1. MAJOR DISORDERS OF THE ENDOCRINE SYSTEM Nio C. Noveno, RN, MAN

4. HORMONE REGULATION: NEGATIVE FEEDBACK MECHANISM

6. ANTERIOR PITUITARY DISORDERS

12. HYPERPITUITARISM: CLINICAL MANIFESTATIONS

19. POSTERIOR PITUITARY DISORDERS

28. THYROID DISORDERS

41. HYPERTHYROIDISM: CLINICAL MANIFESTATIONS

56. PARATHYROID DISORDERS

65. T rousseau’s & Chvostek’s E levated serum PO 4 ; low Ca 2+ T ingling A lkalosis; Arrhythmias N arrowing of airway I rritability C ramps

67. T C AKE ARE ETANY RACHEOSTOMY ALCIUM GLUCONATE ALCIUM 8.6 – 10.6 mg / dL

68. PHEOCHROMOCYTOMA

69. ADRENAL GLANDS

73. PHEOCHROMOCYTOMA BP HR Diaphoresis BMR VMA Glucose

76. ADDISON'S DISEASE

87. ADDISON’S DISEASE

89. CUSHING'S SYNDROME

93. CUSHING’S SYNDROME

97. DIABETES MELLITUS

102. P olyuria olydipsia olyphagia ruritus aresthesia oor healing oor eyesight

103. Normal Impaired DM FBS <110mg/dl 110-125mg/dl ≥ 126mg/dl 2H OGTT <140mg/dl ≥ 140; <200mg/dl ≥ 200 mg/dl

106. Insulin Onset Peak Duration Ultra rapid acting insulin analog (humalog) 10-15 min 1 H 3 H SAI (humulin regular) ½ - 1 H 2-4 H 4-6 (8) H IAI (humulin lente, Humulin NPH) 3-4 H 4-12 H 16-20 H LAI (Protamine zinc, humulin ultralente) 6-8 H 12-16 H 20-30 H Premixed insulin (NPH-regular [80-20, 70-30, 50-50]) ½-1 H 2-12 H 18-24 hrs Insulin glargine (Lantus ) Slower than NPH No Peak 24 H

130. MAJOR DISORDERS OF THE ENDOCRINE SYSTEM THANK YOU! Nio C. Noveno, RN, MAN