SlideShare a Scribd company logo
1 of 74
Download to read offline
Age Reversal Update
Healthy Masters 2019
Portugal
William Faloon
age-reversal.net
This entire presentation and info
about our research available at:
“A triple drug
combination has been
used to extend the
lifespan of fruit flies by
48% in a new study.”
https://www.nextbigfuture.com/2019/10/rapamycin-and-two-other-drugs-extends-lifespan-twice-as-much-as-any-other-drug-combo.html
Rapamycin and Two Other Drugs Extends Lifespan
Twice As Much As Any Other Drug Combo
“Previousstudiesinfruitflieshave
achievedlifespan extensions ofabout
5-20%
…sowefounditwasquiteremarkable
thatthisdrugcombinationenabled
themtolive
Castillo-Quan, Jorge Iván, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Grönke, Yvonne
Hinze, T. Keith Blackwell, Ivana Bjedov, and Linda Partridge. "A triple drug combination
targeting components of the nutrient-sensing network maximizes longevity."
Proceedings of the National Academy of Sciences 116, no. 42 (2019): 20817-20819.
September 30, 2019
Combined Interventions More Effective than SingleAgent Therapy
PNAS October 15, 2019 116 (42) 20817-20819; first published September 30, 2019
https://doi.org/10.1073/pnas.1913212116
Rapamycin Lithium Dasatinib-like Drug+ +
Fruit Fly Lifespan Extension by 48%
=
“…a combination of drugs already approved for
human use is a viable strategy to maximize animal
longevity…”
This recent study supports the stairstep approach advocated to enable us to live significantly longer
September 30, 2019
Fruit flies received drugs separately and/or in combination.
 Each drug individually extended lifespan by 11%
 Pairing two drugs extended lifespan roughly 30%
 Three drugs combined extended lifespan by 48%
Castillo-Quan, Jorge Iván, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Grönke, Yvonne Hinze, T. Keith Blackwell, Ivana
Bjedov, and Linda Partridge. "A triple drug combination targeting components of the nutrient-sensing network
maximizes longevity." Proceedings of the National Academy of Sciences 116, no. 42 (2019): 20817-20819.
Combination Treatments are Essential
September 30, 2019
Interventions that may
improve your odds of
living to year 2030
…they are optimistic that a
person’s biological age can
be reversed.”
Age markers reversed by 2.5 years!
“ScientistsatInterveneImmuneandStanford
MedicalCenterhaveproventhat‘epigenetic
agingcanbereversedinhumans’...
Cocktail Of Drugs Gives First Hope
That ‘Biological Age’ Can Be Reversed
https://forbes.com/sites/robinseatonjefferson/2019/09/09/cocktail-of-drugs-gives-first-hope-that-biological-age-can-be-reversed/
“Reversal of epigenetic aging and immunosenescent trends in humans.” Aging Cell; Sept 2019
Combination Therapy also Effective in Humans
1) Human growth hormone
2) DHEA
3) Metformin
Study conducted by Dr. Greg Fahy in collaboration
with researchers from Stanford University and
UCLA consisted of individualized doses of:
Study subjects also provided with daily
vitamin D3 and zinc.
https://www.dailymail.co.uk/health/article-7435427/Aging-
REVERSED-small-group-men-study-reveals.htmll
Oct.22,2019Turning Back Time!
“Aging is REVERSED in
men using a cocktail of
growth hormones and
diabetes drugs in study
that saw test group shed
2.5 biological years.”
Type II diabetics taking metformin:
United Kingdom Diabetes Study
►32% reduced risk of diabetic complications
►42% reduced risk for diabetes-related death
►36% reduced all-cause mortality risk
Study Results Found in January 1995
British Medical Journal; Jan 14, 1995;” United Kingdom Prospective Diabetes Study (UKPDS)
Study Results Found on March 21st 2017
Journal of the American Medical Association
JAMA. Published online March 21, 2017. doi:10.1001/jama.2016.17844
Metformin studied in prediabetic patients. Compared
to placebo 850 mg of metformin two times a day:
Reduced type II diabetes risk 31%
In patients under age 60: metformin reduced diabetic risk by 58%.
“Metformin can cause weight loss…”Quote:
Sept. 2017
Metformin Demonstrates Therapeutic
Effects Against Colon Cancer
Am J Med Sci. 2017 Sep;354(3):246-251. doi: 10.1016/j.amjms.2017.05.006. Epub 2017 May 19.
Metformin Has Positive Therapeutic Effects in Colon Cancer and Lung Cancer.
Colon Cancer Metformin Patients Non-Metformin Patients
Recurrences 4% 19%
Metastases 23% 46%
5-Year Survival 57% 37%
Deaths 48% 76%
(Metformin boosts AMPK activity and indirectly inhibits mTOR)
Conclusion: “Metformin therapy is associated with significantly better prognosis in patients with colon cancer”
Caveat: Some diabetics in control group treated with insulin or sulfonylurea drugs that promote tumor cell propagation.
Diabetics on metformin showed these benefits compared to diabetics not prescribed metformin:
Diabetics taking metformin
have lower cancer rates
Metformin Prevents Cancer
MD Anderson Cancer Center found
risk of pancreatic cancer was 62%
lower in diabetics using metformin.
Li D, Yeung SC, Hassan MM, Konopleva M, Abbruzzese JL. Antidiabetic therapies
affect risk of pancreatic cancer. Gastroenterology. 2009 Aug;137(2):482-8.
Nov 29. 2015
Metformin Anti-aging Trial Gets Green-light
https://www.longevity.technology/worlds-first-anti-aging-trial-gets-green-light/
Sept 4, 2019
1958 - Metformin approved as anti-diabetic drug in England
1995 - Life Extension® lists metformin as anti-aging drug
2015 - FDA approves first anti-aging study of a drug (metformin)
2019 - Metformin study receives $75 million funding
($40 million from anonymous donor)
Life Extension recommended
metformin 24 years ago…
the FDA went berserk!
March 1995
Catastrophic Loss of Life
A 2019 study tabulated reductions in cardiovascular mortality in
type II diabetics using metformin.1
Life Extension® then calculated how many cardiovascular deaths
may have occurred in response to metformin’s 37-year delay.
Almost 4 million American diabetics may have died because of
the delay in this one drug (metformin) becoming available.
This exceeds the death toll of all wars America has ever fought.
1. Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular
Events Among Patients With Diabetes and Reduced Kidney Function. JAMA. 2019 September 19:1-11.
We Don’t Have Time for
Delayed Age Reversal
2019.12.08 Bill Faloon Healthy Masters Portugal
Statistically Significant + Meaningful
Age Reversal in 12 Months
Outcome Objectives:
$550,000 + donated/discounted services
Human Age Reversal Project
Vitality in Aging Interventions Trial
Study Cost:
Major Funding Provided by:
Fund research with tax deductible donations:
Human Age Reversal Project
Make checks payable to:
Human Age Reversal Project
300 NE 20th St. #409
Boca Raton, FL 33431
Or donate online:
age-reversal.net/donate
Age Reversal Interventions
1)Target 5 calorie restriction pathways
2) Reduce/resolve inflammation
3) Telomere lengthening
4) Selective remove senescent cells
5) Restore youthful methylation
age-reversal.net
VIA Interventions Trial
Price per Study
Subject:
ZERO
Estimated Value
per Study Subject:
>$10,000
Age Reversal
Interventions
Autophagy Resolve inflammation
Remove
senescent cells
Restore
youthful methylation
Lengthen
telomeres
AMPK/
mTOR
Sirtuins -
NAD+
Exosomes
Trial Parameters
> Open label (no placebo group)
> 50 healthy people aged 50-75 years
Initial Phase
Recruitment/Baseline Testing:
October 3rd 2019 – December 15th 2019
Vitality in Aging Intervention Trial
Vitality in Aging Interventions Trial
Timeline
Vitality in Aging Interventions Trial
Intervention #1
Calorie Restriction Mimetics
12% Calorie Reduction Improves Biological Age Scores by 1.5 Years
2018 Published Human study measures 8 Aging Biomarkers
Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis, J Gerontol A Biol Sci Med Sci. 2018 Jan; 73(1): 4-10.
Intervention:1 Targeting Calorie Restriction Pathways
Metformin
Metformin
Rapamycin, metformin
Pterostilbene, nicotinamide
Nicotinamide riboside
Rapamycin, glucosamine
Beta-lapachone
↓Insulin/IGF-1
↑AMPK
↓mTOR
↑Sirtuins
↑ NAD+
↑Autophagy
↑NAD/NADH ratio
VIA Interventions Trial
Increase
AMPK
Autophagy
Sirtuins/NAD+
Decrease
mTOR
Insulin
IGF-1 signals
Targets Calorie Restriction Pathways
Vitality in Aging Interventions Trial
Senolytics
Selective removal of senescent cells
Intervention #2
July 9, 2018
Magazine
“It’slooking like veryoldmice are able to substantially improve their health
span, reduce or delay age-related diseases and increase their survival.”
They calculated that if only one in 7,000 to 15,000 cells is senescent, then age-related
problems in physical function started to appear in the mice.
Like a contagion, senescent cells seem to pass on their accelerated aging abilities to healthy
cells by releasing a number of factors that can cause tissues like muscle to deteriorate.
Mice given senescent cells and the senolytic compounds lived 36% longer than animals
with senescent cell transplants who were not given the drugs.
How Scientists Are Testing
Cancer Drugs to Slow Down Aging
Drug to clear 'zombie cells' from body could be first
anti-aging treatment after ‘impressive’ human trial
https://www.telegraph.co.uk/science/2019/01/08/drug-clear-zombie-cells-body-could-first-anti-ageing-treatment/
Jan. 8, 2019
“A drug to fight aging may finally
be on the horizon after the
first trial in humans showed
‘impressive’ results.”
“The treatment clears out dead
cells even when the immune
system no longer can.”
This drug cocktail reduced signs of age-related
diseases and extended life in mice and human cells
Senolytic Delay May = Death
“Group led by Mayo Clinic anti-aging researcher James Kirkland not only offers a clear look at
the power of senescent cells to drive the aging process, but also a pharmaceutical cocktail that,
in mice at least, can slow and even reverse it.
Compared to mice who aged normally, those who started getting the dasatinib-quercetin cocktail at
an age equivalent to 75 to 90 years in humans ended up living roughly 36% longer, and with better
