lecture of oral pathology

5. Amelo blastoma. Relative distribution of ameloblastomas in the jaws.

6. Ameloblastoma. A, Cross photograph of a mandibular resection specimen. B,
The radiograph of the specimen shows a large radiolucent defect associated
with an inferiorly displaced third molar.

7. Ameloblastoma. large expansile mass of the anterior mandible.

8. Ameloblastoma. Massive tumor of the anterior mandible.

10. Ameloblastoma. Prominent expansion of the lingual alveolus caused by a large
ameloblastoma of the mandibular symphysis.

12. Ameloblastoma. This small unilocular radiolucency lesion could easily be
mistaken for a lateral periodontal cyst.

13. Ameloblastoma. large multilocular lesion involving the mandibular angle and
ascending ramus. The large loculations show the "soap bubble" appearance. An
unerupted third molar has been displaced high into the ramus.

14. Ameloblastoma. Periapical films showing the "honeycombed" appearance.

15. Ameloblastoma. Destructive radiolucent lesion associated with
root resorption of the anterior teeth.

17. Amelobl astoma (follicular pattern). Multiple islands of odontogenic epithelium
demonstrating peripheral columnar differentiation with reverse polarization. The
central zones resemble stellate reticulumand exhibit foci of cystic degeneration.

19. Ameloblastoma (follicular pattern) . This photomicrograph highlights the peripheral
columnar cells exhibiting reverse polarization.

20. Ameloblastoma (plexiform pattern) . large anastomosing cords of
odontogenic epithelium. The high-power view(inset) reveals columnar cells
with reverse polarization.

21. • Ameloblastom a (acanthomatous pattern) . Islands of ameloblastoma
demonstrating central squamous differentiation.

23. Ameloblastoma (granular cell variant). Tumor islands exhibiting
cells with prominent granular cytoplasm.

25. Ameloblastoma (desmoplastic variant). Thin cords of ameloblastic
epithelium within a dense fibrous connective tissue stroma.

26. Desmoplastic ameloblastoma. Large irregular radiolucency
demonstrating focal radiopacities.

27. Ameloblastom a (basal cell variant ). Island of hyperchromatic basaloid cells.

28. Unicystic ameloblastoma (intraluminal ple xiform type). Corona l computed
tomography (CT) image that shows a large cystic lesion with an intraluminal mass
arising from the cyst wall (arrow).

29. Unicystic ameloblastoma. A large radiolucency in a 7-year-old boy with displacement of the
developing second molar to the inferior border of the mandible. This was believed to be a large
dentigerous cyst.

31. Unicystic ameloblastoma (luminal type). The cyst is lined by ameloblastic
epithelium showing a hyperchromatic. polarized basal layer. The overlying
epithelial cells are loosely cohesive and resemble stellate reticulum.

32. Unicystic ameloblastoma (intraluminal plexiform type). Photomicrograph of
the intraluminal mass arising from the cyst wall in the same patient shown in .
The inset shows the intraluminal mass at higher magnification.

33. Unicystic ameloblastoma (mural type). Islands of follicular ameloblastoma are
infiltrating into the fibrous connective tissue wall.

35. Peripheral ameloblastoma. Sessile gingival mass.

37. Peripheral ameloblastoma. Interconnecting cords of ameloblastic epithelium
filling the lamina propria.

38. Adenomatoid odontogenic tumor. Relative distribution of adenomatoid
odontogenic tumor in the jaws.

39. Adenomatoid odontogenic tumor. A well circumscribed solid mass can be seen
enveloping the crown of this tooth.

40. Adenomatoid odontogenic tumor (follicular type) . Radiolucent lesion involving an
unerupted mandibular first premolar. Fine snowflake calcifications are present in the
radiolucent area. In contrast to the usual dentigerous cyst. the radiclucency
extends almost to the apex of the tooth.

41. Adenomatoid odontogenic tumor (extra-follicular type) . A small radiolucency
is present between the roots of the lateral incisor and canine.

42. Adenomatoid odontogenic tumor. Low-power view demonstrating a thick
capsule surrounding the tumor.

43. Adenomatoid odontogenic tumor. Higher magnification showing the duct like
epithelial structures. The nuclei of the columnar calls are polarized away from
the central spaces.

44. Calcifying epithelial odontogenic tumor. Relative distribution of calcifying
epithelial odontogenic tumor in the jaws.

45. Calcifying epithelial odontogenic tumor. Prominent calcification around the crown of
an impacted second molar that is involved in the tumor.

