Practical radiological approach to a case of intersex

2. • Intersex
• DSD = Disorders of Sex Development

3. • Disorders of sex development (DSDs) are congenital
conditions in which the development of
chromosomal, gonadal, or anatomic sex is atypical.

4. • DSDs can be classified broadly into four categories on the basis of
gonadal histologic features:
1. Female pseudohermaphroditism (46,XX with two ovaries)
2. Male pseudohermaphroditism (46,XY with two testes)
3. True hermaphroditism (ovotesticular DSD) (both ovarian and testicular
tissues)
4. Gonadal dysgenesis, either mixed (a testis and a streak gonad) or pure
(bilateral streak gonads).

8. TDF (testis determining factor)
Testis
MIS (müllerian inhibiting substance)Testosterone
Müllerian duct
Wolffian duct