gall bladder histology and

1. SEMEY STATE MEDICAL
UNIVERSITY
TOPIC-HISTOLOGY OF GALL BLADDER AND BILIARY WAYS
Prerared by –Sohan patel
GROUP- 344
3RD COURSE GMF

2. Consists of:
- Mucosa
- Muscularis / Fibromuscular layer
- Serosa / Adventitia

3. Mucosa:
• It includes the lining epithelium of
simple columnar variety.
• Lamina propria rich in elastic fibers
and blood vessels.
• Presence of microvilli gives brush
border appearance to the epithelium
under light microscope, Which
facilitates absorption of water.
• Mucosa thrown into small folds when
the bladder is empty.

4. Muscularis:
• This layer consists of circularly
arranged smooth muscle fibers
intermixed with connective
tissue rich in elastic fibers.
 the neck of the gallbladder, the
lamina propria houses simple
tubuloalveolar glands, which
produce a small amount of
mucus.
Lamina Propria
Muscularis Layer
Loose connective tissue

5. Serosa/Adventitia:
• Fundus and lower surface of
body of gall bladder is covered
by peritoneum.
• Upper surface is attached to
the fossa for gall bladder by
means of connective tissue.

6. There is no:
 Muscularis mucosa
&
 Submucosa.

7. • The main function of the gallbladder is to store bile, concentrate it by absorbing
its water, and release it when necessary into the digestive tract.
• This process depends on an active sodium-transporting mechanism in the
gallbladder's epithelium. Water absorption is an osmotic consequence of the
sodium pump.
• Contraction of the smooth muscle of the gallbladder is induced by
(cholecystokinin), a hormone produced by enteroendocrine cells located in the
epithelial lining of the small intestine.
 Release of cholecystokinin is, in turn, stimulated by the presence of dietary fats in
the small intestine.

8. Histological structure of hepatic,
cystic, and common bile ducts
Mucosa:
Epithelial lining:
Simple columnar epithelium.
Lamina propria:
Thin.
Musculosa:
• Thin layer of smooth muscles that becomes thicker near the
duodenum and finally, in the intramural portion

9. THANK YOU FOR ATTENTION