Neuro clinics 34 migraine 1

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Pratyush Chaudhuri

one of two part discussion of migraine headache dr Pratyush Chaudhuri. www.drpratyush.hpage.com for comments.

Health & Medicine

NEJM 2002; 346(4): 257-269; XI Congress of the IHS, 2004

Migraine Without Aura Migraine With Aura No aura or Prodrome Aura or prodrome is present Unilateral throbbing headache may be accompanied by nausea and vomiting Unilateral throbbing headache and later becomes generalised During headache, patient complains of phonophobia and photophobia Patient complains of visual disturbances and may have mood variations

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The rigid cranial vault contains brain tissue (1,400 g), blood (75 ml), and CSF (75 ml) The volume and pressure of these three components are usually in a state of equilibrium and produce the ICP. ICP is usually measured in the lateral ventricles; normal ICP is 10 to 20 mm hg. The Monro-kellie hypothesis states that because of the limited space for expansion within the skull, an increase in any one of the components causes a change in the volume of the others. Increased ICP is a syndrome that affects many patients with acute neurologic conditions. This is because pathologic conditions alter the relationship between intracranial volume and pressure. Although an elevated ICP is most commonly associated with head injury, it also may be seen as a secondary effect in other conditions, such as brain tumors, subarachnoid hemorrhage, and toxic and viral encephalopathies.

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Headache disorders are among the most common nervous system ailments, which are characterized by persistent headaches. Headache is a severe and disabling symptom of a few major headache disorders, including migraine, tension type headache, and cluster headache. Migraine is caused by spontaneous over activity and aberrant amplification in pain and other, primarily sensory, pathways in the brainstem. The current consensus is that the cause is predominantly neurological. According to current knowledge, a basic neuronal malfunction causes a series of intracranial and extra cranial alterations that cause migraine, comprising the four phases of premonitory symptoms, aura, headache, and postdrome. The effective diagnosis and treatment may help the patient improve in their quality of life and help to achieve an optimal therapeutic outcome. The scope of this review is to describe Migraine, types, etiology, pathophysiology, diagnosis, pharmacological treatment, non pharmacological treatment, and its prevention. C Andly Chedrick | D N Ashritha | Harini R "A Review Migraine" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-3 , April 2022, URL: https://www.ijtsrd.com/papers/ijtsrd49928.pdf Paper URL: https://www.ijtsrd.com/medicine/other/49928/a-review-migraine/c-andly-chedrick

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