Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Developmental Physiology of the Respiratory System

1,717 views

Published on

Developmental Physiology of the Respiratory System

Published in: Health & Medicine
  • I’ve personally never heard of companies who can produce a paper for you until word got around among my college groupmates. My professor asked me to write a research paper based on a field I have no idea about. My research skills are also very poor. So, I thought I’d give it a try. I chose a writer who matched my writing style and fulfilled every requirement I proposed. I turned my paper in and I actually got a good grade. I highly recommend ⇒ www.HelpWriting.net ⇐
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here
  • You might get some help from ⇒ www.WritePaper.info ⇐ Success and best regards!
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here
  • My personal experience with research paper writing services was highly positive. I sent a request to HelpWriting.net and found a writer within a few minutes. Because I had to move house and I literally didn’t have any time to sit on a computer for many hours every evening. Thankfully, the writer I chose followed my instructions to the letter. I know we can all write essays ourselves. For those in the same situation I was in, I recommend HelpWriting.net.
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here

Developmental Physiology of the Respiratory System

  1. 1. Developmental Physiology of the Respiratory System Mohammad Rezaei Pediatric Pulmonologist
  2. 2. Lung Development • Prenatal Development • Postnatal Development and Growth
  3. 3. Prenatal Development of the Lung
  4. 4. Prenatal Development of the Lung
  5. 5. Prenatal Development of the Lung Embryonic stage
  6. 6. Prenatal Development of the Lung Pseudoglandular stage
  7. 7. Prenatal Development of the Lung Canalicular stage
  8. 8. Prenatal Development of the Lung Saccular stage
  9. 9. Prenatal Development of the Lung Alveolar stage
  10. 10. Birth • Lung Fluid • Pulmonary Blood Flow
  11. 11. Postnatal Development and Growth of the Lung
  12. 12. Postnatal Development of the Lung Alveolarization Microvascular Maturation
  13. 13. Postnatal Growth of the Lung Postnatal lung growth continue throughout infancy and childhood and into the adolescent years.
  14. 14. Chest Wall & Diaphragm • Chest wall compliance • Diaphragm and respiratory muscles (type of fibers)
  15. 15. Chest Wall Configuration
  16. 16. Chest Wall Configuration
  17. 17. Normal values for pulmonary function with age • predicted values of pulmonary function depend upon age, height, gender, and race . • Lung Capacities and flows continue to increase until late adolescence. (then decrease) • Lung Volume, Gas exchange surface area, Diffusion capacity,…all increase in relation of body mass increase.
  18. 18. Normal values for pulmonary function with age Compliance • Chest wall • Lung
  19. 19. Normal values for pulmonary function with age Resistance • Airway diameter (r) The diameter of airways in infants and children is much smaller than adults, resulting in increased Raw • Number of airways • RR • Lung Volume Site of Airway Resistance • In the infant lung, small peripheral airways may contribute as much as 50% of the total airway resistance, and this proportion does not decrease until about 5 years of age. (Remember small airway diseases such as Bronchiolitis)
  20. 20. Normal values for pulmonary function with age Total Lung Capacity • Lung volume is linearly related to body length during childhood
  21. 21. Normal values for pulmonary function with age Functional residual capacity • in the infants predicts a supine FRC of only 10% of TLC, whereas in adults FRC accounts for approximately 50% of TLC in the upright position. • In infants, the post inspiratory activity of the inspiratory muscles and the laryngeal control of expiratory flow ( “grunting” ) modify respiratory mechanics to maintain the patency of small airways and alveoli. • Mean values for FRC range from 20-25 mL/kg in infants up to 18 months of age
  22. 22. Normal values for pulmonary function with age Tidal Volume Respiratory Rate
  23. 23. Normal values for pulmonary function with age Minute Ventilation Minute Ventilation = Tidal Volume x Respiratory Rate
  24. 24. Normal values for pulmonary function with age
  25. 25. Thank you

×