physical function.
In human cells in a test tube and in mice bearing human senescent cells, the dasatinib-quercetin
cocktail showed equally promising results, targeting senescent cells while leaving other cells intact.
Aging…is beginning to look more and more like a disease — and a treatable one at that.
ScientistsAre Testing
CancerDrugstoSlowDownAging July 10, 2019
SEPTEMBER 17, 2018
Scientific Discovery and the Future of Medicine
Journal of the American Medical Association
“…many human pathologic conditions are associated with the presence of
senescent cells.”
“Interventions aimed at eliminating those senescent cells, commonly called
senolytic, have also been shown to improve health and extend life in various
mouse disease models.
“If senolytics are shown to be safe and effective in humans, they could transform
care of older adults and patients with multiple chronic diseases.”
Reference: “Aging, Cell Senescence, and Chronic Disease:Emerging Therapeutic Strategies.”;
Journal of the American Medical Association (JAMA) September 17th 2018.
“Moreover, tremendous advances are being made in our
understanding of the science of aging, yielding exciting potential
treatments that may alter the course of this inevitable process.5 One
aspect of this work relates to “senolytics,” the study of ways to
either eliminate senescent cells that may have deleterious effects or
slow or reverse the aging process by restoring cells’ lost function.
“Enabling Healthful Aging for All —
The National Academy of Medicine Grand Challenge in Healthy Longevity”
https://www.nejm.org/doi/full/10.1056/NEJMp1912298?query=TOC
October 31, 2019
Purging failed brain insulation cells lessened damage,
improved cognition in Alzheimer's mouse model
Selective removal of senescent cells - Age-related accumulation
of senescent cells contributes to atherosclerosis, aging of the
eye (cataracts, AMD), osteoporosis, skin and brain aging,
Kirkland and colleagues at Mayo Clinic show that senescent cells
are selectively eliminated by “senolytic” drugs.
Senolytic Cocktail of:
Senolytics
1) Dasatinib
2) Quercetin
3) Fisetin
Suppress Chronic
Inflammation
Intervention #3:
1) Fish oil: Boost omega-3 index > 10%
Reduce and Resolve Chronic Inflammation
2) Resolvins: Return tissues to health
Inflammaging major cause of aging and contributes to the global
loss of Sirt1 function. We intend to use omega-3 fatty acids and
other fatty acids to increase resolvins, protectins, and maresins
with a target of a minimum of 10% omega-3 index.
Telomere
Elongation
Intervention #4:
Telomereshortening normally
occurs atarateof0.9%/year.
Telomere Lengthening
1) Exercise
2) Stress Control
3) Healthy Diet
4) Omega-3 fatty acids
Onesmallprospectivecontrolledstudyinolder
menshowedthattelomerescouldbelengthened
by2%peryearwithacombinationof:
Restoring
Youthful
Methylation
Intervention #5
“TheroleofDNA methylationin epigeneticsofaging”
 Epigenetics, especially DNA methylation,
plays a mechanistic role in aging.
 Epigenetic clocks are best biomarkers for
predicting human mortality.
 DNAmethylationinfluencedbymetformin,caloric
restriction and rapamycin treatment in mice.
 This may reverse/prevent 20% to 40% of the
age-related changes in DNA methylation.
Pharmacol Ther. 2019 March; 195:172-185. doi:10.1016/j.pharmthera.2018.11.001
Methods of Balancing Methylation
Pharmacol Ther. 2019 March; 195:172-185. doi:10.1016/j.pharmthera.2018.11.001
Metformin
CalorieRestrictionMimetics
Rapamycin
LS/tandemmassspectrometrybasedtesting
Quantitativeb-galactosidasestaining,p16INK4a,etc)
Neurovision – Mayo Clinic CD38
Johns Hopkins
Aging Biomarker Tests
Vitality in Aging Interventions Trial
More Accurate FlowFISH-
Based Telomere Length Tests
Newer DNA
Methylation Age Tests
NAD+, NAD/NADH ratio,
and NAD+ metabolite tests
Cell Senescence Tests
Univ of British Columbia/UCLA Galactosidasestaining,p16INK4a,skinpunch
NanoSomiX
Exosome tests for predicting
Alzheimer’s disease 10 years
prior to onset of memory loss
Age Management Panel
Comprehensive blood
biomarkers with Levine
Biological Age Calculator
Healthy Subjects in order to Measure Meaningful Age Reversal in 12 Months
Strict Inclusion Criteria for Study Subjects
Vitality in Aging Interventions Trial
Exercise
(10,000 step equivalent each day)
Healthy diet patterns
(no junk foods)
Restful sleep patterns
(no benzodiazepines)
Body Mass Index: 18-24
(no significant central fat mass)
No serious
preexisting disorders
No prescription narcotics
or recreational drugs
Target LDL below 80 mg/dl
Omega-3 Index > 8%
(achievablewithhighdosefishoil)
Long Term Funding Sources Will Be Needed
Human Age Reversal Project
Bill Faloon
Donations of Physicians’ Time
Funding Need: > $550,000
Donations Received to Date: >$625,000
20
Vitality In Aging Interventions Trial
SOURCES OF FUNDING:
New charity to fund research with tax deductible donations:
Human Age Reversal Project
Make checks payable to:
Human Age Reversal Project
300 NE 20th St. #409
Boca Raton, FL 33431
Or donate online:
age-reversal.net/donate
Omega-3 IndexLiver-Kidney Function
Cardiovascular
Inflammatory
Hormones
Lipids (full-spectrum)
NAD+
Glycemic Markers Blood Cell Counts
Vitamin D
Insulin Resistance
Growth Factors
NicotinamideFull ADPR
NAAD
ADPR
NAMN
NAD + metabolites PADPH
NAM
MeNAM
NADP+
age-reversal.net
This entire presentation available at:
Interventions that may
improve your odds of
living to year 2030
Lifespans
not limited by
senescence
Neocortex Connects-
Converts to the Cloud
Years 2030 2050
Stair Step Approach to Infinite Longevity
Singularity + A.I. enables
limitless self-improvement.
Hotel magnate Barron Hilton died
of natural causes at the age of 91.
He left about 97% of his estate to
Conrad N. Hilton Foundation, which
expects to grow its endowment
from $2.9 billion to $6.3 billion
www.foxbusiness.com/business-leaders/barron-hilton-fortune-estate-foundation
Who missed the longevity boat?
Barron Hilton (1927-2019)
Expiration date: Sept. 19, 2019
Net worth > $2.9 billion
Paris Hilton Barron Hilton
Too Wealthy to Die at Age 65
Paul Allen, Chairman of the Seattle
Seahawks co-founded Microsoft in 1975.
Diagnosed and treated for non-Hodgkin
lymphoma in 2009. Cancer returned in
2018. He died from septic shock.
Paul Allen was philanthropist and
donated to medical research…
but did NOT make it his priority!
https://www.nytimes.com/2018/10/15/obituaries/paul-allen-dead.html
Paul Allen (1953-2018)
Net worth > $26.1 billion
Expiration date: Oct. 15, 2018
Too Wealthy to Die at Age 58
Blake Nordstrom, company co-president,
dies unexpectedly at 58 from lymphoma.
At the time, he described his
condition as "treatable" and said he
planned to "continue to work
throughout this process as normal."
https://www.cnn.com/2019/01/02/business/blake-nordstrom-obit/
Blake Nordstrom(1961-2019)
Net worth > $1.5 billion
Expiration date: Jan. 2, 2019
Who Missed the Longevity Boat
Robert "Bob" McNair, billionaire
founder and owner of the
Houston Texans died at age 81.
He battled squamous cell
skin cancer and then
leukemia for about 20 years.
https://www.forbes.com/profile/robert-mcnair/#130c78d9251a
RobertMcNair (1937-2018)
Net worth ~ $3.8 billion
Expiration date: Nov. 23, 2018
Wealthy And Famous
That Expired In 2018
Who Missed the Longevity Boat
Herb Kelleher, the eccentric
founder of Southwest Airlines
who helped revolutionize
low-cost air travel in 1971.
Died at age 87.
https://www.cnn.com/2019/01/03/business/southwest-airlines-founder-herb-kelleher-obit
Herb Kelleher(1931-2019)
Net worth ~ $2.5 billion
Expiration date: Jan. 3, 2019
Wealthy And Famous
That Expired In 2019
“Just a year ago I felt
immortal, wearing my
age with pride, even
joking about it.”
https://www.nytimes.com/2019/09/11/business/boone-pickens-dead.html
Who missed the longevity boat?
T. Boone Pickens (1928-2018)
Expiration date: Sept. 11, 2019
Net worth > $950 million
In 2016 T. Boone Pickens wrote:
One year later suffered series of
strokes and a fall. Dead at age 91.
T. Boone Pickens Largely Funded $260 Million
Oklahoma State University Stadium
(He made many other charitable donations to biomedical research)
Fund research with tax deductible donations:
Human Age Reversal Project
Make checks payable to:
Human Age Reversal Project
300 NE 20th St. #409
Boca Raton, FL 33431
Or donate online:
age-reversal.net/donate
November,2009
No Human Age-Reversal
Intervention Identified
We Were Doomed 10 Years Ago
Huge Advances in Only 10 Years
No Way to Reverse Aging
Manhattan Beach Summit Attendees
November 2009
Many Potential Methods
2009 2019
2009-2019
Senolytics NAD+ Sirtuins mTOR-inhibition
AMPK
Activation
Umbilical Cord
Plasma/Blood
Exosomes from
Young Cells
Mesenchymal
Stem Cells
Immune
Restoration
Mitochondria
Restoration
Multiple Regenerative Interventions
age-reversal.net
This entire presentation available at:
2019.12.08 Bill Faloon Healthy Masters Portugal
2019.12.08 Bill Faloon Healthy Masters Portugal
Fund research with tax deductible donations:
Human Age Reversal Project
Make checks payable to:
Human Age Reversal Project
300 NE 20th St. #409
Boca Raton, FL 33431
Or donate online:
age-reversal.net/donate
http://med.miami.edu/news/interdisciplinary-stem-cell-institute-at-the-university-of-miami-receives-2
Interdisciplinary Stem Cell Institute
at the University of Miami Receives $25 Million Donation
“The Interdisciplinary Stem Cell Institute at
the University of Miami Miller School of
Medicine has received a $25 million
donation from the Soffer Family Foundation.”
“The funding will allow the institute to
continue its groundbreaking stem cell
research… in fields of cardiology, sports
medicine, and aging-related conditions.”
October 8th 2019
Unparalleled Track Record
of Biomedical Innovation
Established 1977
age-reversal.net
This entire presentation and info
about our research available at:
• END
2019.12.08 Bill Faloon Healthy Masters Portugal

