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UTERINE RELAXANTS
These are the drugs which decrease uterine motility. USES:  Delay or postpone labour. Arrest abortion Dysmenorrhoea Suppression of labour allowed foetus to  mature. Premature labour is done only if cervical dilation is  < 4 cm
Contraindications: ,[object Object],[object Object],[object Object],[object Object]
CLASSIFICATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adrenergic agonist ,[object Object],[object Object],[object Object],[object Object],[object Object]
Side effects: Cardiovascular, metabolic complication, anxiety, restlessness, headache. NOT USED :  Diabetic, heart disease, steroids or  β  blockers.   ,[object Object],[object Object],[object Object],[object Object]
DOSE : 10 mg oral every 20- 30 min. till contraction ceases followed by 10 mg 6 hourly. Side effects: Tachycardia and hypotension 3)  Magnesium sulfate  :  Control convulsions and reduce BP in toxaemia of pregnancy. Drug of choice : prevention and t/t of seizure in preclampsia and eclampsia
[object Object],[object Object],[object Object],  DOSE:  i.v. bolus (2- 4 gm over10 - 20 min.) followed by 1 gm/hr i.v. infusion. Toxicity induce cardiac arrhythmia, paralysis, CNS and respiratory depression in mother and neonates .
5) Miscellaneous drugs ,[object Object],[object Object],[object Object]

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Uterine relaxation

  • 2. These are the drugs which decrease uterine motility. USES: Delay or postpone labour. Arrest abortion Dysmenorrhoea Suppression of labour allowed foetus to mature. Premature labour is done only if cervical dilation is < 4 cm
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. DOSE : 10 mg oral every 20- 30 min. till contraction ceases followed by 10 mg 6 hourly. Side effects: Tachycardia and hypotension 3) Magnesium sulfate : Control convulsions and reduce BP in toxaemia of pregnancy. Drug of choice : prevention and t/t of seizure in preclampsia and eclampsia
  • 8.
  • 9.