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Rapid Sequence Intubation
              Paleerat Jariyakanjana, MD
                    Emergency Physician
             Naresuan University Hospital
Decision to Intubate
1) Failure to maintain or protect the
   airway
2) failure of ventilation or oxygenation
3) the patient’s anticipated clinical
   course and likelihood of
   deterioration
Administration of a potent sedative
 (induction) agent and an NMBA without
 interposed assisted ventilation

       positive-pressure ventilation
                      
       air to pass into the stomach
                      
             gastric distention
                      
    risk of regurgitation & aspiration
Requires preoxygenation phase
permits pharmacologic control of the
 physiologic responses to
 laryngoscopy and
 intubation, mitigating potential
 adverse effects
     Increase ICP
     sympathetic discharge
Preparation
assessed for intubation difficulty
determining dosages and sequence
 of drugs, tube size, and laryngoscope
 type, blade and size
continuous cardiac monitoring and
 pulse oximetry
≥1 good-quality IV lines
Redundancy is always desirable in
 case of equipment or IV access
 failure.
Preparation
Preoxygenation
100% oxygen for 3 minutes of
 normal, tidal volume breathing
normal, healthy adult establishes an
 adequate oxygen reservoir to permit
 8 minutes of apnea before oxygen
 desaturation to less than 90% occurs
“no bagging”
time is insufficient
     8 vital capacity breaths using high-flow
      oxygen
Pretreatment
drugs are before administration of
 the succinylcholine & induction agent
mitigate the effects of laryngoscopy
 and intubation on the patient’s
 presenting or comorbid conditions
Intubation
     sympathetic discharge
     elevation of ICP
     reactive bronchospasm
     Bradycardia: children
Pretreatment
Paralysis with Induction
rapid IV push
immediately followed by rapid
 administration of intubating dose of
 NMBA
wait 45 s from the time the
 succinylcholine is given to allow
 sufficient paralysis to occur
Paralysis with Induction




                 Tintinalli's Emergency Medicine, 7e
Paralysis with Induction




                 Tintinalli's Emergency Medicine, 7e
Paralysis with Induction




                 Tintinalli's Emergency Medicine, 7e
Positioning
The patient should be positioned for
 intubation as consciousness is lost.
Sniffing position: head
 extension, neck flexion
Positioning
Sellick’s maneuver
     application of firm backward-directed
      pressure over the cricoid cartilage
     minimize the risk of passive regurgitation
      and, hence, aspiration
after administration of the induction
 agent and NMBA  BMV should not
 be initiated unless O2 sat ≤ 90%
Placement of Tube
assessed most easily by moving the
 mandible to test for absence of
 muscle tone
O2 sat is approaching 90%, the pt
 may be ventilated
When BMV is performed, Sellick’s
 maneuver is advisable
As soon as the ETT is placed, the cuff
 should be inflated and its position
 confirmed
Postintubation Management
CXR
use of long-acting NMBAs
 (e.g., pancuronium, vecuronium)
 toward optimal management using
 opioid analgesics and sedative
 agents to facilitate mechanical
 ventilation
ANY QUESTIONS?

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Rapid sequence intubation

  • 1. Rapid Sequence Intubation Paleerat Jariyakanjana, MD Emergency Physician Naresuan University Hospital
  • 2. Decision to Intubate 1) Failure to maintain or protect the airway 2) failure of ventilation or oxygenation 3) the patient’s anticipated clinical course and likelihood of deterioration
  • 3.
  • 4. Administration of a potent sedative (induction) agent and an NMBA without interposed assisted ventilation positive-pressure ventilation  air to pass into the stomach  gastric distention  risk of regurgitation & aspiration
  • 5. Requires preoxygenation phase permits pharmacologic control of the physiologic responses to laryngoscopy and intubation, mitigating potential adverse effects  Increase ICP  sympathetic discharge
  • 6.
  • 7. Preparation assessed for intubation difficulty determining dosages and sequence of drugs, tube size, and laryngoscope type, blade and size continuous cardiac monitoring and pulse oximetry ≥1 good-quality IV lines Redundancy is always desirable in case of equipment or IV access failure.
  • 9. Preoxygenation 100% oxygen for 3 minutes of normal, tidal volume breathing normal, healthy adult establishes an adequate oxygen reservoir to permit 8 minutes of apnea before oxygen desaturation to less than 90% occurs “no bagging” time is insufficient  8 vital capacity breaths using high-flow oxygen
  • 10. Pretreatment drugs are before administration of the succinylcholine & induction agent mitigate the effects of laryngoscopy and intubation on the patient’s presenting or comorbid conditions Intubation  sympathetic discharge  elevation of ICP  reactive bronchospasm  Bradycardia: children
  • 12. Paralysis with Induction rapid IV push immediately followed by rapid administration of intubating dose of NMBA wait 45 s from the time the succinylcholine is given to allow sufficient paralysis to occur
  • 13. Paralysis with Induction Tintinalli's Emergency Medicine, 7e
  • 14. Paralysis with Induction Tintinalli's Emergency Medicine, 7e
  • 15. Paralysis with Induction Tintinalli's Emergency Medicine, 7e
  • 16. Positioning The patient should be positioned for intubation as consciousness is lost. Sniffing position: head extension, neck flexion
  • 17. Positioning Sellick’s maneuver  application of firm backward-directed pressure over the cricoid cartilage  minimize the risk of passive regurgitation and, hence, aspiration after administration of the induction agent and NMBA  BMV should not be initiated unless O2 sat ≤ 90%
  • 18. Placement of Tube assessed most easily by moving the mandible to test for absence of muscle tone O2 sat is approaching 90%, the pt may be ventilated When BMV is performed, Sellick’s maneuver is advisable As soon as the ETT is placed, the cuff should be inflated and its position confirmed
  • 19. Postintubation Management CXR use of long-acting NMBAs (e.g., pancuronium, vecuronium) toward optimal management using opioid analgesics and sedative agents to facilitate mechanical ventilation
  • 20.