More Related Content

What's hot

Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021
Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021
Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021maximuspeto
 
Clinical Trials Update by Bill Faloon at RAADfest 2021
Clinical Trials Update by Bill Faloon at RAADfest 2021Clinical Trials Update by Bill Faloon at RAADfest 2021
Clinical Trials Update by Bill Faloon at RAADfest 2021maximuspeto
 
Age Reversal Update from Bill Faloon on December 15th 2020
Age Reversal Update from Bill Faloon on December 15th 2020Age Reversal Update from Bill Faloon on December 15th 2020
Age Reversal Update from Bill Faloon on December 15th 2020maximuspeto
 
Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021maximuspeto
 
Bill Faloon gives update about human age-reversal clinical studies
Bill Faloon gives update about human age-reversal clinical studiesBill Faloon gives update about human age-reversal clinical studies
Bill Faloon gives update about human age-reversal clinical studiesmaximuspeto
 
Bill Faloon at DaVinci 50 about stroke risk and blood pressure
Bill Faloon at DaVinci 50 about stroke risk and blood pressureBill Faloon at DaVinci 50 about stroke risk and blood pressure
Bill Faloon at DaVinci 50 about stroke risk and blood pressuremaximuspeto
 
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021maximuspeto
 
Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021maximuspeto
 
Drug to slow down aging
Drug to slow down agingDrug to slow down aging
Drug to slow down agingOther Mother
 
William Faloon on Age Reversal
William Faloon on Age ReversalWilliam Faloon on Age Reversal
William Faloon on Age ReversalAlex Vidal
 
Does animal testing help human medicine
Does animal testing help human medicineDoes animal testing help human medicine
Does animal testing help human medicineAll Animal Rights
 
Supplements Cady At Oliver Seminar
Supplements    Cady At  Oliver SeminarSupplements    Cady At  Oliver Seminar
Supplements Cady At Oliver SeminarLouis Cady, MD
 
유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용
유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용
유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용Hyung Jin Choi
 
Moving from Big Data to Better Models of Disease and Drug Response - Joel Dudley
Moving from Big Data to Better Models of Disease and Drug Response - Joel DudleyMoving from Big Data to Better Models of Disease and Drug Response - Joel Dudley
Moving from Big Data to Better Models of Disease and Drug Response - Joel DudleyCityAge
 
Autologous Bone Marrow Cell Therapy for Autism: An Open Label Uncontrolled C...
Autologous Bone Marrow Cell Therapy for Autism: An  Open Label Uncontrolled C...Autologous Bone Marrow Cell Therapy for Autism: An  Open Label Uncontrolled C...
Autologous Bone Marrow Cell Therapy for Autism: An Open Label Uncontrolled C...remedypublications2
 
Targeting Biological Aging: A New Paradigm for 21st Century Medicine
Targeting Biological Aging: A New Paradigm for 21st Century MedicineTargeting Biological Aging: A New Paradigm for 21st Century Medicine
Targeting Biological Aging: A New Paradigm for 21st Century MedicineInsideScientific
 
Vitamin D and geriatric syndromes
Vitamin D and geriatric syndromesVitamin D and geriatric syndromes
Vitamin D and geriatric syndromesSamia Ahmed
 

What's hot (20)

Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021
Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021
Bill Faloon's presentation for Age Reversal webinar on Jan 23rd 2021
 
Clinical Trials Update by Bill Faloon at RAADfest 2021
Clinical Trials Update by Bill Faloon at RAADfest 2021Clinical Trials Update by Bill Faloon at RAADfest 2021
Clinical Trials Update by Bill Faloon at RAADfest 2021
 
Age Reversal Update from Bill Faloon on December 15th 2020
Age Reversal Update from Bill Faloon on December 15th 2020Age Reversal Update from Bill Faloon on December 15th 2020
Age Reversal Update from Bill Faloon on December 15th 2020
 
Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021
 
Bill Faloon gives update about human age-reversal clinical studies
Bill Faloon gives update about human age-reversal clinical studiesBill Faloon gives update about human age-reversal clinical studies
Bill Faloon gives update about human age-reversal clinical studies
 
Bill Faloon at DaVinci 50 about stroke risk and blood pressure
Bill Faloon at DaVinci 50 about stroke risk and blood pressureBill Faloon at DaVinci 50 about stroke risk and blood pressure
Bill Faloon at DaVinci 50 about stroke risk and blood pressure
 
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021
Bill Faloon Age Reversal Update at DaVinci 50 Masters Conference 2021
 
Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021Bill Faloon's Keynote Speech from RAADfest 2021
Bill Faloon's Keynote Speech from RAADfest 2021
 
Drug to slow down aging
Drug to slow down agingDrug to slow down aging
Drug to slow down aging
 
The war within our cells
The war within our cellsThe war within our cells
The war within our cells
 
William Faloon on Age Reversal
William Faloon on Age ReversalWilliam Faloon on Age Reversal
William Faloon on Age Reversal
 
Does animal testing help human medicine
Does animal testing help human medicineDoes animal testing help human medicine
Does animal testing help human medicine
 
Supplements Cady At Oliver Seminar
Supplements    Cady At  Oliver SeminarSupplements    Cady At  Oliver Seminar
Supplements Cady At Oliver Seminar
 
유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용
유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용
유전체의학과 미래의학 2 스마트 의학_빅데이터_공개용
 
Engl 115 Essay #3
Engl 115 Essay #3Engl 115 Essay #3
Engl 115 Essay #3
 
Moving from Big Data to Better Models of Disease and Drug Response - Joel Dudley
Moving from Big Data to Better Models of Disease and Drug Response - Joel DudleyMoving from Big Data to Better Models of Disease and Drug Response - Joel Dudley
Moving from Big Data to Better Models of Disease and Drug Response - Joel Dudley
 
Ijsrp p10758
Ijsrp p10758Ijsrp p10758
Ijsrp p10758
 
Autologous Bone Marrow Cell Therapy for Autism: An Open Label Uncontrolled C...
Autologous Bone Marrow Cell Therapy for Autism: An  Open Label Uncontrolled C...Autologous Bone Marrow Cell Therapy for Autism: An  Open Label Uncontrolled C...
Autologous Bone Marrow Cell Therapy for Autism: An Open Label Uncontrolled C...
 
Targeting Biological Aging: A New Paradigm for 21st Century Medicine
Targeting Biological Aging: A New Paradigm for 21st Century MedicineTargeting Biological Aging: A New Paradigm for 21st Century Medicine
Targeting Biological Aging: A New Paradigm for 21st Century Medicine
 
Vitamin D and geriatric syndromes
Vitamin D and geriatric syndromesVitamin D and geriatric syndromes
Vitamin D and geriatric syndromes
 

Similar to 2019.12.08 Bill Faloon Healthy Masters Portugal

Bill Faloon on Interventions Designed to Reverse Human Aging
Bill Faloon on Interventions Designed to Reverse Human AgingBill Faloon on Interventions Designed to Reverse Human Aging
Bill Faloon on Interventions Designed to Reverse Human Agingmaximuspeto
 
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - Copy
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - CopyEffectiveness of Vitamins in the treatment of Prostate Cancer v5 - Copy
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - CopyDr.Mohammad Alamgir
 
Session_7-Jamie_Justice.pptx
Session_7-Jamie_Justice.pptxSession_7-Jamie_Justice.pptx
Session_7-Jamie_Justice.pptxssuser3fe82a
 
Recover from cancer diagnosis
Recover from cancer diagnosisRecover from cancer diagnosis
Recover from cancer diagnosisJohn Bergman
 
cancer prevention.pptx
cancer prevention.pptxcancer prevention.pptx
cancer prevention.pptxChijiokeNsofor
 
Causes And External Factors Of Extrinsic Ageing
Causes And External Factors Of Extrinsic AgeingCauses And External Factors Of Extrinsic Ageing
Causes And External Factors Of Extrinsic AgeingJennifer Lopez
 
Antiaging with Stem Cell & Holistic Approach
Antiaging with Stem Cell & Holistic ApproachAntiaging with Stem Cell & Holistic Approach
Antiaging with Stem Cell & Holistic ApproachDr Pradeep Mahajan
 
GenEpic Product Information
GenEpic Product InformationGenEpic Product Information
GenEpic Product InformationGenEpic
 
A Study On Breast Cancer
A Study On Breast CancerA Study On Breast Cancer
A Study On Breast CancerAdriana Wilson
 
Effectiveness Of Successful Resilience Programs For Nurses
Effectiveness Of Successful Resilience Programs For NursesEffectiveness Of Successful Resilience Programs For Nurses
Effectiveness Of Successful Resilience Programs For NursesAnna Shaw
 
Phytosterols for Cancer Treatment
Phytosterols for Cancer TreatmentPhytosterols for Cancer Treatment
Phytosterols for Cancer TreatmentJosh Nooner
 
Phytosterols for cancer treatment
Phytosterols for cancer treatmentPhytosterols for cancer treatment
Phytosterols for cancer treatmentJosh Nooner
 
4th july 2020 daily global regional and local rice e newsletter
4th july 2020  daily global regional and local rice e newsletter4th july 2020  daily global regional and local rice e newsletter
4th july 2020 daily global regional and local rice e newsletterRiceplus Magazine
 
4th july 2020 daily global regional and local rice e newsletter
4th july 2020  daily global regional and local rice e newsletter4th july 2020  daily global regional and local rice e newsletter
4th july 2020 daily global regional and local rice e newsletterRiceplus Magazine
 

Similar to 2019.12.08 Bill Faloon Healthy Masters Portugal (20)

Bill Faloon on Interventions Designed to Reverse Human Aging
Bill Faloon on Interventions Designed to Reverse Human AgingBill Faloon on Interventions Designed to Reverse Human Aging
Bill Faloon on Interventions Designed to Reverse Human Aging
 
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - Copy
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - CopyEffectiveness of Vitamins in the treatment of Prostate Cancer v5 - Copy
Effectiveness of Vitamins in the treatment of Prostate Cancer v5 - Copy
 
Session_7-Jamie_Justice.pptx
Session_7-Jamie_Justice.pptxSession_7-Jamie_Justice.pptx
Session_7-Jamie_Justice.pptx
 
Recover from cancer diagnosis
Recover from cancer diagnosisRecover from cancer diagnosis
Recover from cancer diagnosis
 
md longevity
md longevitymd longevity
md longevity
 
Extended life span
Extended life spanExtended life span
Extended life span
 
cancer prevention.pptx
cancer prevention.pptxcancer prevention.pptx
cancer prevention.pptx
 
Cancer prevention
Cancer preventionCancer prevention
Cancer prevention
 
Causes And External Factors Of Extrinsic Ageing
Causes And External Factors Of Extrinsic AgeingCauses And External Factors Of Extrinsic Ageing
Causes And External Factors Of Extrinsic Ageing
 
Antiaging with Stem Cell & Holistic Approach
Antiaging with Stem Cell & Holistic ApproachAntiaging with Stem Cell & Holistic Approach
Antiaging with Stem Cell & Holistic Approach
 
GenEpic Product Information
GenEpic Product InformationGenEpic Product Information
GenEpic Product Information
 
A Study On Breast Cancer
A Study On Breast CancerA Study On Breast Cancer
A Study On Breast Cancer
 
Effectiveness Of Successful Resilience Programs For Nurses
Effectiveness Of Successful Resilience Programs For NursesEffectiveness Of Successful Resilience Programs For Nurses
Effectiveness Of Successful Resilience Programs For Nurses
 
Daily Health Update for 06/24/2015 for Rode Chiropractic of Poway CA 92064
Daily Health Update for  06/24/2015 for Rode Chiropractic of Poway CA 92064Daily Health Update for  06/24/2015 for Rode Chiropractic of Poway CA 92064
Daily Health Update for 06/24/2015 for Rode Chiropractic of Poway CA 92064
 
Phytosterols for Cancer Treatment
Phytosterols for Cancer TreatmentPhytosterols for Cancer Treatment
Phytosterols for Cancer Treatment
 
Phytosterols for cancer treatment
Phytosterols for cancer treatmentPhytosterols for cancer treatment
Phytosterols for cancer treatment
 
Chemoprevention Essay
Chemoprevention EssayChemoprevention Essay
Chemoprevention Essay
 
Daily Health Update for 06/04/15 from Poway Chiropractor Dr. Rode of Rode Chi...
Daily Health Update for 06/04/15 from Poway Chiropractor Dr. Rode of Rode Chi...Daily Health Update for 06/04/15 from Poway Chiropractor Dr. Rode of Rode Chi...
Daily Health Update for 06/04/15 from Poway Chiropractor Dr. Rode of Rode Chi...
 
