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POINTS ABOUT
DRUGS
medpgnotes
POINTS ABOUT DRUGS
www.medpgnotes.com
1
Contents
ANTICHOLINESTERASE..................................................................................................................................................................................................................................2
AUTACOIDS..........................................................................................................................................................................................................................................................2
BETA BLOCKERS................................................................................................................................................................................................................................................2
BISPHOSPHONATES.........................................................................................................................................................................................................................................2
CATARACT NUGGETS.......................................................................................................................................................................................................................................3
CONDITION AND SPECIFIC DRUG...............................................................................................................................................................................................................4
CONDITION AND SPECIFIC SURGERY.......................................................................................................................................................................................................5
DIABETES NUGGETS ........................................................................................................................................................................................................................................6
DIFFERENT USAGE OF DRUGS.....................................................................................................................................................................................................................7
DRUG OF CHOICE...............................................................................................................................................................................................................................................7
DRUG KINETICS............................................................................................................................................................................................................................................... 11
FEW DRUG INTERACTIONS........................................................................................................................................................................................................................ 11
MECHANISM OF ACTION OF DRUGS....................................................................................................................................................................................................... 12
MONOCLONAL ANTIBODIES...................................................................................................................................................................................................................... 19
NITRATES NUGGET ....................................................................................................................................................................................................................................... 19
OPIOID NUGGET.............................................................................................................................................................................................................................................. 20
PRODRUGS ........................................................................................................................................................................................................................................................ 20
SAFEST DRUGS IN PREGNANCY NUGGET............................................................................................................................................................................................. 21
STEROID DRUGS ............................................................................................................................................................................................................................................. 21
TREATMENT OF CHOICE............................................................................................................................................................................................................................. 22
POINTS ABOUT DRUGS
www.medpgnotes.com
2ANTICHOLINESTERASE
ANTICHOLINESTERASE
Naturally occurring Anticholinesterase
Lipid Soluble Anticholinesterase
Blood brain barrier crossing Anticholinesterase
Physostigmine
Anticholinesterase used in Myasthenia Gravis Neostigmine/Pyridostigmine
Anticholinesterase used for Diagnosis of Mtasthenia
Gravis
Edrophonium
Anticancer showing Anticholinesterase Property Irinotecan
AUTACOIDS
FUNCTION AUTAOIDS
Most Important chemical elevating Hypothalamic
setpoint
PGE2
Vasoconstrictor PGF2
Prostaglandins causing Renal Vasodilataion PGI2,PGE2
Vasodilatation in blood vessels PGI2,PGE2,PGF2α
Platelet Aggregation TXA2
Inhibition of Platelet aggregation PGI2
Chemotactic LTB4
Bronchoconstrictor
Slow reacting substance of anaphylaxis(SRSA)
LTC4
LTD4
LTE4
BETA BLOCKERS
Most Cardioselective
Vasodilator Property
Nebivolol
K+ Blocking Property Sotalol
K+ Opening Property Tilsolol
Selective β2 blocker Butoxamine
Non Catecholamine acting selectively on β Prenalterenol
BISPHOSPHONATES
1
st
Bisphosphonate Approved Etindronate
Treatment of Postmenopausal Osteoporosis Alendronate
Risendronate
Prevention of Steroid Induced Osteoporosis Risendronate
Unique Administration Technique
Once Yearly i.v/Once Monthly Oral
Zolendronate
Idandronate
Most Potent Drug for Treatment & Prevention of
Osteoporosis
Bisphosphonates
POINTS ABOUT DRUGS
www.medpgnotes.com
3CATARACT NUGGETS
CATARACT NUGGETS
Anterior Polar Perforation of corneal ulcer
Anterior Capsular Vossious ring
Anterior Subscapular Glaucoma
Posterior Polar Mittendorf dot
Posterior Capsular
Posterior Subcapsular Steroid
MC cause of blindness in India Cataract
MC cause of blindness in Adults Cataract
MC cause of blindness in children Keratomalacia
MC cause of cataract Age Related
MC Type of Congenital Cataract Punctate cataract
MC Health Disorder among Geriatrics Visual Impairment/Cataract
MC visually significant Congenital cataract Lamellar/Zonular cataract
Lens changes in Anterior Uveitis Complicated Cataract with Posterior Capsular Opacities
Second Sight Nuclear Cataract
Fluctuation of Refractory Error Diabetic Cataract
Complication of Intumescent Cataract Phacomorphic Glaucoma
Complication of Morgagnian cataract Phacolytic Glaucoma
Complication of Hypermature Sclerotic Cataract Subluxation/Dislocation of Lens
Phacoanaphylactic Uveitis
Cataract in Galactosemia is due to accumulation of Galactitiol
Cataract in Diabetes due to accumulation of Sorbitol
Galactosemia Oil Drop Cataract
MC Ocular Complication of Systemic Steroid Cataract
SPECIFIC CATARACT
Snow Flake Cataract Diabetes Mellitus
Sunflower Cataract Wilson’s disease
Chalcosis
Penetrating trauma
Vossious ring on anterior surface of lens
Rossette Shaped Cataract
Blunt Trauma
Christmas Tree cataract Myotonica Dystrophica
Oil drop Cataract Galactosemia
Morgagnian Cataract Hypermature Senile Cataract
Rainbow cataract
Breadcrumb Cataract
Polychromatic Lusture
Complicated Cataract
Snow Blindness Ultraviolet
Glass Blower’s Cataract Infrared

