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• DIAGNOSIS
• MONITORING
ASSESSMENT OF
OCCUPATIONAL ASTHMA
 History of exposure to sensitizing agents
 Absence of asthma symptoms before beginning
employment
 Documented relationship between symptoms and
workplace (improving symptom when away from work
& worsening symptoms upon return to work
HISTORY
2/99 3
WHAT SYMPTOMS SHOULD YOU LOOK
OUT FOR?
 The symptoms start as
 runny eyes and nose
 itchy eyes and nose
 and may develop into the more serious problems of
asthma
 breathlessness
 wheezing
 tightness of chest
 coughing
DIAGNOSING OCCUPATIONAL ASTHMA
History
Investigation
Detailed history of past & present
occupational exposures
Cough – at work/ end of shift,
precedes wheezing
Concurrent – rhinorrhoea,
nasal congestion,
lacrimation, conjunctivitis
Symptoms improve – at weekends &
holidays, persist – advanced stage.
Diagram – Spirometry
Parameters
Procedure
Diagnosis
SPIROMETRY
 FEV1 (Forced expiratory volume in 1 second)
 Forced Vital Capacity (FVC)
 FEV1/FVC ratio
PARAMETERS
Marked reduced in FEV1
Reduced in FVC
The FEV1/ FVC ratio is reduced
Significant improvement of the FEV 1 (>12%)
following administration of a bronchodilator
Diurnal variability
DIAGNOSIS
Measure expiration
Easy
Steps
PEAK EXPIRATORY FLOW METER
STEPS TO USE PEAK EXPIRATORY FLOW
METER
1. Stand up or sit up straight.
2. Make sure the indicator is at the bottom of the meter
(zero).
3. Take a deep breath in, filling the lungs completely.
4. Place the mouthpiece in your mouth; lightly bite with your
teeth and close your lips on it. Be sure your tongue is away
from the mouthpiece.
5. Blast the air out as hard and as fast as possible in a single
blow.
6. Remove the meter from your mouth.
7. Record the number that appears on the meter and then
repeat steps one through seven two times.
8. Record the highest of the three readings in an asthma
diary. This reading is your peak expiratory flow (PEF).
Similar with asthma
Differs according to the severity :
1. PEF > 75% of predicted or best value (MILD)
2. PEF between 50% – 75% of predicted or best
value (MODERATE)
3. PEF < 50% of predicted or best value
(SEVERE)
4. PEF < 30% of predicted or best value
 Reversibility testing
DIAGNOSIS
Pharmacological therapy for OA is
identical to therapy for other
forms of asthma, but it is not
substitute for adequate avoidance
PHARMACOLOGICAL THERAPY
(Bateman, et al, 2008)
PHARMACOLOGICAL THERAPY
Treatment
Controllers Relievers
1) Inhaled glucocorticosteroids 1) Rapid-acting inhaled b2-agonists
2) Leukotriene modifiers 2) Anticholinergics
3) Long-acting inhaled b2-agonists 3) Short-acting oral b2-agonists
4) Theophylline
5) Anti-IgE
6) Others
Systemic glucocorticosteroids
Oral anti-allergic compounds
2/99 16
OCCUPATIONAL ASTHMA CHECKLIST
Reminder, if you have trouble with
wheezing, coughing or shortness of breath
at work, you could have occupational
asthma:
 Consult your physician. He or she may suggest a lung function test.
 See your work supervisor for details about potential hazards in your work
environment.
 Have the tests and evaluation required to prove the suspected
occupational asthma and its cause.
 Seek your physician's advice about therapy for occupational asthma.
 Pre employment stage: asked about pre existing
asthma (not suitable for this work)
 Lung function test and referral for immunological
blood test or skin prick test may be appropriate
 Frequent health surveillance indicated
 First few years of exposure (OA risk greatest during early years)
 Workers with pre existing asthma
 Workers who develop rhinitis & workplace exposure should be
investigated and reduced
HEALTH SURVEILLANCE

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Assessment of occupational asthma

  • 2.  History of exposure to sensitizing agents  Absence of asthma symptoms before beginning employment  Documented relationship between symptoms and workplace (improving symptom when away from work & worsening symptoms upon return to work HISTORY
  • 3. 2/99 3 WHAT SYMPTOMS SHOULD YOU LOOK OUT FOR?  The symptoms start as  runny eyes and nose  itchy eyes and nose  and may develop into the more serious problems of asthma  breathlessness  wheezing  tightness of chest  coughing
  • 4. DIAGNOSING OCCUPATIONAL ASTHMA History Investigation Detailed history of past & present occupational exposures Cough – at work/ end of shift, precedes wheezing Concurrent – rhinorrhoea, nasal congestion, lacrimation, conjunctivitis Symptoms improve – at weekends & holidays, persist – advanced stage.
  • 6.
  • 7.
  • 8.
  • 9.  FEV1 (Forced expiratory volume in 1 second)  Forced Vital Capacity (FVC)  FEV1/FVC ratio PARAMETERS
  • 10. Marked reduced in FEV1 Reduced in FVC The FEV1/ FVC ratio is reduced Significant improvement of the FEV 1 (>12%) following administration of a bronchodilator Diurnal variability DIAGNOSIS
  • 12. STEPS TO USE PEAK EXPIRATORY FLOW METER 1. Stand up or sit up straight. 2. Make sure the indicator is at the bottom of the meter (zero). 3. Take a deep breath in, filling the lungs completely. 4. Place the mouthpiece in your mouth; lightly bite with your teeth and close your lips on it. Be sure your tongue is away from the mouthpiece. 5. Blast the air out as hard and as fast as possible in a single blow. 6. Remove the meter from your mouth. 7. Record the number that appears on the meter and then repeat steps one through seven two times. 8. Record the highest of the three readings in an asthma diary. This reading is your peak expiratory flow (PEF).
  • 13. Similar with asthma Differs according to the severity : 1. PEF > 75% of predicted or best value (MILD) 2. PEF between 50% – 75% of predicted or best value (MODERATE) 3. PEF < 50% of predicted or best value (SEVERE) 4. PEF < 30% of predicted or best value  Reversibility testing DIAGNOSIS
  • 14. Pharmacological therapy for OA is identical to therapy for other forms of asthma, but it is not substitute for adequate avoidance PHARMACOLOGICAL THERAPY (Bateman, et al, 2008)
  • 15. PHARMACOLOGICAL THERAPY Treatment Controllers Relievers 1) Inhaled glucocorticosteroids 1) Rapid-acting inhaled b2-agonists 2) Leukotriene modifiers 2) Anticholinergics 3) Long-acting inhaled b2-agonists 3) Short-acting oral b2-agonists 4) Theophylline 5) Anti-IgE 6) Others Systemic glucocorticosteroids Oral anti-allergic compounds
  • 16. 2/99 16 OCCUPATIONAL ASTHMA CHECKLIST Reminder, if you have trouble with wheezing, coughing or shortness of breath at work, you could have occupational asthma:  Consult your physician. He or she may suggest a lung function test.  See your work supervisor for details about potential hazards in your work environment.  Have the tests and evaluation required to prove the suspected occupational asthma and its cause.  Seek your physician's advice about therapy for occupational asthma.
  • 17.  Pre employment stage: asked about pre existing asthma (not suitable for this work)  Lung function test and referral for immunological blood test or skin prick test may be appropriate  Frequent health surveillance indicated  First few years of exposure (OA risk greatest during early years)  Workers with pre existing asthma  Workers who develop rhinitis & workplace exposure should be investigated and reduced HEALTH SURVEILLANCE