4th july 2020 daily global regional and local rice e newsletter
4th july 2020  daily global regional and local rice e newsletter4th july 2020  daily global regional and local rice e newsletter
4th july 2020 daily global regional and local rice e newsletter
 
4th july 2020 daily global regional and local rice e newsletter
4th july 2020  daily global regional and local rice e newsletter4th july 2020  daily global regional and local rice e newsletter
4th july 2020 daily global regional and local rice e newsletter
 

More from maximuspeto

Bill Faloon's 2023 RAADfest Presentation Slides
Bill Faloon's 2023 RAADfest Presentation SlidesBill Faloon's 2023 RAADfest Presentation Slides
Bill Faloon's 2023 RAADfest Presentation Slidesmaximuspeto
 
Bill Faloon on What is Delaying Regenerative Medicine in 2023
Bill Faloon on What is Delaying Regenerative Medicine in 2023Bill Faloon on What is Delaying Regenerative Medicine in 2023
Bill Faloon on What is Delaying Regenerative Medicine in 2023maximuspeto
 
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentation
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project PresentationBill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentation
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentationmaximuspeto
 
Bill Faloon on what's delaying regenerative medicine in 2023.pptx
Bill Faloon on what's delaying regenerative medicine in 2023.pptxBill Faloon on what's delaying regenerative medicine in 2023.pptx
Bill Faloon on what's delaying regenerative medicine in 2023.pptxmaximuspeto
 
Fruit Fly Combo Treatment Life Extension.pptx
Fruit Fly Combo Treatment Life Extension.pptxFruit Fly Combo Treatment Life Extension.pptx
Fruit Fly Combo Treatment Life Extension.pptxmaximuspeto
 
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversal
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age ReversalBill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversal
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversalmaximuspeto
 
FDA petition slides.pptx
FDA petition slides.pptxFDA petition slides.pptx
FDA petition slides.pptxmaximuspeto
 
Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021
Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021
Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021maximuspeto
 

More from maximuspeto (8)

Bill Faloon's 2023 RAADfest Presentation Slides
Bill Faloon's 2023 RAADfest Presentation SlidesBill Faloon's 2023 RAADfest Presentation Slides
Bill Faloon's 2023 RAADfest Presentation Slides
 
Bill Faloon on What is Delaying Regenerative Medicine in 2023
Bill Faloon on What is Delaying Regenerative Medicine in 2023Bill Faloon on What is Delaying Regenerative Medicine in 2023
Bill Faloon on What is Delaying Regenerative Medicine in 2023
 
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentation
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project PresentationBill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentation
Bill Faloon at HEALinc Summit April 20th 2023 Perpetual Project Presentation
 
Bill Faloon on what's delaying regenerative medicine in 2023.pptx
Bill Faloon on what's delaying regenerative medicine in 2023.pptxBill Faloon on what's delaying regenerative medicine in 2023.pptx
Bill Faloon on what's delaying regenerative medicine in 2023.pptx
 
Fruit Fly Combo Treatment Life Extension.pptx
Fruit Fly Combo Treatment Life Extension.pptxFruit Fly Combo Treatment Life Extension.pptx
Fruit Fly Combo Treatment Life Extension.pptx
 
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversal
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age ReversalBill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversal
Bill Faloon's RAADfest 2022 Keynote Presentation slides about Age Reversal
 
FDA petition slides.pptx
FDA petition slides.pptxFDA petition slides.pptx
FDA petition slides.pptx
 
Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021
Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021
Bill Faloon on Extracellular Vesicles from amniotic fluid RAADfest 2021
 

Recently uploaded

CPR.nursingoutlook.pdf , Bsc nursing student
CPR.nursingoutlook.pdf , Bsc nursing studentCPR.nursingoutlook.pdf , Bsc nursing student
CPR.nursingoutlook.pdf , Bsc nursing studentsaileshpanda05
 
blood bank management system project report
blood bank management system project reportblood bank management system project report
blood bank management system project reportNARMADAPETROLEUMGAS
 
The Importance of Mental Health: Why is Mental Health Important?
The Importance of Mental Health: Why is Mental Health Important?The Importance of Mental Health: Why is Mental Health Important?
The Importance of Mental Health: Why is Mental Health Important?Ryan Addison
 
Basic structure of hair and hair growth cycle.pptx
Basic structure of hair and hair growth cycle.pptxBasic structure of hair and hair growth cycle.pptx
Basic structure of hair and hair growth cycle.pptxkomalt2001
 
ayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologypptayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologypptPradnya Wadekar
 
power point presentation of Clinical evaluation of strabismus
power point presentation of Clinical evaluation  of strabismuspower point presentation of Clinical evaluation  of strabismus
power point presentation of Clinical evaluation of strabismusChandrasekar Reddy
 
Adenomyosis or Fibroid- making right diagnosis
Adenomyosis or Fibroid- making right diagnosisAdenomyosis or Fibroid- making right diagnosis
Adenomyosis or Fibroid- making right diagnosisSujoy Dasgupta
 
Mental health Team. Dr Senthil Thirusangu
Mental health Team. Dr Senthil ThirusanguMental health Team. Dr Senthil Thirusangu
Mental health Team. Dr Senthil Thirusangu Medical University
 
Good Laboratory Practice (GLP) in Pharma-LikeWays.pptx
Good Laboratory Practice (GLP) in Pharma-LikeWays.pptxGood Laboratory Practice (GLP) in Pharma-LikeWays.pptx
Good Laboratory Practice (GLP) in Pharma-LikeWays.pptxLikeways
 
Female Reproductive Physiology Before Pregnancy
Female Reproductive Physiology Before PregnancyFemale Reproductive Physiology Before Pregnancy
Female Reproductive Physiology Before PregnancyMedicoseAcademics
 
Role of Soap based and synthetic or syndets bar
Role of  Soap based and synthetic or syndets barRole of  Soap based and synthetic or syndets bar
Role of Soap based and synthetic or syndets barmohitRahangdale
 
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptxANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptxWINCY THIRUMURUGAN
 
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.aarjukhadka22
 
EXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung functionEXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung functionkrishnareddy157915
 
Clinical Research Informatics Year-in-Review 2024
Clinical Research Informatics Year-in-Review 2024Clinical Research Informatics Year-in-Review 2024
Clinical Research Informatics Year-in-Review 2024Peter Embi
 
Physiology of Smooth Muscles -Mechanics of contraction and relaxation
Physiology of Smooth Muscles -Mechanics of contraction and relaxationPhysiology of Smooth Muscles -Mechanics of contraction and relaxation
Physiology of Smooth Muscles -Mechanics of contraction and relaxationMedicoseAcademics
 
Pregnacny, Parturition, and Lactation.pdf
Pregnacny, Parturition, and Lactation.pdfPregnacny, Parturition, and Lactation.pdf
Pregnacny, Parturition, and Lactation.pdfMedicoseAcademics
 
historyofpsychiatryinindia. Senthil Thirusangu
historyofpsychiatryinindia. Senthil Thirusanguhistoryofpsychiatryinindia. Senthil Thirusangu
historyofpsychiatryinindia. Senthil Thirusangu Medical University
 
World-TB-Day-2023_Presentation_English.pptx
World-TB-Day-2023_Presentation_English.pptxWorld-TB-Day-2023_Presentation_English.pptx
World-TB-Day-2023_Presentation_English.pptxsumanchaulagain3
 
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...Shubhanshu Gaurav
 

Recently uploaded (20)

CPR.nursingoutlook.pdf , Bsc nursing student
CPR.nursingoutlook.pdf , Bsc nursing studentCPR.nursingoutlook.pdf , Bsc nursing student
CPR.nursingoutlook.pdf , Bsc nursing student
 
blood bank management system project report
blood bank management system project reportblood bank management system project report
blood bank management system project report
 
The Importance of Mental Health: Why is Mental Health Important?
The Importance of Mental Health: Why is Mental Health Important?The Importance of Mental Health: Why is Mental Health Important?
The Importance of Mental Health: Why is Mental Health Important?
 
