11. Oral wart. Immunohistochemical stain for common human
papillomavirus in an oral wart. Positive, brown-staining nuclei
are seen in upper level keratinocytes.
34. Squamous ce ll carcinoma. Metastatic deposits
within cervical lymph nodes present as firm, painless enlargements
as seen in this patient with metastasis to a superior jugular node
froma posterior lateral tongue carcinoma.
35. Well-differentiated squamous cell carcinoma.
l ow-power photomicrograph showing islands of malignant squamous
epithelium invading into the lamina properia.
40. Moderately differentiated squamous cell carcinoma.
Although no keratinization is seen in this medium-power
view, these malignant cells are still easily recognizable as being of
squamous epithelial origin.
41.
42.
43. Poorly differentiated squamous cell carcinoma.
The numerous pleomorphic cells within the lamina properia
represent anaplastic carcinoma.
54. l eu koplakia. Extensive ventra l and lateral tongue
lesion containing multiple areas representi ng various possible
pha ses or clinical appearances
55. Moderate epithelial dysplasia. Dysplast ic
changes extend to the midpo int of the ep ithelium and are character
ized by nuclear hyperchromatism. pleomorphism, and ce llular
crowding.
56.
57.
58. Ductal dysplasia. Salivary gland duct exhibiting
squamous metaplasia and dysplasia t hat originated from an overlying
surface epit helial dysplasia
65. Basal cell carcinom a. low- power photomicrograph
showing ulceration of the epidermal surface associated with
an invading tumor of hyperchromatic epithelial cells. Inset demonstratesislands
of basophilic epithelium with peripheral palisading.