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Points about drugs sample

  • 2. POINTS ABOUT DRUGS www.medpgnotes.com 1 Contents ANTICHOLINESTERASE..................................................................................................................................................................................................................................2 AUTACOIDS..........................................................................................................................................................................................................................................................2 BETA BLOCKERS................................................................................................................................................................................................................................................2 BISPHOSPHONATES.........................................................................................................................................................................................................................................2 CATARACT NUGGETS.......................................................................................................................................................................................................................................3 CONDITION AND SPECIFIC DRUG...............................................................................................................................................................................................................4 CONDITION AND SPECIFIC SURGERY.......................................................................................................................................................................................................5 DIABETES NUGGETS ........................................................................................................................................................................................................................................6 DIFFERENT USAGE OF DRUGS.....................................................................................................................................................................................................................7 DRUG OF CHOICE...............................................................................................................................................................................................................................................7 DRUG KINETICS............................................................................................................................................................................................................................................... 11 FEW DRUG INTERACTIONS........................................................................................................................................................................................................................ 11 MECHANISM OF ACTION OF DRUGS....................................................................................................................................................................................................... 12 MONOCLONAL ANTIBODIES...................................................................................................................................................................................................................... 19 NITRATES NUGGET ....................................................................................................................................................................................................................................... 19 OPIOID NUGGET.............................................................................................................................................................................................................................................. 20 PRODRUGS ........................................................................................................................................................................................................................................................ 20 SAFEST DRUGS IN PREGNANCY NUGGET............................................................................................................................................................................................. 21 STEROID DRUGS ............................................................................................................................................................................................................................................. 21 TREATMENT OF CHOICE............................................................................................................................................................................................................................. 22
  • 3. POINTS ABOUT DRUGS www.medpgnotes.com 2ANTICHOLINESTERASE ANTICHOLINESTERASE Naturally occurring Anticholinesterase Lipid Soluble Anticholinesterase Blood brain barrier crossing Anticholinesterase Physostigmine Anticholinesterase used in Myasthenia Gravis Neostigmine/Pyridostigmine Anticholinesterase used for Diagnosis of Mtasthenia Gravis Edrophonium Anticancer showing Anticholinesterase Property Irinotecan AUTACOIDS FUNCTION AUTAOIDS Most Important chemical elevating Hypothalamic setpoint PGE2 Vasoconstrictor PGF2 Prostaglandins causing Renal Vasodilataion PGI2,PGE2 Vasodilatation in blood vessels PGI2,PGE2,PGF2α Platelet Aggregation TXA2 Inhibition of Platelet aggregation PGI2 Chemotactic LTB4 Bronchoconstrictor Slow reacting substance of anaphylaxis(SRSA) LTC4 LTD4 LTE4 BETA BLOCKERS Most Cardioselective Vasodilator Property Nebivolol K+ Blocking Property Sotalol K+ Opening Property Tilsolol Selective β2 blocker Butoxamine Non Catecholamine acting selectively on β Prenalterenol BISPHOSPHONATES 1 st Bisphosphonate Approved Etindronate Treatment of Postmenopausal Osteoporosis Alendronate Risendronate Prevention of Steroid Induced Osteoporosis Risendronate Unique Administration Technique Once Yearly i.v/Once Monthly Oral Zolendronate Idandronate Most Potent Drug for Treatment & Prevention of Osteoporosis Bisphosphonates
  • 4. POINTS ABOUT DRUGS www.medpgnotes.com 3CATARACT NUGGETS CATARACT NUGGETS Anterior Polar Perforation of corneal ulcer Anterior Capsular Vossious ring Anterior Subscapular Glaucoma Posterior Polar Mittendorf dot Posterior Capsular Posterior Subcapsular Steroid MC cause of blindness in India Cataract MC cause of blindness in Adults Cataract MC cause of blindness in children Keratomalacia MC cause of cataract Age Related MC Type of Congenital Cataract Punctate cataract MC Health Disorder among Geriatrics Visual Impairment/Cataract MC visually significant Congenital cataract Lamellar/Zonular cataract Lens changes in Anterior Uveitis Complicated Cataract with Posterior Capsular Opacities Second Sight Nuclear Cataract Fluctuation of Refractory Error Diabetic Cataract Complication of Intumescent Cataract Phacomorphic Glaucoma Complication of Morgagnian cataract Phacolytic Glaucoma Complication of Hypermature Sclerotic Cataract Subluxation/Dislocation of Lens Phacoanaphylactic Uveitis Cataract in Galactosemia is due to accumulation of Galactitiol Cataract in Diabetes due to accumulation of Sorbitol Galactosemia Oil Drop Cataract MC Ocular Complication of Systemic Steroid Cataract SPECIFIC CATARACT Snow Flake Cataract Diabetes Mellitus Sunflower Cataract Wilson’s disease Chalcosis Penetrating trauma Vossious ring on anterior surface of lens Rossette Shaped Cataract Blunt Trauma Christmas Tree cataract Myotonica Dystrophica Oil drop Cataract Galactosemia Morgagnian Cataract Hypermature Senile Cataract Rainbow cataract Breadcrumb Cataract Polychromatic Lusture Complicated Cataract Snow Blindness Ultraviolet Glass Blower’s Cataract Infrared