Basic structure of hair and hair growth cycle.pptx
Basic structure of hair and hair growth cycle.pptxBasic structure of hair and hair growth cycle.pptx
Basic structure of hair and hair growth cycle.pptx
 
ayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologypptayurvedic formulations herbal drug technologyppt
ayurvedic formulations herbal drug technologyppt
 
power point presentation of Clinical evaluation of strabismus
power point presentation of Clinical evaluation  of strabismuspower point presentation of Clinical evaluation  of strabismus
power point presentation of Clinical evaluation of strabismus
 
Adenomyosis or Fibroid- making right diagnosis
Adenomyosis or Fibroid- making right diagnosisAdenomyosis or Fibroid- making right diagnosis
Adenomyosis or Fibroid- making right diagnosis
 
Mental health Team. Dr Senthil Thirusangu
Mental health Team. Dr Senthil ThirusanguMental health Team. Dr Senthil Thirusangu
Mental health Team. Dr Senthil Thirusangu
 
Good Laboratory Practice (GLP) in Pharma-LikeWays.pptx
Good Laboratory Practice (GLP) in Pharma-LikeWays.pptxGood Laboratory Practice (GLP) in Pharma-LikeWays.pptx
Good Laboratory Practice (GLP) in Pharma-LikeWays.pptx
 
Female Reproductive Physiology Before Pregnancy
Female Reproductive Physiology Before PregnancyFemale Reproductive Physiology Before Pregnancy
Female Reproductive Physiology Before Pregnancy
 
Role of Soap based and synthetic or syndets bar
Role of  Soap based and synthetic or syndets barRole of  Soap based and synthetic or syndets bar
Role of Soap based and synthetic or syndets bar
 
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptxANATOMICAL FAETURES OF BONES  FOR NURSING STUDENTS .pptx
ANATOMICAL FAETURES OF BONES FOR NURSING STUDENTS .pptx
 
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
Bulimia nervosa ( Eating Disorders) Mental Health Nursing.
 
EXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung functionEXERCISE PERFORMANCE.pptx, Lung function
EXERCISE PERFORMANCE.pptx, Lung function
 
Clinical Research Informatics Year-in-Review 2024
Clinical Research Informatics Year-in-Review 2024Clinical Research Informatics Year-in-Review 2024
Clinical Research Informatics Year-in-Review 2024
 
Physiology of Smooth Muscles -Mechanics of contraction and relaxation
Physiology of Smooth Muscles -Mechanics of contraction and relaxationPhysiology of Smooth Muscles -Mechanics of contraction and relaxation
Physiology of Smooth Muscles -Mechanics of contraction and relaxation
 
Pregnacny, Parturition, and Lactation.pdf
Pregnacny, Parturition, and Lactation.pdfPregnacny, Parturition, and Lactation.pdf
Pregnacny, Parturition, and Lactation.pdf
 
historyofpsychiatryinindia. Senthil Thirusangu
historyofpsychiatryinindia. Senthil Thirusanguhistoryofpsychiatryinindia. Senthil Thirusangu
historyofpsychiatryinindia. Senthil Thirusangu
 
World-TB-Day-2023_Presentation_English.pptx
World-TB-Day-2023_Presentation_English.pptxWorld-TB-Day-2023_Presentation_English.pptx
World-TB-Day-2023_Presentation_English.pptx
 
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
FDMA FLAP - The first dorsal metacarpal artery (FDMA) flap is used mainly for...
 

