Atrophy

1. By :
Mohamed Khalid Ali Newera
ALLPPT.com _ Free PowerPoint Templates, Diagrams and Charts

2. Definition
Mechanism
classification
How To Avoid Atrophy?

3. Definition
Decrease size of organ as a result of decrease
in both the number and size of the cells.
I’m Normal !
Atrophy Attack!:????

4. I’m Normal !
Atrophy Attack!:????

5. I’m Normal !
Atrophy Attack!:????

6. Example
Macroscopic:
1.Affected organ decrease in size
2.Appear : soft flabby
3.Color : pale
4.Capsule : wrinkled

7. Microscopic :
1. the cells in atrophic organs are smaller in size
2. Increase spaces between muscle fiber

8. Reduction in structural components of cell
Atrophy
Protein
synthesis
Mitochondria
&
myofilaments
Endoplasmic
reticulum
Protein
catabolism

10. 1)Physiological
1. Atrophy of thymus gland
2. thyroglossal duct after birth
3. atrophy of ovaries & uterus after menopause
4. Atrophy of uterus following child birth

11. 2)Pathological
1.Starvation
2.Neuropathic atrophy:
due to loss of innervation.
3. Senile atrophy : in old age

12. 2)Pathological
4.Pressure atrophy: due to long continued pressure on a
tissue leading to decrease in its blood supply with atrophy of its cells
e.g. amyloidosis of the liver
Amyloidosis liver

13. 2)Pathological
5.Ischemic atrophy:
due to decrease of blood supply
e.g. atherosclerosis
6.Decreased work load:
e.g. immobilized limb

14. How To Avoid Atrophy?
1. eating a healthy diet
2. getting regular, moderate exercise
3. avoiding smoking or quitting
4. Do not stay in one position for too long