWIN%2Funit2%2F_ii-01.html&docid=VZHNS3piimFp2M&w=300&h=452&ei=x1WATpi2BoTBiQf3_- STRUCTURE OF THE ALVEOLAR BONE W3Dg&zoom=1&iact=hc&vpx=89&vpy=48&dur=483&hovh=100&hovw=64&tx=101&ty=176&sqi=2&page=1&tbnh=100&tbnw= 64&start=0&ndsp=12&ved=1t%3A429%2Cr%3A0%2Cs%3A0  Cortical Plate  Spongiosa / Spongy Bone
  • 32. a) outer cortical plates b) a central spongiosa c) bone lining the alveolus (bundle bone)
  • 33. CORTICAL PLATE  Outer bony plate of varying thickness, which is the outside wall of the maxilla and mandible, covered with periosteum  Continuous with the lamina cribriformis at the orifice of the alveoli – alveolar crest  Consists of haversian systems (osteons) and interstitial lamellae  Thicker in the mandible than maxilla  Generally greater on the lingual than on the buccal/facial
  • 34. ALVEOLAR BONE PROPER OR LAMINA  An inner, heavily perforated bony lamellae, forming the alveolar wall  In radiograph, appears as radioopaque line distinct from the adjacent spongiosa – Lamina Dura  Contains osteons like other cortical bone, but is distinguished by the presence of Bundle Bone
  • 35. SPONGIOSA  Are spongy (or cancellous/trabecullar) bone between the 2 bony plates and between the lamina cribriformis of adjacent teeth or roots  Consists of delicate trabeculae, between which are marrow spaces, filled mostly with fatty marrow  Regions of maxillary tuberosity and the angle of mandible, erythropoietic …
  • 36. VASCULAR SUPPLY OF ALVEOLAR BONE
  • 37. VASCULAR SUPPLY OF ALVEOLAR PROCESS  Alveolar process of the maxilla  Anteriorand posterior alveolar arteries (branch from the maxilla and infraorbital arteries)  Alveolar process of the mandible  Inferioralveolar arteries (internal)  Periosteal branches of submental and buccal arteries (external)
  • 39. http://en.wikipedia.org/wiki/Periodontal_disease PERIODONTAL DISEASE  Periodontal disease is a type of disease that affects one or more of the periodontal tissues:  Alveolar bone  Periodontal ligament  Cementum  Gingiva  While many different diseases affect the tooth- supporting structures, plaque-induced inflammatory lesions make up the vast majority of periodontal diseases and have traditionally been divided into two categories:  gingivitis or  periodontitis
  • 40. HISTOLOGICAL ARRANGEMENT OF MATURE BONE  Mature bone is composed of:  Compact bone  Spongy Bone http://www.physioweb.org/skeletal/bone_tissue.html 40
  • 41. 41
  • 42. http://en.wikipedia.org/wiki/Bone_tissue COMPACT BONE  Also called as Cortical bone  As its name implies. . .  “cortical” bone forms the cortex or outer shell of most bones.  “compact” bone is much denser than cancellous bone. Furthermore, it is harder, stronger and stiffer than cancellous bone.  The primary anatomical and functional unit of cortical bone is the osteon.  3 Distinct Layering of Compact Bone:  Circumferential lamella  Concentric lamella  Interstitial lamella  Functions:  facilitates to support the whole body  protect organs  provide levers for movement 42  store and release chemical elements, mainly calcium.
  • 43. 3 DISTINCT LAYERING OF COMPACT BONE:  Circumferential Lamellae  enclose the entire adult bone, forming its outer perimeter  Concentric Lamellae  make up the bulk of compact bone and form the basic metabolic unit of bone, the osteon  Interstitial Lamellae  interspersed between adjacent concentric lamellae and fill the spaces between them 43
  • 44. 44
  • 45. SPONGY BONE  Also called Cancellous bone or Trabecular bone  Compared to compact bone, cancellous bone has a higher surface area but is less dense, softer, weaker, and less stiff.  Cancellous bone is highly vascular and frequently contains red red bone marrow where hematopoeisis occurs.  The primary anatomical and functional unit of cancellous bone is the trabecula. 45