2019.12.08 Bill Faloon Healthy Masters Portugal

  • 1. Age Reversal Update Healthy Masters 2019 Portugal William Faloon
  • 2. age-reversal.net This entire presentation and info about our research available at:
  • 3. “A triple drug combination has been used to extend the lifespan of fruit flies by 48% in a new study.” https://www.nextbigfuture.com/2019/10/rapamycin-and-two-other-drugs-extends-lifespan-twice-as-much-as-any-other-drug-combo.html Rapamycin and Two Other Drugs Extends Lifespan Twice As Much As Any Other Drug Combo
  • 4. “Previousstudiesinfruitflieshave achievedlifespan extensions ofabout 5-20% …sowefounditwasquiteremarkable thatthisdrugcombinationenabled themtolive Castillo-Quan, Jorge Iván, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Grönke, Yvonne Hinze, T. Keith Blackwell, Ivana Bjedov, and Linda Partridge. "A triple drug combination targeting components of the nutrient-sensing network maximizes longevity." Proceedings of the National Academy of Sciences 116, no. 42 (2019): 20817-20819. September 30, 2019 Combined Interventions More Effective than SingleAgent Therapy
  • 5. PNAS October 15, 2019 116 (42) 20817-20819; first published September 30, 2019 https://doi.org/10.1073/pnas.1913212116 Rapamycin Lithium Dasatinib-like Drug+ + Fruit Fly Lifespan Extension by 48% = “…a combination of drugs already approved for human use is a viable strategy to maximize animal longevity…” This recent study supports the stairstep approach advocated to enable us to live significantly longer September 30, 2019
  • 6. Fruit flies received drugs separately and/or in combination.  Each drug individually extended lifespan by 11%  Pairing two drugs extended lifespan roughly 30%  Three drugs combined extended lifespan by 48% Castillo-Quan, Jorge Iván, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Grönke, Yvonne Hinze, T. Keith Blackwell, Ivana Bjedov, and Linda Partridge. "A triple drug combination targeting components of the nutrient-sensing network maximizes longevity." Proceedings of the National Academy of Sciences 116, no. 42 (2019): 20817-20819. Combination Treatments are Essential September 30, 2019
  • 7. Interventions that may improve your odds of living to year 2030
  • 8. …they are optimistic that a person’s biological age can be reversed.” Age markers reversed by 2.5 years! “ScientistsatInterveneImmuneandStanford MedicalCenterhaveproventhat‘epigenetic agingcanbereversedinhumans’... Cocktail Of Drugs Gives First Hope That ‘Biological Age’ Can Be Reversed https://forbes.com/sites/robinseatonjefferson/2019/09/09/cocktail-of-drugs-gives-first-hope-that-biological-age-can-be-reversed/
  • 9. “Reversal of epigenetic aging and immunosenescent trends in humans.” Aging Cell; Sept 2019 Combination Therapy also Effective in Humans 1) Human growth hormone 2) DHEA 3) Metformin Study conducted by Dr. Greg Fahy in collaboration with researchers from Stanford University and UCLA consisted of individualized doses of: Study subjects also provided with daily vitamin D3 and zinc.
  • 10. https://www.dailymail.co.uk/health/article-7435427/Aging- REVERSED-small-group-men-study-reveals.htmll Oct.22,2019Turning Back Time! “Aging is REVERSED in men using a cocktail of growth hormones and diabetes drugs in study that saw test group shed 2.5 biological years.”
  • 11. Type II diabetics taking metformin: United Kingdom Diabetes Study ►32% reduced risk of diabetic complications ►42% reduced risk for diabetes-related death ►36% reduced all-cause mortality risk Study Results Found in January 1995 British Medical Journal; Jan 14, 1995;” United Kingdom Prospective Diabetes Study (UKPDS)
  • 12. Study Results Found on March 21st 2017 Journal of the American Medical Association JAMA. Published online March 21, 2017. doi:10.1001/jama.2016.17844 Metformin studied in prediabetic patients. Compared to placebo 850 mg of metformin two times a day: Reduced type II diabetes risk 31% In patients under age 60: metformin reduced diabetic risk by 58%. “Metformin can cause weight loss…”Quote:
  • 13. Sept. 2017 Metformin Demonstrates Therapeutic Effects Against Colon Cancer Am J Med Sci. 2017 Sep;354(3):246-251. doi: 10.1016/j.amjms.2017.05.006. Epub 2017 May 19. Metformin Has Positive Therapeutic Effects in Colon Cancer and Lung Cancer. Colon Cancer Metformin Patients Non-Metformin Patients Recurrences 4% 19% Metastases 23% 46% 5-Year Survival 57% 37% Deaths 48% 76% (Metformin boosts AMPK activity and indirectly inhibits mTOR) Conclusion: “Metformin therapy is associated with significantly better prognosis in patients with colon cancer” Caveat: Some diabetics in control group treated with insulin or sulfonylurea drugs that promote tumor cell propagation. Diabetics on metformin showed these benefits compared to diabetics not prescribed metformin:
  • 14. Diabetics taking metformin have lower cancer rates Metformin Prevents Cancer MD Anderson Cancer Center found risk of pancreatic cancer was 62% lower in diabetics using metformin. Li D, Yeung SC, Hassan MM, Konopleva M, Abbruzzese JL. Antidiabetic therapies affect risk of pancreatic cancer. Gastroenterology. 2009 Aug;137(2):482-8.
  • 16. Metformin Anti-aging Trial Gets Green-light https://www.longevity.technology/worlds-first-anti-aging-trial-gets-green-light/ Sept 4, 2019 1958 - Metformin approved as anti-diabetic drug in England 1995 - Life Extension® lists metformin as anti-aging drug 2015 - FDA approves first anti-aging study of a drug (metformin) 2019 - Metformin study receives $75 million funding ($40 million from anonymous donor)
  • 17. Life Extension recommended metformin 24 years ago… the FDA went berserk! March 1995
  • 18. Catastrophic Loss of Life A 2019 study tabulated reductions in cardiovascular mortality in type II diabetics using metformin.1 Life Extension® then calculated how many cardiovascular deaths may have occurred in response to metformin’s 37-year delay. Almost 4 million American diabetics may have died because of the delay in this one drug (metformin) becoming available. This exceeds the death toll of all wars America has ever fought. 1. Association of Treatment With Metformin vs Sulfonylurea With Major Adverse Cardiovascular Events Among Patients With Diabetes and Reduced Kidney Function. JAMA. 2019 September 19:1-11.
  • 19. We Don’t Have Time for Delayed Age Reversal
  • 21. Statistically Significant + Meaningful Age Reversal in 12 Months Outcome Objectives: $550,000 + donated/discounted services Human Age Reversal Project Vitality in Aging Interventions Trial Study Cost: Major Funding Provided by:
  • 22. Fund research with tax deductible donations: Human Age Reversal Project Make checks payable to: Human Age Reversal Project 300 NE 20th St. #409 Boca Raton, FL 33431 Or donate online: age-reversal.net/donate
  • 23. Age Reversal Interventions 1)Target 5 calorie restriction pathways 2) Reduce/resolve inflammation 3) Telomere lengthening 4) Selective remove senescent cells 5) Restore youthful methylation age-reversal.net
  • 24. VIA Interventions Trial Price per Study Subject: ZERO Estimated Value per Study Subject: >$10,000
  • 25. Age Reversal Interventions Autophagy Resolve inflammation Remove senescent cells Restore youthful methylation Lengthen telomeres AMPK/ mTOR Sirtuins - NAD+ Exosomes
  • 26. Trial Parameters > Open label (no placebo group) > 50 healthy people aged 50-75 years Initial Phase Recruitment/Baseline Testing: October 3rd 2019 – December 15th 2019 Vitality in Aging Intervention Trial
  • 27. Vitality in Aging Interventions Trial Timeline
  • 28. Vitality in Aging Interventions Trial Intervention #1 Calorie Restriction Mimetics
  • 29. 12% Calorie Reduction Improves Biological Age Scores by 1.5 Years 2018 Published Human study measures 8 Aging Biomarkers Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis, J Gerontol A Biol Sci Med Sci. 2018 Jan; 73(1): 4-10.
  • 30. Intervention:1 Targeting Calorie Restriction Pathways Metformin Metformin Rapamycin, metformin Pterostilbene, nicotinamide Nicotinamide riboside Rapamycin, glucosamine Beta-lapachone ↓Insulin/IGF-1 ↑AMPK ↓mTOR ↑Sirtuins ↑ NAD+ ↑Autophagy ↑NAD/NADH ratio
  • 32. Vitality in Aging Interventions Trial Senolytics Selective removal of senescent cells Intervention #2
  • 33. July 9, 2018 Magazine “It’slooking like veryoldmice are able to substantially improve their health span, reduce or delay age-related diseases and increase their survival.” They calculated that if only one in 7,000 to 15,000 cells is senescent, then age-related problems in physical function started to appear in the mice. Like a contagion, senescent cells seem to pass on their accelerated aging abilities to healthy cells by releasing a number of factors that can cause tissues like muscle to deteriorate. Mice given senescent cells and the senolytic compounds lived 36% longer than animals with senescent cell transplants who were not given the drugs. How Scientists Are Testing Cancer Drugs to Slow Down Aging
  • 34. Drug to clear 'zombie cells' from body could be first anti-aging treatment after ‘impressive’ human trial https://www.telegraph.co.uk/science/2019/01/08/drug-clear-zombie-cells-body-could-first-anti-ageing-treatment/ Jan. 8, 2019 “A drug to fight aging may finally be on the horizon after the first trial in humans showed ‘impressive’ results.” “The treatment clears out dead cells even when the immune system no longer can.”
  • 35. This drug cocktail reduced signs of age-related diseases and extended life in mice and human cells Senolytic Delay May = Death “Group led by Mayo Clinic anti-aging researcher James Kirkland not only offers a clear look at the power of senescent cells to drive the aging process, but also a pharmaceutical cocktail that, in mice at least, can slow and even reverse it. Compared to mice who aged normally, those who started getting the dasatinib-quercetin cocktail at an age equivalent to 75 to 90 years in humans ended up living roughly 36% longer, and with better physical function. In human cells in a test tube and in mice bearing human senescent cells, the dasatinib-quercetin cocktail showed equally promising results, targeting senescent cells while leaving other cells intact. Aging…is beginning to look more and more like a disease — and a treatable one at that. ScientistsAre Testing CancerDrugstoSlowDownAging July 10, 2019