46. Calcifying epithelial odontogenic tumor. Honeycombed multilocular radiolucency
containingfine calcifications.

47. Calcifying epithelial odontogenic tumor. Sheets of polyhedral tumor cells with
prominent eosinophilic cytoplasm and intercellular bridging. Pools of amorphous
eosinophilic amyloid are present. Multiple liesegang ring calcifications are seen in
the inset

48. Calcifying epithelial odontogenic tumor. With Congored staining. the pools of
amyloid exhibit an apple-green birefringence when viewed with polarized
light.

49. Squamous odontogenic tumor. Lucent defect extending along the roots of the
lateral incisor and first premolar teeth.

50. Squamous odontogenic tumor. Islands of bland appearing squamous epithelium in a
fibrous stroma. Micro-cyst formation is seen. The inset shows one of the tumor
islands at higher power.

51. Ameloblastic fibroma. Well-defined radiolucent defect associated with
an unerupted second molar.

52. Ameloblastic fibra-odontoma. Radiolucent defect in the ramus containing small
calcifications having the radio-density of tooth structure.

53. Ameloblastic fibroma. long, narrow cords of odontogenic epithelium
in a richly cellular, primitive mesenchymal stroma. Note the
peripheral columnar differentiation (inset).

54. Ameloblastic fibre-odontoma. The soft tissue component of the tumor is
indistinguishable from an ameloblastic fibroma. Developing rudimentary tooth like
structures are shown (inset).

55. Ameloblastic fibrosarcoma. An-old woman complained of facial
asymmetry and recent increase in size of a mandibular mass that had been
present for some years. B. Radiograph of the same patient. Note the lytic
destruction of the posterior mandible.

56. Ameloblastic fibrosarcoma. The cellular mesenchymal tissue shows hyperchromatism
and atypical cells.A small island of ameloblastic epithelium is present.

57. Compound odontom a. Surgical specimen consisting of more than 20 malformed
tooth like structures.

58. Compound odontoma. Multiple toothlets preventing the eruption of the mandibular
cuspid.

59. Compound odontoma. A small duster of tooth like structures is preventing the
eruption of the maxillary canine.

60. Complex odontoma. A large radiopaque mass is overlying the crown of the
mandibular right second molar, which has been displaced to the inferior border of
the mandible.

61. Complex odontoma. This decalcified section shows a disorganized mass of dentin
intermixed with small pools of ename lmatrix.

62. Odontogenic fibroma. Relative distribution of odontogenic fibroma in
the jaws.

63. Odontogenic fibroma. Apical radiolucent lesion in the incisor and premolar area.

64. Odontogenic fibroma (simple type). Scattered fibroblasts within a collagenous
background. No epithelial rests were found on multiple sections from this tumor.

66. Odontogenic fibroma (World Health Organization [WHO] type. A cellular
fibroblastic lesion containing narrow cords of odontogenic epithelium.

67. Granular cell odontogenic tumor. Radiolucent lesion involving the apical area
of endodontically treated maxillary teeth.

68. Granular cell odontogenic tumor. Sheet of large granular mesenchymal cells
with small nests of odontogenic epithelium.

69. Cementoblastoma. low-power photomicrograph showing the
tumor attached to the roots of the tooth.

70. Cementoblastoma. A. Adensely mineralized mass is seen at the apex of the
distal root of the first molar. The root is partially resorbed. B, The surgical
specimen shows that the mass is attached to the root.

71. Cementoblastoma around the
roots of a mandibular first molar.

72. Cementoblastoma. Mineralized tissue containing numerous
plump cementoblasts.

73. Cementoblastoma with a periphery showing numerous
pale cementoblasts (left) against a dense network of
cementum.

74. Odontogenic myxoma of the right mandible. Note malpositioned
third molar. B, Odontogenic myxoma of the maxilla with a widely
expansile quality containing an impacted tooth.

75. Odontogenic myxoma showing characteristic
multilocularity.

76. Odontogenic myxoma exhibiting typical bland myxoid appearance.

77. Odontogenic fibromyxoma with collagen bundles and residual bony trabecula
(center) evident.

78. Follicular sac with myxomatous change. Note residual reduced enamel epithelium
at top.

79. Ameloblastic carcinoma. A, Rapidly growing tumor showing prominent labial
expansion of the mandible in the incisor and premolar area. B, The panoramic
radiograph shows irregular destruction of the mandible.

80. Ameloblastic carcinoma. Ameloblastlc epithelium demonstrating hyper chromatism.
pleomorphism, and numerous mitotic figures.

81. Clear cell odontogenic carcinoma. Unilocular
radiolucent defect.

82. Clear cell odontogenic carcinoma. Tumor island demonstrating cells with a clear
cytoplasm. Note the peripheral columnar differentiation.