  • 36. SEPTEMBER 17, 2018 Scientific Discovery and the Future of Medicine Journal of the American Medical Association “…many human pathologic conditions are associated with the presence of senescent cells.” “Interventions aimed at eliminating those senescent cells, commonly called senolytic, have also been shown to improve health and extend life in various mouse disease models. “If senolytics are shown to be safe and effective in humans, they could transform care of older adults and patients with multiple chronic diseases.” Reference: “Aging, Cell Senescence, and Chronic Disease:Emerging Therapeutic Strategies.”; Journal of the American Medical Association (JAMA) September 17th 2018.
  • 37. “Moreover, tremendous advances are being made in our understanding of the science of aging, yielding exciting potential treatments that may alter the course of this inevitable process.5 One aspect of this work relates to “senolytics,” the study of ways to either eliminate senescent cells that may have deleterious effects or slow or reverse the aging process by restoring cells’ lost function. “Enabling Healthful Aging for All — The National Academy of Medicine Grand Challenge in Healthy Longevity” https://www.nejm.org/doi/full/10.1056/NEJMp1912298?query=TOC October 31, 2019 Purging failed brain insulation cells lessened damage, improved cognition in Alzheimer's mouse model
  • 38. Selective removal of senescent cells - Age-related accumulation of senescent cells contributes to atherosclerosis, aging of the eye (cataracts, AMD), osteoporosis, skin and brain aging, Kirkland and colleagues at Mayo Clinic show that senescent cells are selectively eliminated by “senolytic” drugs. Senolytic Cocktail of: Senolytics 1) Dasatinib 2) Quercetin 3) Fisetin
  • 40. 1) Fish oil: Boost omega-3 index > 10% Reduce and Resolve Chronic Inflammation 2) Resolvins: Return tissues to health Inflammaging major cause of aging and contributes to the global loss of Sirt1 function. We intend to use omega-3 fatty acids and other fatty acids to increase resolvins, protectins, and maresins with a target of a minimum of 10% omega-3 index.
  • 42. Telomereshortening normally occurs atarateof0.9%/year. Telomere Lengthening 1) Exercise 2) Stress Control 3) Healthy Diet 4) Omega-3 fatty acids Onesmallprospectivecontrolledstudyinolder menshowedthattelomerescouldbelengthened by2%peryearwithacombinationof:
  • 44. “TheroleofDNA methylationin epigeneticsofaging”  Epigenetics, especially DNA methylation, plays a mechanistic role in aging.  Epigenetic clocks are best biomarkers for predicting human mortality.  DNAmethylationinfluencedbymetformin,caloric restriction and rapamycin treatment in mice.  This may reverse/prevent 20% to 40% of the age-related changes in DNA methylation. Pharmacol Ther. 2019 March; 195:172-185. doi:10.1016/j.pharmthera.2018.11.001
  • 45. Methods of Balancing Methylation Pharmacol Ther. 2019 March; 195:172-185. doi:10.1016/j.pharmthera.2018.11.001 Metformin CalorieRestrictionMimetics Rapamycin
  • 46. LS/tandemmassspectrometrybasedtesting Quantitativeb-galactosidasestaining,p16INK4a,etc) Neurovision – Mayo Clinic CD38 Johns Hopkins Aging Biomarker Tests Vitality in Aging Interventions Trial More Accurate FlowFISH- Based Telomere Length Tests Newer DNA Methylation Age Tests NAD+, NAD/NADH ratio, and NAD+ metabolite tests Cell Senescence Tests Univ of British Columbia/UCLA Galactosidasestaining,p16INK4a,skinpunch NanoSomiX Exosome tests for predicting Alzheimer’s disease 10 years prior to onset of memory loss Age Management Panel Comprehensive blood biomarkers with Levine Biological Age Calculator
  • 47. Healthy Subjects in order to Measure Meaningful Age Reversal in 12 Months Strict Inclusion Criteria for Study Subjects Vitality in Aging Interventions Trial Exercise (10,000 step equivalent each day) Healthy diet patterns (no junk foods) Restful sleep patterns (no benzodiazepines) Body Mass Index: 18-24 (no significant central fat mass) No serious preexisting disorders No prescription narcotics or recreational drugs Target LDL below 80 mg/dl Omega-3 Index > 8% (achievablewithhighdosefishoil)
  • 48. Long Term Funding Sources Will Be Needed Human Age Reversal Project Bill Faloon Donations of Physicians’ Time Funding Need: > $550,000 Donations Received to Date: >$625,000 20 Vitality In Aging Interventions Trial SOURCES OF FUNDING:
  • 49. New charity to fund research with tax deductible donations: Human Age Reversal Project Make checks payable to: Human Age Reversal Project 300 NE 20th St. #409 Boca Raton, FL 33431 Or donate online: age-reversal.net/donate
  • 50. Omega-3 IndexLiver-Kidney Function Cardiovascular Inflammatory Hormones Lipids (full-spectrum) NAD+ Glycemic Markers Blood Cell Counts Vitamin D Insulin Resistance Growth Factors
  • 51. NicotinamideFull ADPR NAAD ADPR NAMN NAD + metabolites PADPH NAM MeNAM NADP+
  • 53. Interventions that may improve your odds of living to year 2030
  • 54. Lifespans not limited by senescence Neocortex Connects- Converts to the Cloud Years 2030 2050 Stair Step Approach to Infinite Longevity Singularity + A.I. enables limitless self-improvement.
  • 55. Hotel magnate Barron Hilton died of natural causes at the age of 91. He left about 97% of his estate to Conrad N. Hilton Foundation, which expects to grow its endowment from $2.9 billion to $6.3 billion www.foxbusiness.com/business-leaders/barron-hilton-fortune-estate-foundation Who missed the longevity boat? Barron Hilton (1927-2019) Expiration date: Sept. 19, 2019 Net worth > $2.9 billion Paris Hilton Barron Hilton
  • 56. Too Wealthy to Die at Age 65 Paul Allen, Chairman of the Seattle Seahawks co-founded Microsoft in 1975. Diagnosed and treated for non-Hodgkin lymphoma in 2009. Cancer returned in 2018. He died from septic shock. Paul Allen was philanthropist and donated to medical research… but did NOT make it his priority! https://www.nytimes.com/2018/10/15/obituaries/paul-allen-dead.html Paul Allen (1953-2018) Net worth > $26.1 billion Expiration date: Oct. 15, 2018
  • 57. Too Wealthy to Die at Age 58 Blake Nordstrom, company co-president, dies unexpectedly at 58 from lymphoma. At the time, he described his condition as "treatable" and said he planned to "continue to work throughout this process as normal." https://www.cnn.com/2019/01/02/business/blake-nordstrom-obit/ Blake Nordstrom(1961-2019) Net worth > $1.5 billion Expiration date: Jan. 2, 2019
  • 58. Who Missed the Longevity Boat Robert "Bob" McNair, billionaire founder and owner of the Houston Texans died at age 81. He battled squamous cell skin cancer and then leukemia for about 20 years. https://www.forbes.com/profile/robert-mcnair/#130c78d9251a RobertMcNair (1937-2018) Net worth ~ $3.8 billion Expiration date: Nov. 23, 2018 Wealthy And Famous That Expired In 2018
  • 59. Who Missed the Longevity Boat Herb Kelleher, the eccentric founder of Southwest Airlines who helped revolutionize low-cost air travel in 1971. Died at age 87. https://www.cnn.com/2019/01/03/business/southwest-airlines-founder-herb-kelleher-obit Herb Kelleher(1931-2019) Net worth ~ $2.5 billion Expiration date: Jan. 3, 2019 Wealthy And Famous That Expired In 2019
  • 60. “Just a year ago I felt immortal, wearing my age with pride, even joking about it.” https://www.nytimes.com/2019/09/11/business/boone-pickens-dead.html Who missed the longevity boat? T. Boone Pickens (1928-2018) Expiration date: Sept. 11, 2019 Net worth > $950 million In 2016 T. Boone Pickens wrote: One year later suffered series of strokes and a fall. Dead at age 91.
  • 61. T. Boone Pickens Largely Funded $260 Million Oklahoma State University Stadium (He made many other charitable donations to biomedical research)
  • 62. Fund research with tax deductible donations: Human Age Reversal Project Make checks payable to: Human Age Reversal Project 300 NE 20th St. #409 Boca Raton, FL 33431 Or donate online: age-reversal.net/donate
  • 63. November,2009 No Human Age-Reversal Intervention Identified We Were Doomed 10 Years Ago
  • 64. Huge Advances in Only 10 Years No Way to Reverse Aging Manhattan Beach Summit Attendees November 2009 Many Potential Methods 2009 2019
  • 65. 2009-2019 Senolytics NAD+ Sirtuins mTOR-inhibition AMPK Activation Umbilical Cord Plasma/Blood Exosomes from Young Cells Mesenchymal Stem Cells Immune Restoration Mitochondria Restoration Multiple Regenerative Interventions
  • 69. Fund research with tax deductible donations: Human Age Reversal Project Make checks payable to: Human Age Reversal Project 300 NE 20th St. #409 Boca Raton, FL 33431 Or donate online: age-reversal.net/donate
  • 70. http://med.miami.edu/news/interdisciplinary-stem-cell-institute-at-the-university-of-miami-receives-2 Interdisciplinary Stem Cell Institute at the University of Miami Receives $25 Million Donation “The Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine has received a $25 million donation from the Soffer Family Foundation.” “The funding will allow the institute to continue its groundbreaking stem cell research… in fields of cardiology, sports medicine, and aging-related conditions.” October 8th 2019
  • 71. Unparalleled Track Record of Biomedical Innovation Established 1977
  • 72. age-reversal.net This entire presentation and info about our research available at:

Editor's Notes

  1. In about 15 minutes, I am going to make an announcement that is unprecedented in the history of medical science. In fact what is being unveiled right here at RAADfest is unparalleled in the history of the human race.
  2. In about 15 minutes, I am going to make an announcement that is unprecedented in the history of medical science. In fact what is being unveiled right here at RAADfest is unparalleled in the history of the human race.
  3. I changed order of paragraphs.
  4. In about 15 minutes, I am going to make an announcement that is unprecedented in the history of medical science. In fact what is being unveiled right here at RAADfest is unparalleled in the history of the human race.
  5. In about 15 minutes, I am going to make an announcement that is unprecedented in the history of medical science. In fact what is being unveiled right here at RAADfest is unparalleled in the history of the human race.
  6. In about 15 minutes, I am going to make an announcement that is unprecedented in the history of medical science. In fact what is being unveiled right here at RAADfest is unparalleled in